Mus musculus

0 known processes

Thoc6

THO complex 6 homolog (Drosophila)

(Aliases: MGC109691,MGC107304,F830014G06Rik,Wdr58)

Thoc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.119
chromatin modification GO:0016568 187 0.075
iron sulfur cluster assembly GO:0016226 3 0.066
chromatin organization GO:0006325 206 0.060
cellular amino acid metabolic process GO:0006520 103 0.057
cellular response to dna damage stimulus GO:0006974 207 0.057
covalent chromatin modification GO:0016569 163 0.054
regulation of cell cycle GO:0051726 281 0.050
histone modification GO:0016570 159 0.050
protein modification by small protein conjugation GO:0032446 187 0.049
nucleoside triphosphate metabolic process GO:0009141 230 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
rna processing GO:0006396 105 0.045
leukocyte differentiation GO:0002521 342 0.042
regulation of organelle organization GO:0033043 289 0.041
nucleoside metabolic process GO:0009116 246 0.041
protein modification by small protein conjugation or removal GO:0070647 207 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
rna interference GO:0016246 2 0.038
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
macromolecule catabolic process GO:0009057 281 0.038
cellular homeostasis GO:0019725 240 0.038
germ cell development GO:0007281 185 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
aromatic compound catabolic process GO:0019439 286 0.035
regulation of apoptotic signaling pathway GO:2001233 197 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
regulation of transferase activity GO:0051338 263 0.033
gene silencing GO:0016458 38 0.033
positive regulation of protein modification process GO:0031401 299 0.033
regulation of cell cycle process GO:0010564 160 0.033
lymphocyte differentiation GO:0030098 242 0.033
apoptotic signaling pathway GO:0097190 306 0.030
cellular ketone metabolic process GO:0042180 84 0.030
spermatogenesis GO:0007283 284 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
microtubule cytoskeleton organization GO:0000226 157 0.028
amine metabolic process GO:0009308 45 0.027
protein ubiquitination GO:0016567 171 0.027
mrna metabolic process GO:0016071 84 0.026
response to organic cyclic compound GO:0014070 198 0.026
organic cyclic compound catabolic process GO:1901361 295 0.025
t cell activation GO:0042110 289 0.025
nucleotide metabolic process GO:0009117 332 0.025
cellular amine metabolic process GO:0044106 44 0.025
cell division GO:0051301 120 0.024
regulation of cell activation GO:0050865 289 0.024
positive regulation of cell death GO:0010942 224 0.024
peptidyl amino acid modification GO:0018193 336 0.023
ras protein signal transduction GO:0007265 77 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
negative regulation of organelle organization GO:0010639 90 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
cellular protein catabolic process GO:0044257 155 0.022
response to oxidative stress GO:0006979 123 0.022
regulation of cell division GO:0051302 76 0.022
organelle fission GO:0048285 170 0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.022
mitotic cell cycle process GO:1903047 159 0.022
positive regulation of cell activation GO:0050867 158 0.022
skeletal system development GO:0001501 356 0.022
myosin filament assembly GO:0031034 2 0.021
positive regulation of cell development GO:0010720 237 0.021
purine containing compound metabolic process GO:0072521 311 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
rna splicing via transesterification reactions GO:0000375 43 0.021
negative regulation of cell cycle GO:0045786 123 0.021
negative regulation of cell cycle process GO:0010948 69 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
cellular protein complex assembly GO:0043623 116 0.020
heterocycle catabolic process GO:0046700 280 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
blastocyst development GO:0001824 80 0.019
wnt signaling pathway GO:0016055 188 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
microtubule based process GO:0007017 236 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
leukocyte proliferation GO:0070661 172 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.018
gonad development GO:0008406 141 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
nuclear division GO:0000280 158 0.018
digestive system development GO:0055123 200 0.018
b cell activation GO:0042113 161 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
transmembrane transport GO:0055085 412 0.018
respiratory tube development GO:0030323 167 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
nitrogen compound transport GO:0071705 271 0.017
Human
cellular response to lipid GO:0071396 145 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
nucleobase containing compound transport GO:0015931 27 0.017
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.017
cellular chemical homeostasis GO:0055082 215 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
stem cell differentiation GO:0048863 268 0.016
regulation of t cell activation GO:0050863 170 0.016
mitotic cell cycle GO:0000278 195 0.016
response to acid chemical GO:0001101 111 0.016
protein catabolic process GO:0030163 221 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
regionalization GO:0003002 337 0.016
lung development GO:0030324 164 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
protein processing GO:0016485 163 0.016
meiotic nuclear division GO:0007126 115 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
male gamete generation GO:0048232 285 0.016
regulation of cell projection organization GO:0031344 206 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
metal ion homeostasis GO:0055065 189 0.015
cation homeostasis GO:0055080 212 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
t cell differentiation GO:0030217 174 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
positive regulation of organelle organization GO:0010638 128 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
mrna processing GO:0006397 63 0.014
peptidyl lysine modification GO:0018205 77 0.014
gland development GO:0048732 330 0.014
regulation of cell migration GO:0030334 219 0.014
regulation of mapk cascade GO:0043408 248 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
membrane organization GO:0061024 245 0.014
stem cell development GO:0048864 219 0.014
cellular ion homeostasis GO:0006873 165 0.014
regulation of rna splicing GO:0043484 37 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
fertilization GO:0009566 127 0.014
digestive tract development GO:0048565 190 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
endocytosis GO:0006897 168 0.014
dna repair GO:0006281 107 0.014
organophosphate catabolic process GO:0046434 232 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
positive regulation of transferase activity GO:0051347 167 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
striated muscle tissue development GO:0014706 293 0.014
positive regulation of nervous system development GO:0051962 221 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
lymphocyte proliferation GO:0046651 164 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.013
camera type eye development GO:0043010 266 0.013
regulation of cell motility GO:2000145 236 0.013
cytoplasmic transport GO:0016482 234 0.013
Human
regulation of homeostatic process GO:0032844 182 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
protein maturation GO:0051604 176 0.013
positive regulation of growth GO:0045927 104 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
meiotic cell cycle GO:0051321 122 0.013
immune effector process GO:0002252 321 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
neural tube development GO:0021915 160 0.012
negative regulation of immune system process GO:0002683 209 0.012
striated muscle cell development GO:0055002 125 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
cytokine production GO:0001816 319 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
mapk cascade GO:0000165 281 0.012
multicellular organism growth GO:0035264 161 0.012
regulation of neuron differentiation GO:0045664 281 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
locomotory behavior GO:0007626 195 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of mrna processing GO:0050684 41 0.012
myeloid cell differentiation GO:0030099 233 0.011
cell type specific apoptotic process GO:0097285 268 0.011
forebrain development GO:0030900 302 0.011
response to organonitrogen compound GO:0010243 246 0.011
organelle assembly GO:0070925 177 0.011
positive regulation of immature t cell proliferation GO:0033091 4 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
blood vessel morphogenesis GO:0048514 285 0.011
t cell proliferation GO:0042098 120 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
maintenance of location GO:0051235 89 0.011
skeletal system morphogenesis GO:0048705 203 0.011
muscle tissue development GO:0060537 308 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
gene silencing by rna GO:0031047 19 0.011
regulation of membrane potential GO:0042391 192 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of t cell proliferation GO:0042129 92 0.011
protein methylation GO:0006479 81 0.011
regulation of mrna splicing via spliceosome GO:0048024 32 0.011
homeostasis of number of cells GO:0048872 210 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
retina development in camera type eye GO:0060041 119 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
t cell differentiation in thymus GO:0033077 77 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
cellular response to acid chemical GO:0071229 68 0.011
multi organism behavior GO:0051705 62 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
regulation of feeding behavior GO:0060259 3 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
cation transmembrane transport GO:0098655 266 0.010
purine containing compound catabolic process GO:0072523 213 0.010
positive regulation of cell cycle process GO:0090068 61 0.010
nucleoside catabolic process GO:0009164 206 0.010
regulation of protein complex assembly GO:0043254 83 0.010
metallo sulfur cluster assembly GO:0031163 3 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
compound eye development GO:0048749 1 0.010
pharynx development GO:0060465 1 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
respiratory system development GO:0060541 190 0.010
endomembrane system organization GO:0010256 147 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010

Thoc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
central nervous system disease DOID:331 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.013
neurodegenerative disease DOID:1289 0 0.013