Mus musculus

0 known processes

Iars2

isoleucine-tRNA synthetase 2, mitochondrial

(Aliases: MGC63429,2010002H18Rik,C79125)

Iars2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
coenzyme metabolic process GO:0006732 52 0.181
oxidation reduction process GO:0055114 342 0.180
cellular lipid metabolic process GO:0044255 323 0.150
coenzyme biosynthetic process GO:0009108 23 0.141
nucleobase containing small molecule metabolic process GO:0055086 352 0.111
cellular ketone metabolic process GO:0042180 84 0.110
sulfur compound metabolic process GO:0006790 100 0.106
fatty acid metabolic process GO:0006631 121 0.104
monocarboxylic acid metabolic process GO:0032787 191 0.102
aromatic compound catabolic process GO:0019439 286 0.098
purine nucleotide metabolic process GO:0006163 302 0.096
purine ribonucleotide metabolic process GO:0009150 290 0.093
heterocycle catabolic process GO:0046700 280 0.089
purine nucleoside metabolic process GO:0042278 241 0.077
purine containing compound metabolic process GO:0072521 311 0.071
glycosyl compound metabolic process GO:1901657 246 0.068
purine nucleoside triphosphate metabolic process GO:0009144 226 0.064
mitochondrion organization GO:0007005 134 0.063
nucleoside phosphate metabolic process GO:0006753 338 0.059
cellular nitrogen compound catabolic process GO:0044270 280 0.059
intracellular protein transport GO:0006886 204 0.058
nucleotide metabolic process GO:0009117 332 0.058
ribonucleotide metabolic process GO:0009259 291 0.058
nucleoside metabolic process GO:0009116 246 0.057
regulation of cellular ketone metabolic process GO:0010565 66 0.056
nucleoside triphosphate metabolic process GO:0009141 230 0.055
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.055
organic cyclic compound catabolic process GO:1901361 295 0.055
acyl coa metabolic process GO:0006637 19 0.054
thioester metabolic process GO:0035383 19 0.053
cellular amino acid metabolic process GO:0006520 103 0.053
apoptotic signaling pathway GO:0097190 306 0.053
ribose phosphate metabolic process GO:0019693 291 0.053
membrane organization GO:0061024 245 0.052
purine ribonucleoside metabolic process GO:0046128 241 0.047
ribonucleoside triphosphate metabolic process GO:0009199 220 0.046
action potential GO:0001508 78 0.042
cofactor metabolic process GO:0051186 80 0.040
ribonucleoside metabolic process GO:0009119 245 0.040
carbohydrate derivative catabolic process GO:1901136 231 0.039
cellular amine metabolic process GO:0044106 44 0.039
intrinsic apoptotic signaling pathway GO:0097193 132 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
transmission of nerve impulse GO:0019226 76 0.038
fatty acid oxidation GO:0019395 28 0.037
energy derivation by oxidation of organic compounds GO:0015980 77 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
amine metabolic process GO:0009308 45 0.036
regulation of cellular catabolic process GO:0031329 242 0.036
regulation of cellular amine metabolic process GO:0033238 20 0.035
response to oxidative stress GO:0006979 123 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
organophosphate catabolic process GO:0046434 232 0.034
acetyl coa biosynthetic process GO:0006085 5 0.033
lipid biosynthetic process GO:0008610 179 0.033
regulation of hydrolase activity GO:0051336 246 0.033
purine nucleotide catabolic process GO:0006195 211 0.032
organic acid catabolic process GO:0016054 51 0.031
small molecule biosynthetic process GO:0044283 132 0.031
thioester biosynthetic process GO:0035384 7 0.031
cofactor biosynthetic process GO:0051188 41 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
cellular macromolecule catabolic process GO:0044265 206 0.028
acyl coa biosynthetic process GO:0071616 7 0.028
multicellular organismal signaling GO:0035637 91 0.028
nucleotide catabolic process GO:0009166 217 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
macromolecule catabolic process GO:0009057 281 0.027
response to organonitrogen compound GO:0010243 246 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
neuronal action potential GO:0019228 54 0.027
positive regulation of protein modification process GO:0031401 299 0.026
regulation of membrane potential GO:0042391 192 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.025
anatomical structure homeostasis GO:0060249 145 0.025
lipid oxidation GO:0034440 29 0.025
cell type specific apoptotic process GO:0097285 268 0.025
alcohol metabolic process GO:0006066 116 0.025
translation GO:0006412 93 0.024
nucleoside catabolic process GO:0009164 206 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
ras protein signal transduction GO:0007265 77 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.023
generation of precursor metabolites and energy GO:0006091 103 0.022
cellular lipid catabolic process GO:0044242 52 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
maintenance of location GO:0051235 89 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
mitochondrial translation GO:0032543 4 0.022
dna metabolic process GO:0006259 303 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.021
lipid localization GO:0010876 126 0.021
organelle localization GO:0051640 179 0.021
homeostasis of number of cells GO:0048872 210 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
purine containing compound catabolic process GO:0072523 213 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
lipid modification GO:0030258 65 0.021
morphogenesis of embryonic epithelium GO:0016331 159 0.021
regulation of secretion by cell GO:1903530 249 0.021
protein processing GO:0016485 163 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
cytokine production GO:0001816 319 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
small molecule catabolic process GO:0044282 71 0.020
phospholipid metabolic process GO:0006644 87 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of organelle organization GO:0033043 289 0.019
nuclear transport GO:0051169 139 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
guanosine containing compound metabolic process GO:1901068 144 0.019
protein localization to organelle GO:0033365 185 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.018
ensheathment of neurons GO:0007272 76 0.018
monocarboxylic acid catabolic process GO:0072329 27 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
carboxylic acid catabolic process GO:0046395 51 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
regulation of cell activation GO:0050865 289 0.018
atp metabolic process GO:0046034 75 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
gtp metabolic process GO:0046039 144 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
transmembrane transport GO:0055085 412 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
sulfur compound biosynthetic process GO:0044272 37 0.017
ion transmembrane transport GO:0034220 361 0.017
neural tube formation GO:0001841 108 0.017
carbohydrate metabolic process GO:0005975 230 0.017
synapse organization GO:0050808 125 0.016
gtp catabolic process GO:0006184 143 0.016
lipid catabolic process GO:0016042 69 0.016
cytoplasmic transport GO:0016482 234 0.016
positive regulation of cell activation GO:0050867 158 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
positive regulation of organelle organization GO:0010638 128 0.016
rho protein signal transduction GO:0007266 32 0.016
forebrain development GO:0030900 302 0.016
regulation of kinase activity GO:0043549 249 0.016
immune effector process GO:0002252 321 0.016
blood circulation GO:0008015 195 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
glycerol ether metabolic process GO:0006662 2 0.016
negative regulation of immune system process GO:0002683 209 0.016
response to organic cyclic compound GO:0014070 198 0.015
regulation of protein transport GO:0051223 163 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
regulation of cytokine production GO:0001817 266 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
myelination GO:0042552 74 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
tube formation GO:0035148 140 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
interleukin 8 production GO:0032637 4 0.014
regulation of mitochondrion organization GO:0010821 27 0.014
cellular respiration GO:0045333 38 0.014
cation transmembrane transport GO:0098655 266 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
protein maturation GO:0051604 176 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
endomembrane system organization GO:0010256 147 0.014
leukocyte differentiation GO:0002521 342 0.014
protein targeting GO:0006605 143 0.014
protein oligomerization GO:0051259 67 0.014
lateral inhibition GO:0046331 1 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
regulation of secretion GO:0051046 274 0.014
protein secretion GO:0009306 111 0.014
response to growth factor GO:0070848 198 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
axon ensheathment GO:0008366 76 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
mitotic cell cycle GO:0000278 195 0.014
cation transport GO:0006812 399 0.014
fatty acid catabolic process GO:0009062 25 0.014
ossification GO:0001503 216 0.014
protein localization to nucleus GO:0034504 121 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
multicellular organism growth GO:0035264 161 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
adult behavior GO:0030534 135 0.013
negative regulation of molecular function GO:0044092 258 0.013
cristae formation GO:0042407 3 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
mitochondrion transport along microtubule GO:0047497 3 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
peptidyl amino acid modification GO:0018193 336 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
cell adhesion GO:0007155 329 0.013
protein import GO:0017038 101 0.013
peptidyl serine modification GO:0018209 83 0.013
mitochondrion morphogenesis GO:0070584 13 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
response to endoplasmic reticulum stress GO:0034976 53 0.013
regulation of cell migration GO:0030334 219 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
negative regulation of dna replication GO:0008156 4 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
protein localization to membrane GO:0072657 108 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
neutral lipid metabolic process GO:0006638 57 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
digestive tract development GO:0048565 190 0.012
urogenital system development GO:0001655 261 0.012
cellular amide metabolic process GO:0043603 58 0.012
tube closure GO:0060606 91 0.012
cofactor transport GO:0051181 4 0.012
fatty acid beta oxidation GO:0006635 16 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
cellular homeostasis GO:0019725 240 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
camera type eye development GO:0043010 266 0.012
microtubule based process GO:0007017 236 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
mitochondrial fusion GO:0008053 9 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
positive regulation of growth GO:0045927 104 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
anion transport GO:0006820 177 0.012
neuron apoptotic process GO:0051402 142 0.012
renal system development GO:0072001 225 0.011
response to peptide hormone GO:0043434 127 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
cellular response to oxidative stress GO:0034599 76 0.011
macromolecule methylation GO:0043414 120 0.011
gland development GO:0048732 330 0.011
regulation of ion transport GO:0043269 215 0.011
neural tube development GO:0021915 160 0.011
t cell apoptotic process GO:0070231 39 0.011
spermatogenesis GO:0007283 284 0.011
methylation GO:0032259 134 0.011
ribose phosphate biosynthetic process GO:0046390 59 0.011
nitrogen compound transport GO:0071705 271 0.011
circulatory system process GO:0003013 197 0.011
response to insulin GO:0032868 100 0.011
regulation of cell motility GO:2000145 236 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of homeostatic process GO:0032844 182 0.011
endocytosis GO:0006897 168 0.011
stem cell differentiation GO:0048863 268 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
monosaccharide metabolic process GO:0005996 106 0.011
epithelial tube formation GO:0072175 130 0.011
digestive system development GO:0055123 200 0.011
epithelial cell proliferation GO:0050673 174 0.011
regulation of cell cycle GO:0051726 281 0.011
positive regulation of cell development GO:0010720 237 0.011
negative regulation of granulocyte differentiation GO:0030853 3 0.010
membrane fusion GO:0061025 38 0.010
cellular response to peptide GO:1901653 92 0.010
neuron migration GO:0001764 122 0.010
purine ribonucleotide biosynthetic process GO:0009152 59 0.010
regulation of defense response GO:0031347 233 0.010
regulation of transferase activity GO:0051338 263 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
innate immune response GO:0045087 157 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
cation homeostasis GO:0055080 212 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
defense response to other organism GO:0098542 197 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
dna integrity checkpoint GO:0031570 28 0.010
peptidyl serine phosphorylation GO:0018105 74 0.010
telencephalon development GO:0021537 186 0.010
regulation of protein secretion GO:0050708 82 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
neuron death GO:0070997 154 0.010
positive regulation of kinase activity GO:0033674 155 0.010

Iars2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.045
inherited metabolic disorder DOID:655 0 0.031
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.013
amino acid metabolic disorder DOID:9252 0 0.011
carbohydrate metabolic disorder DOID:2978 0 0.010
eye disease DOID:5614 0 0.010
eye and adnexa disease DOID:1492 0 0.010
sensory system disease DOID:0050155 0 0.010