Mus musculus

123 known processes

S1pr1

sphingosine-1-phosphate receptor 1

(Aliases: Lpb1,AI849002,S1p1,S1p,Edg1)

S1pr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.824
small gtpase mediated signal transduction GO:0007264 97 0.804
Mouse
ras protein signal transduction GO:0007265 77 0.741
Mouse
cellular amine metabolic process GO:0044106 44 0.657
regulation of cellular amine metabolic process GO:0033238 20 0.615
mapk cascade GO:0000165 281 0.568
Mouse
cellular ketone metabolic process GO:0042180 84 0.539
rho protein signal transduction GO:0007266 32 0.516
Mouse
cellular amino acid metabolic process GO:0006520 103 0.484
purine nucleotide metabolic process GO:0006163 302 0.463
Rat
regulation of cellular amino acid metabolic process GO:0006521 5 0.441
cell adhesion GO:0007155 329 0.430
inflammatory response GO:0006954 244 0.411
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.384
nucleotide metabolic process GO:0009117 332 0.370
Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.349
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.330
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.308
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.304
nucleoside phosphate metabolic process GO:0006753 338 0.299
Rat
cytokine production GO:0001816 319 0.270
Mouse
regulation of cytokine production GO:0001817 266 0.262
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.257
peptidyl tyrosine phosphorylation GO:0018108 143 0.254
fat cell differentiation GO:0045444 160 0.241
regulation of transferase activity GO:0051338 263 0.228
Mouse
single organismal cell cell adhesion GO:0016337 131 0.221
regulation of kinase activity GO:0043549 249 0.215
Mouse
regulation of defense response GO:0031347 233 0.206
negative regulation of molecular function GO:0044092 258 0.200
g protein coupled receptor signaling pathway GO:0007186 243 0.194
nucleoside catabolic process GO:0009164 206 0.185
Rat
ribonucleotide metabolic process GO:0009259 291 0.184
Rat
positive regulation of growth GO:0045927 104 0.180
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.176
Rat
forebrain development GO:0030900 302 0.170
cellular response to cytokine stimulus GO:0071345 189 0.167
peptidyl amino acid modification GO:0018193 336 0.166
regulation of nucleotide metabolic process GO:0006140 169 0.161
Rat
negative regulation of cellular protein metabolic process GO:0032269 247 0.160
carbohydrate derivative biosynthetic process GO:1901137 183 0.159
ribose phosphate metabolic process GO:0019693 291 0.157
Rat
ribonucleoside catabolic process GO:0042454 206 0.154
Rat
regulation of response to wounding GO:1903034 189 0.154
nucleobase containing small molecule metabolic process GO:0055086 352 0.153
Rat
positive regulation of protein modification process GO:0031401 299 0.152
Mouse
digestive tract development GO:0048565 190 0.151
nucleotide catabolic process GO:0009166 217 0.150
Rat
blood circulation GO:0008015 195 0.146
negative regulation of immune system process GO:0002683 209 0.146
carbohydrate metabolic process GO:0005975 230 0.146
striated muscle tissue development GO:0014706 293 0.142
regulation of inflammatory response GO:0050727 147 0.142
regulation of purine nucleotide metabolic process GO:1900542 169 0.142
Rat
multicellular organism growth GO:0035264 161 0.140
protein localization to organelle GO:0033365 185 0.137
negative regulation of phosphorus metabolic process GO:0010563 184 0.135
organic cyclic compound catabolic process GO:1901361 295 0.135
Rat
response to organonitrogen compound GO:0010243 246 0.134
glycosyl compound catabolic process GO:1901658 206 0.131
Rat
nitrogen compound transport GO:0071705 271 0.131
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.130
positive regulation of mapk cascade GO:0043410 170 0.127
Mouse
muscle cell differentiation GO:0042692 261 0.126
stem cell development GO:0048864 219 0.126
nucleoside metabolic process GO:0009116 246 0.125
Rat
tissue migration GO:0090130 68 0.125
negative regulation of cell proliferation GO:0008285 296 0.124
peptidyl tyrosine modification GO:0018212 145 0.122
purine ribonucleotide metabolic process GO:0009150 290 0.121
Rat
regulation of membrane potential GO:0042391 192 0.119
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.118
Rat
regulation of rho protein signal transduction GO:0035023 71 0.115
Mouse
purine containing compound metabolic process GO:0072521 311 0.114
Rat
aromatic compound catabolic process GO:0019439 286 0.113
Rat
purine ribonucleoside metabolic process GO:0046128 241 0.111
Rat
heart contraction GO:0060047 93 0.110
positive regulation of neuron differentiation GO:0045666 141 0.110
Mouse
axonogenesis GO:0007409 274 0.109
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.109
Mouse
tyrosine phosphorylation of stat protein GO:0007260 23 0.108
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.105
nucleotide biosynthetic process GO:0009165 78 0.103
nucleoside triphosphate metabolic process GO:0009141 230 0.101
Rat
muscle adaptation GO:0043500 39 0.101
response to organic cyclic compound GO:0014070 198 0.100
regulation of ras protein signal transduction GO:0046578 114 0.100
Mouse Rat
wound healing GO:0042060 157 0.095
divalent inorganic cation homeostasis GO:0072507 138 0.095
Mouse Rat
organophosphate catabolic process GO:0046434 232 0.095
Rat
telencephalon development GO:0021537 186 0.095
cytokine mediated signaling pathway GO:0019221 115 0.095
ribonucleotide catabolic process GO:0009261 208 0.094
Rat
negative regulation of cellular amine metabolic process GO:0033239 1 0.093
homeostasis of number of cells GO:0048872 210 0.093
cellular response to peptide GO:1901653 92 0.091
cyclic nucleotide metabolic process GO:0009187 59 0.091
organonitrogen compound biosynthetic process GO:1901566 192 0.090
circulatory system process GO:0003013 197 0.090
cellular response to organonitrogen compound GO:0071417 145 0.090
regulation of voltage gated calcium channel activity GO:1901385 4 0.089
gtp metabolic process GO:0046039 144 0.084
Rat
regulation of cell motility GO:2000145 236 0.084
Rat
purine nucleoside triphosphate catabolic process GO:0009146 203 0.084
Rat
digestive system development GO:0055123 200 0.083
ribonucleoside triphosphate metabolic process GO:0009199 220 0.083
Rat
regulation of neuron projection development GO:0010975 169 0.083
Mouse
regulation of anatomical structure size GO:0090066 178 0.082
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.082
Rat
regulation of mapk cascade GO:0043408 248 0.082
Mouse
regulation of system process GO:0044057 200 0.082
positive regulation of cell activation GO:0050867 158 0.081
organophosphate biosynthetic process GO:0090407 122 0.081
regulation of insulin receptor signaling pathway GO:0046626 21 0.081
small molecule biosynthetic process GO:0044283 132 0.080
regulation of cellular response to stress GO:0080135 159 0.078
negative regulation of cellular component organization GO:0051129 194 0.078
Rat
metal ion homeostasis GO:0055065 189 0.077
Mouse Rat
regulation of leukocyte differentiation GO:1902105 159 0.077
cellular nitrogen compound catabolic process GO:0044270 280 0.076
Rat
organonitrogen compound catabolic process GO:1901565 264 0.076
Rat
carboxylic acid biosynthetic process GO:0046394 86 0.076
positive regulation of neuron projection development GO:0010976 79 0.075
Mouse
cardiac muscle tissue development GO:0048738 130 0.075
neuronal action potential GO:0019228 54 0.075
negative regulation of protein phosphorylation GO:0001933 126 0.075
anion transport GO:0006820 177 0.075
purine containing compound catabolic process GO:0072523 213 0.074
Rat
chemotaxis GO:0006935 247 0.074
response to lipopolysaccharide GO:0032496 128 0.074
multicellular organismal signaling GO:0035637 91 0.072
Rat
ribonucleoside triphosphate catabolic process GO:0009203 199 0.072
Rat
leukocyte differentiation GO:0002521 342 0.072
jak stat cascade GO:0007259 42 0.071
camera type eye development GO:0043010 266 0.070
positive regulation of cell death GO:0010942 224 0.070
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.069
cognition GO:0050890 149 0.069
regulation of cellular component biogenesis GO:0044087 181 0.068
Rat
blood coagulation GO:0007596 76 0.068
purine nucleotide catabolic process GO:0006195 211 0.067
Rat
adaptive immune response GO:0002250 155 0.067
extrinsic apoptotic signaling pathway GO:0097191 126 0.067
positive regulation of cell development GO:0010720 237 0.067
Mouse
skeletal muscle organ development GO:0060538 163 0.066
regulation of cell projection organization GO:0031344 206 0.066
Mouse
regulation of hormone levels GO:0010817 211 0.066
cellular homeostasis GO:0019725 240 0.066
Mouse Rat
organophosphate ester transport GO:0015748 28 0.066
negative regulation of endothelial cell migration GO:0010596 4 0.066
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.065
lymphocyte differentiation GO:0030098 242 0.065
regulation of cell migration GO:0030334 219 0.064
Rat
blood vessel morphogenesis GO:0048514 285 0.064
regulation of rho gtpase activity GO:0032319 58 0.064
positive regulation of nucleotide metabolic process GO:0045981 114 0.064
Rat
ribonucleoside metabolic process GO:0009119 245 0.063
Rat
ribonucleotide biosynthetic process GO:0009260 59 0.063
amide transport GO:0042886 138 0.062
glycosyl compound metabolic process GO:1901657 246 0.062
Rat
muscle system process GO:0003012 141 0.061
cell growth GO:0016049 130 0.061
Mouse
macromolecule catabolic process GO:0009057 281 0.061
regulation of lymphocyte activation GO:0051249 240 0.060
nucleoside phosphate catabolic process GO:1901292 222 0.060
Rat
guanosine containing compound catabolic process GO:1901069 144 0.060
Rat
purine nucleotide biosynthetic process GO:0006164 65 0.060
stem cell maintenance GO:0019827 130 0.059
extracellular matrix organization GO:0030198 147 0.059
calcium ion homeostasis GO:0055074 127 0.058
Mouse Rat
cellular response to molecule of bacterial origin GO:0071219 83 0.058
transmembrane transport GO:0055085 412 0.058
peptide secretion GO:0002790 114 0.058
heart morphogenesis GO:0003007 178 0.058
angiogenesis GO:0001525 201 0.057
leukocyte chemotaxis GO:0030595 69 0.057
digestive tract morphogenesis GO:0048546 147 0.056
gtp catabolic process GO:0006184 143 0.056
Rat
single organism cell adhesion GO:0098602 156 0.056
nucleoside triphosphate catabolic process GO:0009143 205 0.056
Rat
axon guidance GO:0007411 141 0.056
gland development GO:0048732 330 0.055
immune response regulating signaling pathway GO:0002764 125 0.055
oxidation reduction process GO:0055114 342 0.055
regulation of apoptotic signaling pathway GO:2001233 197 0.054
regulation of gtp catabolic process GO:0033124 113 0.053
Rat
cellular response to organic cyclic compound GO:0071407 87 0.053
regulation of neuron differentiation GO:0045664 281 0.053
Mouse
negative regulation of cell development GO:0010721 169 0.053
maintenance of location GO:0051235 89 0.053
cyclic nucleotide biosynthetic process GO:0009190 44 0.051
compound eye development GO:0048749 1 0.051
regulation of secretion by cell GO:1903530 249 0.051
purine nucleoside catabolic process GO:0006152 205 0.051
Rat
carbohydrate transport GO:0008643 62 0.050
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.050
Rat
purine containing compound biosynthetic process GO:0072522 70 0.050
ribose phosphate biosynthetic process GO:0046390 59 0.050
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.050
regulation of nucleotide biosynthetic process GO:0030808 34 0.050
regulation of secretion GO:0051046 274 0.050
regulation of heart contraction GO:0008016 77 0.049
leukocyte migration GO:0050900 124 0.049
memory GO:0007613 58 0.049
organic anion transport GO:0015711 137 0.049
protein localization to nucleus GO:0034504 121 0.049
cellular response to lipopolysaccharide GO:0071222 77 0.049
positive regulation of lymphocyte activation GO:0051251 140 0.049
response to retinoic acid GO:0032526 56 0.048
glial cell differentiation GO:0010001 131 0.048
stem cell differentiation GO:0048863 268 0.048
nucleoside phosphate biosynthetic process GO:1901293 79 0.048
glycoprotein biosynthetic process GO:0009101 89 0.048
camp metabolic process GO:0046058 40 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.047
Rat
cell activation involved in immune response GO:0002263 126 0.047
t cell activation GO:0042110 289 0.047
cellular response to hormone stimulus GO:0032870 150 0.047
regulation of body fluid levels GO:0050878 162 0.046
t cell differentiation GO:0030217 174 0.046
regulation of anion transport GO:0044070 27 0.046
cellular lipid metabolic process GO:0044255 323 0.046
regulation of homeostatic process GO:0032844 182 0.046
negative regulation of transferase activity GO:0051348 85 0.046
myeloid cell homeostasis GO:0002262 114 0.046
regulation of muscle system process GO:0090257 80 0.046
positive regulation of programmed cell death GO:0043068 218 0.045
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.045
negative regulation of protein modification process GO:0031400 163 0.045
activation of janus kinase activity GO:0042976 2 0.045
positive regulation of nervous system development GO:0051962 221 0.045
Mouse
negative regulation of cell activation GO:0050866 111 0.045
t cell activation involved in immune response GO:0002286 43 0.044
negative regulation of phosphorylation GO:0042326 166 0.044
engulfment of apoptotic cell GO:0043652 3 0.044
heterocycle catabolic process GO:0046700 280 0.044
Rat
regulation of blood circulation GO:1903522 93 0.044
positive regulation of leukocyte differentiation GO:1902107 86 0.044
anatomical structure homeostasis GO:0060249 145 0.044
peptide transport GO:0015833 133 0.044
glucose transport GO:0015758 56 0.044
erythrocyte differentiation GO:0030218 88 0.043
heart process GO:0003015 94 0.043
regulation of muscle tissue development GO:1901861 97 0.043
immune response activating signal transduction GO:0002757 116 0.043
regulation of protein kinase activity GO:0045859 232 0.043
Mouse
antigen receptor mediated signaling pathway GO:0050851 64 0.043
negative regulation of phospholipase activity GO:0010519 4 0.042
cellular carbohydrate metabolic process GO:0044262 119 0.042
myeloid cell differentiation GO:0030099 233 0.042
cation transport GO:0006812 399 0.042
i kappab kinase nf kappab signaling GO:0007249 85 0.042
wnt signaling pathway GO:0016055 188 0.042
developmental growth involved in morphogenesis GO:0060560 138 0.042
male gamete generation GO:0048232 285 0.041
sensory organ morphogenesis GO:0090596 242 0.041
formation of primary germ layer GO:0001704 77 0.041
purine ribonucleotide biosynthetic process GO:0009152 59 0.041
negative regulation of leukocyte differentiation GO:1902106 51 0.041
endocytosis GO:0006897 168 0.041
activation of immune response GO:0002253 138 0.041
cellular component assembly involved in morphogenesis GO:0010927 139 0.041
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.040
placenta development GO:0001890 140 0.040
ameboidal type cell migration GO:0001667 128 0.040
regulation of binding GO:0051098 111 0.040
cell maturation GO:0048469 127 0.040
leukocyte activation involved in immune response GO:0002366 126 0.040
positive regulation of cytokine production GO:0001819 174 0.040
epidermis development GO:0008544 187 0.039
positive regulation of cell migration GO:0030335 109 0.039
Rat
glycoprotein metabolic process GO:0009100 116 0.039
regulation of protein localization GO:0032880 231 0.039
neuron migration GO:0001764 122 0.039
insulin secretion GO:0030073 89 0.039
granulocyte chemotaxis GO:0071621 39 0.039
immune effector process GO:0002252 321 0.039
developmental maturation GO:0021700 193 0.038
regulation of camp metabolic process GO:0030814 30 0.038
protein localization to membrane GO:0072657 108 0.038
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.038
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.038
skeletal muscle cell differentiation GO:0035914 66 0.038
regulation of t cell activation GO:0050863 170 0.038
alcohol metabolic process GO:0006066 116 0.037
positive regulation of apoptotic process GO:0043065 217 0.037
cellular response to lipid GO:0071396 145 0.037
lung epithelial cell differentiation GO:0060487 29 0.037
regulation of cell adhesion GO:0030155 154 0.037
cellular response to biotic stimulus GO:0071216 92 0.037
regulation of nucleotide catabolic process GO:0030811 122 0.037
Rat
nuclear transport GO:0051169 139 0.037
response to oxidative stress GO:0006979 123 0.036
myelination GO:0042552 74 0.036
apoptotic signaling pathway GO:0097190 306 0.036
organic acid biosynthetic process GO:0016053 86 0.036
cell type specific apoptotic process GO:0097285 268 0.036
cation homeostasis GO:0055080 212 0.036
Mouse Rat
learning or memory GO:0007611 148 0.035
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.035
chromatin modification GO:0016568 187 0.035
monosaccharide metabolic process GO:0005996 106 0.035
regulation of cell substrate adhesion GO:0010810 73 0.034
positive regulation of gtp catabolic process GO:0033126 85 0.034
Rat
alpha beta t cell activation GO:0046631 91 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.034
Rat
action potential GO:0001508 78 0.034
regulation of cell cycle process GO:0010564 160 0.034
Mouse
positive regulation of gtpase activity GO:0043547 85 0.034
Rat
regulation of type 2 immune response GO:0002828 18 0.033
insulin receptor signaling pathway GO:0008286 49 0.033
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.033
glycosylation GO:0070085 62 0.033
regulation of alpha beta t cell activation GO:0046634 53 0.033
cytoplasmic transport GO:0016482 234 0.033
brown fat cell differentiation GO:0050873 36 0.033
regulation of nucleoside metabolic process GO:0009118 130 0.033
Rat
rhodopsin mediated signaling pathway GO:0016056 4 0.032
kidney development GO:0001822 213 0.032
muscle tissue development GO:0060537 308 0.032
response to peptide hormone GO:0043434 127 0.032
negative regulation of intracellular signal transduction GO:1902532 167 0.032
carbohydrate biosynthetic process GO:0016051 74 0.032
regulation of jak stat cascade GO:0046425 34 0.032
endothelial cell migration GO:0043542 44 0.032
b cell activation GO:0042113 161 0.032
negative regulation of apoptotic signaling pathway GO:2001234 104 0.032
cellular response to peptide hormone stimulus GO:0071375 92 0.032
cyclic purine nucleotide metabolic process GO:0052652 43 0.032
positive regulation of cell projection organization GO:0031346 95 0.032
Mouse
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
Rat
regulation of ion transport GO:0043269 215 0.031
ion transmembrane transport GO:0034220 361 0.031
regulation of protein serine threonine kinase activity GO:0071900 157 0.031
Mouse
neuron projection guidance GO:0097485 141 0.031
cytosolic calcium ion homeostasis GO:0051480 70 0.031
Rat
transmission of nerve impulse GO:0019226 76 0.031
Rat
regulation of cell activation GO:0050865 289 0.031
regulation of ras gtpase activity GO:0032318 88 0.031
Rat
cellular response to growth factor stimulus GO:0071363 197 0.031
actin cytoskeleton organization GO:0030036 220 0.031
regulation of production of molecular mediator of immune response GO:0002700 65 0.031
vascular process in circulatory system GO:0003018 62 0.030
cellular calcium ion homeostasis GO:0006874 119 0.030
Mouse Rat
peptide hormone secretion GO:0030072 109 0.030
lipid biosynthetic process GO:0008610 179 0.030
epithelial cell development GO:0002064 159 0.030
response to light stimulus GO:0009416 135 0.030
response to acid chemical GO:0001101 111 0.030
positive regulation of cellular catabolic process GO:0031331 148 0.030
Rat
negative regulation of kinase activity GO:0033673 81 0.030
negative regulation of cell migration GO:0030336 59 0.030
positive regulation of jak stat cascade GO:0046427 22 0.030
muscle contraction GO:0006936 101 0.030
regulation of lymphocyte differentiation GO:0045619 107 0.030
regulation of vasculature development GO:1901342 88 0.030
negative regulation of neuron death GO:1901215 98 0.030
regulation of cell cycle GO:0051726 281 0.030
Mouse
glucose homeostasis GO:0042593 128 0.030
Mouse
positive regulation of cell substrate adhesion GO:0010811 47 0.029
membrane organization GO:0061024 245 0.029
second messenger mediated signaling GO:0019932 73 0.029
gastrulation GO:0007369 116 0.029
reactive oxygen species biosynthetic process GO:1903409 8 0.029
regulation of adaptive immune response GO:0002819 90 0.029
camp biosynthetic process GO:0006171 31 0.029
negative regulation of cell fate specification GO:0009996 4 0.029
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.029
hexose transport GO:0008645 56 0.029
heart growth GO:0060419 45 0.029
cardiac muscle hypertrophy GO:0003300 23 0.029
ensheathment of neurons GO:0007272 76 0.029
positive regulation of ras gtpase activity GO:0032320 65 0.029
Rat
regulation of leukocyte mediated immunity GO:0002703 104 0.029
response to molecule of bacterial origin GO:0002237 143 0.029
defense response to other organism GO:0098542 197 0.029
protein maturation GO:0051604 176 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
blastocyst development GO:0001824 80 0.028
response to radiation GO:0009314 165 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
axon ensheathment GO:0008366 76 0.028
regulation of fat cell differentiation GO:0045598 81 0.028
liver development GO:0001889 66 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
positive regulation of inflammatory response GO:0050729 47 0.028
learning GO:0007612 98 0.028
trabecula morphogenesis GO:0061383 40 0.028
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 8 0.028
regulation of hydrolase activity GO:0051336 246 0.028
Rat
intrinsic apoptotic signaling pathway GO:0097193 132 0.028
rhythmic process GO:0048511 174 0.028
myotube differentiation GO:0014902 105 0.028
response to insulin GO:0032868 100 0.028
telencephalon cell migration GO:0022029 55 0.027
monosaccharide transport GO:0015749 58 0.027
cardiac chamber development GO:0003205 108 0.027
positive regulation of secretion by cell GO:1903532 114 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
guanosine containing compound metabolic process GO:1901068 144 0.027
Rat
regulation of cellular catabolic process GO:0031329 242 0.027
Rat
sterol homeostasis GO:0055092 45 0.027
phospholipid transfer to membrane GO:0006649 2 0.027
granulocyte migration GO:0097530 43 0.026
embryonic epithelial tube formation GO:0001838 130 0.026
lymphocyte homeostasis GO:0002260 64 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.026
chromatin organization GO:0006325 206 0.026
regulation of cell size GO:0008361 72 0.026
Mouse
platelet activation GO:0030168 40 0.026
positive regulation of camp metabolic process GO:0030816 19 0.026
regulation of organelle organization GO:0033043 289 0.026
Mouse Rat
immunoglobulin mediated immune response GO:0016064 69 0.026
lipid homeostasis GO:0055088 63 0.026
positive regulation of intracellular transport GO:0032388 70 0.026
regulation of muscle contraction GO:0006937 49 0.026
mesenchymal cell differentiation GO:0048762 107 0.026
protein ubiquitination GO:0016567 171 0.026
activation of mapk activity GO:0000187 59 0.026
Mouse
positive regulation of defense response GO:0031349 124 0.025
generation of precursor metabolites and energy GO:0006091 103 0.025
skin development GO:0043588 220 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.025
negative regulation of neuron apoptotic process GO:0043524 92 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
lipid localization GO:0010876 126 0.025
response to oxygen levels GO:0070482 62 0.025
regulation of leukocyte apoptotic process GO:2000106 56 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
Mouse
protein processing GO:0016485 163 0.024
negative regulation of neuron differentiation GO:0045665 101 0.024
tissue remodeling GO:0048771 102 0.024
regulation of phospholipid transport GO:2001138 4 0.024
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
cytokine production involved in immune response GO:0002367 34 0.024
organ growth GO:0035265 117 0.024
regulation of t cell differentiation GO:0045580 83 0.024
regulation of blood vessel size GO:0050880 56 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
steroid metabolic process GO:0008202 119 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
Rat
sequestering of calcium ion GO:0051208 18 0.023
sequestering of metal ion GO:0051238 19 0.023
phosphatidylinositol mediated signaling GO:0048015 41 0.023
regulation of purine nucleotide catabolic process GO:0033121 122 0.023
Rat
protein modification by small protein conjugation GO:0032446 187 0.023
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.023
regulation of myeloid cell differentiation GO:0045637 96 0.023
neuron apoptotic process GO:0051402 142 0.023
regulation of extent of cell growth GO:0061387 52 0.023
Mouse
immunoglobulin production GO:0002377 73 0.023
respiratory tube development GO:0030323 167 0.023
regulation of camp biosynthetic process GO:0030817 25 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
gliogenesis GO:0042063 141 0.023
cd4 positive alpha beta t cell activation GO:0035710 45 0.023
regulation of engulfment of apoptotic cell GO:1901074 2 0.023
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.022
Mouse
negative regulation of inflammatory response GO:0050728 61 0.022
cardiac chamber morphogenesis GO:0003206 93 0.022
sialylation GO:0097503 14 0.022
endomembrane system organization GO:0010256 147 0.022
anatomical structure maturation GO:0071695 49 0.022
muscle hypertrophy GO:0014896 24 0.022
regulation of myotube differentiation GO:0010830 62 0.022
hindbrain development GO:0030902 128 0.022
cation transmembrane transport GO:0098655 266 0.022
leukocyte homeostasis GO:0001776 79 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.022
lymphocyte proliferation GO:0046651 164 0.022
muscle cell development GO:0055001 133 0.022
lung development GO:0030324 164 0.022
female sex differentiation GO:0046660 84 0.022
regulation of neuron death GO:1901214 134 0.021
positive regulation of response to wounding GO:1903036 66 0.021
myosin filament assembly GO:0031034 2 0.021
spermatogenesis GO:0007283 284 0.021
trunk neural crest cell migration GO:0036484 4 0.021
secretory granule organization GO:0033363 20 0.021
mesodermal cell migration GO:0008078 4 0.021
regulation of peptide transport GO:0090087 91 0.021
positive regulation of secretion GO:0051047 130 0.021
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.021
negative regulation of homeostatic process GO:0032845 71 0.021
regulation of peptide hormone secretion GO:0090276 75 0.021
myeloid leukocyte activation GO:0002274 83 0.021
forebrain cell migration GO:0021885 58 0.021
associative learning GO:0008306 61 0.021
lens development in camera type eye GO:0002088 62 0.021

S1pr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.063
cancer DOID:162 0 0.048
disease of cellular proliferation DOID:14566 0 0.048
organ system cancer DOID:0050686 0 0.048
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.048