Mus musculus

18 known processes

Ptpn4

protein tyrosine phosphatase, non-receptor type 4

(Aliases: TEP,TEP/mPTPMEG,hPTP-MEG,PTPMEG,Ptn4)

Ptpn4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of vesicle mediated transport GO:0060627 139 0.049
cell type specific apoptotic process GO:0097285 268 0.048
spermatogenesis GO:0007283 284 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.045
nitrogen compound transport GO:0071705 271 0.045
cation transport GO:0006812 399 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
ion transmembrane transport GO:0034220 361 0.042
peptidyl amino acid modification GO:0018193 336 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
amine metabolic process GO:0009308 45 0.039
negative regulation of protein metabolic process GO:0051248 282 0.038
dna metabolic process GO:0006259 303 0.037
cellular amine metabolic process GO:0044106 44 0.036
camera type eye development GO:0043010 266 0.036
cellular ketone metabolic process GO:0042180 84 0.035
cellular lipid metabolic process GO:0044255 323 0.035
male gamete generation GO:0048232 285 0.035
adult behavior GO:0030534 135 0.032
regulation of membrane potential GO:0042391 192 0.032
leukocyte differentiation GO:0002521 342 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
regulation of cell activation GO:0050865 289 0.031
cell adhesion GO:0007155 329 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
regulation of neuron differentiation GO:0045664 281 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
immune effector process GO:0002252 321 0.029
heterocycle catabolic process GO:0046700 280 0.028
cation transmembrane transport GO:0098655 266 0.028
carbohydrate metabolic process GO:0005975 230 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.027
regulation of cell cycle GO:0051726 281 0.027
positive regulation of protein modification process GO:0031401 299 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.025
negative regulation of molecular function GO:0044092 258 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
purine containing compound metabolic process GO:0072521 311 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.024
anion transport GO:0006820 177 0.024
sensory perception GO:0007600 245 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
apoptotic signaling pathway GO:0097190 306 0.023
membrane organization GO:0061024 245 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
response to organonitrogen compound GO:0010243 246 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
regulation of homeostatic process GO:0032844 182 0.022
homeostasis of number of cells GO:0048872 210 0.022
regulation of neuron apoptotic process GO:0043523 122 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
cellular response to dna damage stimulus GO:0006974 207 0.022
negative regulation of protein modification process GO:0031400 163 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
inflammatory response GO:0006954 244 0.022
retina development in camera type eye GO:0060041 119 0.022
regulation of leukocyte differentiation GO:1902105 159 0.021
negative regulation of immune system process GO:0002683 209 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
endomembrane system organization GO:0010256 147 0.021
chromatin organization GO:0006325 206 0.021
regulation of secretion GO:0051046 274 0.021
regulation of cellular catabolic process GO:0031329 242 0.020
regulation of protein localization GO:0032880 231 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
regulation of ion transport GO:0043269 215 0.020
regulation of organelle organization GO:0033043 289 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
regulation of kinase activity GO:0043549 249 0.020
neuron death GO:0070997 154 0.020
regulation of ion transmembrane transport GO:0034765 119 0.020
transmission of nerve impulse GO:0019226 76 0.020
gland development GO:0048732 330 0.020
aromatic compound catabolic process GO:0019439 286 0.020
oxidation reduction process GO:0055114 342 0.019
cation homeostasis GO:0055080 212 0.019
organic anion transport GO:0015711 137 0.019
fertilization GO:0009566 127 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
regulation of mapk cascade GO:0043408 248 0.019
regulation of cell migration GO:0030334 219 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
protein ubiquitination GO:0016567 171 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
transmembrane transport GO:0055085 412 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
muscle tissue development GO:0060537 308 0.019
skeletal system development GO:0001501 356 0.019
myeloid cell differentiation GO:0030099 233 0.019
cytoplasmic transport GO:0016482 234 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
regulation of transmembrane transport GO:0034762 128 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
nucleotide metabolic process GO:0009117 332 0.018
carboxylic acid transport GO:0046942 100 0.018
regulation of defense response GO:0031347 233 0.018
peptide transport GO:0015833 133 0.018
synaptic transmission GO:0007268 329 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
methylation GO:0032259 134 0.018
cellular homeostasis GO:0019725 240 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.017
nuclear division GO:0000280 158 0.017
spermatid development GO:0007286 108 0.017
regulation of secretion by cell GO:1903530 249 0.017
ras protein signal transduction GO:0007265 77 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
germ cell development GO:0007281 185 0.017
positive regulation of cell death GO:0010942 224 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
amide transport GO:0042886 138 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
fat cell differentiation GO:0045444 160 0.017
protein localization to membrane GO:0072657 108 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
calcium ion transport GO:0006816 159 0.016
wnt signaling pathway GO:0016055 188 0.016
glycoprotein metabolic process GO:0009100 116 0.016
t cell activation GO:0042110 289 0.016
macromolecule catabolic process GO:0009057 281 0.016
tissue homeostasis GO:0001894 115 0.016
neuron apoptotic process GO:0051402 142 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
plasma membrane organization GO:0007009 90 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
adaptive immune response GO:0002250 155 0.016
sensory organ morphogenesis GO:0090596 242 0.016
mapk cascade GO:0000165 281 0.016
cellular protein complex assembly GO:0043623 116 0.016
skeletal muscle organ development GO:0060538 163 0.016
response to lipopolysaccharide GO:0032496 128 0.016
organophosphate catabolic process GO:0046434 232 0.016
blood vessel morphogenesis GO:0048514 285 0.016
urogenital system development GO:0001655 261 0.016
stem cell differentiation GO:0048863 268 0.016
mrna metabolic process GO:0016071 84 0.016
peptidyl serine modification GO:0018209 83 0.016
respiratory system development GO:0060541 190 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.016
spermatid differentiation GO:0048515 115 0.016
locomotory behavior GO:0007626 195 0.016
single organism cell adhesion GO:0098602 156 0.016
compound eye development GO:0048749 1 0.016
renal system development GO:0072001 225 0.015
negative regulation of kinase activity GO:0033673 81 0.015
regulation of inflammatory response GO:0050727 147 0.015
nucleoside metabolic process GO:0009116 246 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
epithelial cell development GO:0002064 159 0.015
regulation of cell cycle process GO:0010564 160 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
organelle fission GO:0048285 170 0.015
nucleoside catabolic process GO:0009164 206 0.015
protein localization to organelle GO:0033365 185 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
cytokine production GO:0001816 319 0.015
regulation of protein kinase activity GO:0045859 232 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
protein maturation GO:0051604 176 0.015
cell activation involved in immune response GO:0002263 126 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
hexose metabolic process GO:0019318 98 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
intracellular protein transport GO:0006886 204 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
regulation of cell projection organization GO:0031344 206 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
regulation of cytokine production GO:0001817 266 0.015
muscle cell differentiation GO:0042692 261 0.014
anatomical structure homeostasis GO:0060249 145 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
positive regulation of transferase activity GO:0051347 167 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
regulation of neuron death GO:1901214 134 0.014
response to peptide hormone GO:0043434 127 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
membrane depolarization GO:0051899 64 0.014
regulation of neuron projection development GO:0010975 169 0.014
leukocyte migration GO:0050900 124 0.014
cognition GO:0050890 149 0.014
cellular response to lipid GO:0071396 145 0.014
regulation of cell motility GO:2000145 236 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
nucleotide catabolic process GO:0009166 217 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
kidney development GO:0001822 213 0.014
neural tube development GO:0021915 160 0.014
regulation of hydrolase activity GO:0051336 246 0.014
response to insulin GO:0032868 100 0.014
neuromuscular process GO:0050905 99 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
maintenance of location GO:0051235 89 0.014
lymphocyte proliferation GO:0046651 164 0.014
meiotic cell cycle GO:0051321 122 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
developmental maturation GO:0021700 193 0.014
cellular response to peptide GO:1901653 92 0.013
negative regulation of cell cycle GO:0045786 123 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
sequestering of calcium ion GO:0051208 18 0.013
response to organic cyclic compound GO:0014070 198 0.013
protein processing GO:0016485 163 0.013
regulation of protein processing GO:0070613 96 0.013
hindbrain development GO:0030902 128 0.013
covalent chromatin modification GO:0016569 163 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
lipid biosynthetic process GO:0008610 179 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
glycerolipid metabolic process GO:0046486 122 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
protein glycosylation GO:0006486 55 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of proteolysis GO:0030162 164 0.013
regulation of intracellular transport GO:0032386 159 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
divalent inorganic cation transport GO:0072511 178 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
forebrain development GO:0030900 302 0.013
regulation of transferase activity GO:0051338 263 0.013
dna recombination GO:0006310 92 0.013
regulation of cell adhesion GO:0030155 154 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
histone modification GO:0016570 159 0.013
inorganic cation transmembrane transport GO:0098662 207 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
meiotic nuclear division GO:0007126 115 0.012
positive regulation of cell activation GO:0050867 158 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
glucose homeostasis GO:0042593 128 0.012
protein localization to nucleus GO:0034504 121 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
rna interference GO:0016246 2 0.012
organic acid biosynthetic process GO:0016053 86 0.012
regulation of t cell activation GO:0050863 170 0.012
negative regulation of transferase activity GO:0051348 85 0.012
positive regulation of growth GO:0045927 104 0.012
nuclear transport GO:0051169 139 0.012
wound healing GO:0042060 157 0.012
response to peptide GO:1901652 136 0.012
lymphocyte differentiation GO:0030098 242 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
multicellular organismal signaling GO:0035637 91 0.012
fatty acid metabolic process GO:0006631 121 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
innate immune response GO:0045087 157 0.012
gliogenesis GO:0042063 141 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.012
peptide hormone secretion GO:0030072 109 0.012
response to radiation GO:0009314 165 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of endocytosis GO:0030100 69 0.012
organic acid transport GO:0015849 101 0.012
placenta development GO:0001890 140 0.012
angiogenesis GO:0001525 201 0.012
ossification GO:0001503 216 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
male genitalia morphogenesis GO:0048808 4 0.012
positive regulation of cytokine production GO:0001819 174 0.011
blood circulation GO:0008015 195 0.011
regulation of protein complex assembly GO:0043254 83 0.011
regulation of cellular response to stress GO:0080135 159 0.011
small molecule biosynthetic process GO:0044283 132 0.011
regulation of protein maturation GO:1903317 96 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
cellular ion homeostasis GO:0006873 165 0.011
myeloid cell homeostasis GO:0002262 114 0.011
mitotic cell cycle process GO:1903047 159 0.011
cell growth GO:0016049 130 0.011
negative regulation of nervous system development GO:0051961 156 0.011
multicellular organism growth GO:0035264 161 0.011
respiratory tube development GO:0030323 167 0.011
endocytosis GO:0006897 168 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
organelle assembly GO:0070925 177 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
learning or memory GO:0007611 148 0.011
regulation of hormone secretion GO:0046883 88 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
chromatin modification GO:0016568 187 0.011
sequestering of metal ion GO:0051238 19 0.011
b cell activation GO:0042113 161 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.011
ear development GO:0043583 200 0.011
regulation of response to wounding GO:1903034 189 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
dephosphorylation GO:0016311 129 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
striated muscle tissue development GO:0014706 293 0.011
negative regulation of organelle organization GO:0010639 90 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
macromolecule methylation GO:0043414 120 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
negative regulation of proteolysis GO:0045861 74 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
muscle contraction GO:0006936 101 0.010
cellular chemical homeostasis GO:0055082 215 0.010
leukocyte mediated immunity GO:0002443 174 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
rna processing GO:0006396 105 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
oocyte construction GO:0007308 2 0.010
lipid modification GO:0030258 65 0.010
cellular protein catabolic process GO:0044257 155 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
mitotic cell cycle GO:0000278 195 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
stem cell development GO:0048864 219 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
metencephalon development GO:0022037 89 0.010
skeletal system morphogenesis GO:0048705 203 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
regulation of ion transmembrane transporter activity GO:0032412 54 0.010
regulation of ossification GO:0030278 112 0.010
positive regulation of leukocyte differentiation GO:1902107 86 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
neural tube formation GO:0001841 108 0.010
regulation of striated muscle cell differentiation GO:0051153 81 0.010
protein polymerization GO:0051258 57 0.010
synapsis GO:0007129 34 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
organelle localization GO:0051640 179 0.010
heart morphogenesis GO:0003007 178 0.010
calcium ion homeostasis GO:0055074 127 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
regulation of protein catabolic process GO:0042176 108 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.010
insulin secretion GO:0030073 89 0.010
metal ion homeostasis GO:0055065 189 0.010

Ptpn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
immune system disease DOID:2914 0 0.023
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
hematopoietic system disease DOID:74 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.011
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011