Mus musculus

152 known processes

Hspb1

heat shock protein 1

(Aliases: 27kDa,Hsp25)

Hspb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
apoptotic signaling pathway GO:0097190 306 0.432
camera type eye development GO:0043010 266 0.431
Mouse
actin filament organization GO:0007015 113 0.354
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.300
Mouse
mitochondrion organization GO:0007005 134 0.293
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.293
actin cytoskeleton organization GO:0030036 220 0.282
Mouse
spermatogenesis GO:0007283 284 0.271
lens development in camera type eye GO:0002088 62 0.261
Mouse
regulation of transferase activity GO:0051338 263 0.232
actin filament based movement GO:0030048 23 0.227
regulation of protein maturation GO:1903317 96 0.218
Mouse
epithelial cell development GO:0002064 159 0.216
Mouse
tubulin complex biogenesis GO:0072668 2 0.215
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.210
dna metabolic process GO:0006259 303 0.203
lens morphogenesis in camera type eye GO:0002089 24 0.200
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.192
circulatory system process GO:0003013 197 0.185
regulation of hydrolase activity GO:0051336 246 0.182
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.179
positive regulation of transferase activity GO:0051347 167 0.173
microtubule based process GO:0007017 236 0.172
Mouse
organelle assembly GO:0070925 177 0.171
actomyosin structure organization GO:0031032 56 0.169
negative regulation of protein metabolic process GO:0051248 282 0.156
positive regulation of protein kinase activity GO:0045860 144 0.152
protein maturation GO:0051604 176 0.150
Mouse
muscle cell differentiation GO:0042692 261 0.148
skeletal muscle organ development GO:0060538 163 0.146
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.144
regulation of protein kinase activity GO:0045859 232 0.144
male gamete generation GO:0048232 285 0.143
regulation of kinase activity GO:0043549 249 0.142
negative regulation of molecular function GO:0044092 258 0.141
cardiac muscle cell differentiation GO:0055007 69 0.140
regulation of endopeptidase activity GO:0052548 89 0.137
Mouse
negative regulation of protein processing GO:0010955 79 0.137
Mouse
myofibril assembly GO:0030239 34 0.135
positive regulation of glial cell proliferation GO:0060252 4 0.124
muscle tissue development GO:0060537 308 0.123
response to radiation GO:0009314 165 0.119
Mouse
actin mediated cell contraction GO:0070252 15 0.113
microtubule cytoskeleton organization GO:0000226 157 0.102
response to light stimulus GO:0009416 135 0.102
Mouse
tubulin complex assembly GO:0007021 2 0.101
Mouse
muscle cell development GO:0055001 133 0.097
extrinsic apoptotic signaling pathway GO:0097191 126 0.096
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.096
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.095
embryonic organ morphogenesis GO:0048562 276 0.093
Mouse
cellular protein complex assembly GO:0043623 116 0.092
Mouse
response to uv a GO:0070141 1 0.092
Mouse
regulation of cell motility GO:2000145 236 0.091
Human
negative regulation of apoptotic signaling pathway GO:2001234 104 0.091
ventricular cardiac muscle cell action potential GO:0086005 4 0.090
positive regulation of growth GO:0045927 104 0.088
Mouse
sensory organ morphogenesis GO:0090596 242 0.088
Mouse
peripheral nervous system axon regeneration GO:0014012 2 0.084
negative regulation of cellular component organization GO:0051129 194 0.084
carbohydrate metabolic process GO:0005975 230 0.084
striated muscle cell development GO:0055002 125 0.083
regulation of cell migration GO:0030334 219 0.082
Human
striated muscle tissue development GO:0014706 293 0.081
germ cell development GO:0007281 185 0.081
regulation of organelle organization GO:0033043 289 0.080
chemotaxis GO:0006935 247 0.080
Human
positive regulation of protein modification process GO:0031401 299 0.079
Mouse
response to decreased oxygen levels GO:0036293 59 0.079
Mouse Fly
cellular ketone metabolic process GO:0042180 84 0.078
regulation of cellular amino acid metabolic process GO:0006521 5 0.078
negative regulation of intracellular signal transduction GO:1902532 167 0.077
intrinsic apoptotic signaling pathway GO:0097193 132 0.073
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.073
positive regulation of mapk cascade GO:0043410 170 0.071
cellular response to dna damage stimulus GO:0006974 207 0.071
negative regulation of response to oxidative stress GO:1902883 10 0.071
cellular amino acid metabolic process GO:0006520 103 0.071
negative regulation of phosphorylation GO:0042326 166 0.071
ribose phosphate metabolic process GO:0019693 291 0.070
cell type specific apoptotic process GO:0097285 268 0.070
cell junction organization GO:0034330 77 0.070
response to uv GO:0009411 44 0.070
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.070
regulation of protein localization GO:0032880 231 0.070
cell substrate adhesion GO:0031589 130 0.069
regulation of angiogenesis GO:0045765 81 0.068
Human
placenta development GO:0001890 140 0.066
cellular lipid metabolic process GO:0044255 323 0.064
positive regulation of kinase activity GO:0033674 155 0.063
ribonucleoside metabolic process GO:0009119 245 0.062
purine containing compound metabolic process GO:0072521 311 0.059
protein processing GO:0016485 163 0.059
Mouse
t cell activation GO:0042110 289 0.059
mitotic cell cycle GO:0000278 195 0.059
axonogenesis GO:0007409 274 0.058
response to reactive oxygen species GO:0000302 56 0.058
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.058
negative regulation of protein maturation GO:1903318 79 0.058
Mouse
regulation of protein processing GO:0070613 96 0.058
Mouse
photoreceptor cell differentiation GO:0046530 52 0.057
cell growth GO:0016049 130 0.056
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.056
epidermis development GO:0008544 187 0.055
oxidation reduction process GO:0055114 342 0.055
wnt signaling pathway GO:0016055 188 0.055
modification dependent macromolecule catabolic process GO:0043632 133 0.054
response to temperature stimulus GO:0009266 55 0.054
Zebrafish Fly
i kappab kinase nf kappab signaling GO:0007249 85 0.054
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.053
regulation of cellular component size GO:0032535 121 0.053
regulation of cell cycle process GO:0010564 160 0.052
blood circulation GO:0008015 195 0.052
organic cyclic compound catabolic process GO:1901361 295 0.052
negative regulation of transferase activity GO:0051348 85 0.051
macromolecule catabolic process GO:0009057 281 0.051
protein localization to membrane GO:0072657 108 0.051
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.051
regulation of cytokine production GO:0001817 266 0.050
membrane organization GO:0061024 245 0.050
striated muscle myosin thick filament assembly GO:0071688 1 0.049
negative regulation of peptidase activity GO:0010466 46 0.047
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.046
Mouse
wound healing GO:0042060 157 0.046
Human
negative regulation of hydrolase activity GO:0051346 71 0.045
Mouse
respiratory tube development GO:0030323 167 0.045
intermediate filament cytoskeleton organization GO:0045104 26 0.044
myeloid cell differentiation GO:0030099 233 0.044
heart contraction GO:0060047 93 0.044
blood vessel morphogenesis GO:0048514 285 0.044
Human
peptidyl amino acid modification GO:0018193 336 0.043
cell adhesion GO:0007155 329 0.043
Human
heart process GO:0003015 94 0.043
sarcomere organization GO:0045214 24 0.043
response to fibroblast growth factor GO:0071774 47 0.042
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.042
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.042
muscle system process GO:0003012 141 0.041
Zebrafish
regulation of peptidase activity GO:0052547 96 0.041
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.040
cytokine production GO:0001816 319 0.040
protein catabolic process GO:0030163 221 0.040
epithelial cell proliferation GO:0050673 174 0.040
ribonucleotide metabolic process GO:0009259 291 0.040
regulation of cellular response to growth factor stimulus GO:0090287 82 0.039
cell matrix adhesion GO:0007160 68 0.039
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.038
response to growth factor GO:0070848 198 0.038
Human
regulation of proteolysis GO:0030162 164 0.038
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.038
regulation of lipid metabolic process GO:0019216 118 0.038
monocarboxylic acid metabolic process GO:0032787 191 0.037
oocyte construction GO:0007308 2 0.037
embryonic placenta development GO:0001892 98 0.037
skeletal myofibril assembly GO:0014866 4 0.037
multicellular organism growth GO:0035264 161 0.037
positive regulation of cell death GO:0010942 224 0.037
regulation of establishment of protein localization GO:0070201 181 0.037
immune effector process GO:0002252 321 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.036
cell recognition GO:0008037 83 0.036
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.036
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.036
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.035
negative regulation of protein modification process GO:0031400 163 0.035
regulation of cellular component biogenesis GO:0044087 181 0.034
negative regulation of cell cycle GO:0045786 123 0.034
intermediate filament organization GO:0045109 15 0.034
response to oxygen levels GO:0070482 62 0.034
Mouse Fly
negative regulation of cell proliferation GO:0008285 296 0.034
striated muscle contraction GO:0006941 45 0.034
response to insulin GO:0032868 100 0.034
multicellular organismal homeostasis GO:0048871 164 0.034
Human
negative regulation of oxidative stress induced cell death GO:1903202 9 0.033
regulation of defense response GO:0031347 233 0.033
cellular protein catabolic process GO:0044257 155 0.033
response to heat GO:0009408 27 0.033
Zebrafish
ubiquitin dependent protein catabolic process GO:0006511 129 0.033
protein localization to plasma membrane GO:0072659 57 0.032
single organism cell adhesion GO:0098602 156 0.032
Human
ameboidal type cell migration GO:0001667 128 0.032
Human
myeloid leukocyte differentiation GO:0002573 119 0.032
phospholipid metabolic process GO:0006644 87 0.032
transmembrane transport GO:0055085 412 0.032
cardiac muscle tissue development GO:0048738 130 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.031
lung development GO:0030324 164 0.031
locomotory behavior GO:0007626 195 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
eye photoreceptor cell differentiation GO:0001754 41 0.031
spermatid differentiation GO:0048515 115 0.031
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.031
nucleotide metabolic process GO:0009117 332 0.031
gonad development GO:0008406 141 0.031
cytokine mediated signaling pathway GO:0019221 115 0.031
spermatid development GO:0007286 108 0.031
regulation of myeloid cell differentiation GO:0045637 96 0.030
purine nucleoside catabolic process GO:0006152 205 0.030
ossification GO:0001503 216 0.030
stem cell differentiation GO:0048863 268 0.030
integrin mediated signaling pathway GO:0007229 27 0.030
respiratory system development GO:0060541 190 0.030
multi multicellular organism process GO:0044706 109 0.030
cardiac muscle cell contraction GO:0086003 7 0.030
regulation of system process GO:0044057 200 0.030
Zebrafish
regulation of purine nucleotide metabolic process GO:1900542 169 0.029
reactive oxygen species biosynthetic process GO:1903409 8 0.029
cellularization GO:0007349 1 0.029
positive regulation of interleukin 1 beta production GO:0032731 16 0.029
peptidyl tyrosine modification GO:0018212 145 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
regulation of mapk cascade GO:0043408 248 0.029
development of primary sexual characteristics GO:0045137 143 0.029
glycosyl compound catabolic process GO:1901658 206 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
cellular response to peptide hormone stimulus GO:0071375 92 0.028
mapk cascade GO:0000165 281 0.028
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.028
myosin filament assembly GO:0031034 2 0.028
regulation of vasculature development GO:1901342 88 0.028
Human
defense response to other organism GO:0098542 197 0.027
tumor necrosis factor production GO:0032640 50 0.027
regulation of cell cycle GO:0051726 281 0.027
actin filament bundle assembly GO:0051017 40 0.027
response to hypoxia GO:0001666 58 0.027
Mouse Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
lymphocyte proliferation GO:0046651 164 0.027
cellular response to oxidative stress GO:0034599 76 0.027
cell cell junction organization GO:0045216 72 0.026
molting cycle GO:0042303 90 0.026
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.026
mesoderm development GO:0007498 100 0.026
regulation of multi organism process GO:0043900 111 0.026
reactive nitrogen species metabolic process GO:2001057 0 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.025
eye photoreceptor cell development GO:0042462 31 0.025
chromatin organization GO:0006325 206 0.025
mitotic cell cycle process GO:1903047 159 0.025
gland development GO:0048732 330 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
carbohydrate homeostasis GO:0033500 128 0.025
regulation of cell size GO:0008361 72 0.025
positive regulation of cell development GO:0010720 237 0.025
leukocyte proliferation GO:0070661 172 0.025
metanephric glomerular endothelium development GO:0072264 1 0.025
epithelium migration GO:0090132 63 0.025
Human
regulation of vesicle mediated transport GO:0060627 139 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
regionalization GO:0003002 337 0.024
negative regulation of kinase activity GO:0033673 81 0.024
dna repair GO:0006281 107 0.024
compound eye development GO:0048749 1 0.024
skeletal muscle thin filament assembly GO:0030240 2 0.024
aromatic compound catabolic process GO:0019439 286 0.024
osteoclast differentiation GO:0030316 62 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
acetylcholine transport GO:0015870 2 0.024
negative regulation of endopeptidase activity GO:0010951 44 0.024
Mouse
regulation of chromosome organization GO:0033044 83 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
Human
positive regulation of nervous system development GO:0051962 221 0.024
positive regulation of cytokine production GO:0001819 174 0.024
photoreceptor cell development GO:0042461 40 0.024
endocytosis GO:0006897 168 0.023
nucleoside catabolic process GO:0009164 206 0.023
adult behavior GO:0030534 135 0.023
t cell proliferation GO:0042098 120 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
protein ubiquitination GO:0016567 171 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
cell junction assembly GO:0034329 52 0.023
homeostasis of number of cells GO:0048872 210 0.023
regulation of cell adhesion GO:0030155 154 0.023
negative regulation of immune system process GO:0002683 209 0.023
early endosome to late endosome transport GO:0045022 2 0.023
acetate ester transport GO:1901374 2 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
adherens junction organization GO:0034332 28 0.023
regulation of cell activation GO:0050865 289 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
protein autophosphorylation GO:0046777 61 0.022
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 9 0.022
regulation of tumor necrosis factor production GO:0032680 49 0.022
cytoskeleton dependent intracellular transport GO:0030705 50 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
regulation of protein transport GO:0051223 163 0.021
cellular amine metabolic process GO:0044106 44 0.021
negative regulation of organelle organization GO:0010639 90 0.021
regulation of ion transmembrane transport GO:0034765 119 0.021
regulation of systemic arterial blood pressure GO:0003073 61 0.021
kidney development GO:0001822 213 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
oocyte axis specification GO:0007309 2 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
cellular response to peptide GO:1901653 92 0.021
skeletal system development GO:0001501 356 0.021
regulation of endocytosis GO:0030100 69 0.021
regulation of body fluid levels GO:0050878 162 0.021
Human
negative regulation of neuron apoptotic process GO:0043524 92 0.020
positive regulation of immune effector process GO:0002699 107 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
gene silencing by rna GO:0031047 19 0.020
regulation of myeloid leukocyte differentiation GO:0002761 58 0.020
fat cell differentiation GO:0045444 160 0.020
nitrogen compound transport GO:0071705 271 0.020
morphogenesis of a branching epithelium GO:0061138 193 0.020
positive regulation of cytokine biosynthetic process GO:0042108 40 0.020
endomembrane system organization GO:0010256 147 0.020
response to oxidative stress GO:0006979 123 0.020
response to hydrogen peroxide GO:0042542 32 0.020
Mouse
glycosyl compound metabolic process GO:1901657 246 0.020
female gamete generation GO:0007292 74 0.020
epithelial to mesenchymal transition GO:0001837 47 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
cellular response to hormone stimulus GO:0032870 150 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
microtubule based transport GO:0010970 50 0.019
hemostasis GO:0007599 78 0.019
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
anatomical structure homeostasis GO:0060249 145 0.019
Human
regulation of response to wounding GO:1903034 189 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
cellular homeostasis GO:0019725 240 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
positive regulation of cell cycle GO:0045787 92 0.019
axon cargo transport GO:0008088 33 0.019
embryonic camera type eye development GO:0031076 36 0.019
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.018
Human
response to extracellular stimulus GO:0009991 127 0.018
embryonic eye morphogenesis GO:0048048 29 0.018
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.018
meiotic cell cycle process GO:1903046 77 0.018
dna replication GO:0006260 52 0.018
mesenchymal cell differentiation GO:0048762 107 0.018
sa node cell action potential GO:0086015 4 0.018
leukocyte differentiation GO:0002521 342 0.018
regulation of feeding behavior GO:0060259 3 0.018
stem cell development GO:0048864 219 0.018
cellular response to x ray GO:0071481 2 0.018
heterocycle catabolic process GO:0046700 280 0.018
tissue migration GO:0090130 68 0.018
Human
negative regulation of proteolysis GO:0045861 74 0.018
Mouse
protein oligomerization GO:0051259 67 0.018
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
establishment of protein localization to membrane GO:0090150 54 0.018
neurotransmitter transport GO:0006836 76 0.018
intracellular protein transport GO:0006886 204 0.018
mesenchymal cell development GO:0014031 93 0.018
cardiocyte differentiation GO:0035051 87 0.018
negative regulation of defense response GO:0031348 77 0.018
immunoglobulin production GO:0002377 73 0.018
myotube differentiation GO:0014902 105 0.018
cell maturation GO:0048469 127 0.017
leukocyte mediated immunity GO:0002443 174 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
hexose metabolic process GO:0019318 98 0.017
lipid biosynthetic process GO:0008610 179 0.017
cytokine metabolic process GO:0042107 71 0.017
response to peptide hormone GO:0043434 127 0.017
regulation of response to oxidative stress GO:1902882 19 0.017
monosaccharide metabolic process GO:0005996 106 0.017
meiosis i GO:0007127 60 0.017
rna processing GO:0006396 105 0.017
nucleoside metabolic process GO:0009116 246 0.017
skeletal muscle myosin thick filament assembly GO:0030241 1 0.017
regulation of protein kinase b signaling GO:0051896 56 0.017
nucleotide catabolic process GO:0009166 217 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
cellular response to lipid GO:0071396 145 0.017
axon guidance GO:0007411 141 0.017
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.016
coagulation GO:0050817 78 0.016
Human
organelle fission GO:0048285 170 0.016
muscle cell proliferation GO:0033002 52 0.016
tube formation GO:0035148 140 0.016
negative regulation of fat cell differentiation GO:0045599 36 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
regulation of anatomical structure size GO:0090066 178 0.016
Zebrafish
apoptotic process involved in morphogenesis GO:0060561 25 0.016
Mouse
protein modification by small protein conjugation GO:0032446 187 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
response to organonitrogen compound GO:0010243 246 0.016
developmental maturation GO:0021700 193 0.016
sensory perception of light stimulus GO:0050953 54 0.016
substrate dependent cell migration cell attachment to substrate GO:0006931 2 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
detection of abiotic stimulus GO:0009582 60 0.016
connective tissue development GO:0061448 179 0.016
neurotransmitter secretion GO:0007269 62 0.016
cardiac muscle cell development GO:0055013 39 0.016
regulation of cellular catabolic process GO:0031329 242 0.015
epithelial cell migration GO:0010631 63 0.015
Human
regulation of nucleoside metabolic process GO:0009118 130 0.015
rna interference GO:0016246 2 0.015
regulation of intracellular transport GO:0032386 159 0.015
positive regulation of organelle organization GO:0010638 128 0.015
innate immune response GO:0045087 157 0.015
organophosphate catabolic process GO:0046434 232 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
positive regulation of proteolysis GO:0045862 85 0.015
response to organic cyclic compound GO:0014070 198 0.015
negative regulation of neuron death GO:1901215 98 0.015
hair follicle morphogenesis GO:0031069 29 0.015
sensory perception GO:0007600 245 0.015
protein localization to organelle GO:0033365 185 0.015
fatty acid metabolic process GO:0006631 121 0.015
posttranscriptional gene silencing GO:0016441 10 0.015
cytoplasmic transport GO:0016482 234 0.015
angiogenesis GO:0001525 201 0.015
Human
adherens junction assembly GO:0034333 22 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
myosin filament organization GO:0031033 3 0.015
endothelial cell migration GO:0043542 44 0.015
Human
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.015
myeloid leukocyte activation GO:0002274 83 0.014
regulation of ossification GO:0030278 112 0.014
translation GO:0006412 93 0.014
glucose metabolic process GO:0006006 92 0.014
apical constriction GO:0003383 4 0.014
negative regulation of multi organism process GO:0043901 68 0.014
ear development GO:0043583 200 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
meiotic cell cycle GO:0051321 122 0.014
metanephric mesangial cell differentiation GO:0072209 1 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
myotube cell development GO:0014904 60 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
midgut development GO:0007494 4 0.014
visual perception GO:0007601 52 0.014
purine containing compound catabolic process GO:0072523 213 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
Human
cell death in response to oxidative stress GO:0036473 24 0.014
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
regulation of heart contraction GO:0008016 77 0.014
cardiac muscle contraction GO:0060048 32 0.014
response to inorganic substance GO:0010035 96 0.014
Mouse
organophosphate biosynthetic process GO:0090407 122 0.014
cellular response to extracellular stimulus GO:0031668 81 0.014
atp metabolic process GO:0046034 75 0.014
cytokine biosynthetic process GO:0042089 68 0.014
urogenital system development GO:0001655 261 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
renal system process GO:0003014 48 0.013
establishment of protein localization to plasma membrane GO:0090002 34 0.013
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
mesenchyme development GO:0060485 152 0.013
glucose homeostasis GO:0042593 128 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
syncytium formation by plasma membrane fusion GO:0000768 42 0.013
skeletal muscle fiber development GO:0048741 58 0.013
neuron apoptotic process GO:0051402 142 0.013
regulation of response to biotic stimulus GO:0002831 38 0.013
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.013
primitive erythrocyte differentiation GO:0060319 3 0.013
intracellular mrna localization GO:0008298 4 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
amine metabolic process GO:0009308 45 0.013
gene silencing GO:0016458 38 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
extracellular structure organization GO:0043062 148 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
digestive system development GO:0055123 200 0.013
intermediate filament based process GO:0045103 27 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
macromolecular complex disassembly GO:0032984 43 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013

Hspb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.051
disease of anatomical entity DOID:7 0 0.051
Human
cardiovascular system disease DOID:1287 0 0.051
muscular disease DOID:0080000 0 0.044
musculoskeletal system disease DOID:17 0 0.044
myopathy DOID:423 0 0.044
cardiomyopathy DOID:0050700 0 0.044
muscle tissue disease DOID:66 0 0.044
nervous system disease DOID:863 0 0.020
Human
sensory system disease DOID:0050155 0 0.018