Mus musculus

0 known processes

Leng8

leukocyte receptor cluster (LRC) member 8

(Aliases: AW049671)

Leng8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.148
myotube differentiation GO:0014902 105 0.108
macromolecule methylation GO:0043414 120 0.098
stem cell maintenance GO:0019827 130 0.094
dna metabolic process GO:0006259 303 0.073
cellular macromolecule catabolic process GO:0044265 206 0.065
purine containing compound metabolic process GO:0072521 311 0.061
mrna metabolic process GO:0016071 84 0.058
protein methylation GO:0006479 81 0.054
regulation of translation GO:0006417 71 0.054
translation GO:0006412 93 0.054
histone methylation GO:0016571 71 0.054
cellular protein catabolic process GO:0044257 155 0.053
methylation GO:0032259 134 0.053
purine nucleotide metabolic process GO:0006163 302 0.053
monosaccharide metabolic process GO:0005996 106 0.053
aromatic compound catabolic process GO:0019439 286 0.050
purine ribonucleotide metabolic process GO:0009150 290 0.048
membrane fusion GO:0061025 38 0.048
nucleoside phosphate metabolic process GO:0006753 338 0.048
nucleoside metabolic process GO:0009116 246 0.047
regulation of nucleotide metabolic process GO:0006140 169 0.047
membrane organization GO:0061024 245 0.045
regulation of purine nucleotide catabolic process GO:0033121 122 0.045
positive regulation of nucleoside metabolic process GO:0045979 91 0.044
organelle localization GO:0051640 179 0.043
regulation of cellular catabolic process GO:0031329 242 0.043
organic cyclic compound catabolic process GO:1901361 295 0.042
lipid homeostasis GO:0055088 63 0.040
microtubule based process GO:0007017 236 0.040
gene silencing GO:0016458 38 0.040
lung development GO:0030324 164 0.038
regulation of histone methylation GO:0031060 30 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
cation transport GO:0006812 399 0.038
sequestering of calcium ion GO:0051208 18 0.037
purine nucleoside catabolic process GO:0006152 205 0.036
positive regulation of histone h3 k27 methylation GO:0061087 4 0.036
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 6 0.036
striated muscle tissue development GO:0014706 293 0.035
stem cell development GO:0048864 219 0.035
muscle tissue development GO:0060537 308 0.035
positive regulation of protein modification process GO:0031401 299 0.034
respiratory tube development GO:0030323 167 0.034
histone lysine methylation GO:0034968 50 0.034
protein alkylation GO:0008213 81 0.034
regulation of reactive oxygen species metabolic process GO:2000377 40 0.034
nucleoside catabolic process GO:0009164 206 0.034
small gtpase mediated signal transduction GO:0007264 97 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
cellular nitrogen compound catabolic process GO:0044270 280 0.033
regulation of nucleotide catabolic process GO:0030811 122 0.032
regulation of actin nucleation GO:0051125 4 0.032
respiratory system development GO:0060541 190 0.032
nucleotide catabolic process GO:0009166 217 0.032
regulation of organelle organization GO:0033043 289 0.031
leukocyte differentiation GO:0002521 342 0.031
polysaccharide metabolic process GO:0005976 39 0.031
heterocycle catabolic process GO:0046700 280 0.031
regulation of transporter activity GO:0032409 57 0.031
limb morphogenesis GO:0035108 149 0.031
positive regulation of beta amyloid clearance GO:1900223 1 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.030
positive regulation of cellular catabolic process GO:0031331 148 0.029
response to insulin GO:0032868 100 0.029
organic hydroxy compound metabolic process GO:1901615 203 0.029
modification dependent protein catabolic process GO:0019941 133 0.029
regulation of intracellular transport GO:0032386 159 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
organophosphate catabolic process GO:0046434 232 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.028
positive regulation of transferase activity GO:0051347 167 0.028
cellular response to dna damage stimulus GO:0006974 207 0.028
positive regulation of gtpase activity GO:0043547 85 0.028
positive regulation of cell death GO:0010942 224 0.027
regionalization GO:0003002 337 0.027
macromolecule catabolic process GO:0009057 281 0.027
regulation of striated muscle cell differentiation GO:0051153 81 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
histone h3 k4 trimethylation GO:0080182 5 0.027
regulation of membrane potential GO:0042391 192 0.026
regulation of cellular response to stress GO:0080135 159 0.026
appendage morphogenesis GO:0035107 149 0.026
epithelial tube morphogenesis GO:0060562 303 0.026
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
divalent inorganic cation homeostasis GO:0072507 138 0.025
stem cell differentiation GO:0048863 268 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
regulation of myotube differentiation GO:0010830 62 0.025
gtp metabolic process GO:0046039 144 0.025
regulation of secretion by cell GO:1903530 249 0.025
carbohydrate metabolic process GO:0005975 230 0.025
regulation of cell cycle GO:0051726 281 0.025
glucose metabolic process GO:0006006 92 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
gtp catabolic process GO:0006184 143 0.024
gland development GO:0048732 330 0.024
guanosine containing compound metabolic process GO:1901068 144 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
establishment of organelle localization GO:0051656 122 0.023
cellularization GO:0007349 1 0.023
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
vesicle localization GO:0051648 86 0.023
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.023
response to peptide hormone GO:0043434 127 0.023
organic acid biosynthetic process GO:0016053 86 0.023
proteasomal protein catabolic process GO:0010498 98 0.023
sequestering of metal ion GO:0051238 19 0.022
nitrogen compound transport GO:0071705 271 0.022
lipid biosynthetic process GO:0008610 179 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
phosphatidylethanolamine metabolic process GO:0046337 2 0.022
cellular ion homeostasis GO:0006873 165 0.022
regulation of neuron differentiation GO:0045664 281 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
actin cytoskeleton organization GO:0030036 220 0.022
regulation of mrna metabolic process GO:1903311 43 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
rhythmic process GO:0048511 174 0.022
lymphocyte differentiation GO:0030098 242 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
peptidyl amino acid modification GO:0018193 336 0.021
cellular response to peptide GO:1901653 92 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
positive regulation of gtp catabolic process GO:0033126 85 0.021
rna processing GO:0006396 105 0.021
neural tube closure GO:0001843 90 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
negative regulation of cation channel activity GO:2001258 1 0.021
developmental maturation GO:0021700 193 0.021
regulation of ion transport GO:0043269 215 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.021
protein ubiquitination GO:0016567 171 0.021
multicellular organism growth GO:0035264 161 0.021
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.020
hexose metabolic process GO:0019318 98 0.020
cell type specific apoptotic process GO:0097285 268 0.020
regulation of response to drug GO:2001023 2 0.020
single fertilization GO:0007338 82 0.020
carbohydrate biosynthetic process GO:0016051 74 0.020
development of primary sexual characteristics GO:0045137 143 0.020
organic acid transport GO:0015849 101 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
wnt signaling pathway GO:0016055 188 0.020
dna alkylation GO:0006305 43 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
male gamete generation GO:0048232 285 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
defecation GO:0030421 1 0.019
tube formation GO:0035148 140 0.019
regulation of secretion GO:0051046 274 0.019
protein maturation GO:0051604 176 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
cellular chemical homeostasis GO:0055082 215 0.018
maintenance of location GO:0051235 89 0.018
cell fate commitment GO:0045165 210 0.018
multi multicellular organism process GO:0044706 109 0.018
protein localization to organelle GO:0033365 185 0.018
cation transmembrane transport GO:0098655 266 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
regulation of transferase activity GO:0051338 263 0.018
response to organonitrogen compound GO:0010243 246 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
skeletal system development GO:0001501 356 0.018
regulation of ral gtpase activity GO:0032315 4 0.018
neuron death GO:0070997 154 0.018
positive regulation of kinase activity GO:0033674 155 0.017
t cell differentiation GO:0030217 174 0.017
fertilization GO:0009566 127 0.017
circadian regulation of gene expression GO:0032922 48 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
regulation of myeloid cell differentiation GO:0045637 96 0.017
glucose homeostasis GO:0042593 128 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
ras protein signal transduction GO:0007265 77 0.017
actin filament organization GO:0007015 113 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
sensory perception of mechanical stimulus GO:0050954 107 0.017
organelle fission GO:0048285 170 0.017
heart contraction GO:0060047 93 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
cellular response to acid chemical GO:0071229 68 0.017
exocytosis GO:0006887 121 0.017
ascending thin limb development GO:0072021 2 0.017
response to acid chemical GO:0001101 111 0.016
t cell activation GO:0042110 289 0.016
protein processing GO:0016485 163 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
positive regulation of organelle organization GO:0010638 128 0.016
mitotic cell cycle GO:0000278 195 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
homeostasis of number of cells GO:0048872 210 0.016
neuroblast fate determination GO:0007400 1 0.016
protein catabolic process GO:0030163 221 0.016
positive regulation of dna templated transcription elongation GO:0032786 2 0.016
regulation of establishment of planar polarity GO:0090175 28 0.016
blood circulation GO:0008015 195 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
alcohol metabolic process GO:0006066 116 0.016
reactive oxygen species metabolic process GO:0072593 84 0.015
organic anion transport GO:0015711 137 0.015
protein localization to plasma membrane GO:0072659 57 0.015
regulation of hydrolase activity GO:0051336 246 0.015
establishment or maintenance of cell polarity GO:0007163 86 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.015
dna modification GO:0006304 50 0.015
gliogenesis GO:0042063 141 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
endodermal cell fate specification GO:0001714 4 0.015
protein localization to membrane GO:0072657 108 0.015
calcium ion dependent exocytosis GO:0017156 35 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
oxidation reduction process GO:0055114 342 0.015
cellular response to lipid GO:0071396 145 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of muscle tissue development GO:1901861 97 0.015
regulation of reproductive process GO:2000241 66 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
circulatory system process GO:0003013 197 0.014
endoderm development GO:0007492 45 0.014
gonad development GO:0008406 141 0.014
sensory perception GO:0007600 245 0.014
defense response to other organism GO:0098542 197 0.014
synaptic transmission GO:0007268 329 0.014
ion transmembrane transport GO:0034220 361 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
response to peptide GO:1901652 136 0.014
regulation of cellular response to insulin stimulus GO:1900076 30 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
actin filament polymerization GO:0030041 44 0.014
viral gene expression GO:0019080 3 0.014
striated muscle contraction GO:0006941 45 0.014
histone h4 k16 acetylation GO:0043984 3 0.014
rho protein signal transduction GO:0007266 32 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
small molecule biosynthetic process GO:0044283 132 0.014
cellular amine metabolic process GO:0044106 44 0.014
cellular response to insulin stimulus GO:0032869 78 0.014
negative regulation of organelle organization GO:0010639 90 0.014
synaptic vesicle transport GO:0048489 57 0.014
mrna processing GO:0006397 63 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
ovarian follicle development GO:0001541 40 0.014
neural precursor cell proliferation GO:0061351 121 0.013
cardiac cell fate specification GO:0060912 2 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of calcium ion transmembrane transport GO:1903169 20 0.013
metanephric ascending thin limb development GO:0072218 2 0.013
intracellular mrna localization GO:0008298 4 0.013
negative regulation of glycoprotein metabolic process GO:1903019 3 0.013
establishment of protein localization to membrane GO:0090150 54 0.013
regulation of cellular component size GO:0032535 121 0.013
detection of nodal flow GO:0003127 2 0.013
regulation of binding GO:0051098 111 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
intracellular lipid transport GO:0032365 3 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
intracellular protein transport GO:0006886 204 0.013
cellular response to fluid shear stress GO:0071498 4 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
regulation of insulin receptor signaling pathway GO:0046626 21 0.013
liver development GO:0001889 66 0.013
peptide transport GO:0015833 133 0.013
photoreceptor cell morphogenesis GO:0008594 3 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
renal system development GO:0072001 225 0.013
myeloid cell homeostasis GO:0002262 114 0.013
organic hydroxy compound transport GO:0015850 93 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
sensory perception of sound GO:0007605 97 0.013
plasma membrane organization GO:0007009 90 0.013
skeletal system morphogenesis GO:0048705 203 0.012
regulation of chromosome organization GO:0033044 83 0.012
anion transport GO:0006820 177 0.012
regulation of protein transport GO:0051223 163 0.012
dna templated transcription termination GO:0006353 4 0.012
regulation of carbohydrate biosynthetic process GO:0043255 40 0.012
cell adhesion GO:0007155 329 0.012
pharynx development GO:0060465 1 0.012
nucleotide metabolic process GO:0009117 332 0.012
cellular protein complex assembly GO:0043623 116 0.012
peptide secretion GO:0002790 114 0.012
germ cell development GO:0007281 185 0.012
dephosphorylation GO:0016311 129 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
regulation of metal ion transport GO:0010959 106 0.012
regulation of chromatin modification GO:1903308 57 0.012
cholesterol transport GO:0030301 38 0.012
regulation of cell projection organization GO:0031344 206 0.012
peptidyl serine modification GO:0018209 83 0.012
purine containing compound catabolic process GO:0072523 213 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
regulation of multi organism process GO:0043900 111 0.011
positive regulation of thymocyte migration GO:2000412 2 0.011
regulation of phospholipase a2 activity GO:0032429 3 0.011
forebrain development GO:0030900 302 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
anatomical structure homeostasis GO:0060249 145 0.011
metencephalon development GO:0022037 89 0.011
regulation of anatomical structure size GO:0090066 178 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
regulation of protein kinase activity GO:0045859 232 0.011
kidney development GO:0001822 213 0.011
chromatin organization GO:0006325 206 0.011
blastocyst development GO:0001824 80 0.011
amine metabolic process GO:0009308 45 0.011
regulation of microtubule based process GO:0032886 52 0.011
regulation of homeostatic process GO:0032844 182 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
cellular ketone metabolic process GO:0042180 84 0.011
carboxylic acid transport GO:0046942 100 0.011
adult behavior GO:0030534 135 0.011
negative regulation of leukocyte differentiation GO:1902106 51 0.011
chemotaxis GO:0006935 247 0.011
calcium ion transport GO:0006816 159 0.011
negative regulation of translation GO:0017148 22 0.011
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.011
regulation of kinase activity GO:0043549 249 0.011
negative regulation of glycoprotein biosynthetic process GO:0010561 3 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
primary neural tube formation GO:0014020 95 0.011
insulin receptor signaling pathway GO:0008286 49 0.011
regulation of cell adhesion GO:0030155 154 0.011
peptidyl lysine methylation GO:0018022 29 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
endocrine system development GO:0035270 98 0.011
hindbrain development GO:0030902 128 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
actin filament based movement GO:0030048 23 0.011
neurotransmitter secretion GO:0007269 62 0.011
regulation of blood circulation GO:1903522 93 0.011
regulation of protein maturation GO:1903317 96 0.011
alpha beta t cell differentiation GO:0046632 69 0.011
negative regulation of triglyceride biosynthetic process GO:0010868 2 0.010
nuclear import GO:0051170 95 0.010
response to oxygen radical GO:0000305 16 0.010
somitogenesis GO:0001756 69 0.010
negative regulation of molecular function GO:0044092 258 0.010
peptidyl serine phosphorylation GO:0018105 74 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
regulation of neuron death GO:1901214 134 0.010
regulation of defense response to bacterium GO:1900424 3 0.010
mrna splicing via spliceosome GO:0000398 43 0.010
regulation of protein localization GO:0032880 231 0.010
rna splicing GO:0008380 54 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
circadian rhythm GO:0007623 114 0.010
monosaccharide biosynthetic process GO:0046364 44 0.010
mitochondrion organization GO:0007005 134 0.010
synaptic vesicle localization GO:0097479 59 0.010

Leng8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.015
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.014
neurodegenerative disease DOID:1289 0 0.011
bone remodeling disease DOID:0080005 0 0.010
bone disease DOID:0080001 0 0.010
osteopetrosis DOID:13533 0 0.010
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010
osteosclerosis DOID:4254 0 0.010