Mus musculus

111 known processes

Nos2

nitric oxide synthase 2, inducible

(Aliases: NOS-II,iNOS,Nos-2,Nos2a,i-NOS)

Nos2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of programmed cell death GO:0043068 218 0.998
Rat
response to lipopolysaccharide GO:0032496 128 0.995
cellular amino acid metabolic process GO:0006520 103 0.986
defense response to other organism GO:0098542 197 0.983
cellular response to lipid GO:0071396 145 0.978
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.977
reactive oxygen species biosynthetic process GO:1903409 8 0.976
regulation of cellular amine metabolic process GO:0033238 20 0.975
nitric oxide biosynthetic process GO:0006809 25 0.974
extrinsic apoptotic signaling pathway GO:0097191 126 0.966
keratinocyte migration GO:0051546 3 0.957
positive regulation of cellular amine metabolic process GO:0033240 5 0.957
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.953
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.946
positive regulation of apoptotic process GO:0043065 217 0.944
Rat
cellular response to cytokine stimulus GO:0071345 189 0.942
reactive nitrogen species metabolic process GO:2001057 0 0.942
cytokine production GO:0001816 319 0.941
metal ion homeostasis GO:0055065 189 0.938
fever generation GO:0001660 7 0.937
interleukin 13 secretion GO:0072611 2 0.934
nitric oxide metabolic process GO:0046209 25 0.930
regulation of cytokine production GO:0001817 266 0.929
regulation of inflammatory response GO:0050727 147 0.922
cation homeostasis GO:0055080 212 0.922
positive regulation of protein modification process GO:0031401 299 0.913
Mouse
negative regulation of secretion GO:0051048 61 0.910
response to molecule of bacterial origin GO:0002237 143 0.905
regulation of vasculature development GO:1901342 88 0.904
Mouse
leukocyte migration GO:0050900 124 0.903
urogenital system development GO:0001655 261 0.901
morphogenesis of a branching structure GO:0001763 203 0.893
regulation of defense response GO:0031347 233 0.893
regulation of chronic inflammatory response to antigenic stimulus GO:0002874 3 0.892
response to growth factor GO:0070848 198 0.890
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.889
positive regulation of protein phosphorylation GO:0001934 242 0.887
antibacterial peptide secretion GO:0002779 1 0.884
positive regulation of cell death GO:0010942 224 0.880
Rat
amine metabolic process GO:0009308 45 0.879
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.878
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.878
leukocyte mediated immunity GO:0002443 174 0.878
regulation of peptidyl serine phosphorylation GO:0033135 39 0.875
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.865
response to defenses of other organism involved in symbiotic interaction GO:0052173 3 0.863
regulation of secretion GO:0051046 274 0.858
organic anion transport GO:0015711 137 0.857
negative regulation of interleukin 5 production GO:0032714 4 0.853
leukocyte differentiation GO:0002521 342 0.852
modification of morphology or physiology of other organism GO:0035821 18 0.852
angiogenesis GO:0001525 201 0.850
Mouse
regulation of cytokine production involved in immune response GO:0002718 26 0.848
nephron tubule development GO:0072080 84 0.831
negative regulation of cell proliferation GO:0008285 296 0.829
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.827
positive regulation of leukocyte mediated immunity GO:0002705 70 0.823
regulation of renal output by angiotensin GO:0002019 2 0.817
positive regulation of apoptotic signaling pathway GO:2001235 95 0.816
peptidyl tyrosine phosphorylation GO:0018108 143 0.815
fatty acid transport GO:0015908 28 0.812
organic acid transport GO:0015849 101 0.811
negative regulation of interleukin 5 secretion GO:2000663 1 0.808
interleukin 5 secretion GO:0072603 2 0.808
peptidyl tyrosine modification GO:0018212 145 0.807
regulation of establishment of protein localization GO:0070201 181 0.806
lymphocyte migration GO:0072676 26 0.803
regulation of angiogenesis GO:0045765 81 0.802
Mouse
regulation of secretion by cell GO:1903530 249 0.799
antibacterial peptide production GO:0002778 2 0.790
placenta development GO:0001890 140 0.786
neuronal action potential GO:0019228 54 0.777
positive regulation of lymphocyte proliferation GO:0050671 70 0.776
regulation of acute inflammatory response GO:0002673 27 0.774
regulation of cell migration GO:0030334 219 0.769
positive regulation of secretion GO:0051047 130 0.767
positive regulation of defense response GO:0031349 124 0.766
positive regulation of cell development GO:0010720 237 0.759
modulation by virus of host morphology or physiology GO:0019048 3 0.754
carboxylic acid transport GO:0046942 100 0.754
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.746
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.746
positive regulation of leukocyte proliferation GO:0070665 73 0.742
kidney epithelium development GO:0072073 121 0.742
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.741
interspecies interaction between organisms GO:0044419 83 0.741
apoptotic signaling pathway GO:0097190 306 0.734
regulation of cell activation GO:0050865 289 0.733
regulation of cellular amino acid metabolic process GO:0006521 5 0.731
divalent metal ion transport GO:0070838 172 0.729
Mouse
positive regulation of kinase activity GO:0033674 155 0.728
negative regulation of interleukin 13 secretion GO:2000666 1 0.728
cell chemotaxis GO:0060326 81 0.726
muscle contraction GO:0006936 101 0.714
Mouse
cellular amine metabolic process GO:0044106 44 0.714
positive regulation of mapk cascade GO:0043410 170 0.713
positive regulation of protein secretion GO:0050714 52 0.709
peptide secretion GO:0002790 114 0.708
cellular response to organonitrogen compound GO:0071417 145 0.708
t cell activation GO:0042110 289 0.701
calcium ion transport GO:0006816 159 0.700
Mouse
response to oxygen levels GO:0070482 62 0.698
action potential GO:0001508 78 0.698
cellular ketone metabolic process GO:0042180 84 0.697
regulation of protein transport GO:0051223 163 0.690
regulation of apoptotic signaling pathway GO:2001233 197 0.690
defense response to gram negative bacterium GO:0050829 28 0.689
Rat
negative regulation of interleukin 13 production GO:0032696 2 0.686
regulation of cellular ketone metabolic process GO:0010565 66 0.683
negative regulation of hormone secretion GO:0046888 20 0.678
immune effector process GO:0002252 321 0.678
positive regulation of t cell proliferation GO:0042102 52 0.676
negative regulation of macrophage apoptotic process GO:2000110 3 0.675
cellular chemical homeostasis GO:0055082 215 0.674
divalent inorganic cation homeostasis GO:0072507 138 0.672
cellular calcium ion homeostasis GO:0006874 119 0.672
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.665
cytokine secretion GO:0050663 72 0.662
cellular response to molecule of bacterial origin GO:0071219 83 0.661
regulation of leukocyte mediated immunity GO:0002703 104 0.654
internal protein amino acid acetylation GO:0006475 42 0.651
Mouse
response to hypoxia GO:0001666 58 0.649
regulation of blood pressure GO:0008217 93 0.647
Rat
cellular response to lipopolysaccharide GO:0071222 77 0.645
erk1 and erk2 cascade GO:0070371 77 0.645
skin development GO:0043588 220 0.644
muscle adaptation GO:0043500 39 0.644
Mouse
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.644
peptide transport GO:0015833 133 0.643
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.633
negative regulation of secretion by cell GO:1903531 54 0.633
regulation of peptide transport GO:0090087 91 0.632
regulation of growth of symbiont in host GO:0044126 19 0.632
transmission of nerve impulse GO:0019226 76 0.624
response to peptide hormone GO:0043434 127 0.623
positive regulation of cell activation GO:0050867 158 0.622
heat generation GO:0031649 13 0.620
modification by symbiont of host morphology or physiology GO:0044003 4 0.618
regulation of ion transport GO:0043269 215 0.618
Mouse
developmental maturation GO:0021700 193 0.613
regulation of nitric oxide biosynthetic process GO:0045428 18 0.608
multicellular organismal signaling GO:0035637 91 0.602
positive regulation of b cell proliferation GO:0030890 24 0.599
positive regulation of protein transport GO:0051222 93 0.594
leukocyte activation involved in immune response GO:0002366 126 0.592
anion transport GO:0006820 177 0.587
myeloid leukocyte migration GO:0097529 57 0.584
positive regulation of cell migration GO:0030335 109 0.581
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.581
production of molecular mediator of immune response GO:0002440 103 0.575
positive regulation of leukocyte differentiation GO:1902107 86 0.566
regulation of interleukin 13 secretion GO:2000665 2 0.562
positive regulation of histone acetylation GO:0035066 8 0.561
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.549
microglial cell activation involved in immune response GO:0002282 1 0.537
negative regulation of phosphate metabolic process GO:0045936 184 0.537
reactive oxygen species metabolic process GO:0072593 84 0.537
regulation of lymphocyte activation GO:0051249 240 0.530
negative regulation of interleukin 10 secretion GO:2001180 2 0.529
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.528
muscle system process GO:0003012 141 0.524
Mouse
response to organonitrogen compound GO:0010243 246 0.523
response to amphetamine GO:0001975 16 0.520
cell substrate adhesion GO:0031589 130 0.520
defense response to gram positive bacterium GO:0050830 50 0.509
regulation of peptidase activity GO:0052547 96 0.508
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.506
negative regulation of protein metabolic process GO:0051248 282 0.506
regulation of protein localization GO:0032880 231 0.505
regulation of cytokine secretion involved in immune response GO:0002739 4 0.505
adaptive immune response GO:0002250 155 0.503
hair follicle development GO:0001942 85 0.503
regulation of interleukin 10 secretion GO:2001179 4 0.502
nitrogen compound transport GO:0071705 271 0.501
Mouse
somatic diversification of immune receptors GO:0002200 53 0.498
regulation of peptide secretion GO:0002791 77 0.497
cellular ion homeostasis GO:0006873 165 0.495
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.491
regulation of cytokine secretion GO:0050707 61 0.491
lymphocyte mediated immunity GO:0002449 139 0.489
muscle cell development GO:0055001 133 0.486
positive regulation of map kinase activity GO:0043406 84 0.484
positive regulation of cytokine secretion GO:0050715 41 0.481
ameboidal type cell migration GO:0001667 128 0.480
interleukin 18 production GO:0032621 4 0.480
histone acetylation GO:0016573 41 0.480
Mouse
cellular response to tumor necrosis factor GO:0071356 21 0.477
Rat
regulation of urea metabolic process GO:0034255 1 0.477
regulation of nitrogen cycle metabolic process GO:1903314 1 0.477
protein localization to nucleus GO:0034504 121 0.476
positive regulation of cell motility GO:2000147 116 0.475
acute phase response GO:0006953 10 0.472
peptidyl amino acid modification GO:0018193 336 0.469
cellular divalent inorganic cation homeostasis GO:0072503 127 0.468
calcium ion homeostasis GO:0055074 127 0.467
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.464
cation transport GO:0006812 399 0.463
Mouse
protein kinase b signaling GO:0043491 74 0.462
regulation of phospholipase c activity GO:1900274 3 0.461
regulation of hormone levels GO:0010817 211 0.461
cellular response to external stimulus GO:0071496 88 0.459
Rat
negative regulation of calcium ion transport GO:0051926 9 0.458
Mouse
lymphocyte differentiation GO:0030098 242 0.457
tissue migration GO:0090130 68 0.457
epithelial tube morphogenesis GO:0060562 303 0.456
myeloid leukocyte activation GO:0002274 83 0.456
maternal process involved in female pregnancy GO:0060135 32 0.453
renal tubule development GO:0061326 87 0.453
tyrosine phosphorylation of stat protein GO:0007260 23 0.451
renin angiotensin regulation of aldosterone production GO:0002018 3 0.450
response to interleukin 1 GO:0070555 11 0.450
Rat
positive regulation of response to wounding GO:1903036 66 0.446
regulation of kinase activity GO:0043549 249 0.442
Rat
regulation of heat generation GO:0031650 8 0.441
hair cycle GO:0042633 90 0.440
regulation of transferase activity GO:0051338 263 0.437
Rat
acid secretion GO:0046717 33 0.432
negative regulation of inflammatory response GO:0050728 61 0.431
growth of symbiont involved in interaction with host GO:0044116 23 0.430
cell fate commitment GO:0045165 210 0.429
cellular response to acid chemical GO:0071229 68 0.428
granulocyte migration GO:0097530 43 0.427
antimicrobial peptide secretion GO:0002776 1 0.424
regulation of b cell activation GO:0050864 81 0.424
dna metabolic process GO:0006259 303 0.423
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.419
amide transport GO:0042886 138 0.418
positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 2 0.416
inflammatory response GO:0006954 244 0.415
regulation of protein secretion GO:0050708 82 0.415
striated muscle tissue development GO:0014706 293 0.412
epidermis development GO:0008544 187 0.410
regulation of leukocyte differentiation GO:1902105 159 0.409
molting cycle GO:0042303 90 0.409
regulation of cell motility GO:2000145 236 0.409
negative regulation of cellular protein metabolic process GO:0032269 247 0.407
negative regulation of interferon gamma production GO:0032689 18 0.402
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.402
regulation of response to wounding GO:1903034 189 0.401
response to lithium ion GO:0010226 10 0.400
Rat
integrin mediated signaling pathway GO:0007229 27 0.398
monocarboxylic acid transport GO:0015718 44 0.398
negative regulation of growth GO:0045926 99 0.396
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.392
metanephros development GO:0001656 79 0.389
cytokine mediated signaling pathway GO:0019221 115 0.389
cellular response to biotic stimulus GO:0071216 92 0.387
myotube differentiation GO:0014902 105 0.385
multicellular organismal homeostasis GO:0048871 164 0.385
production of molecular mediator involved in inflammatory response GO:0002532 21 0.385
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.379
regulation of innate immune response GO:0045088 91 0.379
glial cell differentiation GO:0010001 131 0.378
chemotaxis GO:0006935 247 0.376
developmental growth involved in morphogenesis GO:0060560 138 0.372
dna recombination GO:0006310 92 0.371
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.369
regulation of histone acetylation GO:0035065 19 0.367
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.367
regulation of lymphocyte proliferation GO:0050670 117 0.365
regulation of striated muscle cell differentiation GO:0051153 81 0.365
myeloid leukocyte differentiation GO:0002573 119 0.364
regulation of fatty acid transport GO:2000191 10 0.364
regulation of chromatin modification GO:1903308 57 0.363
Mouse
brown fat cell differentiation GO:0050873 36 0.361
striated muscle cell development GO:0055002 125 0.360
t cell extravasation GO:0072683 4 0.359
regulation of homeostatic process GO:0032844 182 0.359
odontogenesis GO:0042476 78 0.358
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.358
regulation of vitamin d biosynthetic process GO:0060556 1 0.356
serine phosphorylation of stat protein GO:0042501 3 0.355
response to alcohol GO:0097305 48 0.354
Rat
rhythmic process GO:0048511 174 0.353
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.351
lipid transport GO:0006869 98 0.351
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.350
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.348
regulation of membrane potential GO:0042391 192 0.347
histone modification GO:0016570 159 0.345
Mouse
acute inflammatory response GO:0002526 41 0.345
cellular metal ion homeostasis GO:0006875 151 0.343
regulation of t cell activation GO:0050863 170 0.342
response to hyperoxia GO:0055093 2 0.340
sensory perception GO:0007600 245 0.339
positive regulation of acute inflammatory response GO:0002675 16 0.339
response to bile acid GO:1903412 1 0.334
positive regulation of inflammatory response GO:0050729 47 0.332
inflammatory response to wounding GO:0090594 4 0.332
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.332
regulation of glial cell differentiation GO:0045685 41 0.332
intracellular receptor signaling pathway GO:0030522 74 0.331
Rat
signal transduction by p53 class mediator GO:0072331 51 0.331
positive regulation of b cell mediated immunity GO:0002714 26 0.328
salivary gland development GO:0007431 37 0.328
protein secretion GO:0009306 111 0.327
decidualization GO:0046697 10 0.326
temperature homeostasis GO:0001659 26 0.325
negative regulation of angiogenesis GO:0016525 25 0.324
blood vessel morphogenesis GO:0048514 285 0.323
Mouse
regulation of fat cell differentiation GO:0045598 81 0.320
positive regulation of chronic inflammatory response GO:0002678 4 0.317
positive regulation of nervous system development GO:0051962 221 0.317
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.316
regulation of interleukin 5 secretion GO:2000662 2 0.316
positive regulation of t cell activation GO:0050870 101 0.315
multi multicellular organism process GO:0044706 109 0.314
regulation of protein kinase activity GO:0045859 232 0.313
Rat
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 1 0.312
morphogenesis of a branching epithelium GO:0061138 193 0.312
fibroblast growth factor production GO:0090269 4 0.310
cytokine production involved in immune response GO:0002367 34 0.310
hemostasis GO:0007599 78 0.306
modulation by symbiont of defense related host nitric oxide production GO:0052163 1 0.306
regulation of mapk cascade GO:0043408 248 0.305
positive regulation of immune effector process GO:0002699 107 0.305
peptidyl serine phosphorylation GO:0018105 74 0.304
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.302
sensory perception of pain GO:0019233 47 0.301
divalent inorganic cation transport GO:0072511 178 0.300
Mouse
response to host defenses GO:0052200 3 0.300
metanephric nephron development GO:0072210 34 0.300
growth involved in symbiotic interaction GO:0044110 23 0.297
i kappab kinase nf kappab signaling GO:0007249 85 0.296
regulation of immunoglobulin production GO:0002637 42 0.296
regulation of kidney development GO:0090183 40 0.296
peptide hormone secretion GO:0030072 109 0.293
interleukin 10 secretion GO:0072608 4 0.290
positive regulation of fever generation GO:0031622 6 0.288
negative regulation of apoptotic signaling pathway GO:2001234 104 0.286
response to decreased oxygen levels GO:0036293 59 0.286
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.285
branching involved in salivary gland morphogenesis GO:0060445 26 0.283
fat cell differentiation GO:0045444 160 0.283
b cell proliferation GO:0042100 53 0.282
negative regulation of odontogenesis of dentin containing tooth GO:0042489 1 0.280
positive regulation of mhc class ii biosynthetic process GO:0045348 4 0.280
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1990127 1 0.279
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.277
negative regulation of cytokine production GO:0001818 84 0.276
interleukin 18 mediated signaling pathway GO:0035655 2 0.276
mammary gland duct morphogenesis GO:0060603 38 0.275
t cell differentiation GO:0030217 174 0.273
ensheathment of neurons GO:0007272 76 0.272
myelination GO:0042552 74 0.272
cellular response to growth factor stimulus GO:0071363 197 0.269
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.269
positive regulation of cytoplasmic transport GO:1903651 40 0.266
regulation of mhc class ii biosynthetic process GO:0045346 7 0.265
peptidyl serine modification GO:0018209 83 0.265
regulation of fever generation GO:0031620 6 0.264
lymphocyte activation involved in immune response GO:0002285 93 0.261
wound healing GO:0042060 157 0.259
Rat
positive regulation of jak stat cascade GO:0046427 22 0.259
cell type specific apoptotic process GO:0097285 268 0.257
covalent chromatin modification GO:0016569 163 0.257
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.257
response to extracellular stimulus GO:0009991 127 0.257
Rat
nephron epithelium morphogenesis GO:0072088 68 0.256
negative regulation of phosphorylation GO:0042326 166 0.253
synaptic transmission GO:0007268 329 0.250
Mouse
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.248
leukocyte proliferation GO:0070661 172 0.245
regulation of b cell proliferation GO:0030888 39 0.245
regulation of interleukin 18 production GO:0032661 3 0.245
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.239
response to corticosterone GO:0051412 1 0.238
positive regulation of secretion by cell GO:1903532 114 0.237
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.237
regulation of chronic inflammatory response GO:0002676 7 0.237
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.235
organic hydroxy compound metabolic process GO:1901615 203 0.235
positive regulation of renal sodium excretion GO:0035815 2 0.235
cellular response to amino acid stimulus GO:0071230 29 0.234
regulation of histone modification GO:0031056 56 0.233
Mouse
cellular response to interleukin 18 GO:0071351 3 0.231
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.231
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 15 0.228
neuron death GO:0070997 154 0.224
transdifferentiation GO:0060290 1 0.223
cellular extravasation GO:0045123 17 0.222
coagulation GO:0050817 78 0.222
regulation of interferon gamma production GO:0032649 57 0.219
defense response to bacterium GO:0042742 119 0.217
osteoclast differentiation GO:0030316 62 0.217
positive regulation of t cell costimulation GO:2000525 2 0.216
icosanoid secretion GO:0032309 12 0.215
cellular response to peptide GO:1901653 92 0.215
response to acid chemical GO:0001101 111 0.214
cell activation involved in immune response GO:0002263 126 0.214
gland development GO:0048732 330 0.213
positive regulation of lymphocyte activation GO:0051251 140 0.212
positive regulation of synaptic plasticity GO:0031915 4 0.211
positive regulation of kidney development GO:0090184 28 0.211
neuron apoptotic process GO:0051402 142 0.211
positive regulation of glial cell proliferation GO:0060252 4 0.210
response to fatty acid GO:0070542 8 0.210
positive regulation of protein localization to nucleus GO:1900182 30 0.209
regulation of ion homeostasis GO:2000021 64 0.206
b cell activation involved in immune response GO:0002312 50 0.205
response to retinoic acid GO:0032526 56 0.205
positive regulation of intracellular transport GO:0032388 70 0.205
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070430 1 0.203
female gamete generation GO:0007292 74 0.201
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.200
positive regulation of hydrolase activity GO:0051345 148 0.198
small gtpase mediated signal transduction GO:0007264 97 0.198
negative regulation of myoblast differentiation GO:0045662 18 0.197
regulation of protein import into nucleus GO:0042306 52 0.196
positive regulation of angiogenesis GO:0045766 46 0.196
Mouse
negative regulation of multi organism process GO:0043901 68 0.195
response to iron ion GO:0010039 4 0.194
regulation of organ morphogenesis GO:2000027 144 0.193
regulation of glutamate metabolic process GO:2000211 1 0.193
protein localization to organelle GO:0033365 185 0.192
glial cell apoptotic process GO:0034349 3 0.191
cellular response to abiotic stimulus GO:0071214 56 0.191
gliogenesis GO:0042063 141 0.190
negative regulation of cell development GO:0010721 169 0.189
negative regulation of protein processing GO:0010955 79 0.188
positive regulation of t cell migration GO:2000406 10 0.187
axon ensheathment GO:0008366 76 0.187
regulation of calcium ion transport GO:0051924 69 0.186
Mouse
negative regulation of protein modification process GO:0031400 163 0.186
regulation of metal ion transport GO:0010959 106 0.186
Mouse
regulation of odontogenesis GO:0042481 18 0.185
dendrite development GO:0016358 115 0.184
salivary gland morphogenesis GO:0007435 33 0.184
regulation of endopeptidase activity GO:0052548 89 0.184
regulation of hormone secretion GO:0046883 88 0.183
positive regulation of homeostatic process GO:0032846 64 0.182
antibacterial peptide biosynthetic process GO:0002780 2 0.182
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.179
positive regulation of neuron differentiation GO:0045666 141 0.179
metanephros morphogenesis GO:0003338 24 0.178
positive regulation of cytokine production GO:0001819 174 0.178
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.178
positive regulation of transcription factor import into nucleus GO:0042993 8 0.177
t cell migration GO:0072678 19 0.177
interleukin 6 production GO:0032635 58 0.176
g protein coupled receptor signaling pathway GO:0007186 243 0.175
Mouse Rat
regulation of protein acetylation GO:1901983 22 0.174
Mouse
negative regulation of defense response GO:0031348 77 0.174
camera type eye development GO:0043010 266 0.172
regulation of cell projection organization GO:0031344 206 0.172
regulation of gliogenesis GO:0014013 50 0.171
rho protein signal transduction GO:0007266 32 0.171
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.170
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 13 0.169
gonad development GO:0008406 141 0.168
Mouse
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.168
regulation of nucleocytoplasmic transport GO:0046822 73 0.168
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.167
glutamate metabolic process GO:0006536 9 0.166
purine ribonucleotide metabolic process GO:0009150 290 0.165
detection of molecule of bacterial origin GO:0032490 2 0.164
glutamine family amino acid metabolic process GO:0009064 15 0.164
muscle cell differentiation GO:0042692 261 0.164
sequestering of metal ion GO:0051238 19 0.162
positive regulation of protein acetylation GO:1901985 9 0.162
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.161
hair cycle phase GO:0044851 16 0.161
renal system process GO:0003014 48 0.160
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.159
cytokine secretion involved in immune response GO:0002374 6 0.158
response to steroid hormone GO:0048545 56 0.158
Rat
cellular response to catecholamine stimulus GO:0071870 3 0.157
circulatory system process GO:0003013 197 0.157
Mouse Rat
internal peptidyl lysine acetylation GO:0018393 42 0.157
Mouse
immune complex clearance by monocytes and macrophages GO:0002436 2 0.155
positive regulation of interleukin 18 production GO:0032741 2 0.155
positive regulation of transferase activity GO:0051347 167 0.155
positive regulation of phospholipase activity GO:0010518 3 0.153
regulation of myeloid leukocyte differentiation GO:0002761 58 0.152
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.152
regulation of reactive oxygen species metabolic process GO:2000377 40 0.152
chronic inflammatory response GO:0002544 9 0.152
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.151
regulation of lymphocyte mediated immunity GO:0002706 84 0.150
regulation of chromatin organization GO:1902275 57 0.150
Mouse
positive regulation of organelle organization GO:0010638 128 0.150
Mouse
regulation of b cell mediated immunity GO:0002712 37 0.150
vascular process in circulatory system GO:0003018 62 0.149
Mouse
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.149
Mouse
response to estrogen GO:0043627 24 0.149
Rat
negative regulation of ion transport GO:0043271 28 0.148
Mouse
ras protein signal transduction GO:0007265 77 0.148
response to radiation GO:0009314 165 0.147
regulation of wound healing GO:0061041 40 0.146
negative regulation of lymphocyte proliferation GO:0050672 45 0.145
regulation of vascular endothelial growth factor production GO:0010574 13 0.145
regulation of neuron apoptotic process GO:0043523 122 0.145
b cell activation GO:0042113 161 0.144
response to nicotine GO:0035094 6 0.143
chemokine production GO:0032602 34 0.143
vascular endothelial growth factor production GO:0010573 13 0.142
organonitrogen compound biosynthetic process GO:1901566 192 0.142
regulation of osteoclast differentiation GO:0045670 36 0.142
endocrine system development GO:0035270 98 0.141
regulation of peptide hormone secretion GO:0090276 75 0.141

Nos2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org