Mus musculus

73 known processes

Arl6

ADP-ribosylation factor-like 6

(Aliases: BBS3,2210411E14Rik,1110018H24Rik)

Arl6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intraciliary retrograde transport GO:0035721 3 1.000
cilium morphogenesis GO:0060271 102 0.999
intraciliary transport GO:0042073 9 0.999
nonmotile primary cilium assembly GO:0035058 8 0.990
cilium assembly GO:0042384 81 0.984
microtubule based movement GO:0007018 84 0.957
cytoskeleton dependent intracellular transport GO:0030705 50 0.937
microtubule based transport GO:0010970 50 0.931
photoreceptor cell morphogenesis GO:0008594 3 0.923
cellular component assembly involved in morphogenesis GO:0010927 139 0.880
regulation of cilium movement GO:0003352 6 0.764
establishment of melanosome localization GO:0032401 11 0.697
Zebrafish
photoreceptor cell development GO:0042461 40 0.655
photoreceptor cell differentiation GO:0046530 52 0.643
regulation of cilium beat frequency involved in ciliary motility GO:0060296 5 0.633
organelle assembly GO:0070925 177 0.632
melanosome localization GO:0032400 12 0.623
Zebrafish
regulation of cilium movement involved in cell motility GO:0060295 5 0.576
eye photoreceptor cell differentiation GO:0001754 41 0.564
cilium movement involved in cell motility GO:0060294 5 0.561
cilium movement GO:0003341 28 0.558
cilium or flagellum dependent cell motility GO:0001539 6 0.535
regulation of cilium assembly GO:1902017 7 0.497
cilium dependent cell motility GO:0060285 6 0.430
regulation of cilium dependent cell motility GO:1902019 5 0.416
telencephalon development GO:0021537 186 0.399
regulation of microtubule based movement GO:0060632 8 0.391
axoneme assembly GO:0035082 15 0.348
microtubule based process GO:0007017 236 0.347
cellular response to leptin stimulus GO:0044320 6 0.343
fat cell differentiation GO:0045444 160 0.319
ventricular system development GO:0021591 27 0.297
sensory perception of smell GO:0007608 26 0.282
forebrain development GO:0030900 302 0.237
sensory perception of chemical stimulus GO:0007606 51 0.206
brain morphogenesis GO:0048854 32 0.194
cartilage development GO:0051216 140 0.185
microtubule cytoskeleton organization GO:0000226 157 0.185
striatum development GO:0021756 14 0.184
male gamete generation GO:0048232 285 0.168
skeletal system development GO:0001501 356 0.161
regionalization GO:0003002 337 0.146
establishment of anatomical structure orientation GO:0048560 1 0.136
establishment of vesicle localization GO:0051650 81 0.134
Zebrafish
olfactory learning GO:0008355 2 0.134
regulation of microtubule based process GO:0032886 52 0.129
cerebral cortex development GO:0021987 86 0.118
regulation of hormone levels GO:0010817 211 0.115
sensory organ morphogenesis GO:0090596 242 0.108
retina homeostasis GO:0001895 23 0.108
sensory perception GO:0007600 245 0.108
Zebrafish
purine nucleotide metabolic process GO:0006163 302 0.104
regulation of cell motility GO:2000145 236 0.102
subpallium development GO:0021544 20 0.100
adult behavior GO:0030534 135 0.098
cell division GO:0051301 120 0.098
neuron migration GO:0001764 122 0.097
establishment of organelle localization GO:0051656 122 0.089
Zebrafish
primary neural tube formation GO:0014020 95 0.087
limbic system development GO:0021761 72 0.087
eye photoreceptor cell development GO:0042462 31 0.085
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
anatomical structure homeostasis GO:0060249 145 0.085
organonitrogen compound catabolic process GO:1901565 264 0.084
epithelial tube formation GO:0072175 130 0.081
pallium development GO:0021543 120 0.078
hippocampus development GO:0021766 52 0.076
keratinocyte development GO:0003334 10 0.075
pigment granule localization GO:0051875 13 0.074
Zebrafish
camera type eye development GO:0043010 266 0.073
protein modification by small protein conjugation or removal GO:0070647 207 0.071
cellular amine metabolic process GO:0044106 44 0.070
cellular lipid metabolic process GO:0044255 323 0.069
tube formation GO:0035148 140 0.068
heterocycle catabolic process GO:0046700 280 0.067
nucleoside phosphate metabolic process GO:0006753 338 0.067
epidermis development GO:0008544 187 0.066
melanosome transport GO:0032402 11 0.065
Zebrafish
fertilization GO:0009566 127 0.065
ribonucleoside triphosphate catabolic process GO:0009203 199 0.063
positive regulation of cellular amine metabolic process GO:0033240 5 0.062
ribonucleoside triphosphate metabolic process GO:0009199 220 0.062
regulation of organelle organization GO:0033043 289 0.062
establishment of pigment granule localization GO:0051905 12 0.061
Zebrafish
purine containing compound catabolic process GO:0072523 213 0.060
glycosyl compound catabolic process GO:1901658 206 0.059
maintenance of location GO:0051235 89 0.058
multicellular organismal homeostasis GO:0048871 164 0.058
ribonucleoside metabolic process GO:0009119 245 0.056
carbohydrate derivative catabolic process GO:1901136 231 0.056
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
microtubule anchoring at microtubule organizing center GO:0072393 5 0.055
skin development GO:0043588 220 0.055
purine ribonucleotide metabolic process GO:0009150 290 0.054
purine nucleotide catabolic process GO:0006195 211 0.053
organelle localization GO:0051640 179 0.053
Zebrafish
amine metabolic process GO:0009308 45 0.053
protein localization to organelle GO:0033365 185 0.052
Human
neural tube development GO:0021915 160 0.052
embryonic epithelial tube formation GO:0001838 130 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.050
spermatid development GO:0007286 108 0.050
regulation of epithelial cell proliferation GO:0050678 141 0.049
negative regulation of cell proliferation GO:0008285 296 0.049
purine containing compound metabolic process GO:0072521 311 0.048
renal system development GO:0072001 225 0.048
purine nucleoside metabolic process GO:0042278 241 0.048
tissue homeostasis GO:0001894 115 0.047
regulation of cell projection organization GO:0031344 206 0.047
nucleoside metabolic process GO:0009116 246 0.047
connective tissue development GO:0061448 179 0.046
nucleotide metabolic process GO:0009117 332 0.046
trivalent inorganic cation transport GO:0072512 5 0.045
organophosphate catabolic process GO:0046434 232 0.045
cellular nitrogen compound catabolic process GO:0044270 280 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.043
retina development in camera type eye GO:0060041 119 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
photoreceptor cell maintenance GO:0045494 19 0.040
protein modification by small protein conjugation GO:0032446 187 0.040
cellular amino acid metabolic process GO:0006520 103 0.040
ribonucleotide metabolic process GO:0009259 291 0.039
nucleoside phosphate catabolic process GO:1901292 222 0.038
notch signaling pathway GO:0007219 71 0.038
Zebrafish
aromatic compound catabolic process GO:0019439 286 0.038
neural precursor cell proliferation GO:0061351 121 0.038
i kappab kinase nf kappab signaling GO:0007249 85 0.038
tube closure GO:0060606 91 0.038
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
glycosyl compound metabolic process GO:1901657 246 0.035
urogenital system development GO:0001655 261 0.035
germ cell development GO:0007281 185 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
nucleotide catabolic process GO:0009166 217 0.035
guanosine containing compound catabolic process GO:1901069 144 0.035
regulation of cell cycle GO:0051726 281 0.034
organic cyclic compound catabolic process GO:1901361 295 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
proteasomal protein catabolic process GO:0010498 98 0.033
embryonic organ morphogenesis GO:0048562 276 0.033
regulation of protein localization GO:0032880 231 0.033
hormone metabolic process GO:0042445 86 0.033
retina morphogenesis in camera type eye GO:0060042 45 0.033
purine nucleoside catabolic process GO:0006152 205 0.032
establishment or maintenance of cell polarity GO:0007163 86 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
protein catabolic process GO:0030163 221 0.032
appendage development GO:0048736 166 0.032
Zebrafish
purine ribonucleotide catabolic process GO:0009154 208 0.032
positive regulation of cellular catabolic process GO:0031331 148 0.031
epithelial cell development GO:0002064 159 0.031
cellular macromolecule catabolic process GO:0044265 206 0.031
spermatogenesis GO:0007283 284 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
pigment granule transport GO:0051904 12 0.031
Zebrafish
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.031
maintenance of protein location in nucleus GO:0051457 2 0.031
vesicle localization GO:0051648 86 0.030
Zebrafish
positive regulation of proteolysis GO:0045862 85 0.030
rab protein signal transduction GO:0032482 1 0.030
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.030
cellular homeostasis GO:0019725 240 0.029
digestive tract development GO:0048565 190 0.028
Zebrafish
cell junction maintenance GO:0034331 4 0.027
modification dependent protein catabolic process GO:0019941 133 0.027
spermatid differentiation GO:0048515 115 0.027
kidney development GO:0001822 213 0.027
nucleoside catabolic process GO:0009164 206 0.027
positive regulation of cell projection organization GO:0031346 95 0.027
cytokine mediated signaling pathway GO:0019221 115 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
gastrulation GO:0007369 116 0.026
Zebrafish
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
neural tube formation GO:0001841 108 0.026
regulation of cell cycle process GO:0010564 160 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
cognition GO:0050890 149 0.026
regulation of intracellular protein transport GO:0033157 82 0.025
chemosensory behavior GO:0007635 11 0.025
regulation of protein catabolic process GO:0042176 108 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
pigmentation GO:0043473 71 0.025
Zebrafish
cellular ketone metabolic process GO:0042180 84 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
gtp metabolic process GO:0046039 144 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
negative regulation of molecular function GO:0044092 258 0.024
positive regulation of organelle organization GO:0010638 128 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
dendrite development GO:0016358 115 0.024
peptide transport GO:0015833 133 0.024
exosomal secretion GO:1990182 1 0.024
cytoplasmic transport GO:0016482 234 0.023
neural tube closure GO:0001843 90 0.023
formation of organ boundary GO:0010160 1 0.023
regulation of nucleotide metabolic process GO:0006140 169 0.023
guanosine containing compound metabolic process GO:1901068 144 0.022
regulation of cell adhesion mediated by integrin GO:0033628 13 0.022
pole plasm assembly GO:0007315 2 0.022
epithelial cell proliferation GO:0050673 174 0.022
negative regulation of appetite GO:0032099 7 0.022
olfactory behavior GO:0042048 7 0.021
cell adhesion GO:0007155 329 0.021
positive regulation of growth GO:0045927 104 0.021
positive regulation of atpase activity GO:0032781 3 0.021
ras protein signal transduction GO:0007265 77 0.021
negative regulation of epithelial cell proliferation GO:0050680 64 0.021
nitrogen compound transport GO:0071705 271 0.021
neural retina development GO:0003407 41 0.021
cellularization GO:0007349 1 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
germ line stem cell division GO:0042078 2 0.021
neuron projection guidance GO:0097485 141 0.021
cell adhesion mediated by integrin GO:0033627 18 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
cellular protein catabolic process GO:0044257 155 0.020
peptide hormone secretion GO:0030072 109 0.020
regulation of intracellular transport GO:0032386 159 0.020
response to extracellular stimulus GO:0009991 127 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.020
determination of left right symmetry GO:0007368 80 0.020
Zebrafish
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
oocyte anterior posterior axis specification GO:0007314 2 0.020
digestive system development GO:0055123 200 0.020
Zebrafish
endomembrane system organization GO:0010256 147 0.019
limb development GO:0060173 166 0.019
membrane organization GO:0061024 245 0.019
negative regulation of synapse assembly GO:0051964 3 0.019
oocyte axis specification GO:0007309 2 0.019
learning GO:0007612 98 0.019
embryonic digit morphogenesis GO:0042733 56 0.019
glucose homeostasis GO:0042593 128 0.018
regulation of anatomical structure size GO:0090066 178 0.018
circulatory system process GO:0003013 197 0.018
transmembrane transport GO:0055085 412 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
regulation of cell adhesion GO:0030155 154 0.018
olfactory bulb development GO:0021772 30 0.018
segmentation GO:0035282 93 0.018
compound eye development GO:0048749 1 0.018
actin cytoskeleton organization GO:0030036 220 0.018
exocytosis GO:0006887 121 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
learning or memory GO:0007611 148 0.018
maternal determination of anterior posterior axis embryo GO:0008358 2 0.018
insulin secretion GO:0030073 89 0.017
oocyte construction GO:0007308 2 0.017
sensory perception of light stimulus GO:0050953 54 0.017
Zebrafish
protein localization to nucleus GO:0034504 121 0.017
renal tubule development GO:0061326 87 0.017
regulation of multi organism process GO:0043900 111 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
hormone secretion GO:0046879 128 0.017
embryonic appendage morphogenesis GO:0035113 126 0.017
cation transport GO:0006812 399 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
response to acid chemical GO:0001101 111 0.017
retrograde transport endosome to golgi GO:0042147 2 0.017
positive regulation of protein modification process GO:0031401 299 0.017
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.017
cytokinesis GO:0000910 17 0.016
positive regulation of cellular protein catabolic process GO:1903364 34 0.016
regulation of secretion GO:0051046 274 0.016
regulation of blood vessel size GO:0050880 56 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
associative learning GO:0008306 61 0.016
mitotic cell cycle GO:0000278 195 0.016
cell type specific apoptotic process GO:0097285 268 0.016
smoothened signaling pathway GO:0007224 105 0.016
multicellular organism growth GO:0035264 161 0.016
regulation of cellular response to growth factor stimulus GO:0090287 82 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
positive regulation of atp catabolic process GO:1903291 3 0.016
axonogenesis GO:0007409 274 0.016
muscle contraction GO:0006936 101 0.015
appendage morphogenesis GO:0035107 149 0.015
chemotaxis GO:0006935 247 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
positive regulation of protein catabolic process GO:0045732 60 0.015
protein ubiquitination GO:0016567 171 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
muscle cell differentiation GO:0042692 261 0.015
positive regulation of cell adhesion GO:0045785 80 0.015
apoptotic signaling pathway GO:0097190 306 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
protein localization to membrane GO:0072657 108 0.015
cell fate commitment GO:0045165 210 0.015
cellular glucose homeostasis GO:0001678 52 0.015
cellular chemical homeostasis GO:0055082 215 0.015
regulation of actin filament based process GO:0032970 99 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
left right pattern formation GO:0060972 23 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
response to retinoic acid GO:0032526 56 0.014
substantia nigra development GO:0021762 2 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
gtp catabolic process GO:0006184 143 0.014
regulation of endocytic recycling GO:2001135 3 0.014
regulation of homeostatic process GO:0032844 182 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
peptide secretion GO:0002790 114 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
rna processing GO:0006396 105 0.014
carbohydrate homeostasis GO:0033500 128 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
vascular process in circulatory system GO:0003018 62 0.014
regulation of cell division GO:0051302 76 0.014
microtubule organizing center organization GO:0031023 28 0.013
positive regulation of cell development GO:0010720 237 0.013
olfactory lobe development GO:0021988 32 0.013
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.013
regulation of response to food GO:0032095 10 0.013
regulation of neuron projection development GO:0010975 169 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
mitotic cytokinesis GO:0000281 4 0.013
tissue migration GO:0090130 68 0.013
negative regulation of nervous system development GO:0051961 156 0.013
artery smooth muscle contraction GO:0014824 2 0.013
centriole assembly GO:0098534 6 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
regulation of smoothened signaling pathway GO:0008589 58 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
somite development GO:0061053 81 0.012
sensory organ boundary specification GO:0008052 1 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
synapse organization GO:0050808 125 0.012
positive regulation of cell cycle GO:0045787 92 0.012
regulation of proteolysis GO:0030162 164 0.012
muscle tissue development GO:0060537 308 0.012
positive regulation of protein transport GO:0051222 93 0.012
cytokinetic process GO:0032506 2 0.012
negative regulation of growth GO:0045926 99 0.012
negative regulation of protein modification process GO:0031400 163 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
keratinocyte differentiation GO:0030216 48 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
regulation of protein transport GO:0051223 163 0.012
vasoconstriction GO:0042310 27 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
dna repair GO:0006281 107 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
regulation of cellular component size GO:0032535 121 0.012
cell maturation GO:0048469 127 0.012
digestive tract morphogenesis GO:0048546 147 0.012
Zebrafish
regulation of establishment of protein localization GO:0070201 181 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.011
inclusion body assembly GO:0070841 3 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
developmental maturation GO:0021700 193 0.011
intracellular protein transport GO:0006886 204 0.011
wnt signaling pathway GO:0016055 188 0.011
Human
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
regulation of kinase activity GO:0043549 249 0.011
skeletal muscle cell differentiation GO:0035914 66 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
striated muscle tissue development GO:0014706 293 0.011
centrosome organization GO:0051297 26 0.011
peptidyl amino acid modification GO:0018193 336 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
ameboidal type cell migration GO:0001667 128 0.011
smooth muscle contraction GO:0006939 44 0.011
maintenance of protein localization in organelle GO:0072595 2 0.011
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.011
regulation of ion transport GO:0043269 215 0.011
cardiac muscle tissue development GO:0048738 130 0.011
intracellular mrna localization GO:0008298 4 0.011
adherens junction maintenance GO:0034334 1 0.011
cation transmembrane transport GO:0098655 266 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
response to nutrient levels GO:0031667 109 0.011
sequestering of calcium ion GO:0051208 18 0.011
cellular response to monosaccharide stimulus GO:0071326 47 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
response to organonitrogen compound GO:0010243 246 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
dna metabolic process GO:0006259 303 0.010
regulation of tube size GO:0035150 57 0.010
immune effector process GO:0002252 321 0.010
cell fate determination involved in pattern specification GO:0060582 1 0.010
response to monosaccharide GO:0034284 67 0.010
regulation of embryonic development GO:0045995 71 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
regulation of mapk cascade GO:0043408 248 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
visual perception GO:0007601 52 0.010
Zebrafish
protein maturation GO:0051604 176 0.010
lymphocyte differentiation GO:0030098 242 0.010
atp metabolic process GO:0046034 75 0.010
regulation of transferase activity GO:0051338 263 0.010
positive regulation of nervous system development GO:0051962 221 0.010
regulation of centriole replication GO:0046599 1 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
positive regulation of neuron projection development GO:0010976 79 0.010

Arl6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.091
sensory system disease DOID:0050155 0 0.091
disease of anatomical entity DOID:7 0 0.091
eye and adnexa disease DOID:1492 0 0.091
nervous system disease DOID:863 0 0.091
eye disease DOID:5614 0 0.091
central nervous system disease DOID:331 0 0.040
brain disease DOID:936 0 0.040
epilepsy syndrome DOID:1826 0 0.022
electroclinical syndrome DOID:0050701 0 0.022
retinal degeneration DOID:8466 0 0.019
retinitis pigmentosa DOID:10584 0 0.015
immune system disease DOID:2914 0 0.012