|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.470
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.397
|
Worm Fly |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.375
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.369
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.327
|
|
|
|
mitochondrion transport along microtubule
|
GO:0047497 |
3 |
0.325
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.295
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.280
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.273
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.267
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.258
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.238
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.229
|
Worm Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.228
|
Worm |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.227
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.219
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.216
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.201
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.201
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.193
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.192
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.188
|
Worm |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.185
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.184
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.184
|
Worm |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.176
|
Mouse |
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.176
|
Worm |
|
|
establishment of mitochondrion localization
|
GO:0051654 |
4 |
0.175
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.158
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.155
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
128 |
0.155
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.153
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.153
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.152
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.152
|
Worm Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.147
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.145
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.142
|
Worm Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.140
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.138
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.137
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.137
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.136
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.133
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.132
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.131
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.129
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.126
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.124
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.123
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.122
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.122
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.121
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.121
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.120
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.120
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.117
|
Worm |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.115
|
Worm Fly |
|
|
cation transport
|
GO:0006812 |
399 |
0.112
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.112
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.112
|
Zebrafish Worm Fly |
|
|
lipid localization
|
GO:0010876 |
126 |
0.111
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.110
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.108
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
1 |
0.108
|
|
|
|
hindbrain morphogenesis
|
GO:0021575 |
46 |
0.108
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.108
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.106
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.105
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.104
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.103
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.102
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.102
|
Fly |
|
|
membrane organization
|
GO:0061024 |
245 |
0.101
|
Mouse Worm |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.101
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.101
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.100
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.100
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.099
|
|
|
|
cerebellar cortex morphogenesis
|
GO:0021696 |
32 |
0.098
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.097
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.097
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.096
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.096
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.095
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.095
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.094
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.092
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.091
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.091
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.090
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.090
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.090
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.090
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.090
|
|
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.089
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.089
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.088
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.088
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.087
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.087
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.087
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.086
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.086
|
|
|
|
ventricular cardiac myofibril assembly
|
GO:0055005 |
3 |
0.085
|
|
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.085
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.085
|
|
|
|
memory
|
GO:0007613 |
58 |
0.085
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.084
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.083
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.083
|
Mouse |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.083
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.082
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.081
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.080
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.079
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.079
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.078
|
Fly |
|
|
cerebellum development
|
GO:0021549 |
77 |
0.078
|
|
|
|
golgi to endosome transport
|
GO:0006895 |
3 |
0.077
|
Mouse |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.076
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.076
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.076
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.076
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.075
|
|
|
|
regulation of cell growth involved in cardiac muscle cell development
|
GO:0061050 |
3 |
0.075
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.074
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.074
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.074
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.074
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.074
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.073
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.073
|
Worm |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.073
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.072
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.072
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.072
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.072
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.072
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.072
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.071
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.071
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.071
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.071
|
|
|
|
regulation of mrna polyadenylation
|
GO:1900363 |
1 |
0.071
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
34 |
0.070
|
|
|
|
rna 3 end processing
|
GO:0031123 |
20 |
0.070
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.070
|
Fly |
|
|
oogenesis
|
GO:0048477 |
56 |
0.069
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.069
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.068
|
Fly |
|
|
physiological muscle hypertrophy
|
GO:0003298 |
3 |
0.068
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.068
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.068
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.068
|
Worm |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.067
|
Fly |
|
|
nuclear division
|
GO:0000280 |
158 |
0.067
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.067
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.066
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.066
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.066
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.065
|
Worm |
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
21 |
0.065
|
|
|
|
cerebellar cortex development
|
GO:0021695 |
48 |
0.065
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.065
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.064
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.064
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.064
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.064
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
43 |
0.063
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.063
|
|
|
|
physiological cardiac muscle hypertrophy
|
GO:0003301 |
3 |
0.063
|
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.063
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.062
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.062
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.062
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.061
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.061
|
|
|
|
negative regulation of purine nucleotide catabolic process
|
GO:0033122 |
9 |
0.061
|
|
|
|
regulation of cytoplasmic translation
|
GO:2000765 |
4 |
0.061
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.060
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.060
|
Zebrafish Worm |
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.060
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.060
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.060
|
Fly |
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.060
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.059
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.059
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.059
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.058
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.058
|
|
|
|
regulation of sarcomere organization
|
GO:0060297 |
4 |
0.058
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.058
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.058
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.057
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.056
|
Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.056
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.055
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.055
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.055
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.055
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.055
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.054
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.054
|
Worm Fly |
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.054
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.054
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.054
|
Worm |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.054
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.053
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.053
|
Fly |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.053
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.053
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.053
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.053
|
Fly |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.053
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.053
|
|
|
|
plus end directed organelle transport along microtubule
|
GO:0072386 |
2 |
0.052
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.052
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.052
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.052
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.052
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.051
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.051
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.051
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.051
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.051
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.050
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.050
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.050
|
Worm |
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.050
|
Fly |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.050
|
|
|
|
cell cycle switching mitotic to meiotic cell cycle
|
GO:0051728 |
1 |
0.049
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.049
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.049
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.049
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.048
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.048
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.048
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.048
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.048
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.048
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.048
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.048
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.047
|
|
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.047
|
Worm |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.047
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.047
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.047
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.047
|
Worm |
|
|
cell differentiation in hindbrain
|
GO:0021533 |
24 |
0.047
|
|
|
|
germline cell cycle switching mitotic to meiotic cell cycle
|
GO:0051729 |
1 |
0.047
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.046
|
|
|
|
acetate ester transport
|
GO:1901374 |
2 |
0.046
|
|
|
|
filopodium assembly
|
GO:0046847 |
19 |
0.046
|
Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.046
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.046
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.046
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.045
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.045
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.045
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.045
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.045
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.045
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.045
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.045
|
|
|
|
positive regulation of glutamate secretion
|
GO:0014049 |
2 |
0.045
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.045
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.044
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.044
|
|
|
|
regulation of b cell tolerance induction
|
GO:0002661 |
2 |
0.044
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.044
|
Worm |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.044
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.044
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.044
|
|
|
|
negative regulation of mesenchymal cell proliferation
|
GO:0072201 |
3 |
0.043
|
|
|
|
synapsis
|
GO:0007129 |
34 |
0.043
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.043
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.043
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.043
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.043
|
|
|
|
response to ischemia
|
GO:0002931 |
14 |
0.043
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.043
|
Fly |
|
|
mrna 3 end processing
|
GO:0031124 |
16 |
0.043
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.043
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.042
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.042
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
15 |
0.042
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.042
|
Worm Fly |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.042
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.042
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.041
|
|
|
|
regulation of behavioral fear response
|
GO:2000822 |
2 |
0.041
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.041
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.041
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.041
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.040
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.040
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.040
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.040
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.040
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.040
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.040
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.039
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.039
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.039
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.039
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.039
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.039
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.039
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
10 |
0.039
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.039
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.039
|
Zebrafish Worm |
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.038
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.038
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.038
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.038
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.038
|
Worm |
|
|
synaptonemal complex assembly
|
GO:0007130 |
13 |
0.038
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.038
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.038
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.038
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.038
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.038
|
Mouse |
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.038
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.037
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.037
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.037
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.037
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.037
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.037
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.036
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.036
|
|
|
|
clara cell differentiation
|
GO:0060486 |
4 |
0.036
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.036
|
|
|
|
inositol phosphate mediated signaling
|
GO:0048016 |
13 |
0.036
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.036
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.036
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.036
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.036
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.035
|
Mouse |
|
|
gene silencing by mirna
|
GO:0035195 |
10 |
0.035
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.035
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.035
|
|
|
|
regulation of mesenchymal cell proliferation involved in lung development
|
GO:2000790 |
2 |
0.035
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.035
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.035
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.035
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.035
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.034
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.034
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.034
|
|
|
|
microtubule sliding
|
GO:0051012 |
1 |
0.034
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.034
|
Fly |
|
|
cerebellar granular layer formation
|
GO:0021684 |
9 |
0.033
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.033
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.033
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.033
|
Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.033
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.033
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.033
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.033
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.033
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.033
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.033
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.033
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.032
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.032
|
Mouse |
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.032
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.032
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.032
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.032
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.032
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.032
|
|
|
|
cerebellar cortex formation
|
GO:0021697 |
22 |
0.032
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.032
|
|
|
|
cellular response to antibiotic
|
GO:0071236 |
4 |
0.032
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.032
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.032
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.032
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.032
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.031
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.031
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.031
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.031
|
|
|
|
regulation of mrna 3 end processing
|
GO:0031440 |
6 |
0.031
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.031
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.031
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.031
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.030
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.030
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.030
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.030
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.030
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.030
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.030
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.030
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.030
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.030
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.030
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.029
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.029
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.029
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.029
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.029
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.029
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.029
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
41 |
0.029
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.029
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
16 |
0.029
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.029
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.029
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.029
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.029
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.029
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.029
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.029
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.029
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.029
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.029
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.029
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.028
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.028
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.028
|
|
|
|
cerebellar granular layer development
|
GO:0021681 |
13 |
0.028
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.028
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.028
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.028
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.028
|
Worm |
|
|
somitogenesis
|
GO:0001756 |
69 |
0.028
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.028
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.028
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.028
|
|
|
|
chromosome organization involved in meiosis
|
GO:0070192 |
39 |
0.027
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.027
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.027
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.027
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.027
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.027
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.027
|
|
|
|
chromatin mediated maintenance of transcription
|
GO:0048096 |
2 |
0.027
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.027
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
4 |
0.027
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.027
|
|
|
|
cerebellar granular layer morphogenesis
|
GO:0021683 |
10 |
0.027
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.027
|
|
|
|
response to inactivity
|
GO:0014854 |
4 |
0.027
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.027
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.027
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.027
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.027
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.027
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.027
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.027
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.027
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.027
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.027
|
|
|
|
cerebellar granule cell precursor tangential migration
|
GO:0021935 |
1 |
0.027
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.027
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.026
|
Worm |
|
|
neuron death
|
GO:0070997 |
154 |
0.026
|
|
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
6 |
0.026
|
|
|
|
lateral mesodermal cell differentiation
|
GO:0048371 |
3 |
0.026
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.026
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.026
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.026
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.026
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.026
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.026
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.026
|
Fly |
|
|
liver development
|
GO:0001889 |
66 |
0.026
|
|
|
|
anatomical structure arrangement
|
GO:0048532 |
20 |
0.026
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.026
|
Worm |
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.026
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.026
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.025
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.025
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.025
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.025
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.025
|
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
23 |
0.025
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.025
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.025
|
Worm |
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.025
|
Zebrafish Worm |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.025
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.025
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.024
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.024
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.024
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.024
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.024
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.024
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.024
|
|
