Mus musculus

56 known processes

Lgals1

lectin, galactose binding, soluble 1

(Aliases: Galbp,L14,L-14.5,galectin-1,Gal-1,AA410090,Lect14)

Lgals1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane raft assembly GO:0001765 3 0.582
integrin biosynthetic process GO:0045112 1 0.497
cation homeostasis GO:0055080 212 0.497
regulation of integrin biosynthetic process GO:0045113 1 0.464
regulation of neuronal synaptic plasticity GO:0048168 30 0.387
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.372
cation transport GO:0006812 399 0.304
membrane organization GO:0061024 245 0.295
regulation of neutrophil apoptotic process GO:0033029 1 0.285
positive regulation of neutrophil apoptotic process GO:0033031 1 0.248
metal ion homeostasis GO:0055065 189 0.243
cellular response to acid chemical GO:0071229 68 0.201
cellular metal ion homeostasis GO:0006875 151 0.200
engulfment of apoptotic cell GO:0043652 3 0.189
positive regulation of peptide secretion GO:0002793 33 0.178
protein maturation GO:0051604 176 0.172
cellular homeostasis GO:0019725 240 0.168
calcium ion homeostasis GO:0055074 127 0.161
fibrinolysis GO:0042730 3 0.159
regulation of body fluid levels GO:0050878 162 0.159
regulation of vesicle mediated transport GO:0060627 139 0.153
Mouse
organic acid transport GO:0015849 101 0.148
negative regulation of cellular protein metabolic process GO:0032269 247 0.140
synaptic transmission GO:0007268 329 0.138
regulation of synaptic plasticity GO:0048167 87 0.118
peptide secretion GO:0002790 114 0.111
cellular chemical homeostasis GO:0055082 215 0.105
myosin filament organization GO:0031033 3 0.105
peptide transport GO:0015833 133 0.102
coagulation GO:0050817 78 0.099
regulation of binding GO:0051098 111 0.095
regulation of secretion GO:0051046 274 0.095
phagocytosis GO:0006909 66 0.094
multi multicellular organism process GO:0044706 109 0.091
striated muscle tissue development GO:0014706 293 0.090
Zebrafish
protein processing GO:0016485 163 0.088
oxidation reduction process GO:0055114 342 0.087
muscle tissue development GO:0060537 308 0.086
Zebrafish
long chain fatty acid transport GO:0015909 15 0.085
response to acid chemical GO:0001101 111 0.084
blood coagulation GO:0007596 76 0.084
muscle contraction GO:0006936 101 0.080
regulation of hydrolase activity GO:0051336 246 0.077
divalent metal ion transport GO:0070838 172 0.076
anion transport GO:0006820 177 0.076
positive regulation of secretion GO:0051047 130 0.075
regulation of peptide transport GO:0090087 91 0.073
muscle system process GO:0003012 141 0.071
glycosyl compound metabolic process GO:1901657 246 0.069
cellular ion homeostasis GO:0006873 165 0.069
actin cytoskeleton organization GO:0030036 220 0.069
negative regulation of phagocytosis GO:0050765 4 0.068
negative regulation of peptidase activity GO:0010466 46 0.067
cellular calcium ion homeostasis GO:0006874 119 0.066
hemostasis GO:0007599 78 0.066
ion transmembrane transport GO:0034220 361 0.065
neutrophil apoptotic process GO:0001781 3 0.063
negative regulation of protein metabolic process GO:0051248 282 0.062
lipid transport GO:0006869 98 0.062
nitrogen compound transport GO:0071705 271 0.061
endocytosis GO:0006897 168 0.060
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.059
carboxylic acid transport GO:0046942 100 0.059
regulation of peptidase activity GO:0052547 96 0.059
organic anion transport GO:0015711 137 0.055
plasma membrane organization GO:0007009 90 0.054
regulation of peptide secretion GO:0002791 77 0.053
nucleoside triphosphate metabolic process GO:0009141 230 0.053
inflammatory cell apoptotic process GO:0006925 11 0.052
transmembrane transport GO:0055085 412 0.051
cellular response to antibiotic GO:0071236 4 0.050
negative regulation of protein processing GO:0010955 79 0.050
regulation of homeostatic process GO:0032844 182 0.049
endomembrane system organization GO:0010256 147 0.049
extracellular matrix organization GO:0030198 147 0.048
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.047
t cell mediated immunity GO:0002456 50 0.047
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.046
regulation of integrin mediated signaling pathway GO:2001044 8 0.045
divalent inorganic cation homeostasis GO:0072507 138 0.045
t cell activation GO:0042110 289 0.044
apoptotic cell clearance GO:0043277 17 0.043
regulation of protein maturation GO:1903317 96 0.042
neutrophil homeostasis GO:0001780 7 0.042
cell chemotaxis GO:0060326 81 0.041
positive regulation of cell death GO:0010942 224 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
extracellular structure organization GO:0043062 148 0.041
Mouse
monocarboxylic acid transport GO:0015718 44 0.041
skeletal muscle organ development GO:0060538 163 0.041
Zebrafish
positive regulation of binding GO:0051099 49 0.040
actomyosin structure organization GO:0031032 56 0.038
circulatory system process GO:0003013 197 0.037
regulation of cell cycle process GO:0010564 160 0.037
leukocyte migration GO:0050900 124 0.037
amide transport GO:0042886 138 0.036
chronological cell aging GO:0001300 1 0.035
divalent inorganic cation transport GO:0072511 178 0.035
nucleoside triphosphate catabolic process GO:0009143 205 0.034
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.034
regulation of endocytosis GO:0030100 69 0.034
Mouse
learning or memory GO:0007611 148 0.034
response to muscle stretch GO:0035994 1 0.034
regulation of actin filament based process GO:0032970 99 0.034
cellular response to oxidative stress GO:0034599 76 0.033
macromolecule catabolic process GO:0009057 281 0.032
protein heterotetramerization GO:0051290 4 0.032
cognition GO:0050890 149 0.032
cellular water homeostasis GO:0009992 2 0.031
regulation of mitotic cell cycle phase transition GO:1901990 73 0.031
striated muscle myosin thick filament assembly GO:0071688 1 0.031
ribose phosphate metabolic process GO:0019693 291 0.030
early endosome to late endosome transport GO:0045022 2 0.030
i kappab kinase nf kappab signaling GO:0007249 85 0.029
Human
positive regulation of programmed cell death GO:0043068 218 0.029
myosin filament assembly GO:0031034 2 0.029
positive regulation of cell cycle process GO:0090068 61 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.028
immune effector process GO:0002252 321 0.027
mitotic cell cycle process GO:1903047 159 0.027
positive regulation of vesicle fusion GO:0031340 2 0.027
membrane raft organization GO:0031579 5 0.027
response to vitamin a GO:0033189 1 0.026
negative regulation of cell motility GO:2000146 61 0.026
response to osmotic stress GO:0006970 21 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.025
regulation of cell cycle GO:0051726 281 0.025
sequestering of calcium ion GO:0051208 18 0.025
long chain fatty acid import GO:0044539 2 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
integrin mediated signaling pathway GO:0007229 27 0.024
regulation of cell motility GO:2000145 236 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
Mouse
regulation of muscle system process GO:0090257 80 0.024
connective tissue development GO:0061448 179 0.024
lymphocyte proliferation GO:0046651 164 0.024
regulation of protein kinase activity GO:0045859 232 0.024
neuromuscular process GO:0050905 99 0.023
ossification GO:0001503 216 0.023
detection of muscle stretch GO:0035995 1 0.023
cell type specific apoptotic process GO:0097285 268 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
muscle fiber development GO:0048747 76 0.022
Zebrafish
membrane invagination GO:0010324 17 0.022
alpha beta t cell differentiation GO:0046632 69 0.022
organic hydroxy compound transport GO:0015850 93 0.022
sequestering of metal ion GO:0051238 19 0.022
regulation of protein processing GO:0070613 96 0.022
development of primary sexual characteristics GO:0045137 143 0.022
negative regulation of endocytosis GO:0045806 12 0.022
Mouse
regulation of transferase activity GO:0051338 263 0.021
apoptotic signaling pathway GO:0097190 306 0.021
regulation of cell projection organization GO:0031344 206 0.021
striated muscle cell development GO:0055002 125 0.021
Zebrafish
small gtpase mediated signal transduction GO:0007264 97 0.021
leukocyte chemotaxis GO:0030595 69 0.021
regulation of hemostasis GO:1900046 28 0.020
negative regulation of protein maturation GO:1903318 79 0.020
l ascorbic acid metabolic process GO:0019852 4 0.020
neurotransmitter transport GO:0006836 76 0.020
g1 s transition of mitotic cell cycle GO:0000082 57 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
regulation of heart rate by chemical signal GO:0003062 4 0.020
regulation of ion transport GO:0043269 215 0.020
regulation of cell shape GO:0008360 39 0.020
lymphocyte differentiation GO:0030098 242 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
cardiac muscle tissue development GO:0048738 130 0.020
negative regulation of proteolysis GO:0045861 74 0.020
negative regulation of blood coagulation GO:0030195 11 0.019
negative regulation of cell migration GO:0030336 59 0.019
regulation of system process GO:0044057 200 0.019
positive regulation of cell cycle phase transition GO:1901989 17 0.019
multi organism behavior GO:0051705 62 0.019
acetylcholine transport GO:0015870 2 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
regulation of endopeptidase activity GO:0052548 89 0.019
response to inorganic substance GO:0010035 96 0.019
arachidonic acid secretion GO:0050482 8 0.018
heterocycle catabolic process GO:0046700 280 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
circadian sleep wake cycle rem sleep GO:0042747 1 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.018
regulation of intracellular transport GO:0032386 159 0.018
negative regulation of hydrolase activity GO:0051346 71 0.018
calcium ion transport GO:0006816 159 0.018
myeloid cell differentiation GO:0030099 233 0.017
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.017
negative regulation of molecular function GO:0044092 258 0.017
cholesterol transport GO:0030301 38 0.017
response to extracellular stimulus GO:0009991 127 0.017
forebrain development GO:0030900 302 0.017
collagen fibril organization GO:0030199 32 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
nucleoside metabolic process GO:0009116 246 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
cellular response to abiotic stimulus GO:0071214 56 0.016
regulation of transmembrane transport GO:0034762 128 0.016
microtubule based process GO:0007017 236 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
regulation of proteolysis GO:0030162 164 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
wound healing GO:0042060 157 0.016
Zebrafish
regulation of cell migration GO:0030334 219 0.016
cellular ketone metabolic process GO:0042180 84 0.016
positive regulation of mitotic cell cycle GO:0045931 41 0.016
chemotaxis GO:0006935 247 0.016
protein oligomerization GO:0051259 67 0.016
glycoprotein metabolic process GO:0009100 116 0.016
water homeostasis GO:0030104 27 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.015
chloride transmembrane transport GO:1902476 24 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
cytoplasmic transport GO:0016482 234 0.015
response to oxidative stress GO:0006979 123 0.015
regulation of cellular component size GO:0032535 121 0.015
response to nutrient levels GO:0031667 109 0.015
neural precursor cell proliferation GO:0061351 121 0.015
skeletal system development GO:0001501 356 0.015
Mouse
bone development GO:0060348 120 0.015
cytokinetic process GO:0032506 2 0.015
cardiac muscle contraction GO:0060048 32 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
sensory organ morphogenesis GO:0090596 242 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
protein localization to plasma membrane GO:0072659 57 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
negative regulation of protein modification process GO:0031400 163 0.014
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.014
prostate gland development GO:0030850 48 0.014
sensory perception GO:0007600 245 0.013
protein localization to membrane GO:0072657 108 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
protein heterooligomerization GO:0051291 14 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
response to calcium ion GO:0051592 20 0.013
cell volume homeostasis GO:0006884 9 0.013
male gonad development GO:0008584 88 0.013
wnt signaling pathway GO:0016055 188 0.013
nucleotide metabolic process GO:0009117 332 0.013
water soluble vitamin biosynthetic process GO:0042364 3 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
organelle assembly GO:0070925 177 0.013
cell growth GO:0016049 130 0.013
actin cytoskeleton reorganization GO:0031532 21 0.013
cell matrix adhesion GO:0007160 68 0.013
gonad development GO:0008406 141 0.013
myeloid cell homeostasis GO:0002262 114 0.013
platelet activation GO:0030168 40 0.012
negative regulation of protein transport GO:0051224 46 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
actin filament organization GO:0007015 113 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
epithelial cell development GO:0002064 159 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
regulation of cell cycle g1 s phase transition GO:1902806 35 0.012
fatty acid transport GO:0015908 28 0.012
regulation of lamellipodium morphogenesis GO:2000392 1 0.012
release of sequestered calcium ion into cytosol GO:0051209 42 0.012
negative regulation of neuron death GO:1901215 98 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
regulation of coagulation GO:0050818 31 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
small molecule biosynthetic process GO:0044283 132 0.012
myoblast differentiation GO:0045445 52 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
respiratory tube development GO:0030323 167 0.012
t cell proliferation GO:0042098 120 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
peptide hormone secretion GO:0030072 109 0.011
ras protein signal transduction GO:0007265 77 0.011
dna metabolic process GO:0006259 303 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
atp metabolic process GO:0046034 75 0.011
ketone catabolic process GO:0042182 3 0.011
fatty acid derivative transport GO:1901571 14 0.011
regulation of neuron death GO:1901214 134 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
muscle cell differentiation GO:0042692 261 0.011
regulation of organelle organization GO:0033043 289 0.011
intestinal absorption GO:0050892 13 0.011
protein localization to organelle GO:0033365 185 0.011
membrane assembly GO:0071709 12 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
regulation of membrane potential GO:0042391 192 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
inner ear morphogenesis GO:0042472 101 0.011
epithelial cell morphogenesis GO:0003382 41 0.011
protein catabolic process GO:0030163 221 0.011
hormone secretion GO:0046879 128 0.011
skeletal muscle fiber development GO:0048741 58 0.011
Zebrafish
regulation of protein catabolic process GO:0042176 108 0.011
lipid localization GO:0010876 126 0.011
negative regulation of hemostasis GO:1900047 11 0.011
regulation of hormone levels GO:0010817 211 0.011
mitotic cytokinesis GO:0000281 4 0.011
regulation of cell substrate adhesion GO:0010810 73 0.010
response to metal ion GO:0010038 47 0.010
negative regulation of endopeptidase activity GO:0010951 44 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
cardiac muscle cell differentiation GO:0055007 69 0.010
response to organonitrogen compound GO:0010243 246 0.010
substantia nigra development GO:0021762 2 0.010
carbohydrate metabolic process GO:0005975 230 0.010
peripheral nervous system axon regeneration GO:0014012 2 0.010
activation of cdc42 gtpase activity GO:0032864 2 0.010
cardiac ventricle development GO:0003231 83 0.010
platelet aggregation GO:0070527 20 0.010
regulation of phospholipid biosynthetic process GO:0071071 3 0.010
positive regulation of muscle cell differentiation GO:0051149 39 0.010

Lgals1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.096
bone disease DOID:0080001 0 0.096
disease of anatomical entity DOID:7 0 0.096
musculoskeletal system disease DOID:17 0 0.096
connective tissue disease DOID:65 0 0.096
disease of metabolism DOID:0014667 0 0.057
osteochondrodysplasia DOID:2256 0 0.035
nervous system disease DOID:863 0 0.034
primary immunodeficiency disease DOID:612 0 0.023
immune system disease DOID:2914 0 0.023
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
acquired metabolic disease DOID:0060158 0 0.011
epilepsy syndrome DOID:1826 0 0.010
central nervous system disease DOID:331 0 0.010
brain disease DOID:936 0 0.010