Mus musculus

98 known processes

Thoc5

THO complex 5

(Aliases: MGC49541,Sgk2,Fmip,1700060C24Rik,A430085L24Rik,PK1.3)

Thoc5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aromatic compound catabolic process GO:0019439 286 0.158
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.099
cellular response to dna damage stimulus GO:0006974 207 0.088
mrna processing GO:0006397 63 0.082
cellular amino acid metabolic process GO:0006520 103 0.078
maturation of 5 8s rrna GO:0000460 1 0.075
heterocycle catabolic process GO:0046700 280 0.069
rna processing GO:0006396 105 0.065
cellular ketone metabolic process GO:0042180 84 0.064
amine metabolic process GO:0009308 45 0.059
ribose phosphate metabolic process GO:0019693 291 0.058
cytoplasmic transport GO:0016482 234 0.057
cellular nitrogen compound catabolic process GO:0044270 280 0.055
purine containing compound metabolic process GO:0072521 311 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
microtubule cytoskeleton organization GO:0000226 157 0.051
regulation of cellular amine metabolic process GO:0033238 20 0.048
nucleotide catabolic process GO:0009166 217 0.048
nucleocytoplasmic transport GO:0006913 139 0.046
cellular amine metabolic process GO:0044106 44 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.044
peptidyl amino acid modification GO:0018193 336 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
purine nucleoside triphosphate catabolic process GO:0009146 203 0.042
dna metabolic process GO:0006259 303 0.041
regulation of cell cycle GO:0051726 281 0.040
microtubule based process GO:0007017 236 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
purine ribonucleoside catabolic process GO:0046130 205 0.037
protein localization to organelle GO:0033365 185 0.036
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.036
organic cyclic compound catabolic process GO:1901361 295 0.034
endocytosis GO:0006897 168 0.034
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
intracellular protein transport GO:0006886 204 0.032
purine nucleotide catabolic process GO:0006195 211 0.029
nuclear transport GO:0051169 139 0.029
organelle assembly GO:0070925 177 0.029
nucleoside catabolic process GO:0009164 206 0.029
regulation of cytoplasmic transport GO:1903649 112 0.029
regulation of establishment of protein localization GO:0070201 181 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
organophosphate catabolic process GO:0046434 232 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.028
ribonucleoside catabolic process GO:0042454 206 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
apoptotic signaling pathway GO:0097190 306 0.027
nuclear division GO:0000280 158 0.027
maintenance of location GO:0051235 89 0.027
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.027
regulation of intracellular transport GO:0032386 159 0.026
regulation of protein localization GO:0032880 231 0.026
mrna metabolic process GO:0016071 84 0.025
regulation of organelle organization GO:0033043 289 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
neuron apoptotic process GO:0051402 142 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
blastocyst development GO:0001824 80 0.024
chromatin organization GO:0006325 206 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
organelle fission GO:0048285 170 0.023
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.023
mitotic cell cycle process GO:1903047 159 0.023
ribonucleotide catabolic process GO:0009261 208 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
regulation of neuron death GO:1901214 134 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
purine containing compound catabolic process GO:0072523 213 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
nucleoside metabolic process GO:0009116 246 0.022
dna repair GO:0006281 107 0.021
rna splicing GO:0008380 54 0.021
intracellular mrna localization GO:0008298 4 0.021
translation GO:0006412 93 0.021
protein localization to nucleus GO:0034504 121 0.021
macromolecule catabolic process GO:0009057 281 0.020
cytokine production GO:0001816 319 0.020
negative regulation of neuron death GO:1901215 98 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
mitotic cell cycle GO:0000278 195 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
trna wobble uridine modification GO:0002098 2 0.019
meiotic nuclear division GO:0007126 115 0.018
germ cell development GO:0007281 185 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
nucleotide metabolic process GO:0009117 332 0.018
immune effector process GO:0002252 321 0.018
carbohydrate metabolic process GO:0005975 230 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
positive regulation of cell death GO:0010942 224 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
skeletal system development GO:0001501 356 0.017
regulation of cell activation GO:0050865 289 0.017
regulation of protein transport GO:0051223 163 0.017
cell type specific apoptotic process GO:0097285 268 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
ras protein signal transduction GO:0007265 77 0.016
covalent chromatin modification GO:0016569 163 0.016
regulation of cytokine production GO:0001817 266 0.016
muscle cell differentiation GO:0042692 261 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
response to light stimulus GO:0009416 135 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
substantia nigra development GO:0021762 2 0.015
regulation of cell projection organization GO:0031344 206 0.015
neuron death GO:0070997 154 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
mrna splicing via spliceosome GO:0000398 43 0.015
single organism nuclear import GO:1902593 95 0.015
protein targeting GO:0006605 143 0.015
peptidyl lysine modification GO:0018205 77 0.014
development of primary sexual characteristics GO:0045137 143 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.014
response to radiation GO:0009314 165 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
endomembrane system organization GO:0010256 147 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
nuclear import GO:0051170 95 0.014
negative regulation of cell cycle GO:0045786 123 0.014
fertilization GO:0009566 127 0.014
regulation of mrna metabolic process GO:1903311 43 0.014
terminal button organization GO:0072553 3 0.013
protein acylation GO:0043543 64 0.013
stem cell differentiation GO:0048863 268 0.013
membrane organization GO:0061024 245 0.013
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.013
hatching GO:0035188 4 0.013
mapk cascade GO:0000165 281 0.013
leukocyte differentiation GO:0002521 342 0.013
multicellular organismal signaling GO:0035637 91 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
ncrna processing GO:0034470 26 0.012
response to acid chemical GO:0001101 111 0.012
cell adhesion GO:0007155 329 0.012
regulation of mrna processing GO:0050684 41 0.012
t cell activation GO:0042110 289 0.012
regulation of protein targeting GO:1903533 61 0.012
regulation of transposition GO:0010528 2 0.012
protein import into nucleus GO:0006606 95 0.012
gonad development GO:0008406 141 0.012
protein import GO:0017038 101 0.012
anatomical structure homeostasis GO:0060249 145 0.012
meiotic cell cycle GO:0051321 122 0.012
positive regulation of cell activation GO:0050867 158 0.012
regulation of cellular response to stress GO:0080135 159 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
cellular response to lipid GO:0071396 145 0.012
negative regulation of molecular function GO:0044092 258 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.011
regulation of transferase activity GO:0051338 263 0.011
multicellular organism growth GO:0035264 161 0.011
regulation of t cell activation GO:0050863 170 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
spermatogenesis GO:0007283 284 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
organelle localization GO:0051640 179 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
lymphocyte differentiation GO:0030098 242 0.011
positive regulation of protein modification process GO:0031401 299 0.011
muscle tissue development GO:0060537 308 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
blood vessel morphogenesis GO:0048514 285 0.011
response to organonitrogen compound GO:0010243 246 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
protein dna complex subunit organization GO:0071824 28 0.011
homeostasis of number of cells GO:0048872 210 0.011
protein catabolic process GO:0030163 221 0.011
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
receptor mediated endocytosis GO:0006898 51 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
transmission of nerve impulse GO:0019226 76 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
meiotic cell cycle process GO:1903046 77 0.011
glycoprotein biosynthetic process GO:0009101 89 0.010
regionalization GO:0003002 337 0.010
regulation of neuron projection development GO:0010975 169 0.010
internal peptidyl lysine acetylation GO:0018393 42 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
response to organic cyclic compound GO:0014070 198 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
action potential GO:0001508 78 0.010

Thoc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.024
sensory system disease DOID:0050155 0 0.024
disease of anatomical entity DOID:7 0 0.024
eye and adnexa disease DOID:1492 0 0.024
nervous system disease DOID:863 0 0.024
eye disease DOID:5614 0 0.024
retinal degeneration DOID:8466 0 0.016