Mus musculus

0 known processes

Pdp1

pyruvate dehyrogenase phosphatase catalytic subunit 1

(Aliases: Ppm2c,Gm1024)

Pdp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.087
regulation of cellular amino acid metabolic process GO:0006521 5 0.075
cellular amino acid metabolic process GO:0006520 103 0.073
cellular ketone metabolic process GO:0042180 84 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.061
macromolecule catabolic process GO:0009057 281 0.061
protein ubiquitination GO:0016567 171 0.060
amine metabolic process GO:0009308 45 0.059
protein modification by small protein conjugation or removal GO:0070647 207 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.056
nucleotide metabolic process GO:0009117 332 0.055
nucleoside phosphate metabolic process GO:0006753 338 0.055
protein catabolic process GO:0030163 221 0.052
negative regulation of protein metabolic process GO:0051248 282 0.048
ribonucleoside metabolic process GO:0009119 245 0.045
heterocycle catabolic process GO:0046700 280 0.044
nucleoside metabolic process GO:0009116 246 0.044
protein modification by small protein conjugation GO:0032446 187 0.043
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
glycosyl compound metabolic process GO:1901657 246 0.042
modification dependent macromolecule catabolic process GO:0043632 133 0.042
purine containing compound metabolic process GO:0072521 311 0.041
regulation of hydrolase activity GO:0051336 246 0.039
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
purine nucleotide metabolic process GO:0006163 302 0.037
cellular macromolecule catabolic process GO:0044265 206 0.036
transmembrane transport GO:0055085 412 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
aromatic compound catabolic process GO:0019439 286 0.035
ribose phosphate metabolic process GO:0019693 291 0.035
organic cyclic compound catabolic process GO:1901361 295 0.034
negative regulation of molecular function GO:0044092 258 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
cation transport GO:0006812 399 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
ribonucleoside catabolic process GO:0042454 206 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
positive regulation of protein modification process GO:0031401 299 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
male gamete generation GO:0048232 285 0.030
regulation of transferase activity GO:0051338 263 0.030
synaptic transmission GO:0007268 329 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.030
regulation of apoptotic signaling pathway GO:2001233 197 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
apoptotic signaling pathway GO:0097190 306 0.029
regulation of organelle organization GO:0033043 289 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.028
cation transmembrane transport GO:0098655 266 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
regulation of neuron differentiation GO:0045664 281 0.027
organophosphate catabolic process GO:0046434 232 0.027
neuron death GO:0070997 154 0.027
cytoplasmic transport GO:0016482 234 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
membrane organization GO:0061024 245 0.027
cellular protein catabolic process GO:0044257 155 0.027
response to organonitrogen compound GO:0010243 246 0.026
regulation of kinase activity GO:0043549 249 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
muscle cell differentiation GO:0042692 261 0.026
nitrogen compound transport GO:0071705 271 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
ion transmembrane transport GO:0034220 361 0.026
nucleoside catabolic process GO:0009164 206 0.026
response to peptide hormone GO:0043434 127 0.026
glycosyl compound catabolic process GO:1901658 206 0.025
oxidation reduction process GO:0055114 342 0.025
positive regulation of apoptotic process GO:0043065 217 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
cell type specific apoptotic process GO:0097285 268 0.025
nucleotide catabolic process GO:0009166 217 0.025
peptidyl amino acid modification GO:0018193 336 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
regulation of cellular catabolic process GO:0031329 242 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
spermatogenesis GO:0007283 284 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.024
striated muscle tissue development GO:0014706 293 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
positive regulation of cell death GO:0010942 224 0.023
homeostasis of number of cells GO:0048872 210 0.023
regulation of cell projection organization GO:0031344 206 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
cellular lipid metabolic process GO:0044255 323 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
intracellular protein transport GO:0006886 204 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
protein processing GO:0016485 163 0.022
response to growth factor GO:0070848 198 0.022
lymphocyte differentiation GO:0030098 242 0.022
carbohydrate metabolic process GO:0005975 230 0.022
regulation of secretion GO:0051046 274 0.022
endomembrane system organization GO:0010256 147 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
purine containing compound catabolic process GO:0072523 213 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
regulation of neuron apoptotic process GO:0043523 122 0.021
ras protein signal transduction GO:0007265 77 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
camera type eye development GO:0043010 266 0.021
negative regulation of protein modification process GO:0031400 163 0.021
regulation of ion transport GO:0043269 215 0.020
fat cell differentiation GO:0045444 160 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
cognition GO:0050890 149 0.020
regulation of protein localization GO:0032880 231 0.020
guanosine containing compound metabolic process GO:1901068 144 0.020
positive regulation of nervous system development GO:0051962 221 0.020
proteasomal protein catabolic process GO:0010498 98 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
protein maturation GO:0051604 176 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
forebrain development GO:0030900 302 0.020
regulation of secretion by cell GO:1903530 249 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
sensory perception GO:0007600 245 0.019
protein localization to organelle GO:0033365 185 0.019
cellular homeostasis GO:0019725 240 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
cellular chemical homeostasis GO:0055082 215 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
tube formation GO:0035148 140 0.018
leukocyte differentiation GO:0002521 342 0.018
organelle localization GO:0051640 179 0.018
organelle fission GO:0048285 170 0.018
neuron apoptotic process GO:0051402 142 0.018
microtubule based process GO:0007017 236 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
learning or memory GO:0007611 148 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
establishment of organelle localization GO:0051656 122 0.017
positive regulation of cell development GO:0010720 237 0.017
regulation of hormone levels GO:0010817 211 0.017
skeletal muscle organ development GO:0060538 163 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
regulation of neuron projection development GO:0010975 169 0.017
regulation of cell motility GO:2000145 236 0.017
nucleoside monophosphate metabolic process GO:0009123 85 0.017
gland development GO:0048732 330 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
regulation of membrane potential GO:0042391 192 0.017
macromolecule methylation GO:0043414 120 0.017
protein polymerization GO:0051258 57 0.016
compound eye development GO:0048749 1 0.016
dephosphorylation GO:0016311 129 0.016
Human Fly
adult behavior GO:0030534 135 0.016
maintenance of location GO:0051235 89 0.016
dna metabolic process GO:0006259 303 0.016
axonogenesis GO:0007409 274 0.016
cellular ion homeostasis GO:0006873 165 0.016
blood vessel morphogenesis GO:0048514 285 0.016
respiratory system development GO:0060541 190 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
t cell activation GO:0042110 289 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
telencephalon development GO:0021537 186 0.016
mapk cascade GO:0000165 281 0.016
rho protein signal transduction GO:0007266 32 0.016
glycoprotein metabolic process GO:0009100 116 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
mitotic cell cycle GO:0000278 195 0.016
fertilization GO:0009566 127 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
cellular protein complex assembly GO:0043623 116 0.016
connective tissue development GO:0061448 179 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
mitotic cell cycle process GO:1903047 159 0.016
multicellular organismal signaling GO:0035637 91 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
negative regulation of organelle organization GO:0010639 90 0.016
sensory organ morphogenesis GO:0090596 242 0.016
response to radiation GO:0009314 165 0.016
gtp metabolic process GO:0046039 144 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of protein kinase activity GO:0045859 232 0.015
positive regulation of organelle organization GO:0010638 128 0.015
germ cell development GO:0007281 185 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
small molecule biosynthetic process GO:0044283 132 0.015
chemotaxis GO:0006935 247 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
transmission of nerve impulse GO:0019226 76 0.015
muscle tissue development GO:0060537 308 0.015
adaptive immune response GO:0002250 155 0.015
protein localization to membrane GO:0072657 108 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
immune effector process GO:0002252 321 0.015
cation homeostasis GO:0055080 212 0.015
divalent inorganic cation transport GO:0072511 178 0.015
neural tube development GO:0021915 160 0.015
regulation of neuron death GO:1901214 134 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
response to organic cyclic compound GO:0014070 198 0.015
nuclear division GO:0000280 158 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
atp metabolic process GO:0046034 75 0.015
myeloid cell differentiation GO:0030099 233 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
establishment of vesicle localization GO:0051650 81 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of voltage gated calcium channel activity GO:1901385 4 0.014
synapse organization GO:0050808 125 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
dendrite development GO:0016358 115 0.014
regulation of cell activation GO:0050865 289 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
regulation of cell migration GO:0030334 219 0.014
t cell differentiation GO:0030217 174 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
regulation of cell cycle GO:0051726 281 0.014
regulation of t cell activation GO:0050863 170 0.014
regionalization GO:0003002 337 0.014
male genitalia morphogenesis GO:0048808 4 0.014
neuronal action potential GO:0019228 54 0.014
multi multicellular organism process GO:0044706 109 0.014
muscle cell development GO:0055001 133 0.014
male anatomical structure morphogenesis GO:0090598 4 0.013
wnt signaling pathway GO:0016055 188 0.013
divalent metal ion transport GO:0070838 172 0.013
action potential GO:0001508 78 0.013
multicellular organism growth GO:0035264 161 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
response to lipopolysaccharide GO:0032496 128 0.013
mitochondrion organization GO:0007005 134 0.013
regulation of homeostatic process GO:0032844 182 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
carbohydrate homeostasis GO:0033500 128 0.013
meiotic nuclear division GO:0007126 115 0.013
regulation of intracellular transport GO:0032386 159 0.013
regulation of transmembrane transport GO:0034762 128 0.013
carboxylic acid transport GO:0046942 100 0.013
cell division GO:0051301 120 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
glucose homeostasis GO:0042593 128 0.013
respiratory tube development GO:0030323 167 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of protein processing GO:0070613 96 0.013
amide transport GO:0042886 138 0.013
substantia nigra development GO:0021762 2 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
regulation of protein maturation GO:1903317 96 0.013
cell adhesion GO:0007155 329 0.013
regulation of leukocyte differentiation GO:1902105 159 0.012
glycerolipid metabolic process GO:0046486 122 0.012
renal system development GO:0072001 225 0.012
regulation of feeding behavior GO:0060259 3 0.012
regulation of protein catabolic process GO:0042176 108 0.012
organic anion transport GO:0015711 137 0.012
methylation GO:0032259 134 0.012
kidney development GO:0001822 213 0.012
b cell activation GO:0042113 161 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of proteolysis GO:0030162 164 0.012
negative regulation of neuron death GO:1901215 98 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
hormone secretion GO:0046879 128 0.012
actin cytoskeleton organization GO:0030036 220 0.012
lung development GO:0030324 164 0.012
muscle system process GO:0003012 141 0.012
innate immune response GO:0045087 157 0.012
developmental maturation GO:0021700 193 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
striated muscle cell development GO:0055002 125 0.012
metal ion homeostasis GO:0055065 189 0.012
protein glycosylation GO:0006486 55 0.012
regulation of cytokine production GO:0001817 266 0.012
cellular response to lipid GO:0071396 145 0.012
skeletal system development GO:0001501 356 0.012
regulation of multi organism process GO:0043900 111 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
sulfur compound metabolic process GO:0006790 100 0.012
locomotory behavior GO:0007626 195 0.012
organic acid biosynthetic process GO:0016053 86 0.012
plasma membrane organization GO:0007009 90 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
gtp catabolic process GO:0006184 143 0.012
stem cell differentiation GO:0048863 268 0.012
lipid biosynthetic process GO:0008610 179 0.012
spermatid differentiation GO:0048515 115 0.012
angiogenesis GO:0001525 201 0.012
inflammatory response GO:0006954 244 0.012
cytokine production GO:0001816 319 0.012
response to inorganic substance GO:0010035 96 0.012
establishment of protein localization to membrane GO:0090150 54 0.012
peptide transport GO:0015833 133 0.011
fatty acid metabolic process GO:0006631 121 0.011
glycosylation GO:0070085 62 0.011
protein targeting GO:0006605 143 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
digestive system development GO:0055123 200 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
ossification GO:0001503 216 0.011
small molecule catabolic process GO:0044282 71 0.011
response to peptide GO:1901652 136 0.011
anatomical structure homeostasis GO:0060249 145 0.011
urogenital system development GO:0001655 261 0.011
spermatid development GO:0007286 108 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
regulation of binding GO:0051098 111 0.011
peptidyl serine modification GO:0018209 83 0.011
negative regulation of transferase activity GO:0051348 85 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
response to light stimulus GO:0009416 135 0.011
regulation of cellular response to growth factor stimulus GO:0090287 82 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
vesicle localization GO:0051648 86 0.011
myotube differentiation GO:0014902 105 0.011
positive regulation of transferase activity GO:0051347 167 0.011
epidermis development GO:0008544 187 0.011
regulation of mapk cascade GO:0043408 248 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
female gamete generation GO:0007292 74 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
cell growth GO:0016049 130 0.011
muscle fiber development GO:0048747 76 0.011
organic acid transport GO:0015849 101 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
single fertilization GO:0007338 82 0.011
regulation of response to wounding GO:1903034 189 0.011
regulation of adaptive immune response GO:0002819 90 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.010
rna splicing GO:0008380 54 0.010
rhythmic process GO:0048511 174 0.010
rna processing GO:0006396 105 0.010
negative regulation of kinase activity GO:0033673 81 0.010
sequestering of calcium ion GO:0051208 18 0.010
epithelial tube formation GO:0072175 130 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
protein localization to nucleus GO:0034504 121 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
meiotic cell cycle GO:0051321 122 0.010
nuclear transport GO:0051169 139 0.010
anion transport GO:0006820 177 0.010
rac protein signal transduction GO:0016601 13 0.010
smoothened signaling pathway GO:0007224 105 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
endocytosis GO:0006897 168 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
peptide hormone secretion GO:0030072 109 0.010

Pdp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
central nervous system disease DOID:331 0 0.016
musculoskeletal system disease DOID:17 0 0.015
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
muscle tissue disease DOID:66 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011