Mus musculus

0 known processes

Timd4

T-cell immunoglobulin and mucin domain containing 4

(Aliases: TIM-4,Tim4,B430010N18Rik)

Timd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
activation of immune response GO:0002253 138 0.126
cytokine production GO:0001816 319 0.104
innate immune response GO:0045087 157 0.081
inflammatory response GO:0006954 244 0.074
t cell activation GO:0042110 289 0.070
defense response to other organism GO:0098542 197 0.069
regulation of defense response GO:0031347 233 0.066
immune effector process GO:0002252 321 0.065
cellular amino acid metabolic process GO:0006520 103 0.065
cellular nitrogen compound catabolic process GO:0044270 280 0.063
regulation of lymphocyte activation GO:0051249 240 0.061
regulation of inflammatory response GO:0050727 147 0.061
organic cyclic compound catabolic process GO:1901361 295 0.059
cellular chemical homeostasis GO:0055082 215 0.058
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.056
negative regulation of immune system process GO:0002683 209 0.056
cellular amine metabolic process GO:0044106 44 0.055
cell adhesion GO:0007155 329 0.054
regulation of cell activation GO:0050865 289 0.054
Mouse
cellular homeostasis GO:0019725 240 0.053
cellular ketone metabolic process GO:0042180 84 0.053
immune response regulating signaling pathway GO:0002764 125 0.053
metal ion homeostasis GO:0055065 189 0.052
regulation of cellular ketone metabolic process GO:0010565 66 0.050
regulation of secretion by cell GO:1903530 249 0.050
cation transport GO:0006812 399 0.049
regulation of cytokine production GO:0001817 266 0.049
sequestering of calcium ion GO:0051208 18 0.048
immune response activating signal transduction GO:0002757 116 0.047
cellular metal ion homeostasis GO:0006875 151 0.045
negative regulation of protein metabolic process GO:0051248 282 0.044
regulation of t cell activation GO:0050863 170 0.042
sequestering of metal ion GO:0051238 19 0.042
nucleoside phosphate metabolic process GO:0006753 338 0.042
regulation of secretion GO:0051046 274 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.041
cation homeostasis GO:0055080 212 0.041
ras protein signal transduction GO:0007265 77 0.041
divalent inorganic cation transport GO:0072511 178 0.041
aromatic compound catabolic process GO:0019439 286 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
nucleotide metabolic process GO:0009117 332 0.040
negative regulation of cell activation GO:0050866 111 0.039
regulation of vesicle mediated transport GO:0060627 139 0.039
calcium ion homeostasis GO:0055074 127 0.038
regulation of ion transport GO:0043269 215 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.037
cellular ion homeostasis GO:0006873 165 0.037
purine ribonucleoside catabolic process GO:0046130 205 0.036
nucleotide catabolic process GO:0009166 217 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
amine metabolic process GO:0009308 45 0.034
response to molecule of bacterial origin GO:0002237 143 0.034
positive regulation of cytokine production GO:0001819 174 0.034
regulation of cellular catabolic process GO:0031329 242 0.033
purine containing compound metabolic process GO:0072521 311 0.033
heterocycle catabolic process GO:0046700 280 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
mature dendritic cell differentiation GO:0097029 3 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
oxidation reduction process GO:0055114 342 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.030
regulation of protein localization GO:0032880 231 0.029
regulation of ion homeostasis GO:2000021 64 0.029
transmembrane transport GO:0055085 412 0.029
organonitrogen compound catabolic process GO:1901565 264 0.028
regulation of response to wounding GO:1903034 189 0.028
maintenance of location GO:0051235 89 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of establishment of protein localization GO:0070201 181 0.028
lymphocyte differentiation GO:0030098 242 0.028
cation transmembrane transport GO:0098655 266 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
divalent metal ion transport GO:0070838 172 0.027
leukocyte mediated immunity GO:0002443 174 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
regulation of protein transport GO:0051223 163 0.027
nitrogen compound transport GO:0071705 271 0.027
organophosphate catabolic process GO:0046434 232 0.027
divalent inorganic cation homeostasis GO:0072507 138 0.026
homeostasis of number of cells GO:0048872 210 0.026
protein maturation GO:0051604 176 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
regulation of leukocyte proliferation GO:0070663 121 0.026
macromolecule catabolic process GO:0009057 281 0.026
regulation of innate immune response GO:0045088 91 0.026
cell type specific apoptotic process GO:0097285 268 0.026
cellular calcium ion homeostasis GO:0006874 119 0.025
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.025
regulation of monocyte chemotaxis GO:0090025 3 0.025
antigen processing and presentation GO:0019882 47 0.025
regulation of leukocyte mediated immunity GO:0002703 104 0.025
positive regulation of defense response GO:0031349 124 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
endocytosis GO:0006897 168 0.024
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
positive regulation of adaptive immune response GO:0002821 61 0.024
cellular divalent inorganic cation homeostasis GO:0072503 127 0.024
positive regulation of monocyte chemotaxis GO:0090026 2 0.024
cytoplasmic transport GO:0016482 234 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
positive regulation of secretion GO:0051047 130 0.023
peptidyl amino acid modification GO:0018193 336 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
regulation of hydrolase activity GO:0051336 246 0.023
negative regulation of molecular function GO:0044092 258 0.023
sensory perception GO:0007600 245 0.023
exocytosis GO:0006887 121 0.023
nucleoside metabolic process GO:0009116 246 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
purine nucleotide catabolic process GO:0006195 211 0.023
ribonucleoside metabolic process GO:0009119 245 0.022
regulation of cell migration GO:0030334 219 0.022
leukocyte proliferation GO:0070661 172 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
nucleoside catabolic process GO:0009164 206 0.022
response to lipopolysaccharide GO:0032496 128 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
angiogenesis GO:0001525 201 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
negative regulation of lymphocyte activation GO:0051250 91 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
positive regulation of immune effector process GO:0002699 107 0.021
regulation of intracellular transport GO:0032386 159 0.021
mapk cascade GO:0000165 281 0.021
muscle tissue development GO:0060537 308 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
single organism cell adhesion GO:0098602 156 0.021
regulation of homeostatic process GO:0032844 182 0.021
membrane organization GO:0061024 245 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
calcium ion transport GO:0006816 159 0.020
regulation of t cell proliferation GO:0042129 92 0.020
protein processing GO:0016485 163 0.020
toll like receptor signaling pathway GO:0002224 38 0.020
positive regulation of cell death GO:0010942 224 0.020
lymphocyte proliferation GO:0046651 164 0.020
rho protein signal transduction GO:0007266 32 0.020
detection of fungus GO:0016046 2 0.019
positive regulation of t cell activation GO:0050870 101 0.019
detection of yeast GO:0001879 2 0.019
ion transmembrane transport GO:0034220 361 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
regulation of cell adhesion GO:0030155 154 0.019
apoptotic signaling pathway GO:0097190 306 0.019
regulation of hormone levels GO:0010817 211 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
regulation of mapk cascade GO:0043408 248 0.019
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.019
cellular lipid metabolic process GO:0044255 323 0.019
cytokine secretion GO:0050663 72 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
protein secretion GO:0009306 111 0.019
purine containing compound catabolic process GO:0072523 213 0.019
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.019
positive regulation of innate immune response GO:0045089 80 0.018
striated muscle tissue development GO:0014706 293 0.018
protein catabolic process GO:0030163 221 0.018
leukocyte migration GO:0050900 124 0.018
negative regulation of homeostatic process GO:0032845 71 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
alpha beta t cell activation GO:0046631 91 0.018
leukocyte differentiation GO:0002521 342 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
regulation of membrane potential GO:0042391 192 0.018
regulation of organelle organization GO:0033043 289 0.017
cell recognition GO:0008037 83 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
chemotaxis GO:0006935 247 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
cytosolic calcium ion homeostasis GO:0051480 70 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
wound healing GO:0042060 157 0.016
positive regulation of protein transport GO:0051222 93 0.016
negative regulation of secretion by cell GO:1903531 54 0.016
myeloid cell differentiation GO:0030099 233 0.016
regulation of cell motility GO:2000145 236 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
negative regulation of phospholipase activity GO:0010519 4 0.016
anion transport GO:0006820 177 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
negative regulation of macrophage apoptotic process GO:2000110 3 0.016
cytosolic calcium ion transport GO:0060401 48 0.016
organelle localization GO:0051640 179 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
regulation of body fluid levels GO:0050878 162 0.015
blood vessel morphogenesis GO:0048514 285 0.015
positive regulation of cell activation GO:0050867 158 0.015
Mouse
regulation of protein maturation GO:1903317 96 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
b cell activation GO:0042113 161 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
negative regulation of hydrolase activity GO:0051346 71 0.015
carbohydrate homeostasis GO:0033500 128 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.015
dna metabolic process GO:0006259 303 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
blood circulation GO:0008015 195 0.015
response to organonitrogen compound GO:0010243 246 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
regulation of blood pressure GO:0008217 93 0.014
cofactor metabolic process GO:0051186 80 0.014
cellular response to lipid GO:0071396 145 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
positive regulation of leukocyte mediated immunity GO:0002705 70 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of renin secretion into blood stream GO:1900133 4 0.014
interferon gamma production GO:0032609 67 0.014
regulation of cell projection organization GO:0031344 206 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
cellular protein complex assembly GO:0043623 116 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
regulation of leukocyte apoptotic process GO:2000106 56 0.014
regulation of protein secretion GO:0050708 82 0.014
leukocyte apoptotic process GO:0071887 71 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
negative regulation of protein modification process GO:0031400 163 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
ossification GO:0001503 216 0.014
protein kinase b signaling GO:0043491 74 0.014
interleukin 12 secretion GO:0072610 3 0.014
response to acid chemical GO:0001101 111 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
multicellular organismal signaling GO:0035637 91 0.014
adaptive immune response GO:0002250 155 0.014
positive regulation of cell development GO:0010720 237 0.014
forebrain development GO:0030900 302 0.014
t cell receptor signaling pathway GO:0050852 46 0.014
response to growth factor GO:0070848 198 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
action potential GO:0001508 78 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
protein ubiquitination GO:0016567 171 0.013
cell activation involved in immune response GO:0002263 126 0.013
organic hydroxy compound transport GO:0015850 93 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
positive regulation of response to wounding GO:1903036 66 0.013
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
calcium ion transport into cytosol GO:0060402 48 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
humoral immune response GO:0006959 57 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
hemostasis GO:0007599 78 0.013
regulation of anatomical structure size GO:0090066 178 0.013
positive regulation of cell motility GO:2000147 116 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
regulation of calcium ion transport into cytosol GO:0010522 31 0.013
steroid metabolic process GO:0008202 119 0.013
organelle fission GO:0048285 170 0.013
organic anion transport GO:0015711 137 0.013
regulation of endocytosis GO:0030100 69 0.013
striated muscle cell development GO:0055002 125 0.013
regulation of metal ion transport GO:0010959 106 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
glucose homeostasis GO:0042593 128 0.012
organic acid transport GO:0015849 101 0.012
t cell differentiation GO:0030217 174 0.012
cytokine biosynthetic process GO:0042089 68 0.012
anatomical structure homeostasis GO:0060249 145 0.012
peptide transport GO:0015833 133 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
regulation of kinase activity GO:0043549 249 0.012
gland development GO:0048732 330 0.012
mitotic cell cycle GO:0000278 195 0.012
regulation of system process GO:0044057 200 0.012
protein localization to nucleus GO:0034504 121 0.012
positive regulation of leukocyte proliferation GO:0070665 73 0.012
negative regulation of defense response GO:0031348 77 0.012
antigen receptor mediated signaling pathway GO:0050851 64 0.012
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.012
camera type eye development GO:0043010 266 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
negative regulation of lymphocyte proliferation GO:0050672 45 0.012
protein polymerization GO:0051258 57 0.012
alcohol metabolic process GO:0006066 116 0.012
skeletal system development GO:0001501 356 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
negative regulation of t cell activation GO:0050868 65 0.012
circulatory system process GO:0003013 197 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
negative regulation of phagocytosis GO:0050765 4 0.012
negative regulation of t cell proliferation GO:0042130 38 0.012
regulation of cell cycle GO:0051726 281 0.012
microglial cell activation GO:0001774 3 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
release of sequestered calcium ion into cytosol GO:0051209 42 0.011
neuronal action potential GO:0019228 54 0.011
small molecule biosynthetic process GO:0044283 132 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of adaptive immune response GO:0002819 90 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
fatty acid metabolic process GO:0006631 121 0.011
synaptic transmission GO:0007268 329 0.011
regulation of protein kinase b signaling GO:0051896 56 0.011
protein localization to organelle GO:0033365 185 0.011
gtp metabolic process GO:0046039 144 0.011
positive regulation of protein modification process GO:0031401 299 0.011
peptide secretion GO:0002790 114 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
norepinephrine secretion GO:0048243 2 0.011
thrombin receptor signaling pathway GO:0070493 2 0.011
negative regulation of proteolysis GO:0045861 74 0.011
amide transport GO:0042886 138 0.011
regulation of interleukin 2 production GO:0032663 28 0.011
regulation of alpha beta t cell activation GO:0046634 53 0.011
t cell mediated immunity GO:0002456 50 0.011
regulation of protein processing GO:0070613 96 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
t cell proliferation GO:0042098 120 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
fat cell differentiation GO:0045444 160 0.011
leukocyte chemotaxis GO:0030595 69 0.011
microtubule based process GO:0007017 236 0.011
response to extracellular stimulus GO:0009991 127 0.011
cellular response to acid chemical GO:0071229 68 0.010
regulation of proteolysis GO:0030162 164 0.010
response to nutrient levels GO:0031667 109 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
intracellular protein transport GO:0006886 204 0.010
positive regulation of alpha beta t cell activation GO:0046635 39 0.010
transepithelial chloride transport GO:0030321 4 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
muscle cell differentiation GO:0042692 261 0.010
positive regulation of nervous system development GO:0051962 221 0.010
defense response to bacterium GO:0042742 119 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010
cellular protein catabolic process GO:0044257 155 0.010
transmission of nerve impulse GO:0019226 76 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
fertilization GO:0009566 127 0.010
regulation of cellular response to stress GO:0080135 159 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010

Timd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.028
disease of anatomical entity DOID:7 0 0.028
hematopoietic system disease DOID:74 0 0.028
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.014
connective tissue disease DOID:65 0 0.013
sensory system disease DOID:0050155 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011