Mus musculus

81 known processes

Ctla2a

cytotoxic T lymphocyte-associated protein 2 alpha

(Aliases: Ctla-2a)

Ctla2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
zymogen inhibition GO:0097341 1 0.894
Fly
inhibition of cysteine type endopeptidase activity GO:0097340 1 0.876
Fly
regulation of regulatory t cell differentiation GO:0045589 7 0.861
regulation of cysteine type endopeptidase activity GO:2000116 65 0.789
Fly
regulation of peptidase activity GO:0052547 96 0.781
Fly
negative regulation of hydrolase activity GO:0051346 71 0.716
Fly
lymphocyte differentiation GO:0030098 242 0.663
regulation of protein maturation GO:1903317 96 0.660
protein processing GO:0016485 163 0.650
negative regulation of proteolysis GO:0045861 74 0.647
Fly
negative regulation of protein processing GO:0010955 79 0.635
memory GO:0007613 58 0.633
Fly
negative regulation of molecular function GO:0044092 258 0.573
Fly
inflammatory response GO:0006954 244 0.571
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.560
Fly
regulation of inflammatory response GO:0050727 147 0.558
regulation of t cell differentiation GO:0045580 83 0.556
negative regulation of inflammatory response GO:0050728 61 0.551
regulation of cell activation GO:0050865 289 0.547
leukocyte differentiation GO:0002521 342 0.543
negative regulation of protein metabolic process GO:0051248 282 0.527
regulation of t cell activation GO:0050863 170 0.511
regulation of hydrolase activity GO:0051336 246 0.500
Fly
regulation of protein processing GO:0070613 96 0.475
regulation of leukocyte differentiation GO:1902105 159 0.470
negative regulation of cellular protein metabolic process GO:0032269 247 0.443
Fly
regulation of response to wounding GO:1903034 189 0.425
negative regulation of response to wounding GO:1903035 77 0.402
regulation of proteolysis GO:0030162 164 0.401
Fly
regulation of lymphocyte activation GO:0051249 240 0.394
learning or memory GO:0007611 148 0.281
Fly
regulation of lymphocyte differentiation GO:0045619 107 0.271
amine metabolic process GO:0009308 45 0.241
cellular amine metabolic process GO:0044106 44 0.195
cellular ketone metabolic process GO:0042180 84 0.173
regulation of cellular amino acid metabolic process GO:0006521 5 0.142
regulation of cellular ketone metabolic process GO:0010565 66 0.136
cell adhesion GO:0007155 329 0.133
protein maturation GO:0051604 176 0.131
regulation of apoptotic signaling pathway GO:2001233 197 0.121
single organismal cell cell adhesion GO:0016337 131 0.108
hemostasis GO:0007599 78 0.106
g protein coupled receptor signaling pathway GO:0007186 243 0.104
cell type specific apoptotic process GO:0097285 268 0.104
apoptotic signaling pathway GO:0097190 306 0.099
cellular amino acid metabolic process GO:0006520 103 0.094
positive regulation of programmed cell death GO:0043068 218 0.092
myeloid leukocyte differentiation GO:0002573 119 0.092
homeostasis of number of cells GO:0048872 210 0.087
coagulation GO:0050817 78 0.085
regulation of cytokine production GO:0001817 266 0.085
peptidyl amino acid modification GO:0018193 336 0.084
positive regulation of cell death GO:0010942 224 0.083
positive regulation of apoptotic process GO:0043065 217 0.082
immune effector process GO:0002252 321 0.082
myeloid cell differentiation GO:0030099 233 0.079
angiogenesis GO:0001525 201 0.075
response to insulin GO:0032868 100 0.075
wound healing GO:0042060 157 0.074
regulation of cellular amine metabolic process GO:0033238 20 0.072
hematopoietic progenitor cell differentiation GO:0002244 143 0.071
regulation of secretion GO:0051046 274 0.069
blood vessel morphogenesis GO:0048514 285 0.069
positive regulation of mapk cascade GO:0043410 170 0.069
blood coagulation GO:0007596 76 0.068
regulation of body fluid levels GO:0050878 162 0.067
peptidyl tyrosine modification GO:0018212 145 0.065
positive regulation of cellular amine metabolic process GO:0033240 5 0.064
cellular response to hormone stimulus GO:0032870 150 0.063
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
positive regulation of protein phosphorylation GO:0001934 242 0.060
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.059
regulation of homeostatic process GO:0032844 182 0.059
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
defense response to other organism GO:0098542 197 0.055
carbohydrate metabolic process GO:0005975 230 0.053
skeletal muscle organ development GO:0060538 163 0.053
cellular response to insulin stimulus GO:0032869 78 0.051
response to organonitrogen compound GO:0010243 246 0.051
anion transport GO:0006820 177 0.049
positive regulation of protein modification process GO:0031401 299 0.048
cell chemotaxis GO:0060326 81 0.048
single organism cell adhesion GO:0098602 156 0.046
response to peptide GO:1901652 136 0.045
mapk cascade GO:0000165 281 0.045
regulation of purine nucleotide metabolic process GO:1900542 169 0.044
response to lipopolysaccharide GO:0032496 128 0.044
regulation of cell cycle GO:0051726 281 0.044
organonitrogen compound catabolic process GO:1901565 264 0.044
peptidyl tyrosine phosphorylation GO:0018108 143 0.043
nitrogen compound transport GO:0071705 271 0.042
cation transport GO:0006812 399 0.042
nucleotide catabolic process GO:0009166 217 0.042
regulation of defense response GO:0031347 233 0.042
cellular response to peptide GO:1901653 92 0.041
regulation of cellular component biogenesis GO:0044087 181 0.041
divalent metal ion transport GO:0070838 172 0.041
regulation of protein transport GO:0051223 163 0.041
regulation of nucleotide metabolic process GO:0006140 169 0.041
positive regulation of defense response GO:0031349 124 0.041
positive regulation of hydrolase activity GO:0051345 148 0.041
transmembrane transport GO:0055085 412 0.040
cellular response to cytokine stimulus GO:0071345 189 0.039
muscle tissue development GO:0060537 308 0.039
cellular response to organonitrogen compound GO:0071417 145 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.039
regulation of establishment of protein localization GO:0070201 181 0.038
positive regulation of secretion by cell GO:1903532 114 0.038
cellular homeostasis GO:0019725 240 0.038
circulatory system process GO:0003013 197 0.037
muscle cell differentiation GO:0042692 261 0.037
ras protein signal transduction GO:0007265 77 0.037
endomembrane system organization GO:0010256 147 0.036
macromolecule catabolic process GO:0009057 281 0.036
t cell activation GO:0042110 289 0.035
negative regulation of apoptotic signaling pathway GO:2001234 104 0.035
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
rho protein signal transduction GO:0007266 32 0.034
protein secretion GO:0009306 111 0.034
maintenance of location GO:0051235 89 0.034
response to organic cyclic compound GO:0014070 198 0.033
response to inorganic substance GO:0010035 96 0.033
heterocycle catabolic process GO:0046700 280 0.033
intrinsic apoptotic signaling pathway GO:0097193 132 0.033
membrane organization GO:0061024 245 0.033
cell substrate adhesion GO:0031589 130 0.032
amide transport GO:0042886 138 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
peptide transport GO:0015833 133 0.031
muscle system process GO:0003012 141 0.031
purine containing compound metabolic process GO:0072521 311 0.031
nucleotide metabolic process GO:0009117 332 0.031
regulation of transferase activity GO:0051338 263 0.031
regulation of peptide secretion GO:0002791 77 0.031
cellular response to peptide hormone stimulus GO:0071375 92 0.030
purine nucleoside metabolic process GO:0042278 241 0.030
divalent inorganic cation transport GO:0072511 178 0.030
blood circulation GO:0008015 195 0.030
alpha beta t cell differentiation GO:0046632 69 0.030
regulation of organelle organization GO:0033043 289 0.030
positive regulation of organelle organization GO:0010638 128 0.030
striated muscle cell development GO:0055002 125 0.030
regulation of neuron death GO:1901214 134 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
chemotaxis GO:0006935 247 0.030
engulfment of apoptotic cell GO:0043652 3 0.030
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
response to acid chemical GO:0001101 111 0.030
protein catabolic process GO:0030163 221 0.029
aromatic compound catabolic process GO:0019439 286 0.029
glucose homeostasis GO:0042593 128 0.029
regulation of hormone levels GO:0010817 211 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
mitochondrion organization GO:0007005 134 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
regulation of hemostasis GO:1900046 28 0.028
urogenital system development GO:0001655 261 0.028
carbohydrate homeostasis GO:0033500 128 0.028
negative regulation of protein phosphorylation GO:0001933 126 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
leukocyte migration GO:0050900 124 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
cellular response to organic cyclic compound GO:0071407 87 0.027
positive regulation of nucleotide catabolic process GO:0030813 88 0.026
positive regulation of cell development GO:0010720 237 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
regulation of protein kinase activity GO:0045859 232 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
regulation of mapk cascade GO:0043408 248 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
forebrain development GO:0030900 302 0.025
exocytosis GO:0006887 121 0.025
positive regulation of cell adhesion GO:0045785 80 0.025
metal ion homeostasis GO:0055065 189 0.024
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.024
regulation of cell motility GO:2000145 236 0.024
reactive oxygen species metabolic process GO:0072593 84 0.024
response to growth factor GO:0070848 198 0.024
hormone secretion GO:0046879 128 0.024
negative regulation of phosphorylation GO:0042326 166 0.024
tissue homeostasis GO:0001894 115 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.023
response to peptide hormone GO:0043434 127 0.023
calcium ion homeostasis GO:0055074 127 0.023
positive regulation of response to wounding GO:1903036 66 0.023
gland development GO:0048732 330 0.023
regulation of actin filament based process GO:0032970 99 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
protein localization to membrane GO:0072657 108 0.023
organic anion transport GO:0015711 137 0.023
cation homeostasis GO:0055080 212 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
cytokine production GO:0001816 319 0.023
endocytosis GO:0006897 168 0.022
myeloid cell homeostasis GO:0002262 114 0.022
defense response to virus GO:0051607 68 0.022
response to steroid hormone GO:0048545 56 0.022
leukocyte activation involved in immune response GO:0002366 126 0.022
tissue migration GO:0090130 68 0.022
muscle fiber development GO:0048747 76 0.022
muscle contraction GO:0006936 101 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
lymphocyte homeostasis GO:0002260 64 0.022
sequestering of metal ion GO:0051238 19 0.022
negative regulation of protein maturation GO:1903318 79 0.022
regulation of binding GO:0051098 111 0.022
positive regulation of secretion GO:0051047 130 0.021
lipid biosynthetic process GO:0008610 179 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.021
negative regulation of endothelial cell migration GO:0010596 4 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
negative regulation of vasculature development GO:1901343 26 0.021
peptide secretion GO:0002790 114 0.021
cellular ion homeostasis GO:0006873 165 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
negative regulation of peptidase activity GO:0010466 46 0.021
Fly
positive regulation of cytokine production GO:0001819 174 0.021
anatomical structure homeostasis GO:0060249 145 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
positive regulation of cell motility GO:2000147 116 0.021
regulation of secretion by cell GO:1903530 249 0.021
sequestering of calcium ion GO:0051208 18 0.021
regulation of gtp catabolic process GO:0033124 113 0.020
cellular response to acid chemical GO:0071229 68 0.020
ion transmembrane transport GO:0034220 361 0.020
telencephalon development GO:0021537 186 0.020
cellular lipid metabolic process GO:0044255 323 0.020
regulation of cell adhesion GO:0030155 154 0.020
regulation of neuron apoptotic process GO:0043523 122 0.020
camera type eye development GO:0043010 266 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
guanosine containing compound metabolic process GO:1901068 144 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
negative regulation of secretion GO:0051048 61 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.020
neuron death GO:0070997 154 0.020
glycoprotein biosynthetic process GO:0009101 89 0.020
lipid transport GO:0006869 98 0.020
regulation of ion transport GO:0043269 215 0.019
regulation of transmembrane transport GO:0034762 128 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.019
striated muscle tissue development GO:0014706 293 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.019
positive regulation of cellular component biogenesis GO:0044089 94 0.019
regulation of cell migration GO:0030334 219 0.019
sensory perception GO:0007600 245 0.019
leukocyte apoptotic process GO:0071887 71 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
negative regulation of cytokine production GO:0001818 84 0.019
small molecule biosynthetic process GO:0044283 132 0.019
wound healing involved in inflammatory response GO:0002246 4 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
t cell differentiation GO:0030217 174 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
compound eye development GO:0048749 1 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
inflammatory response to wounding GO:0090594 4 0.018
myoblast differentiation GO:0045445 52 0.018
negative regulation of endopeptidase activity GO:0010951 44 0.018
Fly
regulation of metal ion transport GO:0010959 106 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.018
fat cell differentiation GO:0045444 160 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
regulation of cellular response to stress GO:0080135 159 0.018
second messenger mediated signaling GO:0019932 73 0.018
regulation of neuron differentiation GO:0045664 281 0.018
cellular chemical homeostasis GO:0055082 215 0.018
negative regulation of cell activation GO:0050866 111 0.018
regulation of production of molecular mediator of immune response GO:0002700 65 0.018
positive regulation of nervous system development GO:0051962 221 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
regulation of leukocyte apoptotic process GO:2000106 56 0.017
negative regulation of protein modification process GO:0031400 163 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
organelle localization GO:0051640 179 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
regulation of peptidyl serine phosphorylation GO:0033135 39 0.017
tissue remodeling GO:0048771 102 0.017
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.017
regulation of cell substrate adhesion GO:0010810 73 0.017
mitotic cell cycle process GO:1903047 159 0.017
neuron apoptotic process GO:0051402 142 0.017
placenta development GO:0001890 140 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
negative regulation of neuron death GO:1901215 98 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
cytoplasmic transport GO:0016482 234 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
regulation of anatomical structure size GO:0090066 178 0.016
epithelial cell proliferation GO:0050673 174 0.016
multicellular organismal signaling GO:0035637 91 0.016
regulation of cellular component size GO:0032535 121 0.016
regulation of muscle contraction GO:0006937 49 0.016
heart process GO:0003015 94 0.016
negative regulation of immune system process GO:0002683 209 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
regulation of interleukin 8 secretion GO:2000482 2 0.016
cellular response to amino acid stimulus GO:0071230 29 0.016
response to hypoxia GO:0001666 58 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
Fly
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
leukocyte homeostasis GO:0001776 79 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
negative regulation of ossification GO:0030279 49 0.016
developmental maturation GO:0021700 193 0.016
platelet activation GO:0030168 40 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.016
protein import GO:0017038 101 0.016
rhythmic process GO:0048511 174 0.016
regulation of intracellular transport GO:0032386 159 0.016
purine containing compound catabolic process GO:0072523 213 0.016
ameboidal type cell migration GO:0001667 128 0.016
positive regulation of camp mediated signaling GO:0043950 3 0.015
interleukin 8 secretion GO:0072606 3 0.015
positive regulation of cell activation GO:0050867 158 0.015
carboxylic acid transport GO:0046942 100 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
gtp catabolic process GO:0006184 143 0.015
regulation of action potential GO:0098900 4 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
regulation of system process GO:0044057 200 0.015
regulation of membrane potential GO:0042391 192 0.015
organelle fission GO:0048285 170 0.015
defense response to bacterium GO:0042742 119 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
regulation of cytokine secretion GO:0050707 61 0.015
regulation of protein secretion GO:0050708 82 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
regulation of wound healing GO:0061041 40 0.015
positive regulation of endopeptidase activity GO:0010950 43 0.014
cognition GO:0050890 149 0.014
Fly
skeletal system development GO:0001501 356 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
interleukin 8 production GO:0032637 4 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
organophosphate catabolic process GO:0046434 232 0.014
spermatid differentiation GO:0048515 115 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
ossification GO:0001503 216 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
peptide hormone secretion GO:0030072 109 0.014
spermatogenesis GO:0007283 284 0.014
regulation of protein catabolic process GO:0042176 108 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.014
glucose metabolic process GO:0006006 92 0.013
regulation of heart contraction GO:0008016 77 0.013
regulation of ion homeostasis GO:2000021 64 0.013
phagocytosis GO:0006909 66 0.013
heart contraction GO:0060047 93 0.013
oxidation reduction process GO:0055114 342 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
response to oxygen levels GO:0070482 62 0.013
energy derivation by oxidation of organic compounds GO:0015980 77 0.013
cellular protein complex assembly GO:0043623 116 0.013
positive regulation of kinase activity GO:0033674 155 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
nuclear division GO:0000280 158 0.013
peptidyl serine modification GO:0018209 83 0.013
negative regulation of secretion by cell GO:1903531 54 0.013
hexose metabolic process GO:0019318 98 0.013
actin filament organization GO:0007015 113 0.013
nephron tubule development GO:0072080 84 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
protein glycosylation GO:0006486 55 0.013
monosaccharide metabolic process GO:0005996 106 0.013
fatty acid metabolic process GO:0006631 121 0.013
alcohol metabolic process GO:0006066 116 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
regulation of muscle tissue development GO:1901861 97 0.013
signal transduction in absence of ligand GO:0038034 55 0.013
regulation of cell projection organization GO:0031344 206 0.013
response to amino acid GO:0043200 37 0.013
actin cytoskeleton organization GO:0030036 220 0.013
macromolecule glycosylation GO:0043413 55 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.012
cytosolic calcium ion transport GO:0060401 48 0.012
dna metabolic process GO:0006259 303 0.012
regulation of eosinophil migration GO:2000416 2 0.012
response to nutrient levels GO:0031667 109 0.012
skeletal muscle fiber development GO:0048741 58 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
muscle cell development GO:0055001 133 0.012
synaptic transmission GO:0007268 329 0.012
cell recognition GO:0008037 83 0.012
nucleoside metabolic process GO:0009116 246 0.012
negative regulation of cell cycle GO:0045786 123 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
cation transmembrane transport GO:0098655 266 0.012
positive regulation of proteolysis GO:0045862 85 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of engulfment of apoptotic cell GO:1901074 2 0.012
response to starvation GO:0042594 65 0.012
cholesterol homeostasis GO:0042632 44 0.012
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.012
positive regulation of cell migration GO:0030335 109 0.012
ear development GO:0043583 200 0.012
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.012
myeloid leukocyte activation GO:0002274 83 0.012
regulation of cell cycle process GO:0010564 160 0.012
positive regulation of ion transport GO:0043270 65 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
male gamete generation GO:0048232 285 0.012
protein localization to organelle GO:0033365 185 0.012
somitogenesis GO:0001756 69 0.012
nuclear transport GO:0051169 139 0.012
cell junction organization GO:0034330 77 0.012
negative regulation of b cell activation GO:0050869 27 0.012
regulation of neuron projection development GO:0010975 169 0.012
microtubule based process GO:0007017 236 0.012
response to extracellular stimulus GO:0009991 127 0.012
connective tissue development GO:0061448 179 0.012
actin filament bundle assembly GO:0051017 40 0.012
regulation of synaptic plasticity GO:0048167 87 0.012
regulation of protein complex assembly GO:0043254 83 0.012
regulation of lymphocyte apoptotic process GO:0070228 41 0.012
wnt signaling pathway GO:0016055 188 0.012
positive regulation of behavior GO:0048520 40 0.012
gonad development GO:0008406 141 0.012
integrin activation GO:0033622 8 0.012
cell growth GO:0016049 130 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
regulation of lipid biosynthetic process GO:0046890 54 0.012
stem cell differentiation GO:0048863 268 0.012
transmission of nerve impulse GO:0019226 76 0.012
organ regeneration GO:0031100 2 0.011
kidney morphogenesis GO:0060993 83 0.011
b cell activation GO:0042113 161 0.011
single fertilization GO:0007338 82 0.011
respiratory system development GO:0060541 190 0.011
lymphocyte apoptotic process GO:0070227 54 0.011
regulation of vasculature development GO:1901342 88 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.011
positive regulation of interleukin 6 secretion GO:2000778 1 0.011
fibrinolysis GO:0042730 3 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
neutrophil chemotaxis GO:0030593 36 0.011
thrombin receptor signaling pathway GO:0070493 2 0.011
regulation of protein localization GO:0032880 231 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
hexose transport GO:0008645 56 0.011
glycoprotein metabolic process GO:0009100 116 0.011
skin development GO:0043588 220 0.011
kidney development GO:0001822 213 0.011
regulation of calcium ion transport GO:0051924 69 0.011
cytokine secretion GO:0050663 72 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
action potential GO:0001508 78 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
lipid localization GO:0010876 126 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
long chain fatty acid import GO:0044539 2 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
anion transmembrane transport GO:0098656 71 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
intracellular protein transport GO:0006886 204 0.011
cellular response to oxidative stress GO:0034599 76 0.011
cell maturation GO:0048469 127 0.011
positive regulation of interleukin 8 production GO:0032757 2 0.011
regulation of multi organism process GO:0043900 111 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
regulation of myotube differentiation GO:0010830 62 0.011
regulation of peptide transport GO:0090087 91 0.011
response to fibroblast growth factor GO:0071774 47 0.011
adult behavior GO:0030534 135 0.011
neuromuscular process GO:0050905 99 0.010
myeloid leukocyte migration GO:0097529 57 0.010

Ctla2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.028
disease of anatomical entity DOID:7 0 0.028
hematopoietic system disease DOID:74 0 0.028
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.013
blood coagulation disease DOID:1247 0 0.012
sensory system disease DOID:0050155 0 0.011