Mus musculus

7 known processes

Hspb2

heat shock protein 2

(Aliases: 27kDa,2810021G24Rik,MKBP,HSP27)

Hspb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle cell development GO:0055002 125 0.769
muscle cell development GO:0055001 133 0.746
cellular component assembly involved in morphogenesis GO:0010927 139 0.651
sarcomere organization GO:0045214 24 0.613
muscle tissue development GO:0060537 308 0.601
muscle contraction GO:0006936 101 0.593
organelle assembly GO:0070925 177 0.576
striated muscle tissue development GO:0014706 293 0.558
muscle fiber development GO:0048747 76 0.534
striated muscle contraction GO:0006941 45 0.486
actomyosin structure organization GO:0031032 56 0.466
actin cytoskeleton organization GO:0030036 220 0.452
Mouse
myotube differentiation GO:0014902 105 0.448
skeletal muscle fiber development GO:0048741 58 0.379
muscle cell differentiation GO:0042692 261 0.343
neurotransmitter transport GO:0006836 76 0.337
muscle system process GO:0003012 141 0.312
cardiac muscle cell differentiation GO:0055007 69 0.276
cardiac muscle cell development GO:0055013 39 0.267
heart contraction GO:0060047 93 0.260
skeletal muscle organ development GO:0060538 163 0.259
cardiac muscle contraction GO:0060048 32 0.255
actin filament based movement GO:0030048 23 0.232
skeletal myofibril assembly GO:0014866 4 0.217
actin mediated cell contraction GO:0070252 15 0.179
striated muscle myosin thick filament assembly GO:0071688 1 0.158
cellular amino acid metabolic process GO:0006520 103 0.157
cardiac muscle tissue development GO:0048738 130 0.151
skeletal muscle adaptation GO:0043501 16 0.147
actin filament organization GO:0007015 113 0.146
Mouse
cellular protein complex assembly GO:0043623 116 0.143
Mouse
mitochondrion organization GO:0007005 134 0.142
Mouse
skeletal muscle thin filament assembly GO:0030240 2 0.139
myosin filament organization GO:0031033 3 0.135
cell substrate adhesion GO:0031589 130 0.134
inorganic ion transmembrane transport GO:0098660 234 0.131
transmembrane transport GO:0055085 412 0.131
blood circulation GO:0008015 195 0.128
endomembrane system organization GO:0010256 147 0.126
nucleoside phosphate catabolic process GO:1901292 222 0.114
regulation of neurotransmitter levels GO:0001505 87 0.108
cation transport GO:0006812 399 0.106
ventricular cardiac muscle cell action potential GO:0086005 4 0.106
regulation of cell substrate adhesion GO:0010810 73 0.096
myofibril assembly GO:0030239 34 0.095
regulation of system process GO:0044057 200 0.093
synaptic transmission GO:0007268 329 0.091
ribonucleoside catabolic process GO:0042454 206 0.090
regulation of transmembrane transport GO:0034762 128 0.090
regulation of skeletal muscle contraction GO:0014819 3 0.088
ion transmembrane transport GO:0034220 361 0.087
myotube cell development GO:0014904 60 0.087
organelle localization GO:0051640 179 0.084
regulation of muscle contraction GO:0006937 49 0.084
apoptotic signaling pathway GO:0097190 306 0.083
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.082
cellular amine metabolic process GO:0044106 44 0.081
syncytium formation by plasma membrane fusion GO:0000768 42 0.080
regulation of ion transmembrane transport GO:0034765 119 0.079
protein localization to membrane GO:0072657 108 0.078
myosin filament assembly GO:0031034 2 0.078
regulation of heart rate GO:0002027 36 0.078
microtubule cytoskeleton organization GO:0000226 157 0.075
ribose phosphate metabolic process GO:0019693 291 0.075
circulatory system process GO:0003013 197 0.075
regulation of nucleotide catabolic process GO:0030811 122 0.073
regulation of cellular response to growth factor stimulus GO:0090287 82 0.072
cardiocyte differentiation GO:0035051 87 0.072
response to inorganic substance GO:0010035 96 0.067
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.067
muscle tissue morphogenesis GO:0060415 53 0.067
membrane organization GO:0061024 245 0.065
regulation of blood circulation GO:1903522 93 0.064
inorganic cation transmembrane transport GO:0098662 207 0.064
microtubule based process GO:0007017 236 0.063
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.061
regulation of metal ion transport GO:0010959 106 0.061
cardiac chamber development GO:0003205 108 0.060
sodium ion export GO:0071436 2 0.060
regulation of membrane potential GO:0042391 192 0.060
syncytium formation GO:0006949 43 0.059
cation homeostasis GO:0055080 212 0.059
cellular ketone metabolic process GO:0042180 84 0.058
regulation of cellular amine metabolic process GO:0033238 20 0.057
uterus morphogenesis GO:0061038 2 0.057
tubulin complex biogenesis GO:0072668 2 0.056
Mouse
transition between fast and slow fiber GO:0014883 9 0.056
purine nucleoside triphosphate metabolic process GO:0009144 226 0.056
regulation of membrane depolarization GO:0003254 11 0.054
regulation of intracellular transport GO:0032386 159 0.054
nucleoside catabolic process GO:0009164 206 0.054
regulation of muscle system process GO:0090257 80 0.053
purine nucleotide catabolic process GO:0006195 211 0.052
positive regulation of cell motility GO:2000147 116 0.052
cardiac muscle fiber development GO:0048739 4 0.052
sodium ion export from cell GO:0036376 1 0.052
cation transmembrane transport GO:0098655 266 0.051
negative regulation of phosphorus metabolic process GO:0010563 184 0.051
Mouse
nucleotide catabolic process GO:0009166 217 0.051
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.051
divalent inorganic cation transport GO:0072511 178 0.050
extracellular structure organization GO:0043062 148 0.050
glycosyl compound catabolic process GO:1901658 206 0.050
cellular ion homeostasis GO:0006873 165 0.050
maintenance of location GO:0051235 89 0.049
sequestering of calcium ion GO:0051208 18 0.049
positive regulation of ion transport GO:0043270 65 0.049
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.049
aromatic compound catabolic process GO:0019439 286 0.048
intracellular protein transport GO:0006886 204 0.048
heart process GO:0003015 94 0.048
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.047
regulation of heart contraction GO:0008016 77 0.047
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.047
heart morphogenesis GO:0003007 178 0.047
neurotransmitter secretion GO:0007269 62 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.046
embryonic epithelial tube formation GO:0001838 130 0.045
ossification GO:0001503 216 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.045
purine ribonucleoside catabolic process GO:0046130 205 0.044
cardiac myofibril assembly GO:0055003 12 0.044
cardiac muscle tissue morphogenesis GO:0055008 44 0.044
regulation of ion homeostasis GO:2000021 64 0.044
regulation of cellular response to stress GO:0080135 159 0.043
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
central nervous system morphogenesis GO:0021551 2 0.043
cellular metal ion homeostasis GO:0006875 151 0.043
purine nucleotide metabolic process GO:0006163 302 0.043
glycosyl compound metabolic process GO:1901657 246 0.042
cardiac cell development GO:0055006 41 0.042
purine containing compound catabolic process GO:0072523 213 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.041
positive regulation of glial cell proliferation GO:0060252 4 0.041
skeletal muscle tissue regeneration GO:0043403 20 0.041
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
angiogenesis GO:0001525 201 0.041
protein ubiquitination GO:0016567 171 0.041
midgut development GO:0007494 4 0.040
regulation of organelle organization GO:0033043 289 0.040
cellular chemical homeostasis GO:0055082 215 0.040
metal ion homeostasis GO:0055065 189 0.039
regulation of atp catabolic process GO:1903289 9 0.039
renal system development GO:0072001 225 0.039
regulation of transporter activity GO:0032409 57 0.039
ribonucleoside metabolic process GO:0009119 245 0.039
organic cyclic compound catabolic process GO:1901361 295 0.039
endocytosis GO:0006897 168 0.039
regulation of ion transmembrane transporter activity GO:0032412 54 0.039
regulation of endocytosis GO:0030100 69 0.039
ribonucleoside triphosphate catabolic process GO:0009203 199 0.038
actin myosin filament sliding GO:0033275 1 0.038
organonitrogen compound catabolic process GO:1901565 264 0.038
heterocycle catabolic process GO:0046700 280 0.038
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
regulation of kinase activity GO:0043549 249 0.037
Mouse
lung development GO:0030324 164 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
respiratory tube development GO:0030323 167 0.037
sensory perception GO:0007600 245 0.037
cell type specific apoptotic process GO:0097285 268 0.037
positive regulation of apoptotic process GO:0043065 217 0.036
locomotory behavior GO:0007626 195 0.036
organophosphate catabolic process GO:0046434 232 0.036
mitotic cell cycle GO:0000278 195 0.036
cell matrix adhesion GO:0007160 68 0.036
mesonephric duct morphogenesis GO:0072180 4 0.036
regulation of atp metabolic process GO:1903578 17 0.035
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.035
regulation of microtubule cytoskeleton organization GO:0070507 37 0.035
cardiac ventricle development GO:0003231 83 0.035
regulation of ion transport GO:0043269 215 0.035
gas homeostasis GO:0033483 3 0.035
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.035
regulation of muscle tissue development GO:1901861 97 0.035
nucleoside metabolic process GO:0009116 246 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
muscle filament sliding GO:0030049 1 0.035
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.034
myoblast differentiation GO:0045445 52 0.034
adult locomotory behavior GO:0008344 91 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.034
regulation of muscle adaptation GO:0043502 31 0.034
protein catabolic process GO:0030163 221 0.034
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.034
ribonucleotide catabolic process GO:0009261 208 0.033
macromolecular complex disassembly GO:0032984 43 0.033
regulation of actin cytoskeleton organization GO:0032956 84 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
multicellular organismal signaling GO:0035637 91 0.032
regulation of actin filament based process GO:0032970 99 0.032
negative regulation of phosphate metabolic process GO:0045936 184 0.032
Mouse
regulation of cell motility GO:2000145 236 0.031
microtubule polymerization or depolymerization GO:0031109 26 0.031
potassium ion homeostasis GO:0055075 4 0.031
wnt signaling pathway GO:0016055 188 0.031
embryonic limb morphogenesis GO:0030326 126 0.031
apoptotic process involved in morphogenesis GO:0060561 25 0.030
Mouse
regulation of myotube differentiation GO:0010830 62 0.030
mitotic cell cycle process GO:1903047 159 0.030
maintenance of cell number GO:0098727 3 0.030
regulation of striated muscle cell differentiation GO:0051153 81 0.030
positive regulation of secretion GO:0051047 130 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.030
epithelial tube formation GO:0072175 130 0.030
protein processing GO:0016485 163 0.030
Mouse
purine nucleoside catabolic process GO:0006152 205 0.030
regulation of apoptotic signaling pathway GO:2001233 197 0.029
Mouse
regulation of calcium ion transport GO:0051924 69 0.029
atp metabolic process GO:0046034 75 0.029
negative regulation of protein complex disassembly GO:0043242 22 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.029
glycoprotein biosynthetic process GO:0009101 89 0.028
ribonucleoside monophosphate catabolic process GO:0009158 57 0.028
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
plasma membrane organization GO:0007009 90 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
neural tube closure GO:0001843 90 0.028
macromolecule catabolic process GO:0009057 281 0.027
regulation of nucleoside metabolic process GO:0009118 130 0.027
central nervous system vasculogenesis GO:0022009 3 0.027
anion transport GO:0006820 177 0.027
peripheral nervous system axon regeneration GO:0014012 2 0.027
cytoplasmic transport GO:0016482 234 0.027
protein localization to organelle GO:0033365 185 0.027
negative regulation of protein modification process GO:0031400 163 0.027
Mouse
organic anion transport GO:0015711 137 0.027
meiotic cell cycle GO:0051321 122 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
wound healing GO:0042060 157 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
Mouse
negative regulation of protein depolymerization GO:1901880 21 0.026
carboxylic acid transport GO:0046942 100 0.026
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.026
regulation of microtubule based process GO:0032886 52 0.026
positive regulation of apoptotic signaling pathway GO:2001235 95 0.026
divalent metal ion transport GO:0070838 172 0.026
regulation of schwann cell proliferation GO:0010624 2 0.025
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.025
generation of precursor metabolites and energy GO:0006091 103 0.025
positive regulation of cell development GO:0010720 237 0.025
interleukin 8 production GO:0032637 4 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.025
morphogenesis of a polarized epithelium GO:0001738 37 0.025
protein maturation GO:0051604 176 0.025
Mouse
response to uv a GO:0070141 1 0.025
Mouse
calcium ion homeostasis GO:0055074 127 0.024
cardiac muscle cell contraction GO:0086003 7 0.024
regulation of synaptic plasticity GO:0048167 87 0.024
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
cell adhesion GO:0007155 329 0.024
negative regulation of molecular function GO:0044092 258 0.024
Mouse
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.023
regulation of myoblast differentiation GO:0045661 29 0.023
purine containing compound metabolic process GO:0072521 311 0.023
regulation of skeletal muscle fiber development GO:0048742 36 0.023
protein targeting GO:0006605 143 0.023
ventricular cardiac myofibril assembly GO:0055005 3 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
Mouse
camera type eye development GO:0043010 266 0.023
Mouse
regulation of interleukin 8 production GO:0032677 3 0.023
branching morphogenesis of an epithelial tube GO:0048754 159 0.023
neuromuscular process GO:0050905 99 0.022
calcium ion transport GO:0006816 159 0.022
membrane lipid biosynthetic process GO:0046467 32 0.022
immune effector process GO:0002252 321 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
negative regulation of androgen biosynthetic process GO:2000180 1 0.022
positive regulation of nervous system development GO:0051962 221 0.022
potassium ion transport GO:0006813 52 0.022
release of sequestered calcium ion into cytosol GO:0051209 42 0.022
negative regulation of hormone biosynthetic process GO:0032353 4 0.022
nucleotide metabolic process GO:0009117 332 0.022
acetylcholine transport GO:0015870 2 0.022
positive regulation of cell death GO:0010942 224 0.022
leukocyte differentiation GO:0002521 342 0.022
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
Mouse
regulation of fibroblast growth factor production GO:0090270 4 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
atp catabolic process GO:0006200 55 0.021
positive regulation of neuron projection development GO:0010976 79 0.021
peptidyl amino acid modification GO:0018193 336 0.021
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.021
negative regulation of organelle organization GO:0010639 90 0.021
sclerotome development GO:0061056 4 0.021
cellular protein complex disassembly GO:0043624 36 0.021
spemann organizer formation GO:0060061 2 0.021
regulation of mapk cascade GO:0043408 248 0.021
regulation of anatomical structure size GO:0090066 178 0.021
tube closure GO:0060606 91 0.021
myeloid leukocyte differentiation GO:0002573 119 0.020
renal outer medulla development GO:0072054 2 0.020
protein depolymerization GO:0051261 34 0.020
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.020
positive regulation of interleukin 1 secretion GO:0050716 14 0.020
ear development GO:0043583 200 0.020
extracellular matrix organization GO:0030198 147 0.020
sa node cell action potential GO:0086015 4 0.020
leukocyte activation involved in immune response GO:0002366 126 0.020
sodium ion transmembrane transport GO:0035725 49 0.020
t cell proliferation GO:0042098 120 0.020
meiotic nuclear division GO:0007126 115 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.020
urogenital system development GO:0001655 261 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
regulation of protein maturation GO:1903317 96 0.020
Mouse
sequestering of metal ion GO:0051238 19 0.020
positive regulation of atpase activity GO:0032781 3 0.020
embryonic appendage morphogenesis GO:0035113 126 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
interleukin 8 secretion GO:0072606 3 0.019
regulation of cysteine type endopeptidase activity GO:2000116 65 0.019
Mouse
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.019
atrial cardiac muscle tissue development GO:0003228 5 0.019
bronchiole development GO:0060435 3 0.019
development of primary sexual characteristics GO:0045137 143 0.019
muscle cell fate specification GO:0042694 1 0.019
negative regulation of hormone metabolic process GO:0032351 4 0.019
blood coagulation GO:0007596 76 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
calcium ion transport into cytosol GO:0060402 48 0.019
limb morphogenesis GO:0035108 149 0.019
protein localization to plasma membrane GO:0072659 57 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.019
canonical wnt signaling pathway GO:0060070 130 0.018
rho protein signal transduction GO:0007266 32 0.018
regulation of protein binding GO:0043393 60 0.018
response to metal ion GO:0010038 47 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
amine metabolic process GO:0009308 45 0.018
positive regulation of interleukin 8 production GO:0032757 2 0.018
negative regulation of wnt signaling pathway GO:0030178 73 0.018
stem cell differentiation GO:0048863 268 0.018
cartilage development GO:0051216 140 0.018
regulation of feeding behavior GO:0060259 3 0.018
sensory perception of sound GO:0007605 97 0.018
mitotic cytokinesis GO:0000281 4 0.018
positive regulation of cell projection organization GO:0031346 95 0.018
ras protein signal transduction GO:0007265 77 0.018
nuclear division GO:0000280 158 0.018
establishment of organelle localization GO:0051656 122 0.018
glycoprotein metabolic process GO:0009100 116 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
male gamete generation GO:0048232 285 0.018
regulation of protein processing GO:0070613 96 0.018
Mouse
eating behavior GO:0042755 15 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
cell junction organization GO:0034330 77 0.018
transforming growth factor beta2 production GO:0032906 2 0.018
regulation of skeletal muscle adaptation GO:0014733 12 0.018
appendage development GO:0048736 166 0.018
negative regulation of growth GO:0045926 99 0.018
skeletal system morphogenesis GO:0048705 203 0.017
positive regulation of endocytosis GO:0045807 42 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
positive regulation of vasoconstriction GO:0045907 4 0.017
dna metabolic process GO:0006259 303 0.017
regulation of cellular component size GO:0032535 121 0.017
peripheral nervous system neuron axonogenesis GO:0048936 3 0.017
sodium ion transport GO:0006814 73 0.017
oviduct development GO:0060066 3 0.017
coagulation GO:0050817 78 0.017
respiratory system development GO:0060541 190 0.017
establishment of tissue polarity GO:0007164 28 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
synapse organization GO:0050808 125 0.017
autonomic nervous system development GO:0048483 43 0.017
organelle fission GO:0048285 170 0.017
establishment of protein localization to membrane GO:0090150 54 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.017
intermediate filament bundle assembly GO:0045110 3 0.017
cytoskeleton dependent intracellular transport GO:0030705 50 0.017
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
regulation of cellular component biogenesis GO:0044087 181 0.016
positive regulation of potassium ion transport GO:0043268 3 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
amino acid transport GO:0006865 61 0.016
sinoatrial node cell differentiation GO:0060921 3 0.016
renal sodium ion transport GO:0003096 2 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
regulation of protein kinase activity GO:0045859 232 0.016
Mouse
fibroblast growth factor production GO:0090269 4 0.016
regulation of blood pressure GO:0008217 93 0.016
negative regulation of endopeptidase activity GO:0010951 44 0.016
Mouse
lipid localization GO:0010876 126 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of inward rectifier potassium channel activity GO:1901979 1 0.016
sensory organ morphogenesis GO:0090596 242 0.016
Mouse
organic acid transport GO:0015849 101 0.016
response to fibroblast growth factor GO:0071774 47 0.016
regulation of protein depolymerization GO:1901879 26 0.016
regulation of hydrolase activity GO:0051336 246 0.016
Mouse
establishment of anatomical structure orientation GO:0048560 1 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.016
neural tube formation GO:0001841 108 0.016
cellular homeostasis GO:0019725 240 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
regulation of interleukin 1 beta production GO:0032651 25 0.016
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.016
outer medullary collecting duct development GO:0072060 1 0.016
regulation of axon extension GO:0030516 43 0.016
schwann cell proliferation GO:0014010 2 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
ventricular cardiac muscle tissue development GO:0003229 38 0.016
establishment of protein localization to plasma membrane GO:0090002 34 0.016
positive regulation of cell substrate adhesion GO:0010811 47 0.016
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.016
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.015
regulation of potassium ion transmembrane transport GO:1901379 11 0.015
positive regulation of potassium ion transmembrane transport GO:1901381 3 0.015
regulation of secretion by cell GO:1903530 249 0.015
oxygen homeostasis GO:0032364 2 0.015
mitochondrial transport GO:0006839 36 0.015
establishment of planar polarity GO:0001736 28 0.015
regulation of cell activation GO:0050865 289 0.015
calcium ion transmembrane transport GO:0070588 85 0.015
positive regulation of cell adhesion GO:0045785 80 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.015
male gonad development GO:0008584 88 0.015
regulation of interleukin 8 secretion GO:2000482 2 0.015
striated muscle adaptation GO:0014888 26 0.015
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.015
nuclear import GO:0051170 95 0.015
regulation of the force of heart contraction GO:0002026 17 0.015
lipid biosynthetic process GO:0008610 179 0.015
transmission of nerve impulse GO:0019226 76 0.015
glucose metabolic process GO:0006006 92 0.015
peptidyl serine modification GO:0018209 83 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
regulation of sodium ion transport GO:0002028 29 0.015
learning or memory GO:0007611 148 0.015
chondrocyte differentiation GO:0002062 72 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.015
Mouse
gtp catabolic process GO:0006184 143 0.015
positive regulation of transmembrane transport GO:0034764 29 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
Mouse
microtubule based movement GO:0007018 84 0.014
regulation of atpase activity GO:0043462 9 0.014
lung induction GO:0060492 3 0.014
cell communication involved in cardiac conduction GO:0086065 9 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
protein complex disassembly GO:0043241 40 0.014
positive regulation of protein transport GO:0051222 93 0.014
organic acid biosynthetic process GO:0016053 86 0.014
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.014
response to transforming growth factor beta GO:0071559 88 0.014
regulation of map kinase activity GO:0043405 120 0.014
regulation of neuron projection development GO:0010975 169 0.014
regulation of membrane repolarization GO:0060306 7 0.014
blood vessel morphogenesis GO:0048514 285 0.014
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.014
macromolecule glycosylation GO:0043413 55 0.014
positive regulation of muscle cell differentiation GO:0051149 39 0.014
epidermis development GO:0008544 187 0.014
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.014
kidney rudiment formation GO:0072003 3 0.014
single organism cell adhesion GO:0098602 156 0.014
regulation of cell growth GO:0001558 91 0.014
Mouse
kidney development GO:0001822 213 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014

Hspb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.907
disease of anatomical entity DOID:7 0 0.907
musculoskeletal system disease DOID:17 0 0.907
muscle tissue disease DOID:66 0 0.820
myopathy DOID:423 0 0.743
heart disease DOID:114 0 0.552
cardiomyopathy DOID:0050700 0 0.552
cardiovascular system disease DOID:1287 0 0.552
intrinsic cardiomyopathy DOID:0060036 0 0.256
hypertrophic cardiomyopathy DOID:11984 0 0.202
dilated cardiomyopathy DOID:12930 0 0.072
muscular dystrophy DOID:9884 0 0.056
nervous system disease DOID:863 0 0.049
neuromuscular disease DOID:440 0 0.032
neuropathy DOID:870 0 0.032
sensory system disease DOID:0050155 0 0.015