Mus musculus

170 known processes

Nos3

nitric oxide synthase 3, endothelial cell

(Aliases: 2310065A03Rik,eNOS,Nos-3,ecNOS)

Nos3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
metanephric glomerular mesangium development GO:0072223 3 1.000
urogenital system development GO:0001655 261 1.000
kidney development GO:0001822 213 1.000
vascular process in circulatory system GO:0003018 62 1.000
mesonephric tubule development GO:0072164 94 1.000
branching morphogenesis of an epithelial tube GO:0048754 159 1.000
cardiocyte differentiation GO:0035051 87 1.000
circulatory system process GO:0003013 197 1.000
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.999
rhythmic process GO:0048511 174 0.999
cardiac cell development GO:0055006 41 0.999
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.999
neuron projection guidance GO:0097485 141 0.999
vasodilation GO:0042311 28 0.999
ovarian follicle development GO:0001541 40 0.999
superoxide metabolic process GO:0006801 27 0.999
Mouse
ureteric bud development GO:0001657 94 0.999
response to peptide hormone GO:0043434 127 0.998
Rat
response to organonitrogen compound GO:0010243 246 0.998
Rat
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.998
response to oxygen levels GO:0070482 62 0.998
Mouse Rat
negative regulation of cell proliferation GO:0008285 296 0.998
regulation of muscle system process GO:0090257 80 0.998
regulation of blood vessel size GO:0050880 56 0.998
response to alcohol GO:0097305 48 0.998
Rat
cell migration involved in coronary angiogenesis GO:0060981 1 0.998
glomerulus development GO:0032835 40 0.998
regulation of cellular ketone metabolic process GO:0010565 66 0.997
development of primary female sexual characteristics GO:0046545 73 0.997
heart trabecula formation GO:0060347 14 0.997
embryonic hemopoiesis GO:0035162 23 0.997
kidney epithelium development GO:0072073 121 0.997
nephron development GO:0072006 109 0.997
regulation of system process GO:0044057 200 0.997
regulation of hormone secretion GO:0046883 88 0.996
regulation of renal output by angiotensin GO:0002019 2 0.996
cardiac muscle cell differentiation GO:0055007 69 0.996
regulation of tube size GO:0035150 57 0.996
regulation of heart contraction GO:0008016 77 0.996
heart process GO:0003015 94 0.996
regulation of peptidyl serine phosphorylation GO:0033135 39 0.996
metanephric glomerular endothelium development GO:0072264 1 0.995
bone development GO:0060348 120 0.995
Rat
metanephric mesenchymal cell migration GO:0035789 2 0.995
muscle adaptation GO:0043500 39 0.995
regulation of blood circulation GO:1903522 93 0.995
blood circulation GO:0008015 195 0.995
regulation of reactive oxygen species metabolic process GO:2000377 40 0.995
negative regulation of systemic arterial blood pressure GO:0003085 15 0.995
regulation of blood pressure GO:0008217 93 0.995
cardiac muscle cell development GO:0055013 39 0.995
purine nucleotide metabolic process GO:0006163 302 0.995
regulation of mesenchymal cell proliferation GO:0010464 37 0.994
regulation of hydrolase activity GO:0051336 246 0.994
response to hypoxia GO:0001666 58 0.994
Mouse Rat
nephron epithelium development GO:0072009 92 0.994
regulation of cellular amino acid metabolic process GO:0006521 5 0.994
coronary vasculature development GO:0060976 12 0.993
metanephric nephron development GO:0072210 34 0.993
erythrocyte differentiation GO:0030218 88 0.993
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.992
blood vessel morphogenesis GO:0048514 285 0.992
negative regulation of cell motility GO:2000146 61 0.991
erythropoietin mediated signaling pathway GO:0038162 1 0.991
axon guidance GO:0007411 141 0.991
cell adhesion GO:0007155 329 0.991
cellular response to erythropoietin GO:0036018 1 0.991
brown fat cell differentiation GO:0050873 36 0.991
positive regulation of smooth muscle cell migration GO:0014911 4 0.990
axonogenesis GO:0007409 274 0.990
cardiac vascular smooth muscle cell development GO:0060948 3 0.990
organonitrogen compound catabolic process GO:1901565 264 0.990
Mouse
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.989
regulation of dna templated transcription in response to stress GO:0043620 9 0.989
epithelial tube morphogenesis GO:0060562 303 0.989
muscle cell differentiation GO:0042692 261 0.987
regulation of cell migration GO:0030334 219 0.987
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.987
angiogenesis GO:0001525 201 0.987
blood vessel remodeling GO:0001974 33 0.986
renal system development GO:0072001 225 0.986
respiratory system development GO:0060541 190 0.986
response to erythropoietin GO:0036017 1 0.986
pro t cell differentiation GO:0002572 3 0.985
cardiac muscle tissue development GO:0048738 130 0.985
lung vasculature development GO:0060426 7 0.985
regulation of cellular amine metabolic process GO:0033238 20 0.985
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.984
muscle tissue development GO:0060537 308 0.984
regulation of the force of heart contraction GO:0002026 17 0.983
development of primary sexual characteristics GO:0045137 143 0.983
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.983
response to peptide GO:1901652 136 0.983
Rat
regulation of cell activation GO:0050865 289 0.983
vasoconstriction GO:0042310 27 0.983
ovulation cycle GO:0042698 59 0.981
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.981
cardiac muscle hypertrophy GO:0003300 23 0.981
response to nutrient levels GO:0031667 109 0.981
regulation of metanephros development GO:0072215 15 0.980
organ growth GO:0035265 117 0.980
amine metabolic process GO:0009308 45 0.980
coronary vasculature morphogenesis GO:0060977 9 0.979
metanephros morphogenesis GO:0003338 24 0.979
regulation of smooth muscle cell migration GO:0014910 6 0.979
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.978
cell type specific apoptotic process GO:0097285 268 0.978
neuron apoptotic process GO:0051402 142 0.978
nucleobase containing small molecule metabolic process GO:0055086 352 0.978
positive regulation of kidney development GO:0090184 28 0.977
cardiac endothelial cell differentiation GO:0003348 4 0.977
cellular response to peptide GO:1901653 92 0.977
regulation of anatomical structure size GO:0090066 178 0.977
negative regulation of cell migration GO:0030336 59 0.976
intestinal absorption GO:0050892 13 0.976
striated muscle tissue development GO:0014706 293 0.976
inositol lipid mediated signaling GO:0048017 41 0.975
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.974
metanephric mesangial cell differentiation GO:0072209 1 0.974
positive regulation of bmp signaling pathway GO:0030513 23 0.973
tissue migration GO:0090130 68 0.973
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.973
positive regulation of growth GO:0045927 104 0.972
positive regulation of cell migration GO:0030335 109 0.972
maternal process involved in female pregnancy GO:0060135 32 0.972
peptidyl amino acid modification GO:0018193 336 0.971
Mouse
metanephric glomerulus development GO:0072224 13 0.971
anatomical structure homeostasis GO:0060249 145 0.971
cardiac muscle fiber development GO:0048739 4 0.970
positive regulation of retinal ganglion cell axon guidance GO:1902336 2 0.970
regulation of nitrogen cycle metabolic process GO:1903314 1 0.970
carbohydrate derivative biosynthetic process GO:1901137 183 0.970
mesonephric epithelium development GO:0072163 94 0.970
renal tubule development GO:0061326 87 0.970
amide transport GO:0042886 138 0.969
foramen ovale closure GO:0035922 1 0.968
ras protein signal transduction GO:0007265 77 0.968
striated muscle hypertrophy GO:0014897 24 0.968
positive regulation of cell motility GO:2000147 116 0.967
regulation of peptide hormone secretion GO:0090276 75 0.967
lung development GO:0030324 164 0.967
glomerular mesangial cell development GO:0072144 3 0.967
positive regulation of mapk cascade GO:0043410 170 0.966
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.966
regulation of peptide transport GO:0090087 91 0.965
positive regulation of axon extension GO:0045773 20 0.965
gonad development GO:0008406 141 0.964
cell proliferation involved in kidney development GO:0072111 14 0.964
bmp signaling pathway GO:0030509 93 0.964
regulation of insulin receptor signaling pathway GO:0046626 21 0.964
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.963
response to hyperoxia GO:0055093 2 0.962
Rat
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1990127 1 0.962
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.962
negative regulation of insulin secretion GO:0046676 14 0.962
cellular response to insulin stimulus GO:0032869 78 0.961
positive regulation of endothelial cell proliferation GO:0001938 17 0.959
digestive tract development GO:0048565 190 0.958
response to decreased oxygen levels GO:0036293 59 0.958
Mouse Rat
regulation of fatty acid metabolic process GO:0019217 28 0.958
regulation of hormone levels GO:0010817 211 0.958
cellular amine metabolic process GO:0044106 44 0.958
cell migration involved in metanephros development GO:0035788 2 0.958
female gamete generation GO:0007292 74 0.957
platelet activation GO:0030168 40 0.957
response to growth factor GO:0070848 198 0.957
Mouse Rat
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.956
camera type eye development GO:0043010 266 0.955
Rat
embryonic heart tube development GO:0035050 65 0.954
embryonic heart tube morphogenesis GO:0003143 51 0.954
cardiac right atrium morphogenesis GO:0003213 3 0.953
female sex differentiation GO:0046660 84 0.953
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.951
hormone secretion GO:0046879 128 0.950
regulation of vasculogenesis GO:2001212 9 0.950
muscle system process GO:0003012 141 0.949
regulation of bmp signaling pathway GO:0030510 60 0.948
lactation GO:0007595 25 0.947
positive regulation of cell death GO:0010942 224 0.947
Rat
renal system process GO:0003014 48 0.946
response to insulin GO:0032868 100 0.946
cellular response to growth factor stimulus GO:0071363 197 0.945
Mouse Rat
bone morphogenesis GO:0060349 78 0.945
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 1 0.945
positive regulation of apoptotic signaling pathway GO:2001235 95 0.944
muscle contraction GO:0006936 101 0.944
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.941
glomerular mesangial cell proliferation GO:0072110 3 0.941
blood vessel endothelial cell migration GO:0043534 23 0.941
glomerular epithelium development GO:0072010 11 0.940
cellular amino acid metabolic process GO:0006520 103 0.940
Mouse
myeloid cell differentiation GO:0030099 233 0.940
nephron tubule development GO:0072080 84 0.939
negative regulation of smooth muscle cell apoptotic process GO:0034392 1 0.938
nephron epithelium morphogenesis GO:0072088 68 0.936
regulation of peptide secretion GO:0002791 77 0.935
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.935
regulation of kidney development GO:0090183 40 0.935
single organismal cell cell adhesion GO:0016337 131 0.935
regulation of secretion GO:0051046 274 0.934
regulation of calcium ion transport GO:0051924 69 0.934
mesonephros development GO:0001823 97 0.934
muscle cell proliferation GO:0033002 52 0.934
Rat
response to corticosteroid GO:0031960 20 0.934
Rat
regulation of neuron apoptotic process GO:0043523 122 0.933
endocardial cushion formation GO:0003272 13 0.933
cation homeostasis GO:0055080 212 0.932
negative regulation of epithelial cell proliferation GO:0050680 64 0.931
kidney morphogenesis GO:0060993 83 0.928
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.928
peptide secretion GO:0002790 114 0.927
alpha amino acid metabolic process GO:1901605 59 0.927
Mouse
response to increased oxygen levels GO:0036296 2 0.927
Rat
cgmp biosynthetic process GO:0006182 13 0.924
regulation of leukocyte differentiation GO:1902105 159 0.924
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.924
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.921
dna metabolic process GO:0006259 303 0.920
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.919
regulation of organelle organization GO:0033043 289 0.919
Mouse
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.919
metal ion homeostasis GO:0055065 189 0.918
mammary gland branching involved in pregnancy GO:0060745 6 0.918
heart contraction GO:0060047 93 0.918
cellular ketone metabolic process GO:0042180 84 0.917
phosphatidylinositol mediated signaling GO:0048015 41 0.917
regulation of neuron death GO:1901214 134 0.916
inflammatory response GO:0006954 244 0.916
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.916
apoptotic signaling pathway GO:0097190 306 0.915
positive regulation of phosphoprotein phosphatase activity GO:0032516 1 0.915
cartilage development GO:0051216 140 0.915
response to organic cyclic compound GO:0014070 198 0.914
Rat
regulation of nucleotide metabolic process GO:0006140 169 0.914
peptide hormone secretion GO:0030072 109 0.914
purine containing compound metabolic process GO:0072521 311 0.910
cellular chemical homeostasis GO:0055082 215 0.910
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.910
calcium ion transport GO:0006816 159 0.909
muscle cell development GO:0055001 133 0.909
positive regulation of mitotic cell cycle embryonic GO:0045977 2 0.909
sphingolipid metabolic process GO:0006665 45 0.909
ureteric bud morphogenesis GO:0060675 62 0.908
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.908
smooth muscle cell migration GO:0014909 10 0.907
stem cell differentiation GO:0048863 268 0.907
cellular response to hormone stimulus GO:0032870 150 0.907
positive regulation of cell cycle GO:0045787 92 0.906
artery development GO:0060840 53 0.906
leukocyte differentiation GO:0002521 342 0.904
cellular response to extracellular stimulus GO:0031668 81 0.903
extrinsic apoptotic signaling pathway GO:0097191 126 0.903
spermatogenesis GO:0007283 284 0.902
placenta development GO:0001890 140 0.902
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.902
renal tubule morphogenesis GO:0061333 72 0.902
vegf activated neuropilin signaling pathway GO:0038190 2 0.901
positive regulation of protein modification process GO:0031401 299 0.901
Mouse
rho protein signal transduction GO:0007266 32 0.901
ventricular septum development GO:0003281 42 0.900
purine nucleoside metabolic process GO:0042278 241 0.900
positive regulation of cholesterol esterification GO:0010873 1 0.897
microglia differentiation GO:0014004 2 0.897
determination of heart left right asymmetry GO:0061371 48 0.897
intestinal cholesterol absorption GO:0030299 5 0.896
nucleocytoplasmic transport GO:0006913 139 0.894
regulation of neural precursor cell proliferation GO:2000177 70 0.894
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.889
hematopoietic progenitor cell differentiation GO:0002244 143 0.888
response to retinoic acid GO:0032526 56 0.888
organonitrogen compound biosynthetic process GO:1901566 192 0.888
regulation of blood vessel remodeling GO:0060312 3 0.887
positive regulation of lipid kinase activity GO:0090218 11 0.886
chemical homeostasis within a tissue GO:0048875 9 0.886
septum primum development GO:0003284 4 0.886
insulin receptor signaling pathway GO:0008286 49 0.884
cell migration involved in kidney development GO:0035787 3 0.884
g protein coupled receptor signaling pathway GO:0007186 243 0.884
Mouse
myeloid cell homeostasis GO:0002262 114 0.883
stem cell maintenance GO:0019827 130 0.883
renal system process involved in regulation of blood volume GO:0001977 4 0.882
positive regulation of fatty acid oxidation GO:0046321 4 0.881
response to thyroid hormone GO:0097066 2 0.877
positive regulation of dephosphorylation GO:0035306 6 0.877
positive regulation of insulin secretion GO:0032024 26 0.877
connective tissue development GO:0061448 179 0.877
branching involved in ureteric bud morphogenesis GO:0001658 56 0.876
coronary vein morphogenesis GO:0003169 2 0.874
cell migration involved in vasculogenesis GO:0035441 2 0.874
peptide transport GO:0015833 133 0.873
cell migration involved in endocardial cushion formation GO:0003273 3 0.870
positive regulation of cellular amine metabolic process GO:0033240 5 0.870
positive regulation of lymphangiogenesis GO:1901492 3 0.869
dna biosynthetic process GO:0071897 22 0.869
retina vasculature development in camera type eye GO:0061298 17 0.868
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.866
stem cell development GO:0048864 219 0.866
ameboidal type cell migration GO:0001667 128 0.864
positive regulation of leukocyte proliferation GO:0070665 73 0.864
cgmp metabolic process GO:0046068 20 0.862
regulation of vasoconstriction GO:0019229 14 0.861
regulation of cardiac muscle tissue development GO:0055024 31 0.860
regulation of embryonic development GO:0045995 71 0.860
myeloid leukocyte activation GO:0002274 83 0.859
regulation of protein serine threonine kinase activity GO:0071900 157 0.859
regulation of systemic arterial blood pressure GO:0003073 61 0.855
skeletal muscle organ development GO:0060538 163 0.855
cholesterol esterification GO:0034435 3 0.854
regulation of triglyceride metabolic process GO:0090207 17 0.854
germ cell development GO:0007281 185 0.850
cellular response to x ray GO:0071481 2 0.850
endochondral bone morphogenesis GO:0060350 50 0.849
regulation of cell shape GO:0008360 39 0.847
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902239 1 0.847
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902218 1 0.845
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.845
positive regulation of programmed cell death GO:0043068 218 0.844
Rat
response to acid chemical GO:0001101 111 0.844
Rat
cardiac myofibril assembly GO:0055003 12 0.844
regulation of apoptotic signaling pathway GO:2001233 197 0.843
regulation of transmembrane transport GO:0034762 128 0.843
catecholamine metabolic process GO:0006584 30 0.840
negative regulation of nervous system development GO:0051961 156 0.839
morphogenesis of a branching structure GO:0001763 203 0.839
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.838
odontogenesis of dentin containing tooth GO:0042475 66 0.837
smooth muscle contraction GO:0006939 44 0.837
embryonic organ morphogenesis GO:0048562 276 0.837
cholesterol storage GO:0010878 4 0.835
appendage morphogenesis GO:0035107 149 0.833
positive regulation of mesonephros development GO:0061213 20 0.833
digestion GO:0007586 40 0.828
negative regulation of protein metabolic process GO:0051248 282 0.828
Mouse
cell differentiation involved in kidney development GO:0061005 33 0.827
regulation of angiogenesis GO:0045765 81 0.826
eye photoreceptor cell differentiation GO:0001754 41 0.826
embryonic placenta development GO:0001892 98 0.825
regulation of stem cell proliferation GO:0072091 78 0.825
positive regulation of hormone secretion GO:0046887 38 0.825
negative regulation of epithelial cell migration GO:0010633 9 0.824
steroid metabolic process GO:0008202 119 0.824
negative regulation of endothelial cell proliferation GO:0001937 8 0.824
purine containing compound biosynthetic process GO:0072522 70 0.822
metanephros development GO:0001656 79 0.822
regulation of neurotrophin trk receptor signaling pathway GO:0051386 4 0.821
fat cell differentiation GO:0045444 160 0.820
wnt signaling pathway involved in kidney development GO:0061289 2 0.819
cellular metal ion homeostasis GO:0006875 151 0.817
atrial septum primum morphogenesis GO:0003289 3 0.817
aorta morphogenesis GO:0035909 22 0.817
sensory organ morphogenesis GO:0090596 242 0.815
positive regulation of neuron differentiation GO:0045666 141 0.814
peptidyl serine phosphorylation GO:0018105 74 0.813
metanephric tubule development GO:0072170 18 0.812
positive regulation of nitric oxide synthase activity GO:0051000 2 0.811
positive regulation of protein transport GO:0051222 93 0.810
metanephric glomerular epithelium development GO:0072244 3 0.810
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.809
cyclic purine nucleotide metabolic process GO:0052652 43 0.809
regulation of homeostatic process GO:0032844 182 0.808
response to monosaccharide GO:0034284 67 0.807
Rat
melanocyte adhesion GO:0097326 1 0.806
cellular homeostasis GO:0019725 240 0.806
regulation of peptidase activity GO:0052547 96 0.804
positive regulation of protein phosphorylation GO:0001934 242 0.803
respiratory tube development GO:0030323 167 0.802
regulation of myeloid cell differentiation GO:0045637 96 0.802
apoptotic process involved in mammary gland involution GO:0060057 4 0.802
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.801
regulation of glomerular filtration GO:0003093 3 0.801
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.800
collagen metabolic process GO:0032963 17 0.800
male sex differentiation GO:0046661 109 0.799
regulation of the force of heart contraction by chemical signal GO:0003057 5 0.798
neuropilin signaling pathway GO:0038189 2 0.798
regulation of intestinal cholesterol absorption GO:0030300 4 0.797
regulation of cellular component biogenesis GO:0044087 181 0.797
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.797
metanephric glomerulus vasculature development GO:0072239 7 0.794
phospholipase c activating angiotensin activated signaling pathway GO:0086097 1 0.794
cellular response to external stimulus GO:0071496 88 0.792
Rat
heart valve development GO:0003170 23 0.792
face development GO:0060324 38 0.792
drug catabolic process GO:0042737 2 0.790
Mouse
phosphatidylinositol metabolic process GO:0046488 45 0.789
digestive system development GO:0055123 200 0.788
regulation of ion transport GO:0043269 215 0.788
regulation of androgen receptor signaling pathway GO:0060765 3 0.787
cellular response to amino acid stimulus GO:0071230 29 0.786
face morphogenesis GO:0060325 29 0.785
insulin secretion GO:0030073 89 0.785
digestive tract morphogenesis GO:0048546 147 0.783
negative regulation of hormone secretion GO:0046888 20 0.781
positive regulation of cgmp biosynthetic process GO:0030828 6 0.781
regulation of wound healing GO:0061041 40 0.781
second messenger mediated signaling GO:0019932 73 0.780
mast cell differentiation GO:0060374 5 0.780
cellular response to peptide hormone stimulus GO:0071375 92 0.780
ventricular cardiac muscle cell action potential GO:0086005 4 0.779
cell growth involved in cardiac muscle cell development GO:0061049 3 0.776
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.775
glomerular endothelium development GO:0072011 2 0.774
t cell activation GO:0042110 289 0.774
regulation of myeloid dendritic cell activation GO:0030885 5 0.772
positive regulation of angiogenesis GO:0045766 46 0.772
regulation of kinase activity GO:0043549 249 0.772
ossification GO:0001503 216 0.771
negative regulation of cell development GO:0010721 169 0.771
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.770
regulation of axon extension GO:0030516 43 0.769
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 0.769
antral ovarian follicle growth GO:0001547 5 0.768
cell fate commitment GO:0045165 210 0.764
pro b cell differentiation GO:0002328 10 0.763
protein o linked glycosylation GO:0006493 16 0.763
response to iron ion GO:0010039 4 0.762
pigment cell differentiation GO:0050931 27 0.760
positive regulation of nervous system development GO:0051962 221 0.758
regulation of secretion by cell GO:1903530 249 0.757
negative regulation of endothelial cell migration GO:0010596 4 0.756
regulation of cgmp metabolic process GO:0030823 12 0.755
mesangial cell differentiation GO:0072007 4 0.754
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.753
cellular calcium ion homeostasis GO:0006874 119 0.752
nephron morphogenesis GO:0072028 69 0.752
regulation of branching involved in salivary gland morphogenesis by epithelial mesenchymal signaling GO:0060683 1 0.752
activation of janus kinase activity GO:0042976 2 0.751
positive regulation of secretion GO:0051047 130 0.749
metanephric glomerulus morphogenesis GO:0072275 3 0.748
nucleoside phosphate metabolic process GO:0006753 338 0.748
response to vitamin d GO:0033280 3 0.747
ventricular septum morphogenesis GO:0060412 27 0.745
positive regulation of hydrolase activity GO:0051345 148 0.745
metanephric nephron morphogenesis GO:0072273 19 0.744
maternal placenta development GO:0001893 20 0.743
metanephric nephron epithelium development GO:0072243 19 0.742
male gonad development GO:0008584 88 0.741
glycosyl compound metabolic process GO:1901657 246 0.740
cholesterol transport GO:0030301 38 0.739
positive regulation of phosphatase activity GO:0010922 4 0.739
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.738
Mouse
cellular response to thyroid hormone stimulus GO:0097067 1 0.735
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.732
negative regulation of cartilage development GO:0061037 17 0.732
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger GO:0007199 1 0.731
positive regulation of leukocyte differentiation GO:1902107 86 0.729
kidney vasculature development GO:0061440 15 0.728
positive regulation of myeloid cell differentiation GO:0045639 43 0.728
epithelial cell differentiation involved in kidney development GO:0035850 23 0.727
endothelial cell migration GO:0043542 44 0.727
cellular response to oxygen levels GO:0071453 20 0.727
endocardial cell differentiation GO:0060956 4 0.726
positive regulation of fibroblast proliferation GO:0048146 20 0.724
striated muscle contraction GO:0006941 45 0.723
Mouse
axon extension involved in axon guidance GO:0048846 14 0.721
mitral valve morphogenesis GO:0003183 4 0.721
mesenchymal cell proliferation GO:0010463 44 0.721
macrophage differentiation GO:0030225 20 0.720
outflow tract morphogenesis GO:0003151 53 0.720
cellular divalent inorganic cation homeostasis GO:0072503 127 0.718
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.718
female gonad development GO:0008585 71 0.717
regulation of cellular response to growth factor stimulus GO:0090287 82 0.715
positive regulation of behavior GO:0048520 40 0.714
metanephric epithelium development GO:0072207 21 0.714
fused antrum stage GO:0048165 1 0.712
regulation of protein localization GO:0032880 231 0.711
wound healing GO:0042060 157 0.711
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.710
positive regulation of ossification GO:0045778 47 0.710
positive regulation of lipid metabolic process GO:0045834 40 0.709
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.709
cardiac septum development GO:0003279 59 0.709
regulation of nucleoside metabolic process GO:0009118 130 0.708
positive regulation of apoptotic process GO:0043065 217 0.706
Rat
cardiac chamber development GO:0003205 108 0.706
regulation of carbohydrate metabolic process GO:0006109 75 0.704
ribonucleotide biosynthetic process GO:0009260 59 0.704
limb development GO:0060173 166 0.704
cellular response to organonitrogen compound GO:0071417 145 0.703
Rat
epithelial cell development GO:0002064 159 0.703
growth plate cartilage development GO:0003417 14 0.702
regulation of cell adhesion GO:0030155 154 0.702
neural crest cell migration GO:0001755 32 0.701
regulation of response to wounding GO:1903034 189 0.700
chondrocyte hypertrophy GO:0003415 4 0.699
regulation of lymphangiogenesis GO:1901490 3 0.698
male gamete generation GO:0048232 285 0.695
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.695
t cell differentiation GO:0030217 174 0.695
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.695
regulation of fat cell differentiation GO:0045598 81 0.694

Nos3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.833
disease of anatomical entity DOID:7 0 0.711
vascular disease DOID:178 0 0.711
cardiovascular system disease DOID:1287 0 0.711