Mus musculus

57 known processes

Wnk1

WNK lysine deficient protein kinase 1

(Aliases: Hsn2,Prkwnk1,MGC175896,mKIAA0344,MGC175898,EG406236,6430573H23Rik)

Wnk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.242
negative regulation of protein metabolic process GO:0051248 282 0.213
Rat
macromolecule catabolic process GO:0009057 281 0.180
negative regulation of cellular protein metabolic process GO:0032269 247 0.153
Rat
ribonucleoside metabolic process GO:0009119 245 0.148
gene silencing by mirna GO:0035195 10 0.141
purine containing compound metabolic process GO:0072521 311 0.140
organelle assembly GO:0070925 177 0.140
male gamete generation GO:0048232 285 0.138
digestive system development GO:0055123 200 0.130
purine ribonucleoside metabolic process GO:0046128 241 0.129
habituation GO:0046959 3 0.128
stem cell differentiation GO:0048863 268 0.127
olfactory learning GO:0008355 2 0.123
organic cyclic compound catabolic process GO:1901361 295 0.122
purine nucleoside metabolic process GO:0042278 241 0.112
organonitrogen compound catabolic process GO:1901565 264 0.111
cellularization GO:0007349 1 0.108
glycosyl compound metabolic process GO:1901657 246 0.103
nucleobase containing small molecule metabolic process GO:0055086 352 0.102
aromatic compound catabolic process GO:0019439 286 0.099
cellular nitrogen compound catabolic process GO:0044270 280 0.095
mitotic cell cycle process GO:1903047 159 0.090
nucleoside triphosphate metabolic process GO:0009141 230 0.089
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.086
microtubule cytoskeleton organization GO:0000226 157 0.085
apical constriction GO:0003383 4 0.084
protein processing GO:0016485 163 0.080
purine nucleotide metabolic process GO:0006163 302 0.080
ribonucleoside catabolic process GO:0042454 206 0.080
chromatin organization GO:0006325 206 0.080
regulation of protein localization GO:0032880 231 0.078
posttranscriptional regulation of gene expression GO:0010608 155 0.077
germ cell development GO:0007281 185 0.076
ribonucleotide metabolic process GO:0009259 291 0.076
nucleoside metabolic process GO:0009116 246 0.076
cellular amine metabolic process GO:0044106 44 0.074
nuclear division GO:0000280 158 0.074
cellular ketone metabolic process GO:0042180 84 0.073
purine ribonucleoside catabolic process GO:0046130 205 0.073
mitotic cell cycle GO:0000278 195 0.072
cellular macromolecule catabolic process GO:0044265 206 0.071
cellular amino acid metabolic process GO:0006520 103 0.070
purine nucleoside catabolic process GO:0006152 205 0.070
cellular response to dna damage stimulus GO:0006974 207 0.069
purine ribonucleotide metabolic process GO:0009150 290 0.069
nucleoside phosphate catabolic process GO:1901292 222 0.068
meiotic cell cycle GO:0051321 122 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.067
ribose phosphate metabolic process GO:0019693 291 0.066
heterocycle catabolic process GO:0046700 280 0.065
cation transport GO:0006812 399 0.065
Rat
regulation of hydrolase activity GO:0051336 246 0.065
Human
nucleotide metabolic process GO:0009117 332 0.064
purine ribonucleotide catabolic process GO:0009154 208 0.064
regulation of cellular amine metabolic process GO:0033238 20 0.064
purine containing compound catabolic process GO:0072523 213 0.064
purine nucleoside triphosphate catabolic process GO:0009146 203 0.063
regulation of system process GO:0044057 200 0.062
membrane organization GO:0061024 245 0.062
digestive tract development GO:0048565 190 0.059
intracellular protein transport GO:0006886 204 0.059
stem cell development GO:0048864 219 0.059
ribonucleotide catabolic process GO:0009261 208 0.058
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.057
ossification GO:0001503 216 0.057
spermatid differentiation GO:0048515 115 0.057
ras protein signal transduction GO:0007265 77 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.056
amine metabolic process GO:0009308 45 0.056
negative regulation of intracellular signal transduction GO:1902532 167 0.056
nucleotide catabolic process GO:0009166 217 0.056
epithelial cell development GO:0002064 159 0.054
male meiosis GO:0007140 37 0.054
organophosphate catabolic process GO:0046434 232 0.054
regulation of protein kinase activity GO:0045859 232 0.054
Rat
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.053
ribonucleoside triphosphate catabolic process GO:0009203 199 0.052
glycosyl compound catabolic process GO:1901658 206 0.052
purine nucleoside triphosphate metabolic process GO:0009144 226 0.051
regulation of cell cycle process GO:0010564 160 0.051
nucleoside phosphate metabolic process GO:0006753 338 0.051
spermatid development GO:0007286 108 0.049
embryonic organ morphogenesis GO:0048562 276 0.048
apoptotic signaling pathway GO:0097190 306 0.048
organelle fission GO:0048285 170 0.048
nucleoside triphosphate catabolic process GO:0009143 205 0.047
negative regulation of cell cycle GO:0045786 123 0.046
dna metabolic process GO:0006259 303 0.046
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.046
meiotic nuclear division GO:0007126 115 0.046
regulation of cellular catabolic process GO:0031329 242 0.046
rna interference GO:0016246 2 0.046
purine nucleotide catabolic process GO:0006195 211 0.045
negative regulation of phosphorus metabolic process GO:0010563 184 0.044
Human Rat
leukocyte differentiation GO:0002521 342 0.043
regulation of cell cycle GO:0051726 281 0.043
regulation of transferase activity GO:0051338 263 0.043
Rat
cognition GO:0050890 149 0.043
translation GO:0006412 93 0.042
histone modification GO:0016570 159 0.042
regulation of response to wounding GO:1903034 189 0.042
microtubule based process GO:0007017 236 0.042
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
male meiosis i GO:0007141 16 0.041
ribonucleoprotein complex subunit organization GO:0071826 28 0.040
segmentation GO:0035282 93 0.040
regulation of kinase activity GO:0043549 249 0.039
Rat
meiosis i GO:0007127 60 0.039
oocyte axis specification GO:0007309 2 0.039
regulation of organelle organization GO:0033043 289 0.039
neuron projection guidance GO:0097485 141 0.038
Fly
circulatory system process GO:0003013 197 0.038
cell cycle switching GO:0060184 1 0.038
nucleoside catabolic process GO:0009164 206 0.038
learning or memory GO:0007611 148 0.038
regulation of proteolysis GO:0030162 164 0.037
regulation of cell migration GO:0030334 219 0.037
methylation GO:0032259 134 0.037
atp catabolic process GO:0006200 55 0.037
fat cell differentiation GO:0045444 160 0.037
gene silencing by rna GO:0031047 19 0.037
skeletal system development GO:0001501 356 0.036
gonad development GO:0008406 141 0.036
protein catabolic process GO:0030163 221 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.036
regulation of cell motility GO:2000145 236 0.036
plasma membrane organization GO:0007009 90 0.036
cellular protein catabolic process GO:0044257 155 0.036
regulation of mapk cascade GO:0043408 248 0.036
regionalization GO:0003002 337 0.035
negative regulation of protein processing GO:0010955 79 0.035
protein maturation GO:0051604 176 0.035
negative regulation of protein maturation GO:1903318 79 0.035
midgut development GO:0007494 4 0.035
axonogenesis GO:0007409 274 0.035
Fly
dna methylation GO:0006306 43 0.035
chromatin modification GO:0016568 187 0.034
small gtpase mediated signal transduction GO:0007264 97 0.034
ion transmembrane transport GO:0034220 361 0.034
Human Rat
cell substrate adhesion GO:0031589 130 0.033
response to organic cyclic compound GO:0014070 198 0.033
regulation of establishment of protein localization GO:0070201 181 0.033
actin cytoskeleton organization GO:0030036 220 0.032
protein ubiquitination GO:0016567 171 0.032
protein localization to organelle GO:0033365 185 0.032
response to growth factor GO:0070848 198 0.032
cellular homeostasis GO:0019725 240 0.032
negative regulation of molecular function GO:0044092 258 0.032
Human Rat
macromolecule methylation GO:0043414 120 0.031
regulation of cell projection organization GO:0031344 206 0.031
rna catabolic process GO:0006401 29 0.031
protein localization to plasma membrane GO:0072659 57 0.031
immune effector process GO:0002252 321 0.031
purine nucleoside monophosphate metabolic process GO:0009126 81 0.031
mrna metabolic process GO:0016071 84 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
ribonucleoside monophosphate catabolic process GO:0009158 57 0.030
wound healing GO:0042060 157 0.030
nitrogen compound transport GO:0071705 271 0.030
positive regulation of hydrolase activity GO:0051345 148 0.029
regulation of mitotic cell cycle GO:0007346 126 0.029
organelle localization GO:0051640 179 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
Human Rat
actin mediated cell contraction GO:0070252 15 0.029
stem cell maintenance GO:0019827 130 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
Human Rat
dendrite development GO:0016358 115 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
skeletal system morphogenesis GO:0048705 203 0.028
regulation of defense response GO:0031347 233 0.028
nucleocytoplasmic transport GO:0006913 139 0.028
regulation of inflammatory response GO:0050727 147 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
blastocyst development GO:0001824 80 0.028
regulation of protein processing GO:0070613 96 0.028
synaptic transmission GO:0007268 329 0.028
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.028
cellular chemical homeostasis GO:0055082 215 0.028
positive regulation of growth GO:0045927 104 0.027
mesodermal cell migration GO:0008078 4 0.027
covalent chromatin modification GO:0016569 163 0.027
limb morphogenesis GO:0035108 149 0.027
gland development GO:0048732 330 0.027
regulation of membrane potential GO:0042391 192 0.027
negative regulation of phosphorylation GO:0042326 166 0.027
Rat
oocyte construction GO:0007308 2 0.027
positive regulation of cell cycle GO:0045787 92 0.027
innate immune response GO:0045087 157 0.027
cellular response to abiotic stimulus GO:0071214 56 0.026
embryonic appendage morphogenesis GO:0035113 126 0.026
skin development GO:0043588 220 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
intracellular mrna localization GO:0008298 4 0.026
ameboidal type cell migration GO:0001667 128 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.026
sensory perception of sound GO:0007605 97 0.026
embryonic skeletal system development GO:0048706 120 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
oogenesis GO:0048477 56 0.026
cation homeostasis GO:0055080 212 0.025
meiotic cell cycle process GO:1903046 77 0.025
protein localization to membrane GO:0072657 108 0.025
regulation of cell cycle phase transition GO:1901987 77 0.025
modification dependent macromolecule catabolic process GO:0043632 133 0.025
inflammatory response GO:0006954 244 0.024
regulation of ossification GO:0030278 112 0.024
limb development GO:0060173 166 0.024
lipid biosynthetic process GO:0008610 179 0.024
positive regulation of cell death GO:0010942 224 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
Fly
regulation of protein maturation GO:1903317 96 0.024
cell adhesion GO:0007155 329 0.024
oocyte anterior posterior axis specification GO:0007314 2 0.024
regulation of protein catabolic process GO:0042176 108 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.023
lateral inhibition GO:0046331 1 0.023
cell fate commitment GO:0045165 210 0.023
female gamete generation GO:0007292 74 0.023
ribonucleoside monophosphate metabolic process GO:0009161 80 0.023
sensory perception GO:0007600 245 0.023
gtp catabolic process GO:0006184 143 0.023
development of primary sexual characteristics GO:0045137 143 0.023
muscle tissue development GO:0060537 308 0.023
striated muscle tissue development GO:0014706 293 0.023
blood vessel morphogenesis GO:0048514 285 0.023
rho protein signal transduction GO:0007266 32 0.023
digestive tract morphogenesis GO:0048546 147 0.023
positive regulation of transferase activity GO:0051347 167 0.023
fertilization GO:0009566 127 0.023
regulation of protein transport GO:0051223 163 0.023
chemotaxis GO:0006935 247 0.023
Fly
actin filament based movement GO:0030048 23 0.023
regulation of leukocyte differentiation GO:1902105 159 0.023
regulation of cellular response to stress GO:0080135 159 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.022
cell cycle checkpoint GO:0000075 47 0.022
cation transmembrane transport GO:0098655 266 0.022
Rat
cytoplasmic transport GO:0016482 234 0.022
negative regulation of cell cycle process GO:0010948 69 0.022
embryonic limb morphogenesis GO:0030326 126 0.022
regulation of vesicle mediated transport GO:0060627 139 0.022
negative regulation of protein modification process GO:0031400 163 0.022
Rat
cell type specific apoptotic process GO:0097285 268 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
regulation of cell adhesion GO:0030155 154 0.021
respiratory system development GO:0060541 190 0.021
pole plasm assembly GO:0007315 2 0.021
blood circulation GO:0008015 195 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
regulation of mitotic cell cycle phase transition GO:1901990 73 0.021
regulation of meiotic cell cycle GO:0051445 34 0.021
cellular response to organic cyclic compound GO:0071407 87 0.021
negative regulation of proteolysis GO:0045861 74 0.021
skeletal muscle organ development GO:0060538 163 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.020
metal ion homeostasis GO:0055065 189 0.020
regulation of anatomical structure size GO:0090066 178 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
cytoplasmic mrna processing body assembly GO:0033962 6 0.020
endocytosis GO:0006897 168 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
posttranscriptional gene silencing GO:0016441 10 0.020
nuclear transport GO:0051169 139 0.020
cellular response to lipid GO:0071396 145 0.020
response to radiation GO:0009314 165 0.020
divalent inorganic cation transport GO:0072511 178 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
synapse organization GO:0050808 125 0.020
learning GO:0007612 98 0.020
cellular protein complex assembly GO:0043623 116 0.020
kidney development GO:0001822 213 0.019
mitotic cytokinesis GO:0000281 4 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
cytokinetic process GO:0032506 2 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
chromatin silencing GO:0006342 15 0.019
mapk cascade GO:0000165 281 0.019
mrna catabolic process GO:0006402 22 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
negative regulation of mitotic cell cycle GO:0045930 58 0.019
leukocyte mediated immunity GO:0002443 174 0.019
regulation of translation GO:0006417 71 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
wnt signaling pathway GO:0016055 188 0.019
Fly
negative regulation of sterol transport GO:0032372 4 0.019
forebrain development GO:0030900 302 0.019
positive regulation of meiotic cell cycle GO:0051446 15 0.019
regulation of intracellular transport GO:0032386 159 0.019
regulation of mrna processing GO:0050684 41 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
transmembrane transport GO:0055085 412 0.018
Human Rat
regulation of actin filament based process GO:0032970 99 0.018
cell division GO:0051301 120 0.018
positive regulation of leukocyte differentiation GO:1902107 86 0.018
divalent metal ion transport GO:0070838 172 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.018
stem cell fate specification GO:0048866 3 0.018
renal system development GO:0072001 225 0.018
regulation of embryonic development GO:0045995 71 0.018
muscle cell differentiation GO:0042692 261 0.017
positive regulation of response to wounding GO:1903036 66 0.017
cell matrix adhesion GO:0007160 68 0.017
activation of immune response GO:0002253 138 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
Rat
multicellular organismal signaling GO:0035637 91 0.017
regulation of hormone levels GO:0010817 211 0.017
positive regulation of kinase activity GO:0033674 155 0.017
posttranscriptional gene silencing by rna GO:0035194 10 0.017
associative learning GO:0008306 61 0.017
epithelial cell morphogenesis GO:0003382 41 0.016
nuclear transcribed mrna catabolic process GO:0000956 16 0.016
oxidation reduction process GO:0055114 342 0.016
protein methylation GO:0006479 81 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of mrna catabolic process GO:0061013 6 0.016
locomotory behavior GO:0007626 195 0.016
regulation of neuron differentiation GO:0045664 281 0.016
myeloid leukocyte activation GO:0002274 83 0.016
endomembrane system organization GO:0010256 147 0.016
regulation of circadian sleep wake cycle GO:0042749 3 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
cell migration involved in gastrulation GO:0042074 13 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
positive regulation of protein modification process GO:0031401 299 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
peptidyl amino acid modification GO:0018193 336 0.016
appendage development GO:0048736 166 0.016
response to organonitrogen compound GO:0010243 246 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
microtubule based transport GO:0010970 50 0.016
regulation of neurological system process GO:0031644 22 0.016
positive regulation of necrotic cell death GO:0010940 1 0.016
calcium ion homeostasis GO:0055074 127 0.016
bone development GO:0060348 120 0.016
b cell activation GO:0042113 161 0.016
positive regulation of ossification GO:0045778 47 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
establishment of organelle localization GO:0051656 122 0.015
urogenital system development GO:0001655 261 0.015
regulation of secretion GO:0051046 274 0.015
circadian rhythm GO:0007623 114 0.015
negative regulation of mapk cascade GO:0043409 65 0.015
rna processing GO:0006396 105 0.015
response to peptide hormone GO:0043434 127 0.015
atp metabolic process GO:0046034 75 0.015
regulation of cell substrate adhesion GO:0010810 73 0.015
response to nutrient levels GO:0031667 109 0.015
positive regulation of cell development GO:0010720 237 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
response to alcohol GO:0097305 48 0.015
t cell activation GO:0042110 289 0.015
myeloid cell differentiation GO:0030099 233 0.015
regulation of body fluid levels GO:0050878 162 0.015
cell growth GO:0016049 130 0.015
sensory organ morphogenesis GO:0090596 242 0.015
sequestering of metal ion GO:0051238 19 0.015
mitochondrion transport along microtubule GO:0047497 3 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of chromatin silencing GO:0031935 2 0.015
myeloid cell homeostasis GO:0002262 114 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
sensory perception of mechanical stimulus GO:0050954 107 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of homeostatic process GO:0032844 182 0.014
calcium ion transport GO:0006816 159 0.014
establishment of vesicle localization GO:0051650 81 0.014
cell recognition GO:0008037 83 0.014
establishment of mitochondrion localization GO:0051654 4 0.014
glomerulus development GO:0032835 40 0.014
negative regulation of translational initiation GO:0045947 4 0.014
response to sterol GO:0036314 4 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
positive regulation of nervous system development GO:0051962 221 0.014
regulation of mrna metabolic process GO:1903311 43 0.014
single organism cell adhesion GO:0098602 156 0.014
tissue remodeling GO:0048771 102 0.014
neural tube development GO:0021915 160 0.014
myotube differentiation GO:0014902 105 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
anatomical structure homeostasis GO:0060249 145 0.014
regulation of ion transport GO:0043269 215 0.014
rab protein signal transduction GO:0032482 1 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
small molecule biosynthetic process GO:0044283 132 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
gene silencing GO:0016458 38 0.014
response to inorganic substance GO:0010035 96 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
cellular metal ion homeostasis GO:0006875 151 0.013
mitotic sister chromatid cohesion GO:0007064 1 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
somitogenesis GO:0001756 69 0.013
camera type eye development GO:0043010 266 0.013
cell junction assembly GO:0034329 52 0.013
i kappab kinase nf kappab signaling GO:0007249 85 0.013
maintenance of location GO:0051235 89 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
nephron development GO:0072006 109 0.013
negative regulation of peptidase activity GO:0010466 46 0.013
chromosome segregation GO:0007059 48 0.013
negative regulation of chromatin silencing GO:0031936 1 0.013
ear development GO:0043583 200 0.013
glial cell differentiation GO:0010001 131 0.013
mesoderm development GO:0007498 100 0.013
molting cycle GO:0042303 90 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
Human
multi multicellular organism process GO:0044706 109 0.013
Worm
vesicle localization GO:0051648 86 0.013
gtp metabolic process GO:0046039 144 0.013
axon guidance GO:0007411 141 0.013
Fly
establishment of protein localization to membrane GO:0090150 54 0.013
cell activation involved in immune response GO:0002263 126 0.013
gastrulation GO:0007369 116 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
negative regulation of endopeptidase activity GO:0010951 44 0.013
dna repair GO:0006281 107 0.013
transmission of nerve impulse GO:0019226 76 0.013
developmental maturation GO:0021700 193 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
dna integrity checkpoint GO:0031570 28 0.012
angiogenesis GO:0001525 201 0.012
gliogenesis GO:0042063 141 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
sulfur compound metabolic process GO:0006790 100 0.012
t cell differentiation GO:0030217 174 0.012
regulation of mrna 3 end processing GO:0031440 6 0.012
golgi to endosome transport GO:0006895 3 0.012
erbb signaling pathway GO:0038127 32 0.012
response to acid chemical GO:0001101 111 0.012
tissue homeostasis GO:0001894 115 0.012
anion transmembrane transport GO:0098656 71 0.012
Human
spindle organization GO:0007051 28 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
retina development in camera type eye GO:0060041 119 0.012
cell maturation GO:0048469 127 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
establishment of protein localization to plasma membrane GO:0090002 34 0.012
mitotic nuclear division GO:0007067 48 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
negative regulation of growth GO:0045926 99 0.012
regulation of secretion by cell GO:1903530 249 0.012
heart process GO:0003015 94 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
action potential GO:0001508 78 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
external genitalia morphogenesis GO:0035261 1 0.012
negative regulation of kinase activity GO:0033673 81 0.012
Rat
hepaticobiliary system development GO:0061008 67 0.012
male sex differentiation GO:0046661 109 0.012
negative regulation of translation GO:0017148 22 0.012
smoothened signaling pathway GO:0007224 105 0.012
negative regulation of cell proliferation GO:0008285 296 0.011
oocyte differentiation GO:0009994 35 0.011
regulation of translational elongation GO:0006448 4 0.011
liver development GO:0001889 66 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
multicellular organism growth GO:0035264 161 0.011
synaptic vesicle transport GO:0048489 57 0.011
heart contraction GO:0060047 93 0.011
exocytosis GO:0006887 121 0.011
organ growth GO:0035265 117 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
positive regulation of proteolysis GO:0045862 85 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
placenta development GO:0001890 140 0.011
synaptic vesicle localization GO:0097479 59 0.011
regulation of hippo signaling GO:0035330 1 0.011
neutrophil mediated immunity GO:0002446 19 0.011
negative regulation of gene expression epigenetic GO:0045814 15 0.011

Wnk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
disease of anatomical entity DOID:7 0 0.020
Human
nervous system disease DOID:863 0 0.020
Human
inherited metabolic disorder DOID:655 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016