Mus musculus

102 known processes

Nlrc5

NLR family, CARD domain containing 5

(Aliases: AI451557,NOD27,AK220210)

Nlrc5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
innate immune response GO:0045087 157 0.295
immune effector process GO:0002252 321 0.267
regulation of defense response GO:0031347 233 0.226
defense response to other organism GO:0098542 197 0.209
regulation of innate immune response GO:0045088 91 0.165
interferon beta biosynthetic process GO:0045350 4 0.149
activation of innate immune response GO:0002218 56 0.147
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.141
defense response to virus GO:0051607 68 0.134
positive regulation of innate immune response GO:0045089 80 0.100
cytokine production GO:0001816 319 0.089
cellular response to lipopolysaccharide GO:0071222 77 0.068
cellular response to lipid GO:0071396 145 0.064
activation of immune response GO:0002253 138 0.063
protein ubiquitination GO:0016567 171 0.061
protein modification by small protein conjugation or removal GO:0070647 207 0.059
purine containing compound metabolic process GO:0072521 311 0.059
cellular nitrogen compound catabolic process GO:0044270 280 0.058
heterocycle catabolic process GO:0046700 280 0.056
organic cyclic compound catabolic process GO:1901361 295 0.055
protein modification by small protein conjugation GO:0032446 187 0.054
interspecies interaction between organisms GO:0044419 83 0.053
defense response to gram positive bacterium GO:0050830 50 0.053
immune response regulating signaling pathway GO:0002764 125 0.052
positive regulation of defense response GO:0031349 124 0.052
aromatic compound catabolic process GO:0019439 286 0.051
positive regulation of cytokine production GO:0001819 174 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.049
innate immune response activating signal transduction GO:0002758 50 0.048
regulation of type i interferon production GO:0032479 22 0.048
negative regulation of multi organism process GO:0043901 68 0.047
regulation of defense response to virus GO:0050688 18 0.047
reactive oxygen species metabolic process GO:0072593 84 0.046
regulation of response to biotic stimulus GO:0002831 38 0.046
nucleoside phosphate catabolic process GO:1901292 222 0.046
response to molecule of bacterial origin GO:0002237 143 0.045
carbohydrate derivative catabolic process GO:1901136 231 0.045
ribonucleoside catabolic process GO:0042454 206 0.045
regulation of multi organism process GO:0043900 111 0.045
regulation of cytokine production GO:0001817 266 0.044
immune response activating signal transduction GO:0002757 116 0.043
regulation of hydrolase activity GO:0051336 246 0.041
cellular macromolecule catabolic process GO:0044265 206 0.041
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.041
type i interferon production GO:0032606 29 0.040
response to lipopolysaccharide GO:0032496 128 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
myeloid cell differentiation GO:0030099 233 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
cellular response to biotic stimulus GO:0071216 92 0.037
cellular response to cytokine stimulus GO:0071345 189 0.035
cation transport GO:0006812 399 0.034
cellular response to interferon beta GO:0035458 21 0.033
regulation of reactive oxygen species metabolic process GO:2000377 40 0.033
protein catabolic process GO:0030163 221 0.033
glycosyl compound metabolic process GO:1901657 246 0.032
regulation of defense response to bacterium GO:1900424 3 0.032
positive regulation of viral genome replication GO:0045070 2 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
viral gene expression GO:0019080 3 0.032
ribose phosphate metabolic process GO:0019693 291 0.031
macromolecule catabolic process GO:0009057 281 0.031
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.031
viral process GO:0016032 41 0.030
myeloid leukocyte differentiation GO:0002573 119 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
purine nucleoside metabolic process GO:0042278 241 0.030
rho protein signal transduction GO:0007266 32 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
positive regulation of immune effector process GO:0002699 107 0.029
ossification GO:0001503 216 0.029
leukocyte proliferation GO:0070661 172 0.029
organophosphate catabolic process GO:0046434 232 0.028
muscle tissue development GO:0060537 308 0.028
purine ribonucleoside catabolic process GO:0046130 205 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
nucleotide metabolic process GO:0009117 332 0.028
negative regulation of immune system process GO:0002683 209 0.027
leukocyte differentiation GO:0002521 342 0.027
negative regulation of molecular function GO:0044092 258 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
regulation of organelle organization GO:0033043 289 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
positive regulation of cell death GO:0010942 224 0.026
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
regulation of protein transport GO:0051223 163 0.025
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.025
response to organic cyclic compound GO:0014070 198 0.025
pattern recognition receptor signaling pathway GO:0002221 47 0.024
regulation of interferon beta production GO:0032648 13 0.024
lymphocyte mediated immunity GO:0002449 139 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
nucleotide catabolic process GO:0009166 217 0.024
ras protein signal transduction GO:0007265 77 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
dna metabolic process GO:0006259 303 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
interferon beta production GO:0032608 16 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
positive regulation of interferon alpha production GO:0032727 4 0.023
nucleoside metabolic process GO:0009116 246 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
guanosine containing compound catabolic process GO:1901069 144 0.022
toll like receptor signaling pathway GO:0002224 38 0.022
nucleoside catabolic process GO:0009164 206 0.022
cellular amino acid metabolic process GO:0006520 103 0.022
cellular protein catabolic process GO:0044257 155 0.021
guanosine containing compound metabolic process GO:1901068 144 0.021
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.021
viral transcription GO:0019083 3 0.021
purine containing compound catabolic process GO:0072523 213 0.021
modification dependent macromolecule catabolic process GO:0043632 133 0.021
positive regulation of type i interferon production GO:0032481 14 0.021
regulation of body fluid levels GO:0050878 162 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
defense response to bacterium GO:0042742 119 0.020
nitrogen compound transport GO:0071705 271 0.020
t cell activation GO:0042110 289 0.020
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.020
intracellular protein transport GO:0006886 204 0.019
mapk cascade GO:0000165 281 0.019
homeostasis of number of cells GO:0048872 210 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
regulation of interferon beta biosynthetic process GO:0045357 4 0.019
cell activation involved in immune response GO:0002263 126 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
protein maturation GO:0051604 176 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
apoptotic signaling pathway GO:0097190 306 0.018
negative regulation of viral process GO:0048525 23 0.018
ion transmembrane transport GO:0034220 361 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
leukocyte mediated immunity GO:0002443 174 0.018
transmembrane transport GO:0055085 412 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
antimicrobial peptide production GO:0002775 2 0.017
lymphocyte proliferation GO:0046651 164 0.017
gland development GO:0048732 330 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
viral genome replication GO:0019079 17 0.017
inflammatory response GO:0006954 244 0.017
viral life cycle GO:0019058 36 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
gtp catabolic process GO:0006184 143 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
cellular amine metabolic process GO:0044106 44 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
cell type specific apoptotic process GO:0097285 268 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
protein import GO:0017038 101 0.016
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.016
regulation of proteolysis GO:0030162 164 0.016
cellular homeostasis GO:0019725 240 0.015
negative regulation of protein processing GO:0010955 79 0.015
striated muscle tissue development GO:0014706 293 0.015
response to acid chemical GO:0001101 111 0.015
regulation of viral transcription GO:0046782 3 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
nuclear transport GO:0051169 139 0.015
protein localization to organelle GO:0033365 185 0.015
negative regulation of defense response GO:0031348 77 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
regulation of ion transport GO:0043269 215 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
cytokine metabolic process GO:0042107 71 0.015
skeletal system development GO:0001501 356 0.015
interferon gamma production GO:0032609 67 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
gtp metabolic process GO:0046039 144 0.014
peptidyl amino acid modification GO:0018193 336 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
regulation of cell killing GO:0031341 40 0.014
chromatin organization GO:0006325 206 0.014
response to organonitrogen compound GO:0010243 246 0.014
cellular ketone metabolic process GO:0042180 84 0.014
regulation of protein maturation GO:1903317 96 0.014
regulation of protein targeting GO:1903533 61 0.014
regulation of viral genome replication GO:0045069 13 0.013
regulation of ossification GO:0030278 112 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
negative regulation of viral genome replication GO:0045071 10 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
cation transmembrane transport GO:0098655 266 0.013
response to interferon gamma GO:0034341 34 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
leukocyte mediated cytotoxicity GO:0001909 62 0.013
regulation of protein complex assembly GO:0043254 83 0.013
regulation of protein processing GO:0070613 96 0.013
regulation of cell activation GO:0050865 289 0.013
defense response to protozoan GO:0042832 25 0.013
histone modification GO:0016570 159 0.013
protein processing GO:0016485 163 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
positive regulation of leukocyte mediated immunity GO:0002705 70 0.013
blood vessel morphogenesis GO:0048514 285 0.013
cytoplasmic transport GO:0016482 234 0.013
positive regulation of actin nucleation GO:0051127 3 0.013
positive regulation of viral entry into host cell GO:0046598 3 0.012
protein import into nucleus GO:0006606 95 0.012
negative regulation of leukocyte differentiation GO:1902106 51 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
negative regulation of proteolysis GO:0045861 74 0.012
negative regulation of nervous system development GO:0051961 156 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of membrane potential GO:0042391 192 0.012
lymphocyte differentiation GO:0030098 242 0.012
muscle cell differentiation GO:0042692 261 0.012
regulation of secretion by cell GO:1903530 249 0.012
negative regulation of cytokine production GO:0001818 84 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
cell killing GO:0001906 67 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
response to protozoan GO:0001562 28 0.012
carbohydrate metabolic process GO:0005975 230 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
regulation of cell cycle GO:0051726 281 0.012
positive regulation of antimicrobial humoral response GO:0002760 2 0.012
skeletal muscle organ development GO:0060538 163 0.012
negative regulation of protein modification process GO:0031400 163 0.011
negative regulation of viral transcription GO:0032897 3 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
interleukin 6 production GO:0032635 58 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
mrna metabolic process GO:0016071 84 0.011
rna interference GO:0016246 2 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
chromatin modification GO:0016568 187 0.011
sensory perception GO:0007600 245 0.011
peptide hormone secretion GO:0030072 109 0.011
single organism nuclear import GO:1902593 95 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
protein polyubiquitination GO:0000209 33 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
amine metabolic process GO:0009308 45 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
regulation of cell migration GO:0030334 219 0.011
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.011
angiogenesis GO:0001525 201 0.011
regulation of intracellular transport GO:0032386 159 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
protein targeting GO:0006605 143 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
cellular response to interferon alpha GO:0035457 4 0.011
myotube differentiation GO:0014902 105 0.010
spermatogenesis GO:0007283 284 0.010
regulation of anatomical structure size GO:0090066 178 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
negative regulation of cell cycle GO:0045786 123 0.010
carbohydrate homeostasis GO:0033500 128 0.010
mitochondrion organization GO:0007005 134 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
macromolecule methylation GO:0043414 120 0.010
neuronal action potential GO:0019228 54 0.010
metal ion homeostasis GO:0055065 189 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010

Nlrc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.017
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010