|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.663
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.516
|
Mouse Fly |
|
|
cytokine production
|
GO:0001816 |
319 |
0.488
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.376
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.365
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.355
|
Mouse Fly |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.330
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.330
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.310
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.307
|
Mouse Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.296
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.282
|
Mouse |
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.262
|
Fly |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.258
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.233
|
Mouse |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.218
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.215
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.214
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.211
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.205
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.200
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.200
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.197
|
Mouse |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.194
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.190
|
Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.189
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.184
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.177
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.177
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.175
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.171
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.161
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.158
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.157
|
Mouse Fly |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.154
|
Mouse |
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.152
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.150
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.149
|
Mouse |
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.147
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.147
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.145
|
Mouse |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.144
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.144
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.144
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.144
|
Fly |
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.141
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.141
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.136
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.129
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.127
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.125
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.125
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.122
|
Mouse |
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.121
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.121
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.118
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.116
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.116
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.114
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.114
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.114
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.107
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.105
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.104
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.104
|
Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.103
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.103
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.102
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.101
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.101
|
Mouse |
|
|
germinal center formation
|
GO:0002467 |
16 |
0.100
|
Mouse |
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.099
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.099
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.098
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.098
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.097
|
Mouse |
|
|
type i interferon production
|
GO:0032606 |
29 |
0.097
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.096
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.095
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.094
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.093
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.093
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.093
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.091
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.089
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.088
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.087
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.086
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.085
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.084
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.083
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.082
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.082
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.081
|
Mouse |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.079
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.078
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.078
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.077
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.077
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.075
|
Fly |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.073
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.073
|
Mouse |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.073
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.073
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.073
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.073
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.071
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.070
|
Mouse |
|
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
0.070
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.070
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.070
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.069
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.069
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.068
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.066
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.066
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.064
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.063
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.063
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.063
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.062
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.062
|
Mouse |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.061
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.061
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.061
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.061
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.061
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.060
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.060
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.059
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.059
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.059
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.059
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.058
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.058
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.058
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.058
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.058
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.057
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.057
|
Mouse |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.057
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.056
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.056
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.056
|
|
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
0.056
|
Mouse |
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.056
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.056
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.055
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.055
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.054
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.054
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.054
|
Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.053
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.053
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.052
|
Mouse |
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.052
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.052
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.051
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.051
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.051
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.051
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.051
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.050
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.050
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.049
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.049
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.049
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.048
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.048
|
Mouse |
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.048
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.048
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.048
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.047
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.047
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.047
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.047
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.047
|
|
|
|
regulation of defense response to fungus
|
GO:1900150 |
1 |
0.046
|
Fly |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.046
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.046
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.046
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
14 |
0.046
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.045
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.045
|
Fly |
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.045
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.045
|
Mouse |
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.045
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.044
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.044
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.044
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.043
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.043
|
Mouse |
|
|
interferon beta production
|
GO:0032608 |
16 |
0.043
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.043
|
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.043
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.043
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.043
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.042
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.042
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.042
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.042
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.042
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.042
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.042
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.041
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.041
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.041
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.040
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.040
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.040
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.040
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.040
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.040
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.040
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.039
|
Mouse |
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.038
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.038
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.038
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.038
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.037
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.037
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.037
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.037
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.037
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.037
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.037
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.037
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.037
|
Mouse |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.037
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.037
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.037
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.037
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.036
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.036
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.036
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.036
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.036
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.035
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.035
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.035
|
Mouse |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.035
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.035
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.035
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.035
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.034
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.034
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.034
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.034
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.034
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.033
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.033
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.033
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.033
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.033
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.033
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.033
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.033
|
Mouse |
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.033
|
Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.032
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.032
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.032
|
Fly |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.032
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.032
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.032
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.032
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.031
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.031
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.031
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.031
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.030
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.030
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.030
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.030
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.030
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.030
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.030
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.030
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.030
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.030
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.030
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.030
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.029
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.029
|
|
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
15 |
0.029
|
Fly |
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.029
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.029
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.029
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.029
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.029
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.029
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.029
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.029
|
Fly |
|
|
cell killing
|
GO:0001906 |
67 |
0.029
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.028
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.028
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.028
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.028
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.028
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.028
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.028
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.028
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.028
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.028
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.028
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.027
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.027
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.027
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.027
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.027
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.027
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.027
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.027
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.027
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.027
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.027
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.027
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.026
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.026
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.026
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.026
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.026
|
Fly |
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.026
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.026
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.026
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.025
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.025
|
|
|
|
positive regulation of neutrophil mediated killing of symbiont cell
|
GO:0070961 |
1 |
0.025
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.025
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.025
|
Fly |
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.025
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.025
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.025
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.025
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.025
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.025
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.025
|
|
|
|
regulation of interleukin 10 biosynthetic process
|
GO:0045074 |
1 |
0.024
|
Mouse |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.024
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.024
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.024
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.024
|
Mouse |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.024
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.024
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.024
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.024
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.024
|
Fly |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.024
|
Fly |
|
|
placenta development
|
GO:0001890 |
140 |
0.024
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.023
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.023
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.023
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.023
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.023
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.023
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.023
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.023
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.023
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.023
|
Fly |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.023
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.023
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.023
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.023
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.023
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.023
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.023
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.022
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.022
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.022
|
|
|
|
superoxide anion generation
|
GO:0042554 |
11 |
0.022
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.022
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.022
|
|
|
|
positive regulation of interleukin 10 biosynthetic process
|
GO:0045082 |
1 |
0.022
|
Mouse |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.022
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.022
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.022
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.021
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.021
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.021
|
Mouse |
|
|
lipid localization
|
GO:0010876 |
126 |
0.021
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.021
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.021
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.021
|
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.021
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.020
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.020
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.020
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.020
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.020
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.020
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.020
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.020
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.020
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
5 |
0.020
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.020
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.020
|
Mouse |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.020
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.020
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.020
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.020
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.020
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.020
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.020
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.020
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.020
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.020
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.020
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.020
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.020
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.020
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.020
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.019
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.019
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.019
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.019
|
Mouse |
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.019
|
Mouse |
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.019
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.019
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.019
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.019
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.019
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.019
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.019
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.019
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.019
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.019
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.019
|
Mouse |
|
|
muscle system process
|
GO:0003012 |
141 |
0.019
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.019
|
Mouse |
|
|
anion transport
|
GO:0006820 |
177 |
0.019
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.019
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.018
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.018
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.018
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.018
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.018
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.018
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.018
|
Mouse |
|
|
positive regulation of t cell mediated immunity
|
GO:0002711 |
24 |
0.018
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.018
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.018
|
Mouse Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.018
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.018
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.018
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.018
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.018
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.018
|
Mouse |
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.018
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.018
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.018
|
Mouse |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.018
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.018
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.017
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.017
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.017
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.017
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.017
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.017
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.017
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.017
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.017
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.017
|
Fly |
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.017
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.017
|
Mouse |
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.017
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.017
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.017
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.017
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.017
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.017
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.017
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.017
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.017
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.016
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.016
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.016
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.016
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.016
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.016
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.016
|
|
|
|
regulation of type i interferon production
|
GO:0032479 |
22 |
0.016
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.016
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.016
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.016
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.016
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.016
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.016
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.016
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.016
|
Fly |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.016
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.016
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.016
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.016
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.016
|
Fly |
