Mus musculus

397 known processes

Sirt2

sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)

(Aliases: 5730427M03Rik,SIR2L2,Sir2l)

Sirt2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
camera type eye development GO:0043010 266 0.268
regulation of cellular amino acid metabolic process GO:0006521 5 0.186
positive regulation of protein modification process GO:0031401 299 0.137
carbohydrate derivative catabolic process GO:1901136 231 0.127
regulation of hydrolase activity GO:0051336 246 0.126
kidney development GO:0001822 213 0.124
microtubule cytoskeleton organization GO:0000226 157 0.122
regulation of transferase activity GO:0051338 263 0.120
microtubule based process GO:0007017 236 0.119
regulation of cellular catabolic process GO:0031329 242 0.112
apoptotic signaling pathway GO:0097190 306 0.108
protein modification by small protein conjugation GO:0032446 187 0.106
cellular amino acid metabolic process GO:0006520 103 0.106
organelle fission GO:0048285 170 0.106
regulation of kinase activity GO:0043549 249 0.105
ribonucleotide metabolic process GO:0009259 291 0.102
macromolecule catabolic process GO:0009057 281 0.097
endomembrane system organization GO:0010256 147 0.088
nuclear division GO:0000280 158 0.087
regulation of cellular amine metabolic process GO:0033238 20 0.086
glycosyl compound metabolic process GO:1901657 246 0.086
synaptic transmission GO:0007268 329 0.085
regulation of proteolysis GO:0030162 164 0.084
anatomical structure homeostasis GO:0060249 145 0.083
cellular ketone metabolic process GO:0042180 84 0.077
meiotic cell cycle GO:0051321 122 0.076
cell division GO:0051301 120 0.075
negative regulation of intracellular signal transduction GO:1902532 167 0.075
nucleobase containing small molecule metabolic process GO:0055086 352 0.073
nucleoside phosphate metabolic process GO:0006753 338 0.073
protein ubiquitination GO:0016567 171 0.072
cellular amine metabolic process GO:0044106 44 0.072
regulation of cellular ketone metabolic process GO:0010565 66 0.070
cilium morphogenesis GO:0060271 102 0.069
regulation of anatomical structure size GO:0090066 178 0.067
amine metabolic process GO:0009308 45 0.066
oxidation reduction process GO:0055114 342 0.066
cellular lipid metabolic process GO:0044255 323 0.065
ubiquitin dependent protein catabolic process GO:0006511 129 0.063
organophosphate catabolic process GO:0046434 232 0.061
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.061
cellular response to dna damage stimulus GO:0006974 207 0.060
ras protein signal transduction GO:0007265 77 0.058
positive regulation of cellular amine metabolic process GO:0033240 5 0.057
mapk cascade GO:0000165 281 0.057
regulation of cell cycle process GO:0010564 160 0.056
ion transmembrane transport GO:0034220 361 0.056
defense response to other organism GO:0098542 197 0.054
positive regulation of cell death GO:0010942 224 0.053
sensory organ morphogenesis GO:0090596 242 0.052
ribonucleoside metabolic process GO:0009119 245 0.052
heterocycle catabolic process GO:0046700 280 0.051
glucose homeostasis GO:0042593 128 0.051
neuron death GO:0070997 154 0.050
regulation of organelle organization GO:0033043 289 0.049
positive regulation of cellular catabolic process GO:0031331 148 0.049
regulation of binding GO:0051098 111 0.049
nucleotide metabolic process GO:0009117 332 0.049
regulation of protein kinase activity GO:0045859 232 0.049
purine nucleoside triphosphate catabolic process GO:0009146 203 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
ribonucleotide catabolic process GO:0009261 208 0.047
positive regulation of protein phosphorylation GO:0001934 242 0.047
gliogenesis GO:0042063 141 0.047
regulation of cell cycle GO:0051726 281 0.047
chromosome segregation GO:0007059 48 0.046
autophagic vacuole assembly GO:0000045 13 0.046
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.045
embryonic organ morphogenesis GO:0048562 276 0.045
nucleoside metabolic process GO:0009116 246 0.045
nitrogen compound transport GO:0071705 271 0.044
regulation of apoptotic signaling pathway GO:2001233 197 0.044
aromatic compound catabolic process GO:0019439 286 0.043
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
transmembrane transport GO:0055085 412 0.042
response to organonitrogen compound GO:0010243 246 0.042
peptidyl amino acid modification GO:0018193 336 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.041
hematopoietic progenitor cell differentiation GO:0002244 143 0.041
regulation of chromosome organization GO:0033044 83 0.041
nucleoside triphosphate catabolic process GO:0009143 205 0.041
nucleotide catabolic process GO:0009166 217 0.040
epithelial cell development GO:0002064 159 0.040
negative regulation of molecular function GO:0044092 258 0.040
regulation of meiotic cell cycle GO:0051445 34 0.039
tissue homeostasis GO:0001894 115 0.039
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
multicellular organism growth GO:0035264 161 0.039
membrane organization GO:0061024 245 0.038
purine containing compound metabolic process GO:0072521 311 0.038
virion assembly GO:0019068 1 0.037
intracellular protein transport GO:0006886 204 0.037
cell type specific apoptotic process GO:0097285 268 0.037
cellular protein catabolic process GO:0044257 155 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
negative regulation of phosphorylation GO:0042326 166 0.036
dna metabolic process GO:0006259 303 0.036
Yeast
endocytosis GO:0006897 168 0.036
glial cell differentiation GO:0010001 131 0.036
response to organic cyclic compound GO:0014070 198 0.036
cellular response to growth factor stimulus GO:0071363 197 0.036
Human
cation transport GO:0006812 399 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
actin cytoskeleton organization GO:0030036 220 0.036
positive regulation of transferase activity GO:0051347 167 0.035
blood circulation GO:0008015 195 0.035
regulation of neuron death GO:1901214 134 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.035
protein maturation GO:0051604 176 0.034
spermatogenesis GO:0007283 284 0.034
meiotic nuclear division GO:0007126 115 0.033
regulation of protein maturation GO:1903317 96 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.033
positive regulation of chromosome segregation GO:0051984 4 0.033
cellular homeostasis GO:0019725 240 0.032
multicellular organismal homeostasis GO:0048871 164 0.032
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
nucleoside catabolic process GO:0009164 206 0.032
glycerolipid metabolic process GO:0046486 122 0.032
positive regulation of organelle organization GO:0010638 128 0.032
regulation of cellular component biogenesis GO:0044087 181 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.032
cellular macromolecule catabolic process GO:0044265 206 0.032
energy derivation by oxidation of organic compounds GO:0015980 77 0.032
cell maturation GO:0048469 127 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
organonitrogen compound catabolic process GO:1901565 264 0.031
developmental maturation GO:0021700 193 0.031
regulation of body fluid levels GO:0050878 162 0.031
renal system development GO:0072001 225 0.031
regulation of intracellular protein transport GO:0033157 82 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.030
regulation of exit from mitosis GO:0007096 1 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
regulation of cellular component size GO:0032535 121 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
gonad development GO:0008406 141 0.029
protein localization to membrane GO:0072657 108 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.029
protein catabolic process GO:0030163 221 0.029
modification dependent macromolecule catabolic process GO:0043632 133 0.029
metal ion homeostasis GO:0055065 189 0.029
defense response to bacterium GO:0042742 119 0.029
regulation of ion transport GO:0043269 215 0.029
cellular chemical homeostasis GO:0055082 215 0.028
lipid biosynthetic process GO:0008610 179 0.028
vacuole organization GO:0007033 38 0.028
organelle assembly GO:0070925 177 0.028
regulation of protein localization GO:0032880 231 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
positive regulation of kinase activity GO:0033674 155 0.028
positive regulation of mapk cascade GO:0043410 170 0.027
skin development GO:0043588 220 0.027
ameboidal type cell migration GO:0001667 128 0.027
negative regulation of cellular component organization GO:0051129 194 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
dephosphorylation GO:0016311 129 0.027
leukocyte differentiation GO:0002521 342 0.027
neuron apoptotic process GO:0051402 142 0.027
cellular metal ion homeostasis GO:0006875 151 0.027
positive regulation of mitotic cell cycle GO:0045931 41 0.027
intrinsic apoptotic signaling pathway GO:0097193 132 0.027
regulation of vesicle mediated transport GO:0060627 139 0.026
regulation of cytoplasmic transport GO:1903649 112 0.026
cellular divalent inorganic cation homeostasis GO:0072503 127 0.026
regulation of cell migration GO:0030334 219 0.025
central nervous system neuron differentiation GO:0021953 162 0.025
ensheathment of neurons GO:0007272 76 0.025
leukocyte chemotaxis GO:0030595 69 0.025
lamellipodium organization GO:0097581 29 0.025
regulation of protein catabolic process GO:0042176 108 0.025
small molecule biosynthetic process GO:0044283 132 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.024
sequestering of metal ion GO:0051238 19 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
mitotic nuclear division GO:0007067 48 0.024
retina development in camera type eye GO:0060041 119 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
positive regulation of necrotic cell death GO:0010940 1 0.024
regulation of secretion GO:0051046 274 0.024
inorganic cation transmembrane transport GO:0098662 207 0.024
epidermis development GO:0008544 187 0.023
plasma membrane organization GO:0007009 90 0.023
chemotaxis GO:0006935 247 0.023
regulation of mapk cascade GO:0043408 248 0.023
regulation of lipoprotein lipase activity GO:0051004 4 0.023
mitotic cell cycle GO:0000278 195 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
Human
purine nucleoside metabolic process GO:0042278 241 0.022
regionalization GO:0003002 337 0.022
male gamete generation GO:0048232 285 0.022
regulation of system process GO:0044057 200 0.022
locomotory behavior GO:0007626 195 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.021
positive regulation of triglyceride lipase activity GO:0061365 3 0.021
circulatory system process GO:0003013 197 0.021
regulation of mitotic cell cycle GO:0007346 126 0.021
placenta development GO:0001890 140 0.021
cellular response to nutrient levels GO:0031669 64 0.021
regulation of map kinase activity GO:0043405 120 0.021
protein localization to organelle GO:0033365 185 0.021
regulation of t cell activation GO:0050863 170 0.021
germ cell development GO:0007281 185 0.021
regulation of membrane potential GO:0042391 192 0.020
synapsis GO:0007129 34 0.020
t cell activation GO:0042110 289 0.020
heart morphogenesis GO:0003007 178 0.020
cellular protein complex assembly GO:0043623 116 0.020
heart contraction GO:0060047 93 0.020
antimicrobial peptide production GO:0002775 2 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
cytoplasmic transport GO:0016482 234 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
leukocyte migration GO:0050900 124 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
digestive system development GO:0055123 200 0.019
negative regulation of proteolysis GO:0045861 74 0.019
inflammatory response GO:0006954 244 0.019
negative regulation of protein modification process GO:0031400 163 0.019
polysaccharide metabolic process GO:0005976 39 0.019
mitotic cell cycle process GO:1903047 159 0.019
regulation of secretion by cell GO:1903530 249 0.019
regulation of multi organism process GO:0043900 111 0.019
kidney epithelium development GO:0072073 121 0.019
regulation of antimicrobial humoral response GO:0002759 3 0.019
urogenital system development GO:0001655 261 0.019
regulation of cell size GO:0008361 72 0.019
chromatin modification GO:0016568 187 0.019
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
positive regulation of nuclear division GO:0051785 27 0.019
protein processing GO:0016485 163 0.019
establishment of vesicle localization GO:0051650 81 0.019
action potential GO:0001508 78 0.019
cellular response to oxidative stress GO:0034599 76 0.018
cation transmembrane transport GO:0098655 266 0.018
regulation of cell activation GO:0050865 289 0.018
regulation of homeostatic process GO:0032844 182 0.018
developmental growth involved in morphogenesis GO:0060560 138 0.018
guanosine containing compound metabolic process GO:1901068 144 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
regulation of cell motility GO:2000145 236 0.018
organic acid biosynthetic process GO:0016053 86 0.018
negative regulation of kinase activity GO:0033673 81 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
Human
lens development in camera type eye GO:0002088 62 0.018
organelle localization GO:0051640 179 0.017
positive regulation of cell cycle process GO:0090068 61 0.017
body fluid secretion GO:0007589 53 0.017
neutral lipid metabolic process GO:0006638 57 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
t cell differentiation GO:0030217 174 0.017
extracellular matrix organization GO:0030198 147 0.017
cation homeostasis GO:0055080 212 0.017
lymphocyte homeostasis GO:0002260 64 0.017
regulation of cell adhesion GO:0030155 154 0.017
development of primary sexual characteristics GO:0045137 143 0.017
leukocyte homeostasis GO:0001776 79 0.017
regulation of cellular protein catabolic process GO:1903362 61 0.017
cellular polysaccharide catabolic process GO:0044247 5 0.017
cellular glucan metabolic process GO:0006073 32 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
Human
establishment of melanosome localization GO:0032401 11 0.017
peptide transport GO:0015833 133 0.017
response to peptide GO:1901652 136 0.017
negative regulation of cellular catabolic process GO:0031330 47 0.017
Human
extracellular structure organization GO:0043062 148 0.017
cellular ion homeostasis GO:0006873 165 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
Human
positive regulation of apoptotic process GO:0043065 217 0.017
regulation of ossification GO:0030278 112 0.017
positive regulation of chromosome organization GO:2001252 33 0.017
regulation of blood pressure GO:0008217 93 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
cell chemotaxis GO:0060326 81 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
negative regulation of neuron death GO:1901215 98 0.016
response to extracellular stimulus GO:0009991 127 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
myeloid cell differentiation GO:0030099 233 0.016
response to growth factor GO:0070848 198 0.016
Human
negative regulation of phosphate metabolic process GO:0045936 184 0.016
interspecies interaction between organisms GO:0044419 83 0.016
positive regulation of cell motility GO:2000147 116 0.016
lymphocyte differentiation GO:0030098 242 0.016
regulation of protein transport GO:0051223 163 0.016
intracellular receptor signaling pathway GO:0030522 74 0.016
positive regulation of secretion GO:0051047 130 0.016
negative regulation of transferase activity GO:0051348 85 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.015
sequestering of calcium ion GO:0051208 18 0.015
epithelial cell proliferation GO:0050673 174 0.015
regulation of cellular response to growth factor stimulus GO:0090287 82 0.015
sensory system development GO:0048880 3 0.015
developmental cell growth GO:0048588 84 0.015
eye photoreceptor cell differentiation GO:0001754 41 0.015
glycoprotein metabolic process GO:0009100 116 0.015
muscle cell differentiation GO:0042692 261 0.015
blood vessel morphogenesis GO:0048514 285 0.015
protein kinase b signaling GO:0043491 74 0.015
Human
purine containing compound catabolic process GO:0072523 213 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
carbohydrate metabolic process GO:0005975 230 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
organic hydroxy compound transport GO:0015850 93 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
regulation of cell projection organization GO:0031344 206 0.015
epithelium migration GO:0090132 63 0.015
regulation of protein processing GO:0070613 96 0.015
axonogenesis GO:0007409 274 0.015
positive regulation of intracellular transport GO:0032388 70 0.015
protein localization to plasma membrane GO:0072659 57 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
regulation of neural precursor cell proliferation GO:2000177 70 0.014
Rat
maintenance of location GO:0051235 89 0.014
negative regulation of dna replication GO:0008156 4 0.014
homeostasis of number of cells GO:0048872 210 0.014
ruffle organization GO:0031529 16 0.014
divalent inorganic cation transport GO:0072511 178 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
response to lipopolysaccharide GO:0032496 128 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
ossification GO:0001503 216 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
transmission of nerve impulse GO:0019226 76 0.014
negative regulation of protein processing GO:0010955 79 0.014
negative regulation of homeostatic process GO:0032845 71 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
cellular polysaccharide metabolic process GO:0044264 38 0.014
skeletal system development GO:0001501 356 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
neurotransmitter secretion GO:0007269 62 0.014
regulation of cytokine production GO:0001817 266 0.014
autophagy GO:0006914 45 0.014
Human
response to inorganic substance GO:0010035 96 0.014
cellular response to abiotic stimulus GO:0071214 56 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
response to radiation GO:0009314 165 0.014
negative regulation of nervous system development GO:0051961 156 0.014
Rat
carbohydrate homeostasis GO:0033500 128 0.014
regulation of vasculature development GO:1901342 88 0.014
negative regulation of cell aging GO:0090344 5 0.014
forebrain development GO:0030900 302 0.014
cell fate commitment GO:0045165 210 0.014
respiratory system development GO:0060541 190 0.013
cellular response to glucose stimulus GO:0071333 45 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
nephron development GO:0072006 109 0.013
positive regulation of binding GO:0051099 49 0.013
regulation of neurotransmitter transport GO:0051588 35 0.013
negative regulation of organelle organization GO:0010639 90 0.013
heart process GO:0003015 94 0.013
regulation of actin filament based process GO:0032970 99 0.013
fatty acid biosynthetic process GO:0006633 41 0.013
wound healing GO:0042060 157 0.013
embryonic skeletal system development GO:0048706 120 0.013
rho protein signal transduction GO:0007266 32 0.013
glucan metabolic process GO:0044042 32 0.013
regulation of endocytosis GO:0030100 69 0.013
gland development GO:0048732 330 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
cellular response to lipid GO:0071396 145 0.013
lipid catabolic process GO:0016042 69 0.013
regulation of intracellular transport GO:0032386 159 0.013
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.013
wnt signaling pathway GO:0016055 188 0.013
innate immune response GO:0045087 157 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
chromatin organization GO:0006325 206 0.013
regulation of inflammatory response GO:0050727 147 0.013
regulation of peptidase activity GO:0052547 96 0.013
embryonic placenta development GO:0001892 98 0.013
spermatid differentiation GO:0048515 115 0.013
macroautophagy GO:0016236 21 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.013
regulation of protein kinase b signaling GO:0051896 56 0.013
leukocyte proliferation GO:0070661 172 0.013
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.013
regulation of response to wounding GO:1903034 189 0.013
single organism cell adhesion GO:0098602 156 0.013
regulation of mitosis GO:0007088 29 0.013
positive regulation of cell cycle GO:0045787 92 0.013
calcium ion transport GO:0006816 159 0.013
neurotransmitter transport GO:0006836 76 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
neuron projection extension GO:1990138 64 0.012
response to molecule of fungal origin GO:0002238 4 0.012
necrotic cell death GO:0070265 30 0.012
cell junction organization GO:0034330 77 0.012
response to peptide hormone GO:0043434 127 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
phosphatidic acid biosynthetic process GO:0006654 2 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
cellular response to external stimulus GO:0071496 88 0.012
calcium ion homeostasis GO:0055074 127 0.012
regulation of protein ubiquitination GO:0031396 52 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
regulation of lamellipodium morphogenesis GO:2000392 1 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
lateral inhibition GO:0046331 1 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
lipid transport GO:0006869 98 0.012
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.012
regulation of feeding behavior GO:0060259 3 0.012
protein polymerization GO:0051258 57 0.012
myelination in peripheral nervous system GO:0022011 19 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
muscle tissue development GO:0060537 308 0.012
Human
vesicle localization GO:0051648 86 0.012
regulation of protein complex assembly GO:0043254 83 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
metencephalon development GO:0022037 89 0.012
regulation of protein binding GO:0043393 60 0.012
protein acylation GO:0043543 64 0.012
Mouse
endoplasmic reticulum tubular network organization GO:0071786 1 0.012
response to oxygen levels GO:0070482 62 0.012
Human
single fertilization GO:0007338 82 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
regulation of calcium ion transport GO:0051924 69 0.012
neuron neuron synaptic transmission GO:0007270 69 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
nephron epithelium development GO:0072009 92 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of angiogenesis GO:0045765 81 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
anion transport GO:0006820 177 0.011
connective tissue development GO:0061448 179 0.011
cell adhesion GO:0007155 329 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
sensory perception GO:0007600 245 0.011
regulation of defense response GO:0031347 233 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of osteoblast differentiation GO:0045667 67 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
myeloid leukocyte migration GO:0097529 57 0.011
covalent chromatin modification GO:0016569 163 0.011
positive regulation of growth GO:0045927 104 0.011
cellular response to x ray GO:0071481 2 0.011
response to insulin GO:0032868 100 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
cellular response to starvation GO:0009267 57 0.011
multi multicellular organism process GO:0044706 109 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.011
tube formation GO:0035148 140 0.011
synaptic vesicle priming GO:0016082 8 0.011
regulation of neuron differentiation GO:0045664 281 0.011
negative regulation of protein maturation GO:1903318 79 0.010
mitochondrion degradation GO:0000422 3 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
cell substrate adhesion GO:0031589 130 0.010
amide transport GO:0042886 138 0.010
meiotic cell cycle process GO:1903046 77 0.010
myeloid cell homeostasis GO:0002262 114 0.010
peptide secretion GO:0002790 114 0.010
regulation of neuron projection development GO:0010975 169 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
telencephalon development GO:0021537 186 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
pigmentation GO:0043473 71 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
regulation of hormone levels GO:0010817 211 0.010
meiosis i GO:0007127 60 0.010
striated muscle cell development GO:0055002 125 0.010
mesoderm development GO:0007498 100 0.010
branching morphogenesis of an epithelial tube GO:0048754 159 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
myelination GO:0042552 74 0.010

Sirt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
nervous system disease DOID:863 0 0.060
disease of metabolism DOID:0014667 0 0.048
immune system disease DOID:2914 0 0.047
central nervous system disease DOID:331 0 0.046
hematopoietic system disease DOID:74 0 0.025
neurodegenerative disease DOID:1289 0 0.025
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
retinal disease DOID:5679 0 0.015
retinal degeneration DOID:8466 0 0.015
eye disease DOID:5614 0 0.015