Mus musculus

24 known processes

Pde6b

phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide

(Aliases: rd10,rd-1,Pdeb,rd,r,MGC150321,rd1)

Pde6b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
visual perception GO:0007601 52 0.651
Mouse
rhodopsin mediated signaling pathway GO:0016056 4 0.598
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.563
phototransduction GO:0007602 17 0.549
Mouse
amine metabolic process GO:0009308 45 0.542
retina development in camera type eye GO:0060041 119 0.527
g protein coupled receptor signaling pathway GO:0007186 243 0.494
action potential GO:0001508 78 0.485
response to radiation GO:0009314 165 0.436
blood circulation GO:0008015 195 0.393
circadian sleep wake cycle rem sleep GO:0042747 1 0.391
response to light stimulus GO:0009416 135 0.389
muscle system process GO:0003012 141 0.385
detection of light stimulus GO:0009583 25 0.383
sensory perception GO:0007600 245 0.362
Mouse
circadian sleep wake cycle non rem sleep GO:0042748 2 0.348
regulation of dopamine secretion GO:0014059 9 0.334
regulation of circadian sleep wake cycle GO:0042749 3 0.310
circulatory system process GO:0003013 197 0.300
stem cell development GO:0048864 219 0.286
retina morphogenesis in camera type eye GO:0060042 45 0.285
Mouse
multicellular organism growth GO:0035264 161 0.284
neural retina development GO:0003407 41 0.276
Mouse
regulation of response to wounding GO:1903034 189 0.255
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.252
metanephric loop of henle development GO:0072236 4 0.243
multicellular organismal homeostasis GO:0048871 164 0.236
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.233
cell division GO:0051301 120 0.229
ear development GO:0043583 200 0.212
regulation of secretion GO:0051046 274 0.211
optic nerve development GO:0021554 8 0.209
multicellular organismal signaling GO:0035637 91 0.208
leukocyte differentiation GO:0002521 342 0.199
sensory perception of light stimulus GO:0050953 54 0.199
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.197
lens development in camera type eye GO:0002088 62 0.197
cytokine production GO:0001816 319 0.196
adult behavior GO:0030534 135 0.195
circadian rhythm GO:0007623 114 0.193
tissue homeostasis GO:0001894 115 0.192
eye photoreceptor cell differentiation GO:0001754 41 0.191
Mouse
detection of external stimulus GO:0009581 61 0.185
regulation of membrane potential GO:0042391 192 0.185
detection of abiotic stimulus GO:0009582 60 0.185
heterocycle catabolic process GO:0046700 280 0.182
Mouse
cranial nerve development GO:0021545 41 0.180
anatomical structure homeostasis GO:0060249 145 0.179
extracellular matrix organization GO:0030198 147 0.175
camera type eye development GO:0043010 266 0.173
organophosphate biosynthetic process GO:0090407 122 0.170
Mouse
negative regulation of cell proliferation GO:0008285 296 0.168
negative regulation of interleukin 1 beta production GO:0032691 5 0.165
metanephric dct cell differentiation GO:0072240 3 0.164
regulation of cellular amino acid metabolic process GO:0006521 5 0.162
metanephric ascending thin limb development GO:0072218 2 0.162
heart contraction GO:0060047 93 0.161
ribose phosphate biosynthetic process GO:0046390 59 0.160
Mouse
eye photoreceptor cell development GO:0042462 31 0.158
Mouse
positive regulation of dopamine secretion GO:0033603 2 0.149
ectodermal cell differentiation GO:0010668 3 0.146
cellular amino acid metabolic process GO:0006520 103 0.145
generation of ovulation cycle rhythm GO:0060112 1 0.139
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.138
glial cell development GO:0021782 54 0.138
mechanoreceptor differentiation GO:0042490 67 0.135
catecholamine metabolic process GO:0006584 30 0.135
nerve development GO:0021675 67 0.133
regulation of cytokine production GO:0001817 266 0.132
axon ensheathment GO:0008366 76 0.128
epidermis development GO:0008544 187 0.127
phototransduction visible light GO:0007603 6 0.126
Mouse
adaptive immune response GO:0002250 155 0.125
regulation of leukocyte differentiation GO:1902105 159 0.118
response to oxygen levels GO:0070482 62 0.116
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.115
regulation of defense response GO:0031347 233 0.115
Mouse
neurohypophysis development GO:0021985 2 0.115
sensory perception of sound GO:0007605 97 0.114
regulation of circadian rhythm GO:0042752 58 0.113
lateral geniculate nucleus development GO:0021771 1 0.113
wound healing GO:0042060 157 0.112
diencephalon development GO:0021536 63 0.112
stem cell differentiation GO:0048863 268 0.111
photoreceptor cell differentiation GO:0046530 52 0.110
Mouse
cell maturation GO:0048469 127 0.110
forebrain generation of neurons GO:0021872 63 0.107
regulation of protein kinase activity GO:0045859 232 0.106
telencephalon development GO:0021537 186 0.106
negative regulation of secretion GO:0051048 61 0.105
inner cell mass cell fate commitment GO:0001827 2 0.105
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.105
proprioception GO:0019230 4 0.104
b cell activation GO:0042113 161 0.103
brain segmentation GO:0035284 3 0.102
neuronal action potential GO:0019228 54 0.101
locomotory behavior GO:0007626 195 0.100
regulation of system process GO:0044057 200 0.100
purine containing compound biosynthetic process GO:0072522 70 0.100
Mouse
ascending thin limb development GO:0072021 2 0.100
positive regulation of secretion by cell GO:1903532 114 0.099
regulation of rhodopsin gene expression GO:0007468 3 0.099
negative regulation of action potential GO:0045759 1 0.098
neuron neuron synaptic transmission GO:0007270 69 0.098
organonitrogen compound biosynthetic process GO:1901566 192 0.096
Mouse
ectodermal cell fate commitment GO:0001712 1 0.096
cellular response to light stimulus GO:0071482 19 0.096
cell recognition GO:0008037 83 0.096
myelination in peripheral nervous system GO:0022011 19 0.096
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.095
t cell activation GO:0042110 289 0.095
camera type eye photoreceptor cell differentiation GO:0060219 15 0.095
Mouse
detection of visible light GO:0009584 14 0.094
Mouse
detection of stimulus GO:0051606 84 0.093
regulation of kinase activity GO:0043549 249 0.093
bone remodeling GO:0046849 53 0.093
immune effector process GO:0002252 321 0.092
bmp signaling pathway GO:0030509 93 0.092
metanephric thick ascending limb development GO:0072233 2 0.091
skeletal system development GO:0001501 356 0.090
ventricular compact myocardium morphogenesis GO:0003223 2 0.090
positive regulation of catecholamine secretion GO:0033605 2 0.090
cell proliferation in forebrain GO:0021846 30 0.089
regulation of cellular amine metabolic process GO:0033238 20 0.089
ion transmembrane transport GO:0034220 361 0.088
nuclear division GO:0000280 158 0.087
metanephric nephron epithelium development GO:0072243 19 0.086
regulation of interleukin 1 production GO:0032652 26 0.086
sensory perception of mechanical stimulus GO:0050954 107 0.086
forebrain cell migration GO:0021885 58 0.086
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.081
telencephalon cell migration GO:0022029 55 0.081
sensory organ morphogenesis GO:0090596 242 0.080
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.080
Human Mouse
regulation of inflammatory response GO:0050727 147 0.080
Mouse
positive regulation of rhodopsin gene expression GO:0045872 2 0.079
muscle tissue development GO:0060537 308 0.079
b cell differentiation GO:0030183 78 0.078
sensory perception of smell GO:0007608 26 0.078
epithalamus development GO:0021538 2 0.078
regulation of asymmetric cell division GO:0009786 4 0.078
tumor necrosis factor production GO:0032640 50 0.077
sensory perception of chemical stimulus GO:0007606 51 0.077
positive regulation of protein phosphorylation GO:0001934 242 0.077
gland development GO:0048732 330 0.075
regulation of transferase activity GO:0051338 263 0.075
negative regulation of cytokine production GO:0001818 84 0.075
regulation of reproductive process GO:2000241 66 0.075
thick ascending limb development GO:0072023 2 0.074
cellular calcium ion homeostasis GO:0006874 119 0.074
Human
transmission of nerve impulse GO:0019226 76 0.074
astrocyte fate commitment GO:0060018 4 0.074
spermatogenesis GO:0007283 284 0.074
sensory system development GO:0048880 3 0.073
positive regulation of protein modification process GO:0031401 299 0.073
cellular amine metabolic process GO:0044106 44 0.073
organelle fission GO:0048285 170 0.072
mesenchymal cell development GO:0014031 93 0.071
learning or memory GO:0007611 148 0.070
developmental maturation GO:0021700 193 0.070
auditory receptor cell fate determination GO:0042668 3 0.069
auditory receptor cell fate specification GO:0042667 1 0.068
heart process GO:0003015 94 0.068
positive regulation of protein kinase activity GO:0045860 144 0.067
embryonic organ morphogenesis GO:0048562 276 0.067
response to decreased oxygen levels GO:0036293 59 0.067
axonogenesis GO:0007409 274 0.066
ensheathment of neurons GO:0007272 76 0.065
regionalization GO:0003002 337 0.064
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.064
phenol containing compound metabolic process GO:0018958 60 0.064
muscle contraction GO:0006936 101 0.064
cardiac ventricle development GO:0003231 83 0.064
cellular response to acid chemical GO:0071229 68 0.063
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.063
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.063
forebrain development GO:0030900 302 0.063
neuron death GO:0070997 154 0.062
response to hypoxia GO:0001666 58 0.061
feeding behavior GO:0007631 62 0.061
regulation of feeding behavior GO:0060259 3 0.061
sperm motility GO:0030317 47 0.061
aromatic compound catabolic process GO:0019439 286 0.060
Mouse
positive regulation of apoptotic process GO:0043065 217 0.060
keratinocyte differentiation GO:0030216 48 0.060
negative regulation of neuron death GO:1901215 98 0.059
regulation of neuron death GO:1901214 134 0.059
extracellular structure organization GO:0043062 148 0.059
nucleoside phosphate metabolic process GO:0006753 338 0.059
Human Mouse
macula densa development GO:0072024 1 0.059
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.059
vestibulocochlear nerve development GO:0021562 7 0.059
positive regulation of programmed cell death GO:0043068 218 0.059
cerebral cortex development GO:0021987 86 0.058
mitochondrion organization GO:0007005 134 0.058
glycosyl compound metabolic process GO:1901657 246 0.058
Human
protein secretion GO:0009306 111 0.058
regulation of tissue remodeling GO:0034103 38 0.057
inner ear morphogenesis GO:0042472 101 0.057
organophosphate catabolic process GO:0046434 232 0.056
Mouse
lymphocyte differentiation GO:0030098 242 0.056
adult locomotory behavior GO:0008344 91 0.056
regulation of cell cycle GO:0051726 281 0.055
ribose phosphate metabolic process GO:0019693 291 0.054
Human Mouse
conditioned taste aversion GO:0001661 4 0.054
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.054
cellular ketone metabolic process GO:0042180 84 0.054
multi organism behavior GO:0051705 62 0.053
cerebral cortex radially oriented cell migration GO:0021799 31 0.053
pancreatic pp cell fate commitment GO:0003329 2 0.053
digestive tract development GO:0048565 190 0.052
segmentation GO:0035282 93 0.052
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.052
regulation of blood circulation GO:1903522 93 0.051
negative regulation of nervous system development GO:0051961 156 0.051
nitrogen compound transport GO:0071705 271 0.051
sclerotome development GO:0061056 4 0.050
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.050
purine containing compound metabolic process GO:0072521 311 0.050
Human Mouse
myelination GO:0042552 74 0.050
nucleoside metabolic process GO:0009116 246 0.049
Human
auditory receptor cell differentiation GO:0042491 37 0.049
negative regulation of secretion by cell GO:1903531 54 0.049
epithelial cell development GO:0002064 159 0.049
purine nucleoside metabolic process GO:0042278 241 0.049
Human
multi organism reproductive behavior GO:0044705 29 0.048
ribonucleotide metabolic process GO:0009259 291 0.048
Human Mouse
lens morphogenesis in camera type eye GO:0002089 24 0.048
positive regulation of cellular amine metabolic process GO:0033240 5 0.048
regulation of neuron differentiation GO:0045664 281 0.048
dopamine metabolic process GO:0042417 23 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
Human Mouse
calcium ion transport GO:0006816 159 0.047
regulation of action potential GO:0098900 4 0.047
positive regulation of cell death GO:0010942 224 0.046
forebrain ventricular zone progenitor cell division GO:0021869 6 0.046
cellular response to external stimulus GO:0071496 88 0.046
Mouse
skin development GO:0043588 220 0.046
carbohydrate derivative biosynthetic process GO:1901137 183 0.046
Mouse
endocytosis GO:0006897 168 0.046
protein ubiquitination GO:0016567 171 0.046
regulation of secretion by cell GO:1903530 249 0.046
cation homeostasis GO:0055080 212 0.045
Human
stem cell maintenance GO:0019827 130 0.045
central nervous system neuron differentiation GO:0021953 162 0.045
mapk cascade GO:0000165 281 0.044
monoamine transport GO:0015844 33 0.044
negative regulation of phosphate metabolic process GO:0045936 184 0.044
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.043
positive regulation of synaptic transmission dopaminergic GO:0032226 5 0.043
nucleotide metabolic process GO:0009117 332 0.043
Human Mouse
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.043
cell fate commitment GO:0045165 210 0.043
regulation of cellular catabolic process GO:0031329 242 0.043
negative regulation of protein metabolic process GO:0051248 282 0.043
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.043
ectoderm formation GO:0001705 3 0.043
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.043
ear morphogenesis GO:0042471 118 0.042
regulation of systemic arterial blood pressure GO:0003073 61 0.042
cellular response to abiotic stimulus GO:0071214 56 0.042
Mouse
negative regulation of immune system process GO:0002683 209 0.042
mechanosensory behavior GO:0007638 6 0.042
respiratory system development GO:0060541 190 0.042
pancreatic a cell fate commitment GO:0003326 2 0.042
cell type specific apoptotic process GO:0097285 268 0.042
epithelial cell morphogenesis GO:0003382 41 0.041
striated muscle tissue development GO:0014706 293 0.041
cerebral cortex neuron differentiation GO:0021895 19 0.041
cellular divalent inorganic cation homeostasis GO:0072503 127 0.041
Human
actin cytoskeleton organization GO:0030036 220 0.041
carbohydrate biosynthetic process GO:0016051 74 0.040
somatotropin secreting cell development GO:0060133 2 0.040
positive regulation of kinase activity GO:0033674 155 0.040
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.040
myeloid leukocyte differentiation GO:0002573 119 0.040
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.040
dopamine secretion GO:0014046 9 0.040
purine nucleotide metabolic process GO:0006163 302 0.039
Human Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.039
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.039
positive regulation of cell development GO:0010720 237 0.039
glial cell differentiation GO:0010001 131 0.039
negative regulation of cell development GO:0010721 169 0.039
digestive system development GO:0055123 200 0.039
inflammatory response GO:0006954 244 0.038
Mouse
cellular metal ion homeostasis GO:0006875 151 0.038
Human
regulation of neuron apoptotic process GO:0043523 122 0.038
positive regulation of secretion GO:0051047 130 0.038
norepinephrine secretion GO:0048243 2 0.038
regulation of multi organism process GO:0043900 111 0.038
regulation of lymphocyte activation GO:0051249 240 0.037
regulation of neural retina development GO:0061074 3 0.037
purine ribonucleotide biosynthetic process GO:0009152 59 0.037
Mouse
central nervous system neuron development GO:0021954 67 0.037
regulation of protein serine threonine kinase activity GO:0071900 157 0.037
dentate gyrus development GO:0021542 14 0.037
visual behavior GO:0007632 45 0.036
protein localization to organelle GO:0033365 185 0.036
nucleoside phosphate biosynthetic process GO:1901293 79 0.036
Mouse
cerebral cortex cell migration GO:0021795 44 0.036
limbic system development GO:0021761 72 0.036
habenula development GO:0021986 2 0.036
cardiac muscle tissue morphogenesis GO:0055008 44 0.036
norepinephrine transport GO:0015874 2 0.036
osteoclast differentiation GO:0030316 62 0.036
cell fate specification GO:0001708 72 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.035
Human
limb morphogenesis GO:0035108 149 0.035
hemangioblast cell differentiation GO:0060217 1 0.035
cellular macromolecule catabolic process GO:0044265 206 0.035
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.035
carbohydrate homeostasis GO:0033500 128 0.035
neuron apoptotic process GO:0051402 142 0.035
hypothalamus cell differentiation GO:0021979 8 0.035
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.034
positive regulation of nervous system development GO:0051962 221 0.034
membrane depolarization GO:0051899 64 0.034
negative regulation of molecular function GO:0044092 258 0.034
dopamine transport GO:0015872 15 0.034
ventricular cardiac muscle cell action potential GO:0086005 4 0.034
response to temperature stimulus GO:0009266 55 0.034
oxidation reduction process GO:0055114 342 0.033
developmental pigmentation GO:0048066 40 0.033
metanephric tubule development GO:0072170 18 0.033
hindbrain development GO:0030902 128 0.033
spermatid development GO:0007286 108 0.033
developmental growth involved in morphogenesis GO:0060560 138 0.033
hypothalamus development GO:0021854 16 0.033
gastrulation GO:0007369 116 0.033
regulation of glial cell differentiation GO:0045685 41 0.033
regulation of cellular component biogenesis GO:0044087 181 0.032
divalent metal ion transport GO:0070838 172 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
Mouse
positive regulation of heart rate GO:0010460 10 0.032
negative regulation of phosphorus metabolic process GO:0010563 184 0.032
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.032
Mouse
interleukin 1 beta production GO:0032611 30 0.032
cellular homeostasis GO:0019725 240 0.032
Human
equilibrioception GO:0050957 3 0.032
regulation of vesicle mediated transport GO:0060627 139 0.032
regulation of exit from mitosis GO:0007096 1 0.031
dct cell differentiation GO:0072069 3 0.031
ribonucleotide biosynthetic process GO:0009260 59 0.031
Mouse
nephron epithelium development GO:0072009 92 0.031
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.031
catecholamine secretion GO:0050432 15 0.031
muscle tissue morphogenesis GO:0060415 53 0.031
regulation of homeostatic process GO:0032844 182 0.031
hair cell differentiation GO:0035315 40 0.031
renal tubule development GO:0061326 87 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
negative regulation of phosphorylation GO:0042326 166 0.030
cyclic nucleotide biosynthetic process GO:0009190 44 0.030
Mouse
regulation of proteolysis GO:0030162 164 0.030
positive regulation of homeostatic process GO:0032846 64 0.030
chemotaxis GO:0006935 247 0.030
transmembrane transport GO:0055085 412 0.030
cardiac chamber development GO:0003205 108 0.030
regulation of norepinephrine secretion GO:0014061 2 0.030
visceral serous pericardium development GO:0061032 2 0.029
mesenchyme development GO:0060485 152 0.029
regulation of muscle system process GO:0090257 80 0.029
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.029
gonad morphogenesis GO:0035262 1 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
Human
synaptic transmission GO:0007268 329 0.029
regulation of cell projection organization GO:0031344 206 0.029
pigmentation GO:0043473 71 0.029
negative regulation of lymphocyte activation GO:0051250 91 0.029
peripheral nervous system development GO:0007422 53 0.029
response to food GO:0032094 17 0.029
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
response to oxidative stress GO:0006979 123 0.028
retinal cone cell development GO:0046549 8 0.028
Mouse
cellular ion homeostasis GO:0006873 165 0.028
Human
melanocyte differentiation GO:0030318 25 0.028
heart formation GO:0060914 16 0.028
light adaption GO:0036367 2 0.028
smooth muscle contraction GO:0006939 44 0.028
negative regulation of cellular amine metabolic process GO:0033239 1 0.028
single organism nuclear import GO:1902593 95 0.028
immunoglobulin secretion involved in immune response GO:0002380 2 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.027
transdifferentiation GO:0060290 1 0.027
acetate ester transport GO:1901374 2 0.027
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 12 0.027
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.027
positive regulation of neural precursor cell proliferation GO:2000179 42 0.027
neural crest cell differentiation GO:0014033 54 0.027
positive regulation of keratinocyte proliferation GO:0010838 4 0.027
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.027
cation transmembrane transport GO:0098655 266 0.027
synapse organization GO:0050808 125 0.027
embryonic skeletal system morphogenesis GO:0048704 91 0.027
response to cocaine GO:0042220 14 0.027
mating GO:0007618 27 0.026
leukocyte mediated immunity GO:0002443 174 0.026
positive regulation of exit from mitosis GO:0031536 1 0.026
astrocyte differentiation GO:0048708 43 0.026
divalent inorganic cation transport GO:0072511 178 0.026
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.026
compound eye development GO:0048749 1 0.026
regulation of ion transport GO:0043269 215 0.026
neuron fate specification GO:0048665 30 0.026
regulation of anterior head development GO:2000742 2 0.026
neuromuscular process GO:0050905 99 0.026
regulation of tumor necrosis factor production GO:0032680 49 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
bone resorption GO:0045453 38 0.026
cellular response to oxidative stress GO:0034599 76 0.026
schwann cell development GO:0014044 22 0.026
regulation of protein secretion GO:0050708 82 0.026
multi multicellular organism process GO:0044706 109 0.026
inorganic cation transmembrane transport GO:0098662 207 0.025
somatotropin secreting cell differentiation GO:0060126 4 0.025
trigeminal nerve development GO:0021559 10 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
Mouse
cellular chemical homeostasis GO:0055082 215 0.025
Human
b cell mediated immunity GO:0019724 71 0.025
regulation of interleukin 6 production GO:0032675 55 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.025
regulation of catecholamine metabolic process GO:0042069 10 0.025
cellular component assembly involved in morphogenesis GO:0010927 139 0.025
forebrain neuron differentiation GO:0021879 52 0.025
immunoglobulin mediated immune response GO:0016064 69 0.025
blastocyst growth GO:0001832 23 0.024
leukocyte proliferation GO:0070661 172 0.024
anion transport GO:0006820 177 0.024
production of molecular mediator of immune response GO:0002440 103 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
multicellular organismal reproductive behavior GO:0033057 23 0.024
metanephric distal convoluted tubule development GO:0072221 5 0.024
peripheral nervous system neuron development GO:0048935 9 0.024
regulation of heart contraction GO:0008016 77 0.024
thalamus development GO:0021794 11 0.024
catecholamine transport GO:0051937 21 0.024
regulation of renal sodium excretion GO:0035813 3 0.024
nephron development GO:0072006 109 0.024
regulation of cell activation GO:0050865 289 0.024
central nervous system segmentation GO:0035283 3 0.024
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
spinal cord motor neuron cell fate specification GO:0021520 13 0.024
cardiac cell fate determination GO:0060913 2 0.024
folic acid containing compound metabolic process GO:0006760 3 0.023
regulation of cell division GO:0051302 76 0.023
establishment or maintenance of cell polarity GO:0007163 86 0.023
proprioception involved in equilibrioception GO:0051355 1 0.023
protein maturation GO:0051604 176 0.023
hydrogen transport GO:0006818 35 0.023
regulation of muscle contraction GO:0006937 49 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
fear response GO:0042596 33 0.023
regulation of interleukin 1 beta production GO:0032651 25 0.023
regulation of catecholamine secretion GO:0050433 12 0.023
trophoblast giant cell differentiation GO:0060707 15 0.023
regulation of myeloid leukocyte differentiation GO:0002761 58 0.023
small molecule biosynthetic process GO:0044283 132 0.023
distal convoluted tubule development GO:0072025 5 0.023
metanephric nephron tubule development GO:0072234 16 0.023
ventricular cardiac muscle tissue development GO:0003229 38 0.023
myeloid cell differentiation GO:0030099 233 0.023
mrna transcription GO:0009299 4 0.023
mesoderm development GO:0007498 100 0.022
negative regulation of inflammatory response GO:0050728 61 0.022
neuron projection guidance GO:0097485 141 0.022
detection of stimulus involved in sensory perception GO:0050906 44 0.022
regulation of blood pressure GO:0008217 93 0.022
meiotic cell cycle GO:0051321 122 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
Mouse
pancreatic pp cell differentiation GO:0003312 2 0.022
l amino acid transport GO:0015807 32 0.022
multicellular organismal aging GO:0010259 24 0.022
neural tube development GO:0021915 160 0.022
response to acid chemical GO:0001101 111 0.022
negative regulation of multi organism process GO:0043901 68 0.022
proton transport GO:0015992 35 0.022
regulation of interleukin 1 alpha production GO:0032650 4 0.022
cerebellar cortex development GO:0021695 48 0.022
metanephric macula densa development GO:0072227 1 0.022
heart morphogenesis GO:0003007 178 0.022
nose development GO:0043584 12 0.021
pallium development GO:0021543 120 0.021

Pde6b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.811
Human
disease of anatomical entity DOID:7 0 0.811
Human
eye and adnexa disease DOID:1492 0 0.811
Human
nervous system disease DOID:863 0 0.811
Human
eye disease DOID:5614 0 0.811
Human
retinal disease DOID:5679 0 0.582
Human
retinal degeneration DOID:8466 0 0.582
Human
retinitis pigmentosa DOID:10584 0 0.582
Human
night blindness DOID:8499 0 0.028
Human