Mus musculus

0 known processes

Grap

GRB2-related adaptor protein

(Aliases: 8430435N19Rik,BB233594)

Grap biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.182
Fly
amine metabolic process GO:0009308 45 0.114
immune effector process GO:0002252 321 0.107
ribonucleoside triphosphate metabolic process GO:0009199 220 0.088
regulation of hydrolase activity GO:0051336 246 0.087
nucleobase containing small molecule metabolic process GO:0055086 352 0.085
purine nucleotide metabolic process GO:0006163 302 0.081
small gtpase mediated signal transduction GO:0007264 97 0.079
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.078
nucleoside phosphate catabolic process GO:1901292 222 0.077
nucleotide metabolic process GO:0009117 332 0.077
guanosine containing compound catabolic process GO:1901069 144 0.073
cellular ketone metabolic process GO:0042180 84 0.072
regulation of cellular amine metabolic process GO:0033238 20 0.071
organonitrogen compound catabolic process GO:1901565 264 0.071
nucleoside triphosphate metabolic process GO:0009141 230 0.070
cellular amino acid metabolic process GO:0006520 103 0.070
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.070
purine nucleotide catabolic process GO:0006195 211 0.069
ribonucleoside metabolic process GO:0009119 245 0.068
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.068
cellular amine metabolic process GO:0044106 44 0.068
positive regulation of cellular amine metabolic process GO:0033240 5 0.067
cytokine production GO:0001816 319 0.067
purine nucleoside metabolic process GO:0042278 241 0.066
heterocycle catabolic process GO:0046700 280 0.066
ribonucleotide metabolic process GO:0009259 291 0.065
purine ribonucleotide metabolic process GO:0009150 290 0.064
nucleotide catabolic process GO:0009166 217 0.064
positive regulation of gtp catabolic process GO:0033126 85 0.064
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.063
purine ribonucleoside metabolic process GO:0046128 241 0.063
ribose phosphate metabolic process GO:0019693 291 0.062
regulation of cellular amino acid metabolic process GO:0006521 5 0.061
cell adhesion GO:0007155 329 0.057
ribonucleotide catabolic process GO:0009261 208 0.056
cellular nitrogen compound catabolic process GO:0044270 280 0.056
purine containing compound catabolic process GO:0072523 213 0.055
glycosyl compound catabolic process GO:1901658 206 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
purine ribonucleotide catabolic process GO:0009154 208 0.054
nucleoside metabolic process GO:0009116 246 0.054
purine nucleoside triphosphate catabolic process GO:0009146 203 0.053
guanosine containing compound metabolic process GO:1901068 144 0.051
aromatic compound catabolic process GO:0019439 286 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.051
nucleoside catabolic process GO:0009164 206 0.050
positive regulation of cellular catabolic process GO:0031331 148 0.050
ribonucleoside triphosphate catabolic process GO:0009203 199 0.050
purine nucleoside catabolic process GO:0006152 205 0.050
regulation of cellular catabolic process GO:0031329 242 0.050
regulation of gtp catabolic process GO:0033124 113 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
nucleoside triphosphate catabolic process GO:0009143 205 0.049
purine ribonucleoside catabolic process GO:0046130 205 0.049
regulation of nucleoside metabolic process GO:0009118 130 0.048
carbohydrate derivative catabolic process GO:1901136 231 0.048
regulation of nucleotide catabolic process GO:0030811 122 0.046
regulation of purine nucleotide catabolic process GO:0033121 122 0.046
lymphocyte mediated immunity GO:0002449 139 0.046
glycosyl compound metabolic process GO:1901657 246 0.045
purine containing compound metabolic process GO:0072521 311 0.044
regulation of lymphocyte activation GO:0051249 240 0.043
positive regulation of protein phosphorylation GO:0001934 242 0.043
positive regulation of gtpase activity GO:0043547 85 0.042
organophosphate catabolic process GO:0046434 232 0.041
positive regulation of hydrolase activity GO:0051345 148 0.041
regulation of transferase activity GO:0051338 263 0.040
Fly
regulation of nucleotide metabolic process GO:0006140 169 0.040
regulation of cell adhesion GO:0030155 154 0.040
g protein coupled receptor signaling pathway GO:0007186 243 0.040
mapk cascade GO:0000165 281 0.040
Mouse Fly
gtp catabolic process GO:0006184 143 0.039
positive regulation of nucleotide catabolic process GO:0030813 88 0.039
ribonucleoside catabolic process GO:0042454 206 0.038
regulation of mapk cascade GO:0043408 248 0.038
Mouse Fly
inflammatory response GO:0006954 244 0.037
regulation of cytokine production GO:0001817 266 0.037
positive regulation of protein modification process GO:0031401 299 0.037
regulation of purine nucleotide metabolic process GO:1900542 169 0.036
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.036
gtp metabolic process GO:0046039 144 0.035
positive regulation of nucleoside metabolic process GO:0045979 91 0.035
regulation of cell activation GO:0050865 289 0.035
cation transport GO:0006812 399 0.035
adaptive immune response GO:0002250 155 0.033
peptidyl amino acid modification GO:0018193 336 0.033
Fly
rho protein signal transduction GO:0007266 32 0.033
positive regulation of ras gtpase activity GO:0032320 65 0.031
lymphocyte differentiation GO:0030098 242 0.031
apoptotic signaling pathway GO:0097190 306 0.031
endocytosis GO:0006897 168 0.030
Yeast Worm
leukocyte mediated immunity GO:0002443 174 0.030
leukocyte differentiation GO:0002521 342 0.030
immune response activating signal transduction GO:0002757 116 0.029
regulation of ras gtpase activity GO:0032318 88 0.028
regulation of protein localization GO:0032880 231 0.028
regulation of organelle organization GO:0033043 289 0.028
Mouse
activation of immune response GO:0002253 138 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.027
regulation of defense response GO:0031347 233 0.027
immune response regulating signaling pathway GO:0002764 125 0.027
negative regulation of molecular function GO:0044092 258 0.026
Fly
intracellular protein transport GO:0006886 204 0.025
leukocyte proliferation GO:0070661 172 0.025
defense response to other organism GO:0098542 197 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
negative regulation of immune system process GO:0002683 209 0.024
regulation of secretion by cell GO:1903530 249 0.024
regulation of t cell activation GO:0050863 170 0.024
leukocyte activation involved in immune response GO:0002366 126 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
Fly
innate immune response GO:0045087 157 0.023
cell activation involved in immune response GO:0002263 126 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
actin cytoskeleton organization GO:0030036 220 0.023
Yeast Mouse Fly
cell type specific apoptotic process GO:0097285 268 0.023
positive regulation of cytokine production GO:0001819 174 0.022
response to lipopolysaccharide GO:0032496 128 0.022
oxidation reduction process GO:0055114 342 0.022
cellular protein complex assembly GO:0043623 116 0.022
Yeast Mouse
chemotaxis GO:0006935 247 0.022
organelle assembly GO:0070925 177 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
dna metabolic process GO:0006259 303 0.022
regulation of kinase activity GO:0043549 249 0.022
Fly
regulation of establishment of protein localization GO:0070201 181 0.022
muscle tissue development GO:0060537 308 0.022
response to organonitrogen compound GO:0010243 246 0.022
cytoplasmic transport GO:0016482 234 0.021
maintenance of location GO:0051235 89 0.021
Worm
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.021
multicellular organismal signaling GO:0035637 91 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
Mouse
positive regulation of transferase activity GO:0051347 167 0.021
axonogenesis GO:0007409 274 0.021
regulation of body fluid levels GO:0050878 162 0.021
protein localization to organelle GO:0033365 185 0.021
membrane organization GO:0061024 245 0.021
protein catabolic process GO:0030163 221 0.021
regulation of secretion GO:0051046 274 0.021
regulation of ion transport GO:0043269 215 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
transmembrane transport GO:0055085 412 0.020
calcium ion transport GO:0006816 159 0.020
male gamete generation GO:0048232 285 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
sensory organ morphogenesis GO:0090596 242 0.020
Fly
divalent inorganic cation transport GO:0072511 178 0.020
wnt signaling pathway GO:0016055 188 0.020
regulation of cell projection organization GO:0031344 206 0.020
Worm
regulation of membrane potential GO:0042391 192 0.020
homeostasis of number of cells GO:0048872 210 0.019
macromolecule catabolic process GO:0009057 281 0.019
positive regulation of defense response GO:0031349 124 0.019
response to molecule of bacterial origin GO:0002237 143 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
Mouse
regulation of actin filament based process GO:0032970 99 0.019
Mouse
negative regulation of cellular component organization GO:0051129 194 0.019
regulation of leukocyte mediated immunity GO:0002703 104 0.019
carbohydrate homeostasis GO:0033500 128 0.019
cellular homeostasis GO:0019725 240 0.019
fat cell differentiation GO:0045444 160 0.019
cellular lipid metabolic process GO:0044255 323 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
neuronal action potential GO:0019228 54 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
action potential GO:0001508 78 0.018
epithelial cell proliferation GO:0050673 174 0.018
cation homeostasis GO:0055080 212 0.018
protein processing GO:0016485 163 0.018
protein targeting GO:0006605 143 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
synaptic transmission GO:0007268 329 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
Fly
negative regulation of cell proliferation GO:0008285 296 0.017
divalent metal ion transport GO:0070838 172 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
cation transmembrane transport GO:0098655 266 0.017
protein maturation GO:0051604 176 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
Fly
organelle localization GO:0051640 179 0.017
regulation of rho protein signal transduction GO:0035023 71 0.017
protein secretion GO:0009306 111 0.017
regulation of inflammatory response GO:0050727 147 0.017
t cell activation GO:0042110 289 0.017
Mouse
blood circulation GO:0008015 195 0.017
lymphocyte proliferation GO:0046651 164 0.017
positive regulation of immune effector process GO:0002699 107 0.017
gland development GO:0048732 330 0.016
transmission of nerve impulse GO:0019226 76 0.016
regulation of interleukin 8 production GO:0032677 3 0.016
b cell activation GO:0042113 161 0.016
single organism cell adhesion GO:0098602 156 0.016
regulation of homeostatic process GO:0032844 182 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
ion transmembrane transport GO:0034220 361 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
sequestering of calcium ion GO:0051208 18 0.016
nitrogen compound transport GO:0071705 271 0.016
cellular ion homeostasis GO:0006873 165 0.016
organ growth GO:0035265 117 0.016
regulation of intracellular transport GO:0032386 159 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
endomembrane system organization GO:0010256 147 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
regulation of hormone levels GO:0010817 211 0.016
positive regulation of cell development GO:0010720 237 0.016
Fly
regulation of cell migration GO:0030334 219 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of innate immune response GO:0045088 91 0.016
cell substrate adhesion GO:0031589 130 0.016
regulation of cell motility GO:2000145 236 0.016
regulation of cell cycle GO:0051726 281 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
Mouse
single organismal cell cell adhesion GO:0016337 131 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
compound eye development GO:0048749 1 0.015
Fly
sequestering of metal ion GO:0051238 19 0.015
response to organic cyclic compound GO:0014070 198 0.015
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.015
positive regulation of cell death GO:0010942 224 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
sensory perception GO:0007600 245 0.015
cellular chemical homeostasis GO:0055082 215 0.015
glucose homeostasis GO:0042593 128 0.015
metal ion homeostasis GO:0055065 189 0.015
circulatory system process GO:0003013 197 0.015
positive regulation of kinase activity GO:0033674 155 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
carbohydrate metabolic process GO:0005975 230 0.015
nuclear transport GO:0051169 139 0.015
myosin filament assembly GO:0031034 2 0.015
positive regulation of secretion GO:0051047 130 0.015
spermatogenesis GO:0007283 284 0.015
mesodermal cell migration GO:0008078 4 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
Fly
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
Fly
negative regulation of protein modification process GO:0031400 163 0.015
Fly
response to acid chemical GO:0001101 111 0.015
myosin filament organization GO:0031033 3 0.015
blood vessel morphogenesis GO:0048514 285 0.015
nuclear division GO:0000280 158 0.015
regulation of cellular component size GO:0032535 121 0.015
Mouse
protein modification by small protein conjugation GO:0032446 187 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.014
Fly
establishment of protein localization to organelle GO:0072594 118 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
response to inorganic substance GO:0010035 96 0.014
cellular response to lipid GO:0071396 145 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
positive regulation of rho gtpase activity GO:0032321 41 0.014
interleukin 8 production GO:0032637 4 0.014
regulation of protein kinase activity GO:0045859 232 0.014
Fly
rab protein signal transduction GO:0032482 1 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of anatomical structure size GO:0090066 178 0.014
Mouse
striated muscle tissue development GO:0014706 293 0.014
skeletal muscle organ development GO:0060538 163 0.014
rac protein signal transduction GO:0016601 13 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
myeloid leukocyte activation GO:0002274 83 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
Fly
organonitrogen compound biosynthetic process GO:1901566 192 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
t cell differentiation GO:0030217 174 0.014
negative regulation of cell activation GO:0050866 111 0.014
negative regulation of defense response GO:0031348 77 0.014
ossification GO:0001503 216 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of protein transport GO:0051223 163 0.014
regulation of neuron projection development GO:0010975 169 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
cellular response to dna damage stimulus GO:0006974 207 0.013
actin filament polymerization GO:0030041 44 0.013
Yeast Mouse
myeloid cell differentiation GO:0030099 233 0.013
regulation of adaptive immune response GO:0002819 90 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
lateral inhibition GO:0046331 1 0.013
cardiac muscle tissue development GO:0048738 130 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
multi multicellular organism process GO:0044706 109 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
muscle cell differentiation GO:0042692 261 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
anion transport GO:0006820 177 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
dephosphorylation GO:0016311 129 0.013
glycoprotein metabolic process GO:0009100 116 0.013
negative regulation of protein maturation GO:1903318 79 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
Yeast Mouse
reactive oxygen species metabolic process GO:0072593 84 0.013
antigen receptor mediated signaling pathway GO:0050851 64 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
peptidyl serine modification GO:0018209 83 0.013
protein ubiquitination GO:0016567 171 0.013
camera type eye development GO:0043010 266 0.013
sulfur compound metabolic process GO:0006790 100 0.012
anatomical structure homeostasis GO:0060249 145 0.012
small molecule biosynthetic process GO:0044283 132 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
lipid biosynthetic process GO:0008610 179 0.012
organelle fission GO:0048285 170 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
microtubule based process GO:0007017 236 0.012
regulation of b cell activation GO:0050864 81 0.012
regulation of vasculature development GO:1901342 88 0.012
multicellular organism growth GO:0035264 161 0.012
germ cell development GO:0007281 185 0.012
meiotic cell cycle GO:0051321 122 0.012
plasma membrane organization GO:0007009 90 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
Fly
striated muscle myosin thick filament assembly GO:0071688 1 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
regulation of proteolysis GO:0030162 164 0.012
developmental maturation GO:0021700 193 0.012
regulation of neuron differentiation GO:0045664 281 0.012
Fly
cellular response to hormone stimulus GO:0032870 150 0.012
regulation of cellular response to stress GO:0080135 159 0.012
cell recognition GO:0008037 83 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
Fly
regulation of lymphocyte proliferation GO:0050670 117 0.012
ameboidal type cell migration GO:0001667 128 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
positive regulation of cell activation GO:0050867 158 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
positive regulation of cell migration GO:0030335 109 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
regulation of response to wounding GO:1903034 189 0.012
positive regulation of nervous system development GO:0051962 221 0.012
Fly
regulation of epithelial cell proliferation GO:0050678 141 0.012
defense response to bacterium GO:0042742 119 0.011
b cell differentiation GO:0030183 78 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
Mouse Fly
positive regulation of interleukin 8 production GO:0032757 2 0.011
spermatid differentiation GO:0048515 115 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
meiotic nuclear division GO:0007126 115 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
regulation of angiogenesis GO:0045765 81 0.011
actin filament organization GO:0007015 113 0.011
Yeast Mouse Fly
locomotory behavior GO:0007626 195 0.011
regulation of system process GO:0044057 200 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
regulation of protein targeting GO:1903533 61 0.011
fertilization GO:0009566 127 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
telencephalon development GO:0021537 186 0.011
synapse organization GO:0050808 125 0.011
protein localization to nucleus GO:0034504 121 0.011
protein import GO:0017038 101 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
muscle system process GO:0003012 141 0.011
epithelial cell development GO:0002064 159 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
Mouse
regulation of protein catabolic process GO:0042176 108 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
calcium ion homeostasis GO:0055074 127 0.011
exocytosis GO:0006887 121 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
Mouse
negative regulation of cell development GO:0010721 169 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
response to extracellular stimulus GO:0009991 127 0.010
forebrain development GO:0030900 302 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
protein polymerization GO:0051258 57 0.010
Yeast Mouse
mitotic cell cycle GO:0000278 195 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
nuclear import GO:0051170 95 0.010
positive regulation of organelle organization GO:0010638 128 0.010
Mouse
spermatid development GO:0007286 108 0.010
regulation of protein maturation GO:1903317 96 0.010
response to growth factor GO:0070848 198 0.010
Mouse
regulation of production of molecular mediator of immune response GO:0002700 65 0.010
cytokinetic process GO:0032506 2 0.010
response to oxidative stress GO:0006979 123 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
leukocyte homeostasis GO:0001776 79 0.010
positive regulation of adaptive immune response GO:0002821 61 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
digestive system development GO:0055123 200 0.010
chromatin organization GO:0006325 206 0.010
extracellular matrix organization GO:0030198 147 0.010

Grap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.023
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.011