|
|
germinal center formation
|
GO:0002467 |
16 |
0.820
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.812
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.808
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.789
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.728
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.702
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.667
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.638
|
|
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
0.604
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.601
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.599
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.574
|
|
|
|
regulation of defense response to fungus
|
GO:1900150 |
1 |
0.563
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.560
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.552
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.550
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.541
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.537
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.522
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.519
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.506
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.506
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.504
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.488
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.480
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.471
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.469
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.469
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.406
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.378
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.374
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.364
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.357
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.348
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.343
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.338
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.338
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.337
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.323
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.322
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.319
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.312
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.310
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.303
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.301
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.300
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.287
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.281
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.262
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.262
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.256
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.252
|
|
|
|
follicular dendritic cell differentiation
|
GO:0002268 |
2 |
0.251
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.250
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.243
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.239
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.239
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.232
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.231
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.228
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.227
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.224
|
|
|
|
positive regulation of interleukin 10 biosynthetic process
|
GO:0045082 |
1 |
0.222
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.221
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.220
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.217
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.210
|
|
|
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
0.208
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.207
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.205
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.201
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.200
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.197
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.195
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.193
|
|
|
|
regulation of hepatocyte proliferation
|
GO:2000345 |
6 |
0.190
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.190
|
Human |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.188
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.188
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.187
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.185
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.183
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.179
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.178
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.177
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.176
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.174
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.173
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.168
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.167
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.165
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.160
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.159
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.158
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.158
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.157
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.156
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.151
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.149
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.148
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.147
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.147
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.146
|
|
|
|
follicular dendritic cell activation
|
GO:0002266 |
2 |
0.146
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.146
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.140
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.140
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.139
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.138
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.137
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.136
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.135
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.134
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.133
|
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.126
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.125
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.124
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.124
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.123
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.122
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.121
|
|
|
|
regulation of interleukin 10 biosynthetic process
|
GO:0045074 |
1 |
0.119
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.119
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.119
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.119
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.118
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.117
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.116
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.116
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.115
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.115
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.114
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.113
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.113
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.113
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.113
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.111
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.111
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.110
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.108
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.108
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.107
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.106
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.106
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.104
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.104
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.103
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.103
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.101
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.100
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.100
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.098
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.097
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.097
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.097
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.097
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.097
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.093
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.092
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.092
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.092
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.091
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.091
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.091
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.090
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.089
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.088
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.088
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.087
|
|
|
|
negative regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031665 |
3 |
0.087
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.087
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.086
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.085
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.085
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.085
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.084
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.083
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.082
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.082
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.081
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.080
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.080
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.080
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.079
|
|
|
|
interleukin 10 biosynthetic process
|
GO:0042091 |
1 |
0.079
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.079
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.077
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.076
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.076
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.076
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.075
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.075
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.074
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.071
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.071
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.070
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.070
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.070
|
Human |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.070
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.069
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.069
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.069
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.068
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.068
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.067
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.067
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.066
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.066
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.066
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.066
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.065
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.065
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.065
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.064
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.064
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.064
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.064
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.064
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.064
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.063
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.063
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.062
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.062
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.062
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.062
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.062
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.062
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.062
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.062
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.061
|
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.061
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.061
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.060
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.060
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.059
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.059
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.059
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.058
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.058
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.058
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.058
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.057
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.057
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.057
|
Human |
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.057
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.056
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.056
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.056
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.055
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.055
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.054
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.054
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.054
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.054
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.054
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.054
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.053
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.053
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.052
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.052
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.052
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.052
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.052
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.052
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.052
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
32 |
0.052
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.051
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.051
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.051
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.051
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.051
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.051
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.050
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.050
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.050
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.049
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.049
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.049
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.048
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.048
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.048
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.047
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.047
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.047
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.046
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.046
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.046
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.046
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.046
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.046
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.045
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.045
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.045
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.044
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.044
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.044
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.043
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.043
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.043
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.043
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.043
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.042
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.042
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.042
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.042
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.041
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.041
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:0097296 |
2 |
0.041
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.041
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.041
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.041
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.041
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.041
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.041
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.041
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.041
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.041
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.040
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.040
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
7 |
0.040
|
|
|
|
positive regulation of growth hormone receptor signaling pathway
|
GO:0060399 |
3 |
0.040
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.040
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.040
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.039
|
Human |
|
|
regionalization
|
GO:0003002 |
337 |
0.039
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.039
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.039
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.039
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.039
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.039
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.038
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.038
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class i
|
GO:0002474 |
9 |
0.038
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.038
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.038
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.038
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.038
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.038
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.037
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.037
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.037
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.037
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.037
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.037
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.037
|
Human |
|
|
dendrite development
|
GO:0016358 |
115 |
0.036
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.036
|
|
|
|
apoptotic process involved in embryonic digit morphogenesis
|
GO:1902263 |
3 |
0.036
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.035
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.035
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.035
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.035
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.034
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.034
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.034
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.034
|
|
|
|
defense response to fungus
|
GO:0050832 |
12 |
0.034
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.034
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.033
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.033
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.033
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.033
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.033
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.033
|
|
|
|
regulation of killing of cells of other organism
|
GO:0051709 |
4 |
0.033
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.033
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.033
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.033
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.032
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.032
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.032
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.032
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.032
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.032
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.032
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.032
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.032
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.032
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.032
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.031
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.031
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.031
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.031
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.031
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.030
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.030
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.030
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.030
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.030
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
17 |
0.030
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.030
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
11 |
0.030
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.030
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.030
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.030
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.029
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.029
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.029
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.029
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.029
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.029
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.029
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.029
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
12 |
0.029
|
|
|
|
positive regulation of protein homooligomerization
|
GO:0032464 |
3 |
0.029
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.028
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.028
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.028
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
4 |
0.028
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.028
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.028
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.028
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.028
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.028
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.028
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.028
|
|
|
|
negative regulation of cell adhesion involved in substrate bound cell migration
|
GO:0006933 |
3 |
0.027
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.027
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.027
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.027
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.027
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.027
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.027
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.027
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.027
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.027
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.027
|
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
6 |
0.027
|
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
10 |
0.027
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.027
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.027
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.026
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.026
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.026
|
|
|
|
positive regulation of t cell mediated immunity
|
GO:0002711 |
24 |
0.026
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.026
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.026
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.026
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.026
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.026
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.026
|
|
|
|
response to heat
|
GO:0009408 |
27 |
0.026
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.026
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.026
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.026
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.026
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.026
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.025
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.025
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.025
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.025
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.025
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.025
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.025
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.025
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.025
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.025
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
4 |
0.025
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.025
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.025
|
|
|
|
negative regulation of interleukin 10 production
|
GO:0032693 |
8 |
0.025
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.024
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.024
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.024
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.024
|
|
|
|
response to exogenous dsrna
|
GO:0043330 |
22 |
0.024
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.024
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.024
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
9 |
0.024
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.024
|
|
|
|
negative regulation of hypersensitivity
|
GO:0002884 |
3 |
0.024
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.024
|
|