Mus musculus

143 known processes

Thrb

thyroid hormone receptor beta

(Aliases: Nr1a2,T3R[b],Thrb1,Thrb2,T3Rbeta,MGC141269,MGC141270,c-erbAbeta)

Thrb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of mechanical stimulus GO:0050954 107 0.999
sensory perception of sound GO:0007605 97 0.999
sensory organ morphogenesis GO:0090596 242 0.995
Zebrafish Mouse
detection of external stimulus GO:0009581 61 0.993
inorganic anion transport GO:0015698 43 0.991
cellular modified amino acid metabolic process GO:0006575 63 0.991
organic hydroxy compound metabolic process GO:1901615 203 0.990
Mouse Rat
detection of stimulus GO:0051606 84 0.989
embryonic organ morphogenesis GO:0048562 276 0.986
Mouse
regulation of feeding behavior GO:0060259 3 0.983
anion transmembrane transport GO:0098656 71 0.983
inorganic anion transmembrane transport GO:0098661 29 0.979
gland development GO:0048732 330 0.978
Mouse
ear development GO:0043583 200 0.975
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.974
ion transmembrane transport GO:0034220 361 0.974
cellular amino acid metabolic process GO:0006520 103 0.971
cellular homeostasis GO:0019725 240 0.969
Mouse
phenol containing compound metabolic process GO:0018958 60 0.968
male gamete generation GO:0048232 285 0.967
Mouse
organic acid transport GO:0015849 101 0.964
sensory perception GO:0007600 245 0.963
regulation of system process GO:0044057 200 0.958
regulation of secretion by cell GO:1903530 249 0.956
Mouse
reflex GO:0060004 22 0.949
chloride transmembrane transport GO:1902476 24 0.949
cytokine production GO:0001816 319 0.947
mechanoreceptor differentiation GO:0042490 67 0.946
blood circulation GO:0008015 195 0.944
regulation of secretion GO:0051046 274 0.943
Mouse
inner ear receptor cell development GO:0060119 39 0.941
circulatory system process GO:0003013 197 0.940
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.939
amide transport GO:0042886 138 0.939
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.934
Human Zebrafish Mouse Rat
multicellular organism growth GO:0035264 161 0.932
Mouse
regulation of membrane potential GO:0042391 192 0.930
synaptic transmission GO:0007268 329 0.928
thyroid hormone metabolic process GO:0042403 16 0.914
response to radiation GO:0009314 165 0.913
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.910
g protein coupled receptor signaling pathway GO:0007186 243 0.910
hormone secretion GO:0046879 128 0.909
Mouse
peptide secretion GO:0002790 114 0.907
Mouse
cellular metal ion homeostasis GO:0006875 151 0.901
acetylcholine transport GO:0015870 2 0.900
detection of abiotic stimulus GO:0009582 60 0.898
acetylcholine secretion neurotransmission GO:0014055 2 0.893
gamma aminobutyric acid signaling pathway GO:0007214 8 0.889
negative regulation of cell proliferation GO:0008285 296 0.888
Mouse
cellular chemical homeostasis GO:0055082 215 0.883
Mouse
inner ear receptor cell differentiation GO:0060113 61 0.875
transepithelial chloride transport GO:0030321 4 0.867
organic hydroxy compound biosynthetic process GO:1901617 77 0.862
Mouse
anion transport GO:0006820 177 0.856
cellular ion homeostasis GO:0006873 165 0.855
amino acid transport GO:0006865 61 0.853
regulation of hormone secretion GO:0046883 88 0.851
Mouse
regulation of steroid metabolic process GO:0019218 39 0.847
Mouse Rat
action potential GO:0001508 78 0.846
regulation of steroid biosynthetic process GO:0050810 26 0.846
Mouse
regulation of homeostatic process GO:0032844 182 0.841
Mouse
epithelial tube morphogenesis GO:0060562 303 0.823
Mouse
carboxylic acid transport GO:0046942 100 0.822
organic anion transport GO:0015711 137 0.807
multicellular organismal homeostasis GO:0048871 164 0.800
Mouse
ear morphogenesis GO:0042471 118 0.799
response to monosaccharide GO:0034284 67 0.780
Mouse
response to drug GO:0042493 75 0.777
response to light stimulus GO:0009416 135 0.777
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.774
regulation of peptide secretion GO:0002791 77 0.770
Mouse
cation transmembrane transport GO:0098655 266 0.769
central nervous system neuron differentiation GO:0021953 162 0.766
learning or memory GO:0007611 148 0.761
Mouse
hormone metabolic process GO:0042445 86 0.760
renal system process GO:0003014 48 0.758
monocarboxylic acid metabolic process GO:0032787 191 0.758
Mouse
organ growth GO:0035265 117 0.751
Mouse
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.743
negative regulation of hormone metabolic process GO:0032351 4 0.738
detection of stimulus involved in sensory perception GO:0050906 44 0.726
transmission of nerve impulse GO:0019226 76 0.724
germ cell development GO:0007281 185 0.720
Mouse
sperm capacitation GO:0048240 17 0.707
small molecule biosynthetic process GO:0044283 132 0.702
Mouse
activation of immune response GO:0002253 138 0.699
cellular response to monosaccharide stimulus GO:0071326 47 0.697
Mouse
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.695
carbohydrate transport GO:0008643 62 0.695
multicellular organismal signaling GO:0035637 91 0.692
peptide transport GO:0015833 133 0.692
Mouse
negative regulation of histone h3 k9 methylation GO:0051573 4 0.691
developmental maturation GO:0021700 193 0.686
energy derivation by oxidation of organic compounds GO:0015980 77 0.677
Mouse
regulation of blood circulation GO:1903522 93 0.675
regulation of inflammatory response GO:0050727 147 0.665
Mouse
steroid metabolic process GO:0008202 119 0.664
Mouse Rat
response to organic cyclic compound GO:0014070 198 0.658
positive regulation of steroid biosynthetic process GO:0010893 4 0.657
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.656
fluid transport GO:0042044 14 0.653
regulation of hormone levels GO:0010817 211 0.647
Mouse
cation homeostasis GO:0055080 212 0.640
positive regulation of apoptotic process GO:0043065 217 0.636
Mouse
sulfur compound metabolic process GO:0006790 100 0.633
negative regulation of protein metabolic process GO:0051248 282 0.627
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.622
Mouse
response to organonitrogen compound GO:0010243 246 0.618
detection of visible light GO:0009584 14 0.610
regulation of response to wounding GO:1903034 189 0.608
Mouse
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.601
cellular divalent inorganic cation homeostasis GO:0072503 127 0.598
wnt signaling pathway involved in kidney development GO:0061289 2 0.595
cation transport GO:0006812 399 0.595
cellular response to carbohydrate stimulus GO:0071322 50 0.591
Mouse
metal ion homeostasis GO:0055065 189 0.587
rhythmic process GO:0048511 174 0.584
Mouse
cellular polysaccharide metabolic process GO:0044264 38 0.581
Mouse
negative regulation of transferase activity GO:0051348 85 0.576
regulation of glucose metabolic process GO:0010906 60 0.572
circadian temperature homeostasis GO:0060086 2 0.570
Mouse
calcium ion transmembrane transport GO:0070588 85 0.568
peptide hormone secretion GO:0030072 109 0.566
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.555
glandular epithelial cell differentiation GO:0002067 38 0.551
Mouse
regulation of lipid biosynthetic process GO:0046890 54 0.543
Mouse
positive regulation of dipeptide transmembrane transport GO:2001150 2 0.541
positive regulation of growth GO:0045927 104 0.536
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.529
positive regulation of glycolytic process GO:0045821 4 0.523
chloride transport GO:0006821 32 0.523
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.523
adult behavior GO:0030534 135 0.523
cytosolic calcium ion homeostasis GO:0051480 70 0.513
detection of mechanical stimulus GO:0050982 27 0.513
amine metabolic process GO:0009308 45 0.504
tissue homeostasis GO:0001894 115 0.501
forebrain development GO:0030900 302 0.500
Mouse
regulation of ph GO:0006885 26 0.500
camp metabolic process GO:0046058 40 0.492
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.488
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.488
response to nutrient levels GO:0031667 109 0.484
insulin secretion GO:0030073 89 0.482
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.481
response to retinoic acid GO:0032526 56 0.479
Mouse
transmembrane transport GO:0055085 412 0.477
organic hydroxy compound transport GO:0015850 93 0.476
lactation GO:0007595 25 0.466
regulation of carbohydrate metabolic process GO:0006109 75 0.465
determination of left right symmetry GO:0007368 80 0.462
regulation of cytokine production GO:0001817 266 0.459
heart process GO:0003015 94 0.458
potassium ion transmembrane transport GO:0071805 43 0.457
hypophysis morphogenesis GO:0048850 3 0.456
carbohydrate metabolic process GO:0005975 230 0.449
Mouse
cellular response to abiotic stimulus GO:0071214 56 0.443
reactive oxygen species metabolic process GO:0072593 84 0.442
endocrine system development GO:0035270 98 0.441
Mouse
retinal cone cell differentiation GO:0042670 8 0.438
Zebrafish
ossification GO:0001503 216 0.434
Mouse Rat
membrane hyperpolarization GO:0060081 21 0.434
regulation of body fluid levels GO:0050878 162 0.432
alcohol metabolic process GO:0006066 116 0.429
Rat
adult locomotory behavior GO:0008344 91 0.425
negative regulation of neuron death GO:1901215 98 0.424
sensory perception of light stimulus GO:0050953 54 0.421
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.420
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.418
organic acid catabolic process GO:0016054 51 0.415
wound healing GO:0042060 157 0.414
cognition GO:0050890 149 0.413
Mouse
cellular response to hormone stimulus GO:0032870 150 0.411
Mouse
cyclic nucleotide metabolic process GO:0009187 59 0.410
heart contraction GO:0060047 93 0.406
reproductive behavior GO:0019098 32 0.403
retinal cone cell development GO:0046549 8 0.401
Zebrafish
fertilization GO:0009566 127 0.399
circadian rhythm GO:0007623 114 0.397
Mouse
nitrogen compound transport GO:0071705 271 0.396
Mouse
inner ear morphogenesis GO:0042472 101 0.396
regulation of neurotransmitter secretion GO:0046928 29 0.392
cellular response to hexose stimulus GO:0071331 47 0.391
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.390
regulation of blood pressure GO:0008217 93 0.387
glucose metabolic process GO:0006006 92 0.387
type i pneumocyte differentiation GO:0060509 7 0.382
regulation of cell motility GO:2000145 236 0.381
calcium ion dependent exocytosis GO:0017156 35 0.380
prostate gland development GO:0030850 48 0.380
Mouse
oligopeptide transmembrane transport GO:0035672 4 0.378
response to extracellular stimulus GO:0009991 127 0.374
regulation of cellular ketone metabolic process GO:0010565 66 0.374
Mouse
inner ear receptor stereocilium organization GO:0060122 23 0.374
ensheathment of neurons GO:0007272 76 0.371
establishment of protein localization to organelle GO:0072594 118 0.368
Mouse
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.362
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.356
regulation of hormone metabolic process GO:0032350 15 0.353
regulation of purine nucleotide metabolic process GO:1900542 169 0.349
positive regulation of camp metabolic process GO:0030816 19 0.349
blood coagulation GO:0007596 76 0.348
cerebellar purkinje cell differentiation GO:0021702 13 0.348
monosaccharide metabolic process GO:0005996 106 0.346
response to acid chemical GO:0001101 111 0.343
Mouse
musculoskeletal movement spinal reflex action GO:0050883 3 0.343
monocarboxylic acid transport GO:0015718 44 0.340
membrane repolarization GO:0086009 7 0.340
coagulation GO:0050817 78 0.338
spermatid differentiation GO:0048515 115 0.337
digestion GO:0007586 40 0.337
cell growth GO:0016049 130 0.336
Mouse
carbohydrate homeostasis GO:0033500 128 0.335
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.335
optic nerve structural organization GO:0021633 2 0.332
cellular carbohydrate metabolic process GO:0044262 119 0.330
Mouse
lipid biosynthetic process GO:0008610 179 0.330
Mouse
extraocular skeletal muscle development GO:0002074 2 0.328
oxidation reduction process GO:0055114 342 0.326
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.325
camera type eye development GO:0043010 266 0.325
Zebrafish Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.324
regulation of peptide transport GO:0090087 91 0.324
Mouse
regulation of response to drug GO:2001023 2 0.322
regulation of protein localization GO:0032880 231 0.318
Mouse
small molecule catabolic process GO:0044282 71 0.318
camp biosynthetic process GO:0006171 31 0.315
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.313
second messenger mediated signaling GO:0019932 73 0.309
positive regulation of cellular amine metabolic process GO:0033240 5 0.302
carbohydrate biosynthetic process GO:0016051 74 0.302
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.300
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.296
eye photoreceptor cell differentiation GO:0001754 41 0.295
Zebrafish
positive regulation of programmed cell death GO:0043068 218 0.295
Mouse
skeletal system morphogenesis GO:0048705 203 0.294
Mouse
locomotory behavior GO:0007626 195 0.294
thyroid hormone mediated signaling pathway GO:0002154 3 0.293
Mouse
cyclic purine nucleotide metabolic process GO:0052652 43 0.293
spermatid development GO:0007286 108 0.290
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.289
Mouse
female mating behavior GO:0060180 8 0.289
gastric acid secretion GO:0001696 6 0.284
auditory receptor cell morphogenesis GO:0002093 15 0.283
vestibular nucleus development GO:0021750 2 0.283
maintenance of location GO:0051235 89 0.280
Mouse
sulfate transmembrane transport GO:1902358 3 0.279
epithelial cell proliferation GO:0050673 174 0.275
glucose homeostasis GO:0042593 128 0.274
Mouse
regulation of muscle system process GO:0090257 80 0.271
regulation of circadian rhythm GO:0042752 58 0.270
Mouse
regionalization GO:0003002 337 0.269
Mouse
positive regulation of dipeptide transport GO:2000880 2 0.268
cellular response to glucose stimulus GO:0071333 45 0.267
Mouse
regulation of myeloid leukocyte differentiation GO:0002761 58 0.263
Mouse
regulation of renal sodium excretion GO:0035813 3 0.262
excretion GO:0007588 22 0.260
development of primary male sexual characteristics GO:0046546 88 0.257
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.257
regulation of amine transport GO:0051952 21 0.256
anatomical structure homeostasis GO:0060249 145 0.254
negative regulation of phosphate metabolic process GO:0045936 184 0.253
alcohol biosynthetic process GO:0046165 43 0.249
chondroblast differentiation GO:0060591 2 0.248
Mouse
epithelial fluid transport GO:0042045 1 0.248
cellular response to organonitrogen compound GO:0071417 145 0.248
response to temperature stimulus GO:0009266 55 0.247
Mouse
hormone mediated signaling pathway GO:0009755 23 0.247
Mouse
calcium ion homeostasis GO:0055074 127 0.246
bone mineralization GO:0030282 54 0.244
morphogenesis of a branching epithelium GO:0061138 193 0.240
smoothened signaling pathway GO:0007224 105 0.238
rhodopsin mediated signaling pathway GO:0016056 4 0.238
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.238
myotube differentiation GO:0014902 105 0.236
Mouse
cellular amine metabolic process GO:0044106 44 0.236
lung development GO:0030324 164 0.235
striated muscle tissue development GO:0014706 293 0.233
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.230
cellular response to lipid GO:0071396 145 0.229
Mouse
placenta development GO:0001890 140 0.227
regulation of peptide hormone secretion GO:0090276 75 0.227
Mouse
organic hydroxy compound catabolic process GO:1901616 25 0.226
skeletal system development GO:0001501 356 0.226
Mouse Rat
response to alcohol GO:0097305 48 0.225
dicarboxylic acid transport GO:0006835 29 0.224
positive regulation of lipid biosynthetic process GO:0046889 18 0.222
Mouse
inflammatory response GO:0006954 244 0.221
Mouse
associative learning GO:0008306 61 0.221
cerebellar cortex formation GO:0021697 22 0.220
acetate ester transport GO:1901374 2 0.219
phospholipid metabolic process GO:0006644 87 0.217
negative regulation of kinase activity GO:0033673 81 0.216
urogenital system development GO:0001655 261 0.216
Mouse
smooth muscle contraction GO:0006939 44 0.215
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.215
regulation of thyroid hormone generation GO:2000609 4 0.212
positive regulation of kinase activity GO:0033674 155 0.211
regulation of heart contraction GO:0008016 77 0.208
muscle contraction GO:0006936 101 0.208
steroid biosynthetic process GO:0006694 47 0.207
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.207
positive regulation of hormone metabolic process GO:0032352 3 0.207
organonitrogen compound catabolic process GO:1901565 264 0.207
cellular response to radiation GO:0071478 28 0.204
urinary bladder smooth muscle contraction GO:0014832 5 0.203
chondrocyte hypertrophy GO:0003415 4 0.202
Mouse
activation of adenylate cyclase activity GO:0007190 4 0.201
cellular response to gonadotropin stimulus GO:0071371 4 0.201
protein localization to organelle GO:0033365 185 0.198
Mouse
response to purine containing compound GO:0014074 28 0.198
negative regulation of phosphorus metabolic process GO:0010563 184 0.197
cellular potassium ion transport GO:0071804 43 0.197
regulation of organelle organization GO:0033043 289 0.195
divalent inorganic cation homeostasis GO:0072507 138 0.193
thermosensory behavior GO:0040040 1 0.192
positive regulation of mapk cascade GO:0043410 170 0.191
regulation of exocytosis GO:0017157 61 0.190
regulation of neurotransmitter levels GO:0001505 87 0.190
limb development GO:0060173 166 0.190
Mouse
insulin like growth factor receptor signaling pathway GO:0048009 21 0.190
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.190
regulation of transferase activity GO:0051338 263 0.190
prostate gland growth GO:0060736 13 0.189
potassium ion transport GO:0006813 52 0.189
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.187
reactive oxygen species biosynthetic process GO:1903409 8 0.183
angiogenesis GO:0001525 201 0.183
chondrocyte development GO:0002063 24 0.182
Mouse
bicarbonate transport GO:0015701 7 0.182
regulation of leukocyte differentiation GO:1902105 159 0.181
Mouse
embryonic placenta development GO:0001892 98 0.181
septum primum development GO:0003284 4 0.180
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.179
limb morphogenesis GO:0035108 149 0.179
Mouse
morphogenesis of a branching structure GO:0001763 203 0.178
biomineral tissue development GO:0031214 64 0.177
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.175
regulation of cellular amino acid metabolic process GO:0006521 5 0.175
regulation of protein transport GO:0051223 163 0.174
Mouse
cardiac chamber development GO:0003205 108 0.173
Mouse
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.171
response to lipopolysaccharide GO:0032496 128 0.171
Mouse
regulation of tube size GO:0035150 57 0.170
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.170
diencephalon development GO:0021536 63 0.169
positive regulation of camp biosynthetic process GO:0030819 19 0.169
cochlea development GO:0090102 35 0.168
regulation of multi organism process GO:0043900 111 0.168
ureteric bud development GO:0001657 94 0.168
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.168
positive regulation of carbohydrate metabolic process GO:0045913 30 0.167
cholesterol homeostasis GO:0042632 44 0.167
Mouse
ribonucleotide biosynthetic process GO:0009260 59 0.167
cellular response to fructose stimulus GO:0071332 2 0.165
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.164
liver development GO:0001889 66 0.164
leukocyte differentiation GO:0002521 342 0.160
Mouse
muscle adaptation GO:0043500 39 0.159
male sex differentiation GO:0046661 109 0.158
Mouse
intracellular ph elevation GO:0051454 3 0.158
negative regulation of intracellular protein transport GO:0090317 27 0.157
Mouse
response to organophosphorus GO:0046683 22 0.157
regulation of oligopeptide transport GO:0090088 2 0.157
alpha beta t cell differentiation GO:0046632 69 0.157
calcium ion transport GO:0006816 159 0.156
lacrimal gland development GO:0032808 5 0.156
Mouse
dopamine receptor signaling pathway GO:0007212 16 0.156
epithelial cell development GO:0002064 159 0.155
Mouse
hexose metabolic process GO:0019318 98 0.155
organophosphate biosynthetic process GO:0090407 122 0.154
cell cell signaling involved in kidney development GO:0060995 2 0.154
glutamate secretion GO:0014047 8 0.154
regulation of blood vessel size GO:0050880 56 0.154
renal system development GO:0072001 225 0.153
Mouse
positive regulation of renal sodium excretion GO:0035815 2 0.153
canonical wnt signaling pathway involved in metanephric kidney development GO:0061290 2 0.151
response to inorganic substance GO:0010035 96 0.151
muscle system process GO:0003012 141 0.151
visual learning GO:0008542 44 0.150
mitochondrion organization GO:0007005 134 0.149
dicarboxylic acid metabolic process GO:0043648 18 0.149
regulation of canonical wnt signaling pathway GO:0060828 82 0.149
regulation of systemic arterial blood pressure GO:0003073 61 0.148
platelet activation GO:0030168 40 0.148
cerebellar purkinje cell layer formation GO:0021694 13 0.147
carboxylic acid biosynthetic process GO:0046394 86 0.146
Mouse
medulla oblongata development GO:0021550 3 0.144
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.143
nucleotide metabolic process GO:0009117 332 0.142
glycogen metabolic process GO:0005977 32 0.141
Mouse
energy reserve metabolic process GO:0006112 39 0.140
Mouse
ventricular cardiac muscle cell differentiation GO:0055012 17 0.140
Mouse
vascular process in circulatory system GO:0003018 62 0.140
negative regulation of cellular component organization GO:0051129 194 0.138
cellular response to lipopolysaccharide GO:0071222 77 0.138
Mouse
cytoplasmic transport GO:0016482 234 0.138
Mouse
gonad development GO:0008406 141 0.138
Mouse
regulation of transmembrane transport GO:0034762 128 0.137
regulation of organ growth GO:0046620 61 0.137
sensory perception of umami taste GO:0050917 4 0.136
heart morphogenesis GO:0003007 178 0.135
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.134
regulation of reactive oxygen species metabolic process GO:2000377 40 0.134
negative regulation of cellular protein metabolic process GO:0032269 247 0.133
Mouse
gamma aminobutyric acid secretion GO:0014051 6 0.132
negative regulation of intracellular signal transduction GO:1902532 167 0.132
regulation of androgen receptor signaling pathway GO:0060765 3 0.131
cell type specific apoptotic process GO:0097285 268 0.131
Mouse
binding of sperm to zona pellucida GO:0007339 34 0.131
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.130
polysaccharide metabolic process GO:0005976 39 0.130
Mouse
prostate gland epithelium morphogenesis GO:0060740 31 0.129
Mouse
cell differentiation involved in embryonic placenta development GO:0060706 26 0.129
cell proliferation in hindbrain GO:0021534 10 0.129
purine containing compound biosynthetic process GO:0072522 70 0.128
protein lipid complex subunit organization GO:0071825 12 0.128
nucleocytoplasmic transport GO:0006913 139 0.128
Mouse
ribose phosphate metabolic process GO:0019693 291 0.128
g protein coupled receptor internalization GO:0002031 3 0.125
regulation of cellular ph GO:0030641 12 0.125
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.125
memory GO:0007613 58 0.124
endodermal cell fate determination GO:0007493 2 0.123
regulation of protein secretion GO:0050708 82 0.123
nucleoside phosphate biosynthetic process GO:1901293 79 0.122
proteasomal protein catabolic process GO:0010498 98 0.122
Mouse
regulation of dopamine secretion GO:0014059 9 0.122
maternal process involved in female pregnancy GO:0060135 32 0.122
retina morphogenesis in camera type eye GO:0060042 45 0.121
Zebrafish
photoreceptor cell differentiation GO:0046530 52 0.121
Zebrafish
regulation of mapk cascade GO:0043408 248 0.120
cellular glucose homeostasis GO:0001678 52 0.120
Mouse
prostate epithelial cord elongation GO:0060523 3 0.119
renal sodium excretion GO:0035812 3 0.119
fat cell differentiation GO:0045444 160 0.118
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.117
Mouse
organic acid biosynthetic process GO:0016053 86 0.117
Mouse
cellular glucan metabolic process GO:0006073 32 0.117
Mouse
respiratory tube development GO:0030323 167 0.117
spinal cord development GO:0021510 81 0.117
negative regulation of protein transport GO:0051224 46 0.117
Mouse
response to oxygen levels GO:0070482 62 0.116
hormone biosynthetic process GO:0042446 16 0.116
response to histamine GO:0034776 1 0.116
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.116
regulation of generation of precursor metabolites and energy GO:0043467 38 0.115
negative regulation of female receptivity GO:0007621 2 0.115
regulation of membrane repolarization GO:0060306 7 0.115
visual behavior GO:0007632 45 0.114
anatomical structure maturation GO:0071695 49 0.114
growth hormone secretion GO:0030252 9 0.113
negative regulation of neuron apoptotic process GO:0043524 92 0.112
acid secretion GO:0046717 33 0.111
eating behavior GO:0042755 15 0.111
regulation of vesicle mediated transport GO:0060627 139 0.111
neuronal action potential GO:0019228 54 0.110
histone modification GO:0016570 159 0.110
purine nucleotide biosynthetic process GO:0006164 65 0.110
response to amine GO:0014075 16 0.110
protein targeting GO:0006605 143 0.109
Mouse
acetylcholine metabolic process GO:0008291 3 0.109
response to ethanol GO:0045471 18 0.108
response to oxidative stress GO:0006979 123 0.108
skeletal muscle organ development GO:0060538 163 0.108
Mouse
negative regulation of protein modification process GO:0031400 163 0.108
cellular response to acid chemical GO:0071229 68 0.107
Mouse
sterol homeostasis GO:0055092 45 0.107
Mouse
regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900211 4 0.107
detection of light stimulus GO:0009583 25 0.106
nephric duct formation GO:0072179 4 0.106
regulation of ion homeostasis GO:2000021 64 0.106
leukocyte activation involved in immune response GO:0002366 126 0.106
monovalent inorganic cation homeostasis GO:0055067 33 0.106
eye photoreceptor cell development GO:0042462 31 0.106
Zebrafish
ph elevation GO:0045852 3 0.105
regulation of carbohydrate catabolic process GO:0043470 12 0.105
negative regulation of hormone biosynthetic process GO:0032353 4 0.105
release of cytochrome c from mitochondria GO:0001836 23 0.103
branching morphogenesis of an epithelial tube GO:0048754 159 0.103
regulation of nucleotide biosynthetic process GO:0030808 34 0.103
positive regulation of osteoblast differentiation GO:0045669 34 0.103

Thrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
auditory system disease DOID:2742 0 0.972
nonsyndromic deafness DOID:0050563 0 0.972
sensory system disease DOID:0050155 0 0.972
disease of anatomical entity DOID:7 0 0.972
Human
nervous system disease DOID:863 0 0.972
thyroid gland disease DOID:50 0 0.875
Human
hypothyroidism DOID:1459 0 0.875
Human
endocrine system disease DOID:28 0 0.875
Human
congenital hypothyroidism DOID:0050328 0 0.360
autosomal recessive nonsyndromic deafness DOID:0050565 0 0.294
disease of cellular proliferation DOID:14566 0 0.146