Mus musculus

74 known processes

Lhx4

LIM homeobox protein 4

(Aliases: Gsh-4,Gsh4)

Lhx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
motor neuron migration GO:0097475 4 0.709
Mouse
ectoderm formation GO:0001705 3 0.690
Mouse
macrophage colony stimulating factor production GO:0036301 1 0.684
Mouse
central nervous system neuron differentiation GO:0021953 162 0.677
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.665
Mouse
granulocyte colony stimulating factor production GO:0071611 1 0.656
Mouse
regionalization GO:0003002 337 0.647
Mouse
visceral motor neuron differentiation GO:0021524 3 0.589
Mouse
camera type eye development GO:0043010 266 0.584
Mouse
gland development GO:0048732 330 0.555
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.547
Mouse
embryonic skeletal system development GO:0048706 120 0.541
Mouse
positive regulation of macrophage colony stimulating factor production GO:1901258 1 0.513
Mouse
medial motor column neuron differentiation GO:0021526 2 0.505
forebrain development GO:0030900 302 0.475
Mouse
muscle tissue development GO:0060537 308 0.472
Mouse
stem cell development GO:0048864 219 0.461
Mouse
cell fate commitment GO:0045165 210 0.455
Mouse
neuron fate specification GO:0048665 30 0.455
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.442
uterine epithelium development GO:0035847 1 0.428
Mouse
telencephalon cell migration GO:0022029 55 0.426
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.421
regulation of cellular ketone metabolic process GO:0010565 66 0.418
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.400
Mouse
cell fate commitment involved in pattern specification GO:0060581 14 0.399
Mouse
endocrine system development GO:0035270 98 0.399
Mouse
stem cell differentiation GO:0048863 268 0.398
Mouse
cerebral cortex development GO:0021987 86 0.396
Mouse
striated muscle tissue development GO:0014706 293 0.394
Mouse
spinal cord development GO:0021510 81 0.393
limb development GO:0060173 166 0.383
Mouse
regulation of anterior head development GO:2000742 2 0.382
Mouse
epidermis development GO:0008544 187 0.362
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.358
Mouse
axonogenesis GO:0007409 274 0.346
cerebellar cortex formation GO:0021697 22 0.339
Mouse
sensory perception GO:0007600 245 0.336
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.330
Mouse
hindbrain morphogenesis GO:0021575 46 0.327
Mouse
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.320
Mouse
cerebellar purkinje cell differentiation GO:0021702 13 0.283
Mouse
cell differentiation in hindbrain GO:0021533 24 0.274
Mouse
telencephalon development GO:0021537 186 0.271
Mouse
synaptic transmission GO:0007268 329 0.265
neuron projection guidance GO:0097485 141 0.259
regulation of membrane potential GO:0042391 192 0.259
hindbrain development GO:0030902 128 0.256
Mouse
cellular ketone metabolic process GO:0042180 84 0.248
cardiac chamber development GO:0003205 108 0.248
Mouse
diencephalon development GO:0021536 63 0.240
Mouse
mesoderm development GO:0007498 100 0.240
Mouse
skeletal system development GO:0001501 356 0.236
Mouse
appendage morphogenesis GO:0035107 149 0.236
Mouse
mesenchymal cell differentiation GO:0048762 107 0.235
Mouse
regulation of macrophage colony stimulating factor production GO:1901256 1 0.233
Mouse
cell differentiation involved in kidney development GO:0061005 33 0.224
Mouse
negative regulation of nervous system development GO:0051961 156 0.211
Mouse
spinal cord motor neuron migration GO:0097476 4 0.210
Mouse
cell proliferation in forebrain GO:0021846 30 0.209
Mouse
cellular amine metabolic process GO:0044106 44 0.203
learning or memory GO:0007611 148 0.202
Mouse
neuronal action potential GO:0019228 54 0.201
multicellular organismal signaling GO:0035637 91 0.199
cardiac ventricle development GO:0003231 83 0.197
Mouse
placenta development GO:0001890 140 0.196
renal tubule development GO:0061326 87 0.193
Mouse
forebrain neuron differentiation GO:0021879 52 0.182
Mouse
forebrain generation of neurons GO:0021872 63 0.180
Mouse
maintenance of apical basal cell polarity GO:0035090 3 0.179
Mouse
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.177
Mouse
ventral spinal cord interneuron differentiation GO:0021514 16 0.177
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.176
Mouse
regulation of embryonic development GO:0045995 71 0.176
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 14 0.175
Mouse
regulation of response to wounding GO:1903034 189 0.175
Mouse
heart morphogenesis GO:0003007 178 0.172
Mouse
positive regulation of protein kinase b signaling GO:0051897 32 0.167
negative regulation of cell development GO:0010721 169 0.164
Mouse
cellular amino acid metabolic process GO:0006520 103 0.163
somite development GO:0061053 81 0.161
Mouse
appendage development GO:0048736 166 0.158
Mouse
sensory organ morphogenesis GO:0090596 242 0.158
Mouse
cardiac cell fate determination GO:0060913 2 0.157
Mouse
cerebellar cortex development GO:0021695 48 0.157
Mouse
forebrain neuron fate commitment GO:0021877 13 0.156
Mouse
positive regulation of growth GO:0045927 104 0.156
spinal cord dorsal ventral patterning GO:0021513 23 0.154
Mouse
nephron development GO:0072006 109 0.153
Mouse
embryonic organ morphogenesis GO:0048562 276 0.153
Mouse
germ cell development GO:0007281 185 0.152
epithelial tube morphogenesis GO:0060562 303 0.150
Mouse
cardiac septum development GO:0003279 59 0.149
Mouse
circulatory system process GO:0003013 197 0.149
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.148
Mouse
cardiac muscle tissue development GO:0048738 130 0.145
Mouse
ensheathment of neurons GO:0007272 76 0.145
cardiac ventricle morphogenesis GO:0003208 50 0.144
Mouse
tube formation GO:0035148 140 0.144
Mouse
neural tube development GO:0021915 160 0.144
Mouse
negative regulation of response to wounding GO:1903035 77 0.143
Mouse
ear development GO:0043583 200 0.140
regulation of organ morphogenesis GO:2000027 144 0.139
Mouse
adult behavior GO:0030534 135 0.132
skin development GO:0043588 220 0.132
Mouse
pancreatic a cell fate commitment GO:0003326 2 0.131
detection of light stimulus GO:0009583 25 0.130
nephric duct elongation GO:0035849 1 0.129
Mouse
fat cell differentiation GO:0045444 160 0.129
stem cell maintenance GO:0019827 130 0.126
ureteric bud development GO:0001657 94 0.125
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.124
Mouse
negative regulation of cell proliferation GO:0008285 296 0.124
eye photoreceptor cell differentiation GO:0001754 41 0.123
regulation of cellular amine metabolic process GO:0033238 20 0.121
urogenital system development GO:0001655 261 0.121
Mouse
embryonic placenta development GO:0001892 98 0.121
carbohydrate homeostasis GO:0033500 128 0.121
segmentation GO:0035282 93 0.120
Mouse
dorsal spinal cord development GO:0021516 20 0.118
Mouse
forebrain neuron development GO:0021884 30 0.116
Mouse
ear morphogenesis GO:0042471 118 0.115
axon ensheathment GO:0008366 76 0.115
retina morphogenesis in camera type eye GO:0060042 45 0.111
Mouse
spinal cord patterning GO:0021511 25 0.111
Mouse
endocrine process GO:0050886 39 0.110
regulation of defense response GO:0031347 233 0.110
Mouse
pituitary gland development GO:0021983 38 0.110
Mouse
respiratory system development GO:0060541 190 0.110
negative regulation of neuron death GO:1901215 98 0.108
Mouse
kidney epithelium development GO:0072073 121 0.108
Mouse
cation transport GO:0006812 399 0.107
myelination GO:0042552 74 0.106
pancreas development GO:0031016 57 0.106
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.106
muscle cell differentiation GO:0042692 261 0.106
Mouse
mesenchymal cell development GO:0014031 93 0.105
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.104
inflammatory response GO:0006954 244 0.102
Mouse
regulation of ion transport GO:0043269 215 0.102
mesenchyme development GO:0060485 152 0.101
Mouse
positive regulation of anterior head development GO:2000744 2 0.098
Mouse
wound healing GO:0042060 157 0.098
action potential GO:0001508 78 0.096
cerebellar cortex morphogenesis GO:0021696 32 0.096
Mouse
ventricular cardiac muscle tissue development GO:0003229 38 0.096
Mouse
neural precursor cell proliferation GO:0061351 121 0.095
Mouse
regulation of muscle tissue development GO:1901861 97 0.094
limbic system development GO:0021761 72 0.094
Mouse
metanephric s shaped body morphogenesis GO:0072284 2 0.092
Mouse
developmental maturation GO:0021700 193 0.091
Mouse
bmp signaling pathway GO:0030509 93 0.090
regulation of system process GO:0044057 200 0.089
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.088
organophosphate biosynthetic process GO:0090407 122 0.088
transmission of nerve impulse GO:0019226 76 0.087
nephron epithelium development GO:0072009 92 0.087
Mouse
connective tissue development GO:0061448 179 0.086
epithelial tube formation GO:0072175 130 0.086
Mouse
development of primary male sexual characteristics GO:0046546 88 0.085
Mouse
locomotory behavior GO:0007626 195 0.084
morphogenesis of embryonic epithelium GO:0016331 159 0.082
Mouse
regulation of cell cycle GO:0051726 281 0.082
Fly
cerebral cortex neuron differentiation GO:0021895 19 0.080
Mouse
mesoderm formation GO:0001707 62 0.080
cardiac muscle tissue morphogenesis GO:0055008 44 0.079
Mouse
hypophysis morphogenesis GO:0048850 3 0.078
cell fate specification GO:0001708 72 0.077
Mouse
cell maturation GO:0048469 127 0.077
Mouse
metanephric loop of henle development GO:0072236 4 0.076
positive regulation of cell cycle GO:0045787 92 0.076
muscle tissue morphogenesis GO:0060415 53 0.075
Mouse
lymphocyte differentiation GO:0030098 242 0.074
auditory receptor cell fate specification GO:0042667 1 0.074
gabaergic neuron differentiation GO:0097154 11 0.074
Mouse
oxidation reduction process GO:0055114 342 0.073
regulation of homeostatic process GO:0032844 182 0.073
cation homeostasis GO:0055080 212 0.072
renal system development GO:0072001 225 0.071
Mouse
detection of stimulus GO:0051606 84 0.071
Worm
embryonic heart tube development GO:0035050 65 0.071
regulation of hormone levels GO:0010817 211 0.071
metencephalon development GO:0022037 89 0.071
Mouse
male gamete generation GO:0048232 285 0.071
cation transmembrane transport GO:0098655 266 0.070
metal ion homeostasis GO:0055065 189 0.070
neuron death GO:0070997 154 0.070
Mouse
cerebellum development GO:0021549 77 0.069
Mouse
digestive tract development GO:0048565 190 0.069
Mouse
hexose metabolic process GO:0019318 98 0.069
hypothalamus development GO:0021854 16 0.069
cervix development GO:0060067 2 0.069
Mouse
mesonephros development GO:0001823 97 0.068
Mouse
response to radiation GO:0009314 165 0.068
sensory perception of light stimulus GO:0050953 54 0.068
metanephros morphogenesis GO:0003338 24 0.068
Mouse
skeletal muscle organ development GO:0060538 163 0.068
cerebral cortex cell migration GO:0021795 44 0.067
Mouse
embryonic epithelial tube formation GO:0001838 130 0.067
Mouse
amine metabolic process GO:0009308 45 0.066
male sex differentiation GO:0046661 109 0.066
Mouse
regulation of granulocyte colony stimulating factor production GO:0071655 1 0.066
Mouse
regulation of organ formation GO:0003156 34 0.066
Mouse
skeletal muscle cell differentiation GO:0035914 66 0.066
cerebellum morphogenesis GO:0021587 42 0.065
Mouse
pallium development GO:0021543 120 0.065
Mouse
auditory receptor cell fate determination GO:0042668 3 0.065
somitogenesis GO:0001756 69 0.065
Mouse
regulation of neural retina development GO:0061074 3 0.064
outflow tract morphogenesis GO:0003151 53 0.064
Mouse
peptidyl amino acid modification GO:0018193 336 0.064
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.064
Mouse
macromolecule catabolic process GO:0009057 281 0.063
metanephric nephron morphogenesis GO:0072273 19 0.062
Mouse
sensory perception of sound GO:0007605 97 0.062
response to inactivity GO:0014854 4 0.062
nucleoside phosphate metabolic process GO:0006753 338 0.062
inner ear receptor cell differentiation GO:0060113 61 0.062
gastrulation GO:0007369 116 0.062
Mouse
forebrain regionalization GO:0021871 25 0.061
Mouse
endoderm development GO:0007492 45 0.061
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.061
ion transmembrane transport GO:0034220 361 0.061
gonad morphogenesis GO:0035262 1 0.061
Mouse
neuron migration GO:0001764 122 0.061
Mouse
developmental cell growth GO:0048588 84 0.061
Mouse
neuron projection extension GO:1990138 64 0.061
Mouse
regulation of secretion by cell GO:1903530 249 0.061
epithelial cell development GO:0002064 159 0.060
multicellular organism growth GO:0035264 161 0.059
nitrogen compound transport GO:0071705 271 0.059
digestive tract morphogenesis GO:0048546 147 0.059
Mouse
mesenchyme morphogenesis GO:0072132 32 0.059
Mouse
pancreatic pp cell differentiation GO:0003312 2 0.059
nerve development GO:0021675 67 0.059
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.059
chromatin modification GO:0016568 187 0.058
positive regulation of protein modification process GO:0031401 299 0.058
Mouse
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.057
Mouse
tumor necrosis factor production GO:0032640 50 0.057
Mouse
negative regulation of dna binding GO:0043392 20 0.057
Mouse
neural retina development GO:0003407 41 0.056
Mouse
carbohydrate metabolic process GO:0005975 230 0.056
paraxial mesodermal cell differentiation GO:0048342 2 0.055
glucose homeostasis GO:0042593 128 0.055
regulation of fat cell differentiation GO:0045598 81 0.055
peptide hormone secretion GO:0030072 109 0.055
monosaccharide metabolic process GO:0005996 106 0.055
regulation of neuron differentiation GO:0045664 281 0.054
Mouse
aorta development GO:0035904 23 0.054
trabecular meshwork development GO:0002930 2 0.054
Mouse
loop of henle development GO:0072070 10 0.053
telencephalon regionalization GO:0021978 14 0.053
Mouse
hormone secretion GO:0046879 128 0.053
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.053
insulin secretion GO:0030073 89 0.053
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.052
auditory receptor cell differentiation GO:0042491 37 0.052
nephron tubule epithelial cell differentiation GO:0072160 11 0.052
Mouse
dendrite development GO:0016358 115 0.052
central nervous system neuron development GO:0021954 67 0.051
Mouse
retina development in camera type eye GO:0060041 119 0.051
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.051
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.051
cellular chemical homeostasis GO:0055082 215 0.051
hematopoietic progenitor cell differentiation GO:0002244 143 0.051
axon guidance GO:0007411 141 0.051
forebrain morphogenesis GO:0048853 17 0.051
regulation of stem cell proliferation GO:0072091 78 0.050
embryonic limb morphogenesis GO:0030326 126 0.049
establishment or maintenance of cell polarity GO:0007163 86 0.049
Mouse
hair follicle development GO:0001942 85 0.049
Mouse
peptide secretion GO:0002790 114 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.049
morphogenesis of a branching epithelium GO:0061138 193 0.049
Mouse
metanephros development GO:0001656 79 0.049
Mouse
renal vesicle morphogenesis GO:0072077 15 0.049
Mouse
limb morphogenesis GO:0035108 149 0.048
Mouse
neural tube formation GO:0001841 108 0.048
Mouse
response to light stimulus GO:0009416 135 0.048
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.048
negative regulation of phosphate metabolic process GO:0045936 184 0.048
determination of left right symmetry GO:0007368 80 0.047
comma shaped body morphogenesis GO:0072049 5 0.047
Mouse
primary neural tube formation GO:0014020 95 0.047
Mouse
hair cell differentiation GO:0035315 40 0.047
peripheral nervous system development GO:0007422 53 0.046
Mouse
neural tube closure GO:0001843 90 0.046
Mouse
ameboidal type cell migration GO:0001667 128 0.046
Mouse
deltoid tuberosity development GO:0035993 3 0.046
embryonic eye morphogenesis GO:0048048 29 0.046
aromatic compound catabolic process GO:0019439 286 0.045
regulation of auditory receptor cell differentiation GO:0045607 4 0.045
regulation of asymmetric cell division GO:0009786 4 0.045
pancreatic pp cell fate commitment GO:0003329 2 0.045
cerebral cortex radially oriented cell migration GO:0021799 31 0.045
Mouse
lung development GO:0030324 164 0.045
gliogenesis GO:0042063 141 0.045
positive regulation of cytokine production GO:0001819 174 0.045
Mouse
regulation of lipid metabolic process GO:0019216 118 0.045
negative regulation of neuron apoptotic process GO:0043524 92 0.044
Mouse
hypothalamus cell differentiation GO:0021979 8 0.044
anterior head development GO:0097065 2 0.044
Mouse
positive regulation of cell activation GO:0050867 158 0.044
olfactory bulb development GO:0021772 30 0.044
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.044
epithelial cell proliferation GO:0050673 174 0.044
cardiac septum morphogenesis GO:0060411 46 0.044
Mouse
regulation of cartilage development GO:0061035 44 0.043
positive regulation of cellular component biogenesis GO:0044089 94 0.043
cell type specific apoptotic process GO:0097285 268 0.043
Mouse
muscle cell development GO:0055001 133 0.043
brain morphogenesis GO:0048854 32 0.043
regulation of interleukin 1 alpha production GO:0032650 4 0.042
Mouse
detection of abiotic stimulus GO:0009582 60 0.042
Worm
regulation of cell activation GO:0050865 289 0.042
negative regulation of defense response GO:0031348 77 0.042
Mouse
positive regulation of nervous system development GO:0051962 221 0.042
Mouse
renal tubule morphogenesis GO:0061333 72 0.041
Mouse
regulation of cellular catabolic process GO:0031329 242 0.041
pharynx development GO:0060465 1 0.041
adult locomotory behavior GO:0008344 91 0.041
paramesonephric duct development GO:0061205 3 0.041
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.041
mechanoreceptor differentiation GO:0042490 67 0.041
regulation of glucose metabolic process GO:0010906 60 0.041
spermatogenesis GO:0007283 284 0.041
regulation of neuron apoptotic process GO:0043523 122 0.040
Mouse
head morphogenesis GO:0060323 34 0.040
odontogenesis of dentin containing tooth GO:0042475 66 0.040
Mouse
intracellular distribution of mitochondria GO:0048312 1 0.040
regulation of secondary heart field cardioblast proliferation GO:0003266 9 0.040
Mouse
globus pallidus development GO:0021759 2 0.040
chromatin organization GO:0006325 206 0.040
regulation of stem cell differentiation GO:2000736 50 0.040
positive regulation of cell development GO:0010720 237 0.040
g protein coupled receptor signaling pathway GO:0007186 243 0.040
positive regulation of interleukin 1 alpha production GO:0032730 4 0.040
Mouse
neural crest cell development GO:0014032 48 0.039
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.039
modification dependent protein catabolic process GO:0019941 133 0.039
tube closure GO:0060606 91 0.039
Mouse
positive regulation of interleukin 12 production GO:0032735 21 0.039
Mouse
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.038
Mouse
regulation of glial cell differentiation GO:0045685 41 0.038
positive regulation of lymphocyte activation GO:0051251 140 0.038
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.038
Mouse
regulation of organ growth GO:0046620 61 0.038
mesonephric epithelium development GO:0072163 94 0.038
Mouse
trophectodermal cell differentiation GO:0001829 21 0.038
cochlea morphogenesis GO:0090103 22 0.038
cartilage development GO:0051216 140 0.038
cochlea development GO:0090102 35 0.038
organ growth GO:0035265 117 0.038
Mouse
cerebellar purkinje cell layer development GO:0021680 26 0.038
Mouse
cardiac atrium morphogenesis GO:0003209 23 0.037
Mouse
regulation of neuron death GO:1901214 134 0.037
Mouse
kidney development GO:0001822 213 0.037
Mouse
purine nucleotide metabolic process GO:0006163 302 0.037
ventral spinal cord development GO:0021517 48 0.037
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation GO:0021937 6 0.037
Mouse
t cell differentiation GO:0030217 174 0.036
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.036
cellular response to lipid GO:0071396 145 0.036
lateral inhibition GO:0046331 1 0.036
thick ascending limb development GO:0072023 2 0.036
amide transport GO:0042886 138 0.035
epidermis morphogenesis GO:0048730 33 0.035
somatotropin secreting cell development GO:0060133 2 0.035
metanephric ascending thin limb development GO:0072218 2 0.035
neuromuscular process controlling balance GO:0050885 59 0.035
adenohypophysis development GO:0021984 14 0.035
regulation of inflammatory response GO:0050727 147 0.035
Mouse
cell differentiation involved in embryonic placenta development GO:0060706 26 0.035
modification dependent macromolecule catabolic process GO:0043632 133 0.035
inner ear morphogenesis GO:0042472 101 0.034
glial cell differentiation GO:0010001 131 0.034
neurotransmitter transport GO:0006836 76 0.034
regulation of kinase activity GO:0043549 249 0.034
thermosensory behavior GO:0040040 1 0.034
Worm
bundle of his development GO:0003166 4 0.034
regulation of bmp signaling pathway GO:0030510 60 0.034
regulation of transmembrane transport GO:0034762 128 0.034
regulation of organelle organization GO:0033043 289 0.033
neurohypophysis development GO:0021985 2 0.033
sensory perception of chemical stimulus GO:0007606 51 0.033
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.033
cardiac atrium development GO:0003230 24 0.033
Mouse
positive regulation of organelle organization GO:0010638 128 0.033
retina layer formation GO:0010842 16 0.033
Mouse
endoderm formation GO:0001706 20 0.032
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.032
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.032
retinal ganglion cell axon guidance GO:0031290 18 0.032
Mouse
regulation of circadian sleep wake cycle GO:0042749 3 0.032
response to extracellular stimulus GO:0009991 127 0.032
extraocular skeletal muscle development GO:0002074 2 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
neuron apoptotic process GO:0051402 142 0.032
Mouse
response to organonitrogen compound GO:0010243 246 0.032
regulation of interleukin 6 production GO:0032675 55 0.032
Mouse
female gonad development GO:0008585 71 0.032
Mouse
regulation of cytokine production GO:0001817 266 0.032
Mouse
lateral motor column neuron migration GO:0097477 3 0.031
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.031
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.031
blood circulation GO:0008015 195 0.031
olfactory lobe development GO:0021988 32 0.031
Mouse
forebrain cell migration GO:0021885 58 0.031
Mouse
peptidyl tyrosine modification GO:0018212 145 0.031
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
regulation of circadian rhythm GO:0042752 58 0.031
neutral lipid metabolic process GO:0006638 57 0.030
determination of heart left right asymmetry GO:0061371 48 0.030
heart process GO:0003015 94 0.030
interferon gamma production GO:0032609 67 0.030
Mouse
epithalamus development GO:0021538 2 0.030
regulation of retina development in camera type eye GO:1902866 3 0.030
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.030
Mouse
cell proliferation involved in heart morphogenesis GO:0061323 15 0.030
Mouse
camera type eye photoreceptor cell differentiation GO:0060219 15 0.030
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.030
cell differentiation in spinal cord GO:0021515 53 0.030
peptidyl lysine modification GO:0018205 77 0.030
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.029
metanephric thick ascending limb development GO:0072233 2 0.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.029
detection of external stimulus GO:0009581 61 0.029
Worm
photoreceptor cell differentiation GO:0046530 52 0.029
cardiac muscle cell differentiation GO:0055007 69 0.029
formation of primary germ layer GO:0001704 77 0.028
Mouse
muscle system process GO:0003012 141 0.028
striated muscle cell development GO:0055002 125 0.028
embryonic heart tube morphogenesis GO:0003143 51 0.028
positive regulation of kidney development GO:0090184 28 0.028
Mouse
mesoderm morphogenesis GO:0048332 64 0.028
respiratory tube development GO:0030323 167 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
digestive system development GO:0055123 200 0.028
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.028
detection of visible light GO:0009584 14 0.028
regulation of t cell activation GO:0050863 170 0.028
organic anion transport GO:0015711 137 0.028
dorsal ventral axon guidance GO:0033563 3 0.028
spinal cord motor neuron differentiation GO:0021522 35 0.028
outflow tract septum morphogenesis GO:0003148 11 0.027
Mouse
heart growth GO:0060419 45 0.027
inner cell mass cell fate commitment GO:0001827 2 0.027
cellular homeostasis GO:0019725 240 0.027
hair follicle morphogenesis GO:0031069 29 0.027
dentate gyrus development GO:0021542 14 0.027
Mouse
synapse organization GO:0050808 125 0.027
negative regulation of fat cell differentiation GO:0045599 36 0.027
parasympathetic nervous system development GO:0048486 19 0.027
brain segmentation GO:0035284 3 0.026
positive regulation of epithelial cell proliferation GO:0050679 68 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
regulation of gliogenesis GO:0014013 50 0.026
left lung morphogenesis GO:0060460 3 0.026
regulation of cardiac muscle tissue growth GO:0055021 26 0.026
adaptive immune response GO:0002250 155 0.026
sensory system development GO:0048880 3 0.026
Mouse
keratinocyte differentiation GO:0030216 48 0.026
interleukin 6 production GO:0032635 58 0.026
Mouse
oviduct development GO:0060066 3 0.026
Mouse
peripheral nervous system neuron axonogenesis GO:0048936 3 0.026
Mouse
astrocyte differentiation GO:0048708 43 0.026
visual perception GO:0007601 52 0.026
polarity specification of proximal distal axis GO:0010085 2 0.026
immunoglobulin production GO:0002377 73 0.026
regulation of protein kinase activity GO:0045859 232 0.026
lens development in camera type eye GO:0002088 62 0.026
protein catabolic process GO:0030163 221 0.025
myeloid cell differentiation GO:0030099 233 0.025
nuclear division GO:0000280 158 0.025
ectodermal cell differentiation GO:0010668 3 0.025
ventricular compact myocardium morphogenesis GO:0003223 2 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
morphogenesis of a branching structure GO:0001763 203 0.025
Mouse
skin morphogenesis GO:0043589 38 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.025
regulation of epithelial cell proliferation GO:0050678 141 0.025
negative regulation of inflammatory response GO:0050728 61 0.025
Mouse
cell proliferation in external granule layer GO:0021924 10 0.024
female sex differentiation GO:0046660 84 0.024
Mouse
cell growth GO:0016049 130 0.024
Mouse
viral gene expression GO:0019080 3 0.024
cellular response to organic cyclic compound GO:0071407 87 0.024
alcohol metabolic process GO:0006066 116 0.024
regulation of epidermal cell differentiation GO:0045604 21 0.024
negative regulation of epithelial cell proliferation GO:0050680 64 0.024

Lhx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.106
disease of anatomical entity DOID:7 0 0.106
nervous system disease DOID:863 0 0.106
eye and adnexa disease DOID:1492 0 0.037
eye disease DOID:5614 0 0.037