Mus musculus

24 known processes

Penk

preproenkephalin

(Aliases: PPA,ENK,Penk1,AI326464)

Penk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.132
amine metabolic process GO:0009308 45 0.105
cation transport GO:0006812 399 0.092
transmembrane transport GO:0055085 412 0.087
cellular response to growth factor stimulus GO:0071363 197 0.085
nucleoside phosphate metabolic process GO:0006753 338 0.083
lipid biosynthetic process GO:0008610 179 0.083
spermatogenesis GO:0007283 284 0.082
nucleotide metabolic process GO:0009117 332 0.080
muscle system process GO:0003012 141 0.079
purine containing compound metabolic process GO:0072521 311 0.079
cellular lipid metabolic process GO:0044255 323 0.075
cellular amine metabolic process GO:0044106 44 0.074
chemotaxis GO:0006935 247 0.074
muscle tissue development GO:0060537 308 0.073
regulation of system process GO:0044057 200 0.072
negative regulation of molecular function GO:0044092 258 0.070
cell adhesion GO:0007155 329 0.069
regulation of homeostatic process GO:0032844 182 0.068
male gamete generation GO:0048232 285 0.065
circulatory system process GO:0003013 197 0.064
ossification GO:0001503 216 0.064
skeletal system development GO:0001501 356 0.064
positive regulation of cellular amine metabolic process GO:0033240 5 0.064
metal ion homeostasis GO:0055065 189 0.062
organic cyclic compound catabolic process GO:1901361 295 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
regulation of hydrolase activity GO:0051336 246 0.059
regulation of cellular ketone metabolic process GO:0010565 66 0.059
cellular ketone metabolic process GO:0042180 84 0.058
striated muscle tissue development GO:0014706 293 0.054
respiratory system development GO:0060541 190 0.054
organophosphate catabolic process GO:0046434 232 0.053
nucleoside phosphate catabolic process GO:1901292 222 0.053
blood vessel morphogenesis GO:0048514 285 0.053
ribose phosphate metabolic process GO:0019693 291 0.052
cation homeostasis GO:0055080 212 0.051
inorganic ion transmembrane transport GO:0098660 234 0.051
regulation of cellular amine metabolic process GO:0033238 20 0.051
ribonucleotide metabolic process GO:0009259 291 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
ribonucleoside metabolic process GO:0009119 245 0.049
regulation of neuron differentiation GO:0045664 281 0.049
positive regulation of cell death GO:0010942 224 0.048
monocarboxylic acid metabolic process GO:0032787 191 0.048
purine ribonucleoside catabolic process GO:0046130 205 0.048
locomotory behavior GO:0007626 195 0.046
cellular chemical homeostasis GO:0055082 215 0.045
purine nucleotide metabolic process GO:0006163 302 0.044
positive regulation of programmed cell death GO:0043068 218 0.044
glycosyl compound catabolic process GO:1901658 206 0.044
branching morphogenesis of an epithelial tube GO:0048754 159 0.044
cell type specific apoptotic process GO:0097285 268 0.043
negative regulation of cell proliferation GO:0008285 296 0.043
regulation of nucleotide metabolic process GO:0006140 169 0.043
axonogenesis GO:0007409 274 0.042
regulation of hormone levels GO:0010817 211 0.042
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.042
heterocycle catabolic process GO:0046700 280 0.041
blood circulation GO:0008015 195 0.041
renal system development GO:0072001 225 0.041
negative regulation of protein metabolic process GO:0051248 282 0.040
purine ribonucleotide metabolic process GO:0009150 290 0.040
action potential GO:0001508 78 0.039
ribonucleoside triphosphate metabolic process GO:0009199 220 0.039
epithelial tube morphogenesis GO:0060562 303 0.039
cellular ion homeostasis GO:0006873 165 0.039
aromatic compound catabolic process GO:0019439 286 0.039
regulation of anatomical structure size GO:0090066 178 0.038
purine nucleoside metabolic process GO:0042278 241 0.038
kidney development GO:0001822 213 0.038
regulation of membrane potential GO:0042391 192 0.038
negative regulation of hormone biosynthetic process GO:0032353 4 0.037
limb morphogenesis GO:0035108 149 0.037
purine nucleotide catabolic process GO:0006195 211 0.037
germ cell development GO:0007281 185 0.037
nucleoside triphosphate metabolic process GO:0009141 230 0.036
lung development GO:0030324 164 0.036
nucleoside metabolic process GO:0009116 246 0.036
muscle cell development GO:0055001 133 0.036
limb development GO:0060173 166 0.036
positive regulation of protein phosphorylation GO:0001934 242 0.036
developmental growth involved in morphogenesis GO:0060560 138 0.036
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
skeletal system morphogenesis GO:0048705 203 0.035
g protein coupled receptor signaling pathway GO:0007186 243 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.034
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
peptidyl amino acid modification GO:0018193 336 0.033
multicellular organism growth GO:0035264 161 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
bone morphogenesis GO:0060349 78 0.033
morphogenesis of a branching epithelium GO:0061138 193 0.032
wnt signaling pathway GO:0016055 188 0.032
divalent inorganic cation homeostasis GO:0072507 138 0.032
carbohydrate metabolic process GO:0005975 230 0.032
regulation of mapk cascade GO:0043408 248 0.032
purine nucleoside catabolic process GO:0006152 205 0.031
membrane organization GO:0061024 245 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
inorganic cation transmembrane transport GO:0098662 207 0.031
reactive oxygen species metabolic process GO:0072593 84 0.031
protein maturation GO:0051604 176 0.030
calcium ion homeostasis GO:0055074 127 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.030
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
angiogenesis GO:0001525 201 0.030
regulation of lymphocyte activation GO:0051249 240 0.030
positive regulation of cell development GO:0010720 237 0.030
maintenance of location GO:0051235 89 0.030
embryonic limb morphogenesis GO:0030326 126 0.030
peptidyl serine modification GO:0018209 83 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
respiratory tube development GO:0030323 167 0.029
epithelial cell proliferation GO:0050673 174 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
organ growth GO:0035265 117 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.028
sensory organ morphogenesis GO:0090596 242 0.028
regulation of epithelial cell proliferation GO:0050678 141 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
connective tissue development GO:0061448 179 0.028
apoptotic signaling pathway GO:0097190 306 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
response to growth factor GO:0070848 198 0.028
ureteric bud development GO:0001657 94 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
regulation of cell substrate adhesion GO:0010810 73 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
protein processing GO:0016485 163 0.027
organophosphate biosynthetic process GO:0090407 122 0.027
cellular homeostasis GO:0019725 240 0.027
skeletal muscle organ development GO:0060538 163 0.027
embryonic placenta development GO:0001892 98 0.027
positive regulation of protein modification process GO:0031401 299 0.027
negative regulation of protein maturation GO:1903318 79 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
muscle contraction GO:0006936 101 0.026
embryonic organ morphogenesis GO:0048562 276 0.026
divalent metal ion transport GO:0070838 172 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.026
cation transmembrane transport GO:0098655 266 0.026
morphogenesis of a branching structure GO:0001763 203 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
camera type eye development GO:0043010 266 0.026
immune effector process GO:0002252 321 0.026
multicellular organismal signaling GO:0035637 91 0.025
sulfur compound metabolic process GO:0006790 100 0.025
lymphocyte differentiation GO:0030098 242 0.025
positive regulation of growth GO:0045927 104 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
tube formation GO:0035148 140 0.025
nucleotide catabolic process GO:0009166 217 0.025
cellular divalent inorganic cation homeostasis GO:0072503 127 0.025
regulation of blood pressure GO:0008217 93 0.025
ras protein signal transduction GO:0007265 77 0.025
small molecule biosynthetic process GO:0044283 132 0.025
morphogenesis of embryonic epithelium GO:0016331 159 0.025
spermatid development GO:0007286 108 0.025
negative regulation of protein processing GO:0010955 79 0.025
compound eye development GO:0048749 1 0.025
inflammatory response GO:0006954 244 0.025
regulation of intracellular transport GO:0032386 159 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
endomembrane system organization GO:0010256 147 0.024
digestive tract development GO:0048565 190 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
t cell activation GO:0042110 289 0.024
regulation of cellular response to stress GO:0080135 159 0.024
appendage morphogenesis GO:0035107 149 0.024
regulation of protein localization GO:0032880 231 0.024
rhythmic process GO:0048511 174 0.024
spermatid differentiation GO:0048515 115 0.024
cartilage development GO:0051216 140 0.024
ion transmembrane transport GO:0034220 361 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
single organism cell adhesion GO:0098602 156 0.024
fat cell differentiation GO:0045444 160 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
regulation of tube size GO:0035150 57 0.024
regulation of purine nucleotide catabolic process GO:0033121 122 0.023
developmental maturation GO:0021700 193 0.023
organelle localization GO:0051640 179 0.023
cell growth GO:0016049 130 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
regulation of ion transport GO:0043269 215 0.023
forebrain development GO:0030900 302 0.023
negative regulation of hormone metabolic process GO:0032351 4 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
urogenital system development GO:0001655 261 0.023
regulation of eosinophil migration GO:2000416 2 0.022
nucleoside catabolic process GO:0009164 206 0.022
purine containing compound catabolic process GO:0072523 213 0.022
midgut development GO:0007494 4 0.022
regulation of cell activation GO:0050865 289 0.022
regulation of actin filament based process GO:0032970 99 0.022
negative regulation of proteolysis GO:0045861 74 0.022
bone development GO:0060348 120 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
cellular response to lipid GO:0071396 145 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
response to transforming growth factor beta GO:0071559 88 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
positive regulation of neuron differentiation GO:0045666 141 0.022
organic acid biosynthetic process GO:0016053 86 0.021
cardiac muscle tissue development GO:0048738 130 0.021
response to organic cyclic compound GO:0014070 198 0.021
hindbrain development GO:0030902 128 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
hormone metabolic process GO:0042445 86 0.021
regulation of peptidase activity GO:0052547 96 0.021
muscle cell differentiation GO:0042692 261 0.021
extracellular structure organization GO:0043062 148 0.021
response to inorganic substance GO:0010035 96 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
regulation of transferase activity GO:0051338 263 0.021
adult behavior GO:0030534 135 0.021
regulation of cell migration GO:0030334 219 0.021
response to oxidative stress GO:0006979 123 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
positive regulation of cell adhesion GO:0045785 80 0.020
heart process GO:0003015 94 0.020
digestive system development GO:0055123 200 0.020
regulation of secretion by cell GO:1903530 249 0.020
nuclear division GO:0000280 158 0.020
response to organonitrogen compound GO:0010243 246 0.020
regulation of vasculature development GO:1901342 88 0.020
nitrogen compound transport GO:0071705 271 0.020
t cell differentiation GO:0030217 174 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
leukocyte migration GO:0050900 124 0.020
regulation of cell motility GO:2000145 236 0.020
regulation of proteolysis GO:0030162 164 0.020
sequestering of calcium ion GO:0051208 18 0.020
regulation of voltage gated calcium channel activity GO:1901385 4 0.020
sensory perception GO:0007600 245 0.020
cellular protein complex assembly GO:0043623 116 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
regulation of secretion GO:0051046 274 0.020
regulation of muscle contraction GO:0006937 49 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
myotube differentiation GO:0014902 105 0.020
multicellular organismal response to stress GO:0033555 62 0.019
alcohol metabolic process GO:0006066 116 0.019
regulation of muscle system process GO:0090257 80 0.019
hexose metabolic process GO:0019318 98 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
regulation of ion homeostasis GO:2000021 64 0.019
sequestering of metal ion GO:0051238 19 0.019
smoothened signaling pathway GO:0007224 105 0.019
negative regulation of protein modification process GO:0031400 163 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.019
glycoprotein metabolic process GO:0009100 116 0.019
striated muscle cell development GO:0055002 125 0.019
regulation of ossification GO:0030278 112 0.019
synaptic transmission GO:0007268 329 0.019
response to reactive oxygen species GO:0000302 56 0.019
positive regulation of proteolysis GO:0045862 85 0.019
kidney epithelium development GO:0072073 121 0.019
embryonic appendage morphogenesis GO:0035113 126 0.019
negative regulation of cell development GO:0010721 169 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
organelle fission GO:0048285 170 0.019
mesonephric epithelium development GO:0072163 94 0.019
dephosphorylation GO:0016311 129 0.019
cardiac muscle cell differentiation GO:0055007 69 0.019
regulation of cell projection organization GO:0031344 206 0.018
regionalization GO:0003002 337 0.018
regulation of metal ion transport GO:0010959 106 0.018
transmission of nerve impulse GO:0019226 76 0.018
heart morphogenesis GO:0003007 178 0.018
cytokine production GO:0001816 319 0.018
male meiosis GO:0007140 37 0.018
cell chemotaxis GO:0060326 81 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
meiotic nuclear division GO:0007126 115 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
rap protein signal transduction GO:0032486 3 0.018
mesoderm development GO:0007498 100 0.018
negative regulation of nervous system development GO:0051961 156 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
adult locomotory behavior GO:0008344 91 0.018
cytoplasmic transport GO:0016482 234 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
response to radiation GO:0009314 165 0.017
positive regulation of protein transport GO:0051222 93 0.017
fertilization GO:0009566 127 0.017
regulation of t cell activation GO:0050863 170 0.017
regulation of cell cycle GO:0051726 281 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
stem cell proliferation GO:0072089 117 0.017
vascular process in circulatory system GO:0003018 62 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
fatty acid metabolic process GO:0006631 121 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
actin filament organization GO:0007015 113 0.017
macromolecule catabolic process GO:0009057 281 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
regulation of organelle organization GO:0033043 289 0.016
rho protein signal transduction GO:0007266 32 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
response to extracellular stimulus GO:0009991 127 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
microtubule based process GO:0007017 236 0.016
anion transport GO:0006820 177 0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.016
carbohydrate biosynthetic process GO:0016051 74 0.016
regulation of striated muscle cell differentiation GO:0051153 81 0.016
negative regulation of peptidase activity GO:0010466 46 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
neural precursor cell proliferation GO:0061351 121 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.016
defecation GO:0030421 1 0.016
establishment of organelle localization GO:0051656 122 0.016
mesonephric tubule development GO:0072164 94 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
gtp metabolic process GO:0046039 144 0.016
mapk cascade GO:0000165 281 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
fatty acid biosynthetic process GO:0006633 41 0.016
negative regulation of immune system process GO:0002683 209 0.016
response to light stimulus GO:0009416 135 0.016
regulation of circadian sleep wake cycle GO:0042749 3 0.016
appendage development GO:0048736 166 0.016
muscle fiber development GO:0048747 76 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
positive regulation of nervous system development GO:0051962 221 0.016
regulation of angiogenesis GO:0045765 81 0.016
regulation of protein processing GO:0070613 96 0.016
mitotic cell cycle process GO:1903047 159 0.015
meiotic cell cycle GO:0051321 122 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
oxidation reduction process GO:0055114 342 0.015
muscle adaptation GO:0043500 39 0.015
regulation of multi organism process GO:0043900 111 0.015
actin filament based movement GO:0030048 23 0.015
protein glycosylation GO:0006486 55 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
metencephalon development GO:0022037 89 0.015
mitotic cytokinesis GO:0000281 4 0.015
adaptive immune response GO:0002250 155 0.015
regulation of cell adhesion GO:0030155 154 0.015
leukocyte mediated immunity GO:0002443 174 0.015
glycerolipid metabolic process GO:0046486 122 0.015
negative regulation of neuron differentiation GO:0045665 101 0.015
regulation of calcium ion transport GO:0051924 69 0.015
regulation of protein maturation GO:1903317 96 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
cell maturation GO:0048469 127 0.015
calcium ion transport GO:0006816 159 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
plasma membrane organization GO:0007009 90 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
leukocyte differentiation GO:0002521 342 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
stem cell differentiation GO:0048863 268 0.015
cell substrate adhesion GO:0031589 130 0.015
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.015
regulation of defense response GO:0031347 233 0.015
regulation of receptor activity GO:0010469 41 0.014
intracellular protein transport GO:0006886 204 0.014
lymphocyte proliferation GO:0046651 164 0.014
chromatin organization GO:0006325 206 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
metanephros development GO:0001656 79 0.014
membrane tubulation GO:0097320 4 0.014
bmp signaling pathway GO:0030509 93 0.014
regulation of cell growth GO:0001558 91 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.014
regulation of monocyte chemotaxis GO:0090025 3 0.014
placenta development GO:0001890 140 0.014
glycerolipid biosynthetic process GO:0045017 50 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
response to steroid hormone GO:0048545 56 0.014
mitotic cell cycle GO:0000278 195 0.014
calcium ion transmembrane transport GO:0070588 85 0.014
cytokinetic process GO:0032506 2 0.014
gliogenesis GO:0042063 141 0.014
regulation of cytokine production GO:0001817 266 0.014
exocytosis GO:0006887 121 0.014
actin cytoskeleton organization GO:0030036 220 0.014
cardiac chamber development GO:0003205 108 0.014
negative regulation of endopeptidase activity GO:0010951 44 0.014
cellular response to inorganic substance GO:0071241 37 0.014
protein catabolic process GO:0030163 221 0.014
actin filament polymerization GO:0030041 44 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
lateral line system development GO:0048925 1 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
divalent inorganic cation transport GO:0072511 178 0.014
regulation of map kinase activity GO:0043405 120 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
i kappab kinase nf kappab signaling GO:0007249 85 0.013
endocytosis GO:0006897 168 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
aminoglycan metabolic process GO:0006022 34 0.013
membrane lipid metabolic process GO:0006643 53 0.013
regulation of response to wounding GO:1903034 189 0.013
regulation of angiotensin levels in blood GO:0002002 4 0.013
heart contraction GO:0060047 93 0.013
neuromuscular process GO:0050905 99 0.013
actomyosin structure organization GO:0031032 56 0.013
regulation of kinase activity GO:0043549 249 0.013
renal sodium excretion GO:0035812 3 0.013
regulation of neuron death GO:1901214 134 0.013
spinal cord development GO:0021510 81 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
regulation of binding GO:0051098 111 0.013
positive regulation of cell activation GO:0050867 158 0.013
striated muscle contraction GO:0006941 45 0.013
vesicle localization GO:0051648 86 0.013
dna metabolic process GO:0006259 303 0.013
organelle assembly GO:0070925 177 0.013
kidney morphogenesis GO:0060993 83 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
peptidyl serine phosphorylation GO:0018105 74 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
regulation of muscle tissue development GO:1901861 97 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
behavioral response to nutrient GO:0051780 1 0.013
defense response to bacterium GO:0042742 119 0.013
response to peptide GO:1901652 136 0.013
neuron apoptotic process GO:0051402 142 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
steroid metabolic process GO:0008202 119 0.013
cofactor metabolic process GO:0051186 80 0.013
reflex GO:0060004 22 0.013
protein modification by small protein conjugation GO:0032446 187 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
response to drug GO:0042493 75 0.012
tube closure GO:0060606 91 0.012
regulation of cell cycle process GO:0010564 160 0.012
axon guidance GO:0007411 141 0.012
ameboidal type cell migration GO:0001667 128 0.012
digestive tract morphogenesis GO:0048546 147 0.012
epithelial tube formation GO:0072175 130 0.012
neuron projection extension GO:1990138 64 0.012
nephron development GO:0072006 109 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
positive regulation of organelle organization GO:0010638 128 0.012
response to peptide hormone GO:0043434 127 0.012
membrane lipid biosynthetic process GO:0046467 32 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
regulation of endocytosis GO:0030100 69 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
cell matrix adhesion GO:0007160 68 0.012
cell fate commitment GO:0045165 210 0.012
response to corticosterone GO:0051412 1 0.012
macromolecule glycosylation GO:0043413 55 0.012
positive regulation of monocyte chemotaxis GO:0090026 2 0.012
regulation of rho gtpase activity GO:0032319 58 0.012
female gamete generation GO:0007292 74 0.012
neuron death GO:0070997 154 0.012
protein localization to organelle GO:0033365 185 0.012
regulation of angiotensin metabolic process GO:0060177 4 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
positive regulation of mitotic cell cycle GO:0045931 41 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
regulation of osteoblast differentiation GO:0045667 67 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
carboxylic acid transport GO:0046942 100 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
neural tube development GO:0021915 160 0.012
regulation of transmembrane transport GO:0034762 128 0.012
interleukin 8 production GO:0032637 4 0.012
glucose metabolic process GO:0006006 92 0.012

Penk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
muscle tissue disease DOID:66 0 0.020
muscular disease DOID:0080000 0 0.020
myopathy DOID:423 0 0.020
musculoskeletal system disease DOID:17 0 0.020
neuropathy DOID:870 0 0.016
neuromuscular disease DOID:440 0 0.013
hematopoietic system disease DOID:74 0 0.013
immune system disease DOID:2914 0 0.013
eye and adnexa disease DOID:1492 0 0.012
sensory system disease DOID:0050155 0 0.012