Mus musculus

86 known processes

Lrpprc

leucine-rich PPR-motif containing

(Aliases: Gp130,Lrp130,C76645,3110001K13Rik,Lsfc)

Lrpprc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to endoplasmic reticulum stress GO:0034976 53 0.616
protein targeting to mitochondrion GO:0006626 6 0.427
mitochondrion organization GO:0007005 134 0.384
heterocycle catabolic process GO:0046700 280 0.313
protein refolding GO:0042026 1 0.281
generation of precursor metabolites and energy GO:0006091 103 0.277
innate immune response GO:0045087 157 0.276
mitochondrial membrane organization GO:0007006 26 0.243
mitochondrial translation GO:0032543 4 0.240
energy derivation by oxidation of organic compounds GO:0015980 77 0.188
mitochondrial transport GO:0006839 36 0.181
response to oxidative stress GO:0006979 123 0.179
coenzyme metabolic process GO:0006732 52 0.175
defecation GO:0030421 1 0.151
trna aminoacylation GO:0043039 1 0.151
neuron apoptotic process GO:0051402 142 0.134
cellular response to oxidative stress GO:0034599 76 0.130
purine ribonucleotide metabolic process GO:0009150 290 0.130
nucleobase containing small molecule metabolic process GO:0055086 352 0.119
response to reactive oxygen species GO:0000302 56 0.118
inner mitochondrial membrane organization GO:0007007 5 0.110
ribose phosphate metabolic process GO:0019693 291 0.105
protein transmembrane transport GO:0071806 8 0.101
coenzyme biosynthetic process GO:0009108 23 0.097
protein localization to mitochondrion GO:0070585 15 0.095
defense response to other organism GO:0098542 197 0.094
oxidation reduction process GO:0055114 342 0.094
cell type specific apoptotic process GO:0097285 268 0.091
cristae formation GO:0042407 3 0.087
membrane organization GO:0061024 245 0.085
adaptive immune response GO:0002250 155 0.082
regulation of feeding behavior GO:0060259 3 0.082
regulation of membrane potential GO:0042391 192 0.079
aromatic compound catabolic process GO:0019439 286 0.076
regulation of cellular ketone metabolic process GO:0010565 66 0.075
dna metabolic process GO:0006259 303 0.075
mitochondrion morphogenesis GO:0070584 13 0.069
atp metabolic process GO:0046034 75 0.068
transmembrane transport GO:0055085 412 0.067
trna aminoacylation for protein translation GO:0006418 1 0.067
cellular amino acid metabolic process GO:0006520 103 0.067
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.066
regulation of dna catabolic process GO:1903624 5 0.066
purine nucleoside monophosphate metabolic process GO:0009126 81 0.066
purine nucleotide metabolic process GO:0006163 302 0.064
cellular respiration GO:0045333 38 0.063
regulation of organelle organization GO:0033043 289 0.063
cellular nitrogen compound catabolic process GO:0044270 280 0.062
establishment of protein localization to mitochondrion GO:0072655 11 0.060
purine ribonucleoside metabolic process GO:0046128 241 0.059
protein targeting GO:0006605 143 0.058
glycosyl compound metabolic process GO:1901657 246 0.053
mitochondrial fusion GO:0008053 9 0.051
protein catabolic process GO:0030163 221 0.049
protein processing GO:0016485 163 0.048
positive regulation of interferon alpha production GO:0032727 4 0.048
protein localization to organelle GO:0033365 185 0.046
organelle disassembly GO:1903008 2 0.045
autophagy GO:0006914 45 0.045
cytoplasmic transport GO:0016482 234 0.045
intracellular protein transport GO:0006886 204 0.044
ion transmembrane transport GO:0034220 361 0.044
response to organonitrogen compound GO:0010243 246 0.043
wound healing GO:0042060 157 0.042
cellular ketone metabolic process GO:0042180 84 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
mitochondrion degradation GO:0000422 3 0.039
posttranscriptional regulation of gene expression GO:0010608 155 0.038
protein import GO:0017038 101 0.038
synapse organization GO:0050808 125 0.038
protein export from nucleus GO:0006611 20 0.037
endocytosis GO:0006897 168 0.037
ribonucleotide metabolic process GO:0009259 291 0.037
positive regulation of lymphocyte activation GO:0051251 140 0.037
action potential GO:0001508 78 0.036
dna catabolic process GO:0006308 19 0.035
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
cytokine production GO:0001816 319 0.034
nucleoside metabolic process GO:0009116 246 0.034
regulation of translation GO:0006417 71 0.034
membrane fusion GO:0061025 38 0.034
cellular protein complex assembly GO:0043623 116 0.034
response to inorganic substance GO:0010035 96 0.033
intrinsic apoptotic signaling pathway GO:0097193 132 0.033
ribonucleoside monophosphate metabolic process GO:0009161 80 0.033
amine metabolic process GO:0009308 45 0.033
translation GO:0006412 93 0.033
nuclear export GO:0051168 34 0.033
multicellular organismal homeostasis GO:0048871 164 0.032
maintenance of location GO:0051235 89 0.032
establishment of protein localization to organelle GO:0072594 118 0.032
nitrogen compound transport GO:0071705 271 0.031
positive regulation of t cell activation GO:0050870 101 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.031
lymphocyte proliferation GO:0046651 164 0.031
positive regulation of cell activation GO:0050867 158 0.031
negative regulation of molecular function GO:0044092 258 0.031
gland development GO:0048732 330 0.030
nucleoside monophosphate metabolic process GO:0009123 85 0.030
positive regulation of immune effector process GO:0002699 107 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
cation transmembrane transport GO:0098655 266 0.028
regulation of neuron death GO:1901214 134 0.028
immune effector process GO:0002252 321 0.028
renal system development GO:0072001 225 0.027
positive regulation of mitochondrion organization GO:0010822 17 0.027
macromolecule glycosylation GO:0043413 55 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
negative regulation of dna replication GO:0008156 4 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
cytokine production involved in immune response GO:0002367 34 0.026
urogenital system development GO:0001655 261 0.026
macromolecule catabolic process GO:0009057 281 0.026
cellular response to inorganic substance GO:0071241 37 0.025
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
purine ribonucleotide biosynthetic process GO:0009152 59 0.025
epithelial tube morphogenesis GO:0060562 303 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
protein maturation GO:0051604 176 0.025
myelination GO:0042552 74 0.025
type i interferon production GO:0032606 29 0.025
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.024
neuron death GO:0070997 154 0.024
cellular amide metabolic process GO:0043603 58 0.024
response to heat GO:0009408 27 0.024
purine containing compound metabolic process GO:0072521 311 0.024
cation transport GO:0006812 399 0.023
regulation of cell activation GO:0050865 289 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
positive regulation of immune response to tumor cell GO:0002839 6 0.023
defense response to bacterium GO:0042742 119 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
purine nucleotide catabolic process GO:0006195 211 0.023
regulation of defense response GO:0031347 233 0.022
divalent metal ion transport GO:0070838 172 0.022
locomotory behavior GO:0007626 195 0.022
transmission of nerve impulse GO:0019226 76 0.021
positive regulation of type i interferon production GO:0032481 14 0.021
cajal body organization GO:0030576 1 0.021
antimicrobial peptide production GO:0002775 2 0.021
apoptotic signaling pathway GO:0097190 306 0.021
nuclear transport GO:0051169 139 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
response to temperature stimulus GO:0009266 55 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
cellular homeostasis GO:0019725 240 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
leukocyte proliferation GO:0070661 172 0.020
muscle cell differentiation GO:0042692 261 0.020
regulation of mitochondrial fission GO:0090140 3 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
purine nucleotide biosynthetic process GO:0006164 65 0.020
mitochondrial protein processing GO:0034982 5 0.020
divalent inorganic cation transport GO:0072511 178 0.020
negative regulation of cell cycle phase transition GO:1901988 48 0.020
acyl coa biosynthetic process GO:0071616 7 0.020
anatomical structure homeostasis GO:0060249 145 0.020
angiogenesis GO:0001525 201 0.019
lateral inhibition GO:0046331 1 0.019
cation homeostasis GO:0055080 212 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
response to peptide hormone GO:0043434 127 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
positive regulation of nervous system development GO:0051962 221 0.019
er nucleus signaling pathway GO:0006984 27 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
neuronal action potential GO:0019228 54 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
cofactor biosynthetic process GO:0051188 41 0.018
cell aging GO:0007569 35 0.018
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.018
immunoglobulin production GO:0002377 73 0.018
tissue homeostasis GO:0001894 115 0.018
ribonucleotide biosynthetic process GO:0009260 59 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
cell activation involved in immune response GO:0002263 126 0.017
ossification GO:0001503 216 0.017
peptidyl amino acid modification GO:0018193 336 0.017
multicellular organismal aging GO:0010259 24 0.017
cellular amine metabolic process GO:0044106 44 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
regulation of cytokine production GO:0001817 266 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
calcium ion transport GO:0006816 159 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
nucleoside catabolic process GO:0009164 206 0.016
regulation of macrophage activation GO:0043030 17 0.016
response to oxygen radical GO:0000305 16 0.016
regulation of homeostatic process GO:0032844 182 0.016
response to epidermal growth factor GO:0070849 4 0.016
lipid localization GO:0010876 126 0.016
lymphocyte mediated immunity GO:0002449 139 0.015
trna metabolic process GO:0006399 11 0.015
somatic diversification of immune receptors GO:0002200 53 0.015
acetyl coa biosynthetic process GO:0006085 5 0.015
sulfur compound metabolic process GO:0006790 100 0.015
leukocyte mediated immunity GO:0002443 174 0.015
positive regulation of cell development GO:0010720 237 0.015
ribonucleoside monophosphate catabolic process GO:0009158 57 0.015
organelle fusion GO:0048284 28 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
adult behavior GO:0030534 135 0.014
regulation of hydrolase activity GO:0051336 246 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
regulation of anatomical structure size GO:0090066 178 0.014
metal ion homeostasis GO:0055065 189 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
macrophage activation GO:0042116 27 0.014
tube formation GO:0035148 140 0.014
multicellular organismal signaling GO:0035637 91 0.014
immunoglobulin mediated immune response GO:0016064 69 0.014
ensheathment of neurons GO:0007272 76 0.014
metaphase plate congression GO:0051310 2 0.014
regulation of binding GO:0051098 111 0.014
regulation of ion transport GO:0043269 215 0.013
male gamete generation GO:0048232 285 0.013
regulation of adaptive immune response GO:0002819 90 0.013
lipid biosynthetic process GO:0008610 179 0.013
cellular chemical homeostasis GO:0055082 215 0.013
macromolecule methylation GO:0043414 120 0.013
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.013
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.013
cellular response to heat GO:0034605 15 0.013
multicellular organism growth GO:0035264 161 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
detection of stimulus GO:0051606 84 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
regulation of antimicrobial peptide production GO:0002784 1 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
response to topologically incorrect protein GO:0035966 25 0.013
response to peptide GO:1901652 136 0.013
regulation of angiogenesis GO:0045765 81 0.013
protein localization to membrane GO:0072657 108 0.013
positive regulation of growth GO:0045927 104 0.013
t cell mediated immunity GO:0002456 50 0.013
antibacterial peptide production GO:0002778 2 0.013
cellular response to arsenic containing substance GO:0071243 4 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
muscle tissue development GO:0060537 308 0.012
dna recombination GO:0006310 92 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
regulation of transmembrane transport GO:0034762 128 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of protein catabolic process GO:0042176 108 0.012
blastocyst development GO:0001824 80 0.012
nerve development GO:0021675 67 0.012
response to increased oxygen levels GO:0036296 2 0.012
response to organic cyclic compound GO:0014070 198 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
response to extracellular stimulus GO:0009991 127 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
postsynaptic membrane organization GO:0001941 18 0.012
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.012
oocyte maturation GO:0001556 18 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
nucleotide catabolic process GO:0009166 217 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
sensory perception GO:0007600 245 0.012
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of macrophage activation GO:0043032 10 0.011
regulation of response to biotic stimulus GO:0002831 38 0.011
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.011
carbohydrate homeostasis GO:0033500 128 0.011
neural precursor cell proliferation GO:0061351 121 0.011
regulation of protein oligomerization GO:0032459 4 0.011
activation of immune response GO:0002253 138 0.011
regulation of proteolysis GO:0030162 164 0.011
myeloid cell differentiation GO:0030099 233 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
anion transport GO:0006820 177 0.011
regulation of response to tumor cell GO:0002834 6 0.011
epithelial cell proliferation GO:0050673 174 0.011
b cell mediated immunity GO:0019724 71 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
positive regulation of leukocyte mediated immunity GO:0002705 70 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
axon ensheathment GO:0008366 76 0.011
quinone biosynthetic process GO:1901663 4 0.011
rna interference GO:0016246 2 0.011
hexose biosynthetic process GO:0019319 39 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
cellular response to cadmium ion GO:0071276 3 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
cell growth GO:0016049 130 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
actin cytoskeleton organization GO:0030036 220 0.011
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.011
negative regulation of neuron death GO:1901215 98 0.011
small molecule biosynthetic process GO:0044283 132 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
dna catabolic process endonucleolytic GO:0000737 15 0.011
nucleotide metabolic process GO:0009117 332 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
response to hyperoxia GO:0055093 2 0.010
toll like receptor signaling pathway GO:0002224 38 0.010
amino acid activation GO:0043038 1 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
cellular amino acid catabolic process GO:0009063 25 0.010
regulation of gluconeogenesis GO:0006111 30 0.010
leukocyte differentiation GO:0002521 342 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
regulation of antimicrobial humoral response GO:0002759 3 0.010
dendrite development GO:0016358 115 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
muscle cell development GO:0055001 133 0.010
chromatin modification GO:0016568 187 0.010
cellular response to calcium ion GO:0071277 14 0.010

Lrpprc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.060
disease of cellular proliferation DOID:14566 0 0.060
disease of anatomical entity DOID:7 0 0.051
nervous system disease DOID:863 0 0.051
disease of metabolism DOID:0014667 0 0.043
amino acid metabolic disorder DOID:9252 0 0.043
inherited metabolic disorder DOID:655 0 0.043
central nervous system disease DOID:331 0 0.035
neurodegenerative disease DOID:1289 0 0.035
organ system cancer DOID:0050686 0 0.021
organic acidemia DOID:0060159 0 0.017
paraplegia DOID:607 0 0.014
hereditary spastic paraplegia DOID:2476 0 0.014