Mus musculus

176 known processes

Lhx2

LIM homeobox protein 2

(Aliases: Lim2,ap,apterous,Lh-2,LH2A)

Lhx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.496
forebrain development GO:0030900 302 0.351
neural tube development GO:0021915 160 0.328
central nervous system neuron differentiation GO:0021953 162 0.285
Mouse
axonogenesis GO:0007409 274 0.254
camera type eye development GO:0043010 266 0.241
telencephalon development GO:0021537 186 0.201
pallium development GO:0021543 120 0.194
regulation of neuron differentiation GO:0045664 281 0.190
Mouse
insulin metabolic process GO:1901142 3 0.173
embryonic epithelial tube formation GO:0001838 130 0.167
embryonic organ morphogenesis GO:0048562 276 0.163
Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.162
Zebrafish Mouse
amine metabolic process GO:0009308 45 0.160
positive regulation of rhodopsin gene expression GO:0045872 2 0.158
cellular amine metabolic process GO:0044106 44 0.153
axon guidance GO:0007411 141 0.144
sensory organ morphogenesis GO:0090596 242 0.137
Mouse
stem cell differentiation GO:0048863 268 0.133
Mouse
regulation of asymmetric cell division GO:0009786 4 0.132
cerebral cortex development GO:0021987 86 0.132
morphogenesis of embryonic epithelium GO:0016331 159 0.129
neuron projection guidance GO:0097485 141 0.126
primary neural tube formation GO:0014020 95 0.124
cell adhesion GO:0007155 329 0.123
angiogenesis GO:0001525 201 0.121
Mouse
negative regulation of molecular function GO:0044092 258 0.117
retina development in camera type eye GO:0060041 119 0.113
dendrite development GO:0016358 115 0.108
skeletal system development GO:0001501 356 0.107
Mouse
motor neuron migration GO:0097475 4 0.105
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.103
compound eye development GO:0048749 1 0.102
cerebral cortex radially oriented cell migration GO:0021799 31 0.102
Mouse
hindbrain development GO:0030902 128 0.101
Mouse
neural precursor cell proliferation GO:0061351 121 0.099
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.095
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.093
epithelial tube morphogenesis GO:0060562 303 0.092
positive regulation of cell development GO:0010720 237 0.091
neural tube closure GO:0001843 90 0.091
regulation of rhodopsin gene expression GO:0007468 3 0.090
negative regulation of phosphorus metabolic process GO:0010563 184 0.089
cellular amino acid metabolic process GO:0006520 103 0.088
neural tube formation GO:0001841 108 0.087
placenta development GO:0001890 140 0.087
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.086
stem cell development GO:0048864 219 0.084
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.083
appendage morphogenesis GO:0035107 149 0.083
Mouse
forebrain cell migration GO:0021885 58 0.083
Mouse
negative regulation of nervous system development GO:0051961 156 0.080
Mouse
tube closure GO:0060606 91 0.080
digestive system development GO:0055123 200 0.080
Mouse
cell fate commitment GO:0045165 210 0.077
Mouse
regulation of neuron projection development GO:0010975 169 0.077
regulation of protein kinase activity GO:0045859 232 0.077
regulation of response to wounding GO:1903034 189 0.076
Mouse
telencephalon cell migration GO:0022029 55 0.076
Mouse
blood vessel morphogenesis GO:0048514 285 0.075
Mouse
chemotaxis GO:0006935 247 0.075
central nervous system neuron development GO:0021954 67 0.074
Mouse
retina morphogenesis in camera type eye GO:0060042 45 0.073
Mouse
ectoderm formation GO:0001705 3 0.070
Mouse
brain segmentation GO:0035284 3 0.070
somitogenesis GO:0001756 69 0.069
Mouse
synaptic transmission GO:0007268 329 0.068
regulation of synaptic plasticity GO:0048167 87 0.066
regulation of transferase activity GO:0051338 263 0.065
cell proliferation in forebrain GO:0021846 30 0.065
Mouse
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.064
Mouse
peptidyl amino acid modification GO:0018193 336 0.062
Mouse
negative regulation of cell proliferation GO:0008285 296 0.061
negative regulation of protein metabolic process GO:0051248 282 0.061
limb morphogenesis GO:0035108 149 0.060
Mouse
negative regulation of phosphorylation GO:0042326 166 0.059
anterior commissure morphogenesis GO:0021960 6 0.059
cerebral cortex cell migration GO:0021795 44 0.059
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.058
synapse organization GO:0050808 125 0.057
bmp signaling pathway GO:0030509 93 0.057
renal system development GO:0072001 225 0.055
Mouse
cerebellum morphogenesis GO:0021587 42 0.055
Mouse
protein maturation GO:0051604 176 0.055
regulation of cell adhesion GO:0030155 154 0.055
regulation of cellular component biogenesis GO:0044087 181 0.055
positive regulation of secretion by cell GO:1903532 114 0.055
regulation of secretion GO:0051046 274 0.055
regulation of kinase activity GO:0043549 249 0.054
forebrain generation of neurons GO:0021872 63 0.054
Mouse
t cell activation GO:0042110 289 0.054
carbohydrate metabolic process GO:0005975 230 0.053
auditory receptor cell fate determination GO:0042668 3 0.053
photoreceptor cell development GO:0042461 40 0.052
regulation of cell migration GO:0030334 219 0.052
olfactory bulb development GO:0021772 30 0.052
regulation of organ morphogenesis GO:2000027 144 0.052
Mouse
cellular ketone metabolic process GO:0042180 84 0.051
central nervous system segmentation GO:0035283 3 0.051
neuroblast differentiation GO:0014016 2 0.051
neural tube patterning GO:0021532 43 0.051
regulation of hormone levels GO:0010817 211 0.050
morphogenesis of a branching structure GO:0001763 203 0.050
Mouse
spermatogenesis GO:0007283 284 0.050
positive regulation of nervous system development GO:0051962 221 0.050
Mouse
gonad morphogenesis GO:0035262 1 0.049
Mouse
heart morphogenesis GO:0003007 178 0.049
Mouse
regulation of cell projection organization GO:0031344 206 0.049
cell maturation GO:0048469 127 0.049
Mouse
photoreceptor cell differentiation GO:0046530 52 0.048
negative regulation of protein modification process GO:0031400 163 0.048
urogenital system development GO:0001655 261 0.048
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.047
Mouse
cerebral cortex radial glia guided migration GO:0021801 17 0.047
peripheral nervous system neuron axonogenesis GO:0048936 3 0.047
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
glial cell differentiation GO:0010001 131 0.046
protein processing GO:0016485 163 0.046
negative regulation of protein phosphorylation GO:0001933 126 0.045
hippocampus development GO:0021766 52 0.045
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.045
spinal cord development GO:0021510 81 0.045
Mouse
metencephalon development GO:0022037 89 0.045
Mouse
cerebral cortex neuron differentiation GO:0021895 19 0.044
Mouse
cytokine production GO:0001816 319 0.044
Mouse
epidermis development GO:0008544 187 0.044
lens development in camera type eye GO:0002088 62 0.043
forebrain regionalization GO:0021871 25 0.043
limbic system development GO:0021761 72 0.043
Mouse
lens morphogenesis in camera type eye GO:0002089 24 0.043
maintenance of apical basal cell polarity GO:0035090 3 0.043
regulation of secretion by cell GO:1903530 249 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.042
negative regulation of transferase activity GO:0051348 85 0.042
nephron tubule development GO:0072080 84 0.042
Mouse
eye photoreceptor cell development GO:0042462 31 0.041
palate development GO:0060021 76 0.041
hindbrain morphogenesis GO:0021575 46 0.041
Mouse
regulation of cell motility GO:2000145 236 0.041
hematopoietic progenitor cell differentiation GO:0002244 143 0.041
lymphocyte differentiation GO:0030098 242 0.041
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.040
head morphogenesis GO:0060323 34 0.040
epithelial tube formation GO:0072175 130 0.040
gland development GO:0048732 330 0.040
Mouse
motor neuron axon guidance GO:0008045 26 0.040
Mouse
segmentation GO:0035282 93 0.039
Mouse
gastrulation GO:0007369 116 0.039
Mouse
kidney development GO:0001822 213 0.039
Mouse
spinal cord motor neuron migration GO:0097476 4 0.039
Mouse
regulation of stem cell proliferation GO:0072091 78 0.039
negative regulation of cell development GO:0010721 169 0.039
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.038
aromatic compound catabolic process GO:0019439 286 0.038
neuron migration GO:0001764 122 0.038
Mouse
sensory perception GO:0007600 245 0.038
positive regulation of cell adhesion GO:0045785 80 0.038
molting cycle GO:0042303 90 0.038
regulation of cellular catabolic process GO:0031329 242 0.038
organic hydroxy compound metabolic process GO:1901615 203 0.037
diencephalon development GO:0021536 63 0.037
Zebrafish Mouse
skin development GO:0043588 220 0.037
midbrain hindbrain boundary development GO:0030917 9 0.037
regulation of neuron apoptotic process GO:0043523 122 0.037
Mouse
multicellular organism growth GO:0035264 161 0.037
central nervous system projection neuron axonogenesis GO:0021952 21 0.037
embryonic appendage morphogenesis GO:0035113 126 0.037
mesoderm development GO:0007498 100 0.036
monocarboxylic acid metabolic process GO:0032787 191 0.036
wound healing GO:0042060 157 0.036
mesenchymal cell differentiation GO:0048762 107 0.036
Mouse
response to growth factor GO:0070848 198 0.036
epithelial cell development GO:0002064 159 0.035
olfactory lobe development GO:0021988 32 0.035
small molecule biosynthetic process GO:0044283 132 0.035
immune effector process GO:0002252 321 0.035
protein ubiquitination GO:0016567 171 0.035
organic cyclic compound catabolic process GO:1901361 295 0.035
carbohydrate homeostasis GO:0033500 128 0.035
regulation of organelle organization GO:0033043 289 0.035
forebrain neuron fate commitment GO:0021877 13 0.035
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.035
fat cell differentiation GO:0045444 160 0.034
lateral motor column neuron migration GO:0097477 3 0.034
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.034
tube formation GO:0035148 140 0.034
glucose homeostasis GO:0042593 128 0.034
mapk cascade GO:0000165 281 0.034
regulation of binding GO:0051098 111 0.034
muscle cell differentiation GO:0042692 261 0.033
Mouse
regulation of peptidase activity GO:0052547 96 0.033
positive regulation of growth GO:0045927 104 0.033
developmental growth involved in morphogenesis GO:0060560 138 0.033
cell growth GO:0016049 130 0.033
epithelial cell morphogenesis GO:0003382 41 0.032
regulation of proteolysis GO:0030162 164 0.032
cerebellar cortex development GO:0021695 48 0.032
Mouse
ras protein signal transduction GO:0007265 77 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
mesoderm morphogenesis GO:0048332 64 0.032
multi multicellular organism process GO:0044706 109 0.032
anterior head development GO:0097065 2 0.032
Mouse
regulation of cytokine production GO:0001817 266 0.032
Mouse
sensory system development GO:0048880 3 0.032
Mouse
canonical wnt signaling pathway GO:0060070 130 0.031
Mouse
positive regulation of cell motility GO:2000147 116 0.031
negative regulation of intracellular signal transduction GO:1902532 167 0.031
extracellular structure organization GO:0043062 148 0.031
Mouse
amide transport GO:0042886 138 0.031
stem cell maintenance GO:0019827 130 0.031
regulation of inflammatory response GO:0050727 147 0.031
Mouse
chromatin modification GO:0016568 187 0.031
rhombomere morphogenesis GO:0021593 2 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
regulation of protein serine threonine kinase activity GO:0071900 157 0.031
macromolecule catabolic process GO:0009057 281 0.031
cell recognition GO:0008037 83 0.030
nephron development GO:0072006 109 0.030
Mouse
negative regulation of kinase activity GO:0033673 81 0.030
corpus callosum morphogenesis GO:0021540 3 0.030
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
regulation of cellular response to stress GO:0080135 159 0.030
hormone secretion GO:0046879 128 0.030
positive regulation of apoptotic process GO:0043065 217 0.029
rho protein signal transduction GO:0007266 32 0.029
epithelial cell migration GO:0010631 63 0.029
oxidation reduction process GO:0055114 342 0.029
protein localization to organelle GO:0033365 185 0.029
cardiac muscle tissue development GO:0048738 130 0.029
Mouse
organelle fission GO:0048285 170 0.029
stem cell proliferation GO:0072089 117 0.029
transdifferentiation GO:0060290 1 0.029
dentate gyrus development GO:0021542 14 0.029
Mouse
regulation of anterior head development GO:2000742 2 0.029
Mouse
cerebellum development GO:0021549 77 0.029
Mouse
neuron projection extension GO:1990138 64 0.028
ear morphogenesis GO:0042471 118 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
negative regulation of ovulation GO:0060280 1 0.028
cellular lipid metabolic process GO:0044255 323 0.028
cytoplasmic transport GO:0016482 234 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
female gonad development GO:0008585 71 0.027
Mouse
microtubule based process GO:0007017 236 0.027
chromatin organization GO:0006325 206 0.027
midgut development GO:0007494 4 0.027
germ cell development GO:0007281 185 0.027
neuroblast proliferation GO:0007405 49 0.027
regulation of vasculature development GO:1901342 88 0.027
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.026
ameboidal type cell migration GO:0001667 128 0.026
Mouse
cellular chemical homeostasis GO:0055082 215 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
nucleotide catabolic process GO:0009166 217 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
heterocycle catabolic process GO:0046700 280 0.026
tissue migration GO:0090130 68 0.026
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.026
neuron apoptotic process GO:0051402 142 0.025
Mouse
cell type specific apoptotic process GO:0097285 268 0.025
Mouse
negative regulation of proteolysis GO:0045861 74 0.025
negative regulation of protein processing GO:0010955 79 0.025
morphogenesis of a polarized epithelium GO:0001738 37 0.025
respiratory tube development GO:0030323 167 0.025
regulation of mapk cascade GO:0043408 248 0.025
response to acid chemical GO:0001101 111 0.025
response to organonitrogen compound GO:0010243 246 0.025
embryonic placenta development GO:0001892 98 0.025
cerebellar cortex formation GO:0021697 22 0.025
Mouse
striated muscle tissue development GO:0014706 293 0.025
Mouse
regulation of ovulation GO:0060278 3 0.025
regulation of cell cycle GO:0051726 281 0.025
cell fate determination GO:0001709 32 0.025
Mouse
ossification GO:0001503 216 0.025
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.024
positive regulation of secretion GO:0051047 130 0.024
regulation of protein localization GO:0032880 231 0.024
developmental maturation GO:0021700 193 0.024
Mouse
mitral valve morphogenesis GO:0003183 4 0.024
central nervous system neuron axonogenesis GO:0021955 28 0.024
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.024
extracellular matrix organization GO:0030198 147 0.024
Mouse
inflammatory response GO:0006954 244 0.024
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.024
skeletal muscle cell differentiation GO:0035914 66 0.024
regulation of protein processing GO:0070613 96 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.024
regulation of cell activation GO:0050865 289 0.024
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.024
epithelial to mesenchymal transition GO:0001837 47 0.024
neuron fate specification GO:0048665 30 0.024
Mouse
neuron death GO:0070997 154 0.024
Mouse
phenol containing compound metabolic process GO:0018958 60 0.024
branching morphogenesis of an epithelial tube GO:0048754 159 0.024
Mouse
epithelial cell proliferation GO:0050673 174 0.024
erythrocyte differentiation GO:0030218 88 0.024
positive regulation of cell cycle GO:0045787 92 0.024
development of primary female sexual characteristics GO:0046545 73 0.024
Mouse
negative regulation of cellular component organization GO:0051129 194 0.023
limb development GO:0060173 166 0.023
Mouse
positive regulation of anterior head development GO:2000744 2 0.023
Mouse
development of primary sexual characteristics GO:0045137 143 0.023
Mouse
negative regulation of protein maturation GO:1903318 79 0.023
endocardial cushion development GO:0003197 26 0.023
Mouse
layer formation in cerebral cortex GO:0021819 13 0.023
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.023
stem cell fate specification GO:0048866 3 0.023
transmission of nerve impulse GO:0019226 76 0.023
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.023
nucleoside metabolic process GO:0009116 246 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
gonad development GO:0008406 141 0.023
Mouse
regulation of angiogenesis GO:0045765 81 0.023
Mouse
nuclear division GO:0000280 158 0.023
glycoprotein metabolic process GO:0009100 116 0.023
purine nucleotide catabolic process GO:0006195 211 0.022
metanephric loop of henle development GO:0072236 4 0.022
forebrain neuron differentiation GO:0021879 52 0.022
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.022
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.022
peptidyl tyrosine modification GO:0018212 145 0.022
Mouse
cellular response to monosaccharide stimulus GO:0071326 47 0.022
positive regulation of protein modification process GO:0031401 299 0.022
Mouse
leukocyte differentiation GO:0002521 342 0.022
peripheral nervous system development GO:0007422 53 0.022
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.022
appendage development GO:0048736 166 0.022
Mouse
photoreceptor cell fate commitment GO:0046552 2 0.022
response to transforming growth factor beta GO:0071559 88 0.022
astrocyte fate commitment GO:0060018 4 0.022
transmembrane transport GO:0055085 412 0.022
organic hydroxy compound biosynthetic process GO:1901617 77 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
negative regulation of neuron projection regeneration GO:0070571 3 0.022
blastocyst development GO:0001824 80 0.022
corpus callosum development GO:0022038 10 0.022
positive regulation of kinase activity GO:0033674 155 0.022
myeloid cell differentiation GO:0030099 233 0.022
regulation of membrane potential GO:0042391 192 0.022
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.022
auditory receptor cell fate specification GO:0042667 1 0.021
cellular homeostasis GO:0019725 240 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
regulation of neuron death GO:1901214 134 0.021
Mouse
nucleotide metabolic process GO:0009117 332 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
cardiac muscle tissue morphogenesis GO:0055008 44 0.021
Mouse
fasciculation of sensory neuron axon GO:0097155 3 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
protein catabolic process GO:0030163 221 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
Mouse
negative regulation of neuron projection development GO:0010977 50 0.021
maintenance of location GO:0051235 89 0.021
regulation of auditory receptor cell differentiation GO:0045607 4 0.021
exocytosis GO:0006887 121 0.021
regulation of cell growth GO:0001558 91 0.021
Mouse
negative regulation of immune system process GO:0002683 209 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
response to monosaccharide GO:0034284 67 0.021
covalent chromatin modification GO:0016569 163 0.021
cell division GO:0051301 120 0.021
regulation of protein maturation GO:1903317 96 0.021
visceral motor neuron differentiation GO:0021524 3 0.020
Mouse
nitrogen compound transport GO:0071705 271 0.020
cell differentiation in spinal cord GO:0021515 53 0.020
Mouse
purine containing compound catabolic process GO:0072523 213 0.020
regulation of transmembrane transport GO:0034762 128 0.020
neural crest cell development GO:0014032 48 0.020
Mouse
apoptotic signaling pathway GO:0097190 306 0.020
rostrocaudal neural tube patterning GO:0021903 12 0.020
regulation of mast cell differentiation GO:0060375 3 0.020
digestive tract development GO:0048565 190 0.020
Mouse
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.020
negative regulation of response to wounding GO:1903035 77 0.020
Mouse
skeletal system morphogenesis GO:0048705 203 0.020
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.020
alcohol metabolic process GO:0006066 116 0.020
regulation of protein transport GO:0051223 163 0.020
megakaryocyte differentiation GO:0030219 26 0.020
negative chemotaxis GO:0050919 14 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.020
tendon cell differentiation GO:0035990 4 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.019
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.019
positive regulation of transferase activity GO:0051347 167 0.019
mitral valve development GO:0003174 4 0.019
ureteric bud morphogenesis GO:0060675 62 0.019
Mouse
positive regulation of bmp signaling pathway GO:0030513 23 0.019
somite development GO:0061053 81 0.019
Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.019
respiratory system development GO:0060541 190 0.019
regulation of defense response GO:0031347 233 0.019
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
midbrain development GO:0030901 35 0.019
Mouse
regulation of carbohydrate metabolic process GO:0006109 75 0.019
spinal cord motor neuron differentiation GO:0021522 35 0.019
Mouse
epithalamus development GO:0021538 2 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
hormone metabolic process GO:0042445 86 0.019
hemangioblast cell differentiation GO:0060217 1 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.019
ectodermal cell differentiation GO:0010668 3 0.019
cerebellar purkinje cell layer development GO:0021680 26 0.019
Mouse
positive regulation of programmed cell death GO:0043068 218 0.019
renal vesicle induction GO:0072034 3 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
inner ear receptor cell differentiation GO:0060113 61 0.019
regulation of cell cycle process GO:0010564 160 0.019
male gamete generation GO:0048232 285 0.018
forebrain radial glial cell differentiation GO:0021861 4 0.018
gtp catabolic process GO:0006184 143 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
peptidyl tyrosine phosphorylation GO:0018108 143 0.018
Mouse
lateral inhibition GO:0046331 1 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
myotube differentiation GO:0014902 105 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
somatic stem cell maintenance GO:0035019 47 0.018
retinal bipolar neuron differentiation GO:0060040 5 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
positive regulation of organelle organization GO:0010638 128 0.018
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.018
dna metabolic process GO:0006259 303 0.018
membrane organization GO:0061024 245 0.018
forebrain neuron development GO:0021884 30 0.018
Mouse
digestive tract morphogenesis GO:0048546 147 0.018
Mouse
negative regulation of synapse assembly GO:0051964 3 0.018
mesenchymal cell development GO:0014031 93 0.018
Mouse
closure of optic fissure GO:0061386 2 0.018
androgen biosynthetic process GO:0006702 4 0.018
cardiocyte differentiation GO:0035051 87 0.018
Mouse
cellular protein catabolic process GO:0044257 155 0.018
histone modification GO:0016570 159 0.018
cell differentiation involved in kidney development GO:0061005 33 0.018
Mouse
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
metanephros development GO:0001656 79 0.018
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.018
metanephric dct cell differentiation GO:0072240 3 0.017
regulation of hydrolase activity GO:0051336 246 0.017
embryonic eye morphogenesis GO:0048048 29 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
organophosphate catabolic process GO:0046434 232 0.017
gliogenesis GO:0042063 141 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
rap protein signal transduction GO:0032486 3 0.017
regulation of exocytosis GO:0017157 61 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.017
regulation of homeostatic process GO:0032844 182 0.017
cell fate specification GO:0001708 72 0.017
Mouse
cardiac ventricle development GO:0003231 83 0.017
Mouse
locomotory behavior GO:0007626 195 0.017
skeletal muscle organ development GO:0060538 163 0.017
trophectodermal cell differentiation GO:0001829 21 0.017
negative regulation of inflammatory response GO:0050728 61 0.017
Mouse
nephron tubule morphogenesis GO:0072078 68 0.017
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.017
regulation of neural retina development GO:0061074 3 0.017
homeostasis of number of cells GO:0048872 210 0.017
protein localization to nucleus GO:0034504 121 0.017
muscle cell development GO:0055001 133 0.017
astrocyte differentiation GO:0048708 43 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
regulation of system process GO:0044057 200 0.017
hair cell differentiation GO:0035315 40 0.017
mitochondrion distribution GO:0048311 4 0.017
myelination GO:0042552 74 0.017
mitochondrion organization GO:0007005 134 0.017
multicellular organismal signaling GO:0035637 91 0.017
paraxial mesodermal cell fate commitment GO:0048343 2 0.017
b cell differentiation GO:0030183 78 0.017
adult behavior GO:0030534 135 0.017
negative regulation of neuron death GO:1901215 98 0.017
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
paraxial mesodermal cell differentiation GO:0048342 2 0.016
lipid biosynthetic process GO:0008610 179 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
Mouse
ribonucleoside metabolic process GO:0009119 245 0.016
embryonic limb morphogenesis GO:0030326 126 0.016
synapse assembly GO:0007416 56 0.016
regulation of neural precursor cell proliferation GO:2000177 70 0.016
Mouse

Lhx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.060
disease of anatomical entity DOID:7 0 0.060
eye and adnexa disease DOID:1492 0 0.060
nervous system disease DOID:863 0 0.060
eye disease DOID:5614 0 0.038