Mus musculus

39 known processes

Fbxw4

F-box and WD-40 domain protein 4

(Aliases: SHFM3,SHSF3,Fbw4,Dac,dactylyn,dactylin)

Fbxw4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 166 0.424
cellular lipid metabolic process GO:0044255 323 0.190
regulation of cellular ketone metabolic process GO:0010565 66 0.115
carbohydrate metabolic process GO:0005975 230 0.108
cellular amine metabolic process GO:0044106 44 0.091
aromatic compound catabolic process GO:0019439 286 0.088
nucleoside phosphate metabolic process GO:0006753 338 0.086
cellular nitrogen compound catabolic process GO:0044270 280 0.085
cellular ketone metabolic process GO:0042180 84 0.081
ras protein signal transduction GO:0007265 77 0.079
organic cyclic compound catabolic process GO:1901361 295 0.074
nucleotide metabolic process GO:0009117 332 0.072
regulation of cellular catabolic process GO:0031329 242 0.069
purine containing compound metabolic process GO:0072521 311 0.068
heterocycle catabolic process GO:0046700 280 0.064
nucleobase containing small molecule metabolic process GO:0055086 352 0.063
transmembrane transport GO:0055085 412 0.061
glycosyl compound catabolic process GO:1901658 206 0.060
carbohydrate derivative catabolic process GO:1901136 231 0.060
oxidation reduction process GO:0055114 342 0.059
negative regulation of phosphorus metabolic process GO:0010563 184 0.059
nucleotide catabolic process GO:0009166 217 0.058
nitrogen compound transport GO:0071705 271 0.058
purine nucleotide metabolic process GO:0006163 302 0.057
ion transmembrane transport GO:0034220 361 0.055
ribose phosphate metabolic process GO:0019693 291 0.055
nucleoside phosphate catabolic process GO:1901292 222 0.054
ribonucleotide catabolic process GO:0009261 208 0.054
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.053
organonitrogen compound catabolic process GO:1901565 264 0.052
positive regulation of protein phosphorylation GO:0001934 242 0.050
fatty acid metabolic process GO:0006631 121 0.050
inorganic cation transmembrane transport GO:0098662 207 0.050
nucleoside catabolic process GO:0009164 206 0.050
purine nucleoside catabolic process GO:0006152 205 0.050
ribonucleotide metabolic process GO:0009259 291 0.050
regionalization GO:0003002 337 0.049
positive regulation of cellular amine metabolic process GO:0033240 5 0.048
purine ribonucleoside metabolic process GO:0046128 241 0.047
purine containing compound catabolic process GO:0072523 213 0.047
purine ribonucleotide metabolic process GO:0009150 290 0.047
glycosyl compound metabolic process GO:1901657 246 0.045
regulation of secretion by cell GO:1903530 249 0.044
inorganic ion transmembrane transport GO:0098660 234 0.043
regulation of ras protein signal transduction GO:0046578 114 0.043
organophosphate catabolic process GO:0046434 232 0.041
nucleoside metabolic process GO:0009116 246 0.041
cation transmembrane transport GO:0098655 266 0.040
ribonucleoside catabolic process GO:0042454 206 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
carbohydrate derivative biosynthetic process GO:1901137 183 0.039
cation transport GO:0006812 399 0.039
negative regulation of cell proliferation GO:0008285 296 0.038
purine ribonucleotide catabolic process GO:0009154 208 0.038
protein modification by small protein conjugation or removal GO:0070647 207 0.038
connective tissue development GO:0061448 179 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
positive regulation of protein modification process GO:0031401 299 0.037
nucleoside triphosphate catabolic process GO:0009143 205 0.036
membrane organization GO:0061024 245 0.036
ribonucleoside triphosphate catabolic process GO:0009203 199 0.035
protein glycosylation GO:0006486 55 0.035
amine metabolic process GO:0009308 45 0.035
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
response to peptide GO:1901652 136 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.032
maintenance of location GO:0051235 89 0.032
compound eye development GO:0048749 1 0.032
purine nucleotide catabolic process GO:0006195 211 0.032
skeletal system development GO:0001501 356 0.032
protein modification by small protein conjugation GO:0032446 187 0.031
cellular amino acid metabolic process GO:0006520 103 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
muscle tissue development GO:0060537 308 0.031
purine ribonucleoside catabolic process GO:0046130 205 0.030
regulation of secretion GO:0051046 274 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
regulation of nucleoside metabolic process GO:0009118 130 0.030
macromolecule glycosylation GO:0043413 55 0.030
protein catabolic process GO:0030163 221 0.030
inflammatory response GO:0006954 244 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
protein ubiquitination GO:0016567 171 0.029
rhythmic process GO:0048511 174 0.029
regulation of system process GO:0044057 200 0.028
cellular response to lipid GO:0071396 145 0.028
heart contraction GO:0060047 93 0.028
cellular response to peptide GO:1901653 92 0.028
muscle cell differentiation GO:0042692 261 0.028
muscle system process GO:0003012 141 0.028
regulation of purine nucleotide catabolic process GO:0033121 122 0.028
microtubule based process GO:0007017 236 0.027
regulation of cell cycle GO:0051726 281 0.027
macromolecule catabolic process GO:0009057 281 0.027
regulation of kinase activity GO:0043549 249 0.027
regulation of neuron differentiation GO:0045664 281 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
regulation of hydrolase activity GO:0051336 246 0.027
striated muscle tissue development GO:0014706 293 0.027
mitotic cell cycle GO:0000278 195 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
blood vessel morphogenesis GO:0048514 285 0.026
positive regulation of apoptotic process GO:0043065 217 0.026
response to molecule of bacterial origin GO:0002237 143 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
organic acid biosynthetic process GO:0016053 86 0.026
positive regulation of cell death GO:0010942 224 0.026
protein localization to organelle GO:0033365 185 0.026
regulation of transferase activity GO:0051338 263 0.025
regulation of nucleotide catabolic process GO:0030811 122 0.025
apoptotic signaling pathway GO:0097190 306 0.025
regulation of mapk cascade GO:0043408 248 0.025
glucose homeostasis GO:0042593 128 0.025
cell type specific apoptotic process GO:0097285 268 0.024
positive regulation of cellular catabolic process GO:0031331 148 0.024
lipid biosynthetic process GO:0008610 179 0.024
skeletal muscle organ development GO:0060538 163 0.024
leukocyte differentiation GO:0002521 342 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
blood circulation GO:0008015 195 0.024
gland development GO:0048732 330 0.023
sensory perception GO:0007600 245 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
glycosylation GO:0070085 62 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
peptidyl amino acid modification GO:0018193 336 0.023
glycoprotein metabolic process GO:0009100 116 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
regulation of response to wounding GO:1903034 189 0.023
lung development GO:0030324 164 0.023
anion transport GO:0006820 177 0.023
mapk cascade GO:0000165 281 0.023
glycoprotein biosynthetic process GO:0009101 89 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
protein maturation GO:0051604 176 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
regulation of organelle organization GO:0033043 289 0.022
positive regulation of organelle organization GO:0010638 128 0.022
regulation of cytokine production GO:0001817 266 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
tube formation GO:0035148 140 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.021
cellular protein catabolic process GO:0044257 155 0.021
cytokine production GO:0001816 319 0.021
response to organonitrogen compound GO:0010243 246 0.021
lipid localization GO:0010876 126 0.021
chromatin organization GO:0006325 206 0.021
divalent inorganic cation transport GO:0072511 178 0.021
positive regulation of cell development GO:0010720 237 0.020
response to acid chemical GO:0001101 111 0.020
cellular response to acid chemical GO:0071229 68 0.020
regulation of cell activation GO:0050865 289 0.020
gtp catabolic process GO:0006184 143 0.020
wnt signaling pathway GO:0016055 188 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
gtp metabolic process GO:0046039 144 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
extracellular matrix organization GO:0030198 147 0.019
organelle fission GO:0048285 170 0.019
skin development GO:0043588 220 0.019
cellular homeostasis GO:0019725 240 0.019
dna metabolic process GO:0006259 303 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
divalent metal ion transport GO:0070838 172 0.019
positive regulation of gtpase activity GO:0043547 85 0.019
cell division GO:0051301 120 0.019
regulation of cell projection organization GO:0031344 206 0.019
response to peptide hormone GO:0043434 127 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
spermatogenesis GO:0007283 284 0.019
establishment of protein localization to organelle GO:0072594 118 0.018
locomotory behavior GO:0007626 195 0.018
rab protein signal transduction GO:0032482 1 0.018
cellular response to peptide hormone stimulus GO:0071375 92 0.018
extracellular structure organization GO:0043062 148 0.018
nuclear division GO:0000280 158 0.018
interleukin 8 production GO:0032637 4 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
wound healing GO:0042060 157 0.018
regulation of body fluid levels GO:0050878 162 0.018
stem cell differentiation GO:0048863 268 0.018
regulation of cellular response to stress GO:0080135 159 0.017
negative regulation of protein modification process GO:0031400 163 0.017
fat cell differentiation GO:0045444 160 0.017
fertilization GO:0009566 127 0.017
regulation of protein transport GO:0051223 163 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
heart morphogenesis GO:0003007 178 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
monosaccharide metabolic process GO:0005996 106 0.017
small molecule biosynthetic process GO:0044283 132 0.017
carbohydrate homeostasis GO:0033500 128 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
regulation of membrane potential GO:0042391 192 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
digestive system development GO:0055123 200 0.017
regulation of gtp catabolic process GO:0033124 113 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
dephosphorylation GO:0016311 129 0.017
cellular chemical homeostasis GO:0055082 215 0.017
peptide transport GO:0015833 133 0.017
neural tube formation GO:0001841 108 0.016
male gamete generation GO:0048232 285 0.016
response to insulin GO:0032868 100 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
positive regulation of proteolysis GO:0045862 85 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
negative regulation of nervous system development GO:0051961 156 0.016
regulation of protein kinase activity GO:0045859 232 0.016
regulation of neuron death GO:1901214 134 0.016
chromatin modification GO:0016568 187 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
calcium ion transport GO:0006816 159 0.016
plasma membrane organization GO:0007009 90 0.016
hexose metabolic process GO:0019318 98 0.016
negative regulation of molecular function GO:0044092 258 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
circadian rhythm GO:0007623 114 0.016
lateral inhibition GO:0046331 1 0.016
cellular response to nutrient levels GO:0031669 64 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
regulation of cell adhesion GO:0030155 154 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
fatty acid transmembrane transport GO:1902001 1 0.015
protein processing GO:0016485 163 0.015
regulation of homeostatic process GO:0032844 182 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
respiratory system development GO:0060541 190 0.015
regulation of feeding behavior GO:0060259 3 0.015
placenta development GO:0001890 140 0.015
epithelial cell proliferation GO:0050673 174 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
learning or memory GO:0007611 148 0.015
glucose metabolic process GO:0006006 92 0.015
epithelial tube formation GO:0072175 130 0.015
response to lipopolysaccharide GO:0032496 128 0.015
positive regulation of gtp catabolic process GO:0033126 85 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
dna repair GO:0006281 107 0.014
response to inorganic substance GO:0010035 96 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
cardiac muscle contraction GO:0060048 32 0.014
myotube differentiation GO:0014902 105 0.014
intracellular protein transport GO:0006886 204 0.014
ossification GO:0001503 216 0.014
action potential GO:0001508 78 0.014
lipid transport GO:0006869 98 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
neural tube development GO:0021915 160 0.014
rho protein signal transduction GO:0007266 32 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
lymphocyte differentiation GO:0030098 242 0.014
very long chain fatty acid catabolic process GO:0042760 2 0.014
negative regulation of cell development GO:0010721 169 0.014
regulation of protein localization GO:0032880 231 0.014
polysaccharide metabolic process GO:0005976 39 0.014
t cell activation GO:0042110 289 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
cation homeostasis GO:0055080 212 0.014
neural precursor cell proliferation GO:0061351 121 0.014
cognition GO:0050890 149 0.014
regulation of defense response GO:0031347 233 0.014
response to extracellular stimulus GO:0009991 127 0.013
forebrain development GO:0030900 302 0.013
multicellular organism growth GO:0035264 161 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
positive regulation of nervous system development GO:0051962 221 0.013
regulation of proteolysis GO:0030162 164 0.013
urogenital system development GO:0001655 261 0.013
immune effector process GO:0002252 321 0.013
muscle cell development GO:0055001 133 0.013
sensory organ morphogenesis GO:0090596 242 0.013
anatomical structure homeostasis GO:0060249 145 0.013
negative regulation of cytokine production GO:0001818 84 0.013
regulation of ion transport GO:0043269 215 0.013
regulation of hormone levels GO:0010817 211 0.013
lipid homeostasis GO:0055088 63 0.013
heart process GO:0003015 94 0.013
regulation of protein secretion GO:0050708 82 0.013
positive regulation of kinase activity GO:0033674 155 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
regulation of transmembrane transport GO:0034762 128 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
development of primary sexual characteristics GO:0045137 143 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
neuron apoptotic process GO:0051402 142 0.012
regulation of cell cycle process GO:0010564 160 0.012
chemotaxis GO:0006935 247 0.012
amide transport GO:0042886 138 0.012
regulation of inflammatory response GO:0050727 147 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
regulation of circadian rhythm GO:0042752 58 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
actin cytoskeleton organization GO:0030036 220 0.012
carbon catabolite activation of transcription GO:0045991 4 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
negative regulation of growth GO:0045926 99 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
response to organic cyclic compound GO:0014070 198 0.012
peptide hormone secretion GO:0030072 109 0.012
translation GO:0006412 93 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
positive regulation of transferase activity GO:0051347 167 0.012
regulation of peptide transport GO:0090087 91 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
lipoprotein metabolic process GO:0042157 43 0.012
response to radiation GO:0009314 165 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
ear development GO:0043583 200 0.012
cellular glucan metabolic process GO:0006073 32 0.011
regulation of ossification GO:0030278 112 0.011
stem cell proliferation GO:0072089 117 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
b cell activation GO:0042113 161 0.011
circulatory system process GO:0003013 197 0.011
positive regulation of fatty acid oxidation GO:0046321 4 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
regulation of hormone secretion GO:0046883 88 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
negative regulation of wnt signaling pathway GO:0030178 73 0.011
metal ion homeostasis GO:0055065 189 0.011
regulation of protein catabolic process GO:0042176 108 0.011
gastrulation GO:0007369 116 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
localization within membrane GO:0051668 4 0.011
regulation of fatty acid metabolic process GO:0019217 28 0.011
organic anion transport GO:0015711 137 0.011
carboxylic acid transport GO:0046942 100 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
leukocyte migration GO:0050900 124 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
acetylcholine transport GO:0015870 2 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
response to oxidative stress GO:0006979 123 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
innate immune response GO:0045087 157 0.011
female sex differentiation GO:0046660 84 0.011
regulation of neuron projection development GO:0010975 169 0.011
axon ensheathment GO:0008366 76 0.011
neuron death GO:0070997 154 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
negative regulation of immune system process GO:0002683 209 0.011
hormone secretion GO:0046879 128 0.011
stem cell maintenance GO:0019827 130 0.011
mitotic cell cycle process GO:1903047 159 0.011
somitogenesis GO:0001756 69 0.011
carbon catabolite regulation of transcription GO:0045990 4 0.011
positive regulation of homeostatic process GO:0032846 64 0.011
lipid modification GO:0030258 65 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
monocarboxylic acid transport GO:0015718 44 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
skeletal system morphogenesis GO:0048705 203 0.011
cellular polysaccharide metabolic process GO:0044264 38 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
protein targeting GO:0006605 143 0.010
digestive tract development GO:0048565 190 0.010
peptidyl serine modification GO:0018209 83 0.010
positive regulation of secretion GO:0051047 130 0.010
response to light stimulus GO:0009416 135 0.010
regulation of embryonic development GO:0045995 71 0.010
multi multicellular organism process GO:0044706 109 0.010
cell substrate adhesion GO:0031589 130 0.010
regulation of t cell activation GO:0050863 170 0.010
mesoderm development GO:0007498 100 0.010
peptide secretion GO:0002790 114 0.010
amino sugar catabolic process GO:0046348 1 0.010
lytic vacuole organization GO:0080171 21 0.010
regulation of translation GO:0006417 71 0.010
response to transforming growth factor beta GO:0071559 88 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
limb development GO:0060173 166 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
steroid metabolic process GO:0008202 119 0.010
regulation of multi organism process GO:0043900 111 0.010
stem cell development GO:0048864 219 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
phospholipid metabolic process GO:0006644 87 0.010
multicellular organismal signaling GO:0035637 91 0.010
asymmetric stem cell division GO:0098722 3 0.010

Fbxw4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
disease of metabolism DOID:0014667 0 0.019
central nervous system disease DOID:331 0 0.016
inherited metabolic disorder DOID:655 0 0.012
neurodegenerative disease DOID:1289 0 0.011
musculoskeletal system disease DOID:17 0 0.010