|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.994
|
Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.993
|
Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.990
|
Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.990
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.988
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.987
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.987
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.985
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.982
|
Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.977
|
Yeast Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.965
|
Fly |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.964
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.951
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.938
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.935
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.926
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.924
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.922
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
0.912
|
Yeast |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.901
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.894
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.889
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.859
|
Mouse |
|
|
lung development
|
GO:0030324 |
164 |
0.857
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.850
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.850
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.836
|
Fly |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.819
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.798
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.790
|
Human Mouse |
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.781
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.777
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.777
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.765
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.753
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.741
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.739
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.739
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.735
|
Yeast Rat |
|
|
regulation of nuclear cell cycle dna replication
|
GO:0033262 |
2 |
0.725
|
Yeast |
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.716
|
Yeast |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.705
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.704
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.692
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.692
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.691
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.686
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.684
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.683
|
Mouse |
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.683
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.674
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.674
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.670
|
Mouse |
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.669
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.668
|
|
|
|
jun phosphorylation
|
GO:0007258 |
41 |
0.667
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.663
|
Fly |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.662
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.656
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.654
|
Mouse |
|
|
vesicle localization
|
GO:0051648 |
86 |
0.650
|
Worm |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.641
|
Mouse |
|
|
connective tissue development
|
GO:0061448 |
179 |
0.635
|
Mouse |
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.634
|
Yeast |
|
|
axon guidance
|
GO:0007411 |
141 |
0.634
|
Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.633
|
Fly |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.622
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.617
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.615
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.611
|
|
|
|
maternal placenta development
|
GO:0001893 |
20 |
0.607
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.602
|
Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.597
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.594
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.589
|
Worm |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.581
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.578
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.578
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.575
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.574
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.572
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.572
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.567
|
Fly |
|
|
nuclear division
|
GO:0000280 |
158 |
0.549
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.520
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.517
|
Mouse |
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.513
|
Yeast |
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.506
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.505
|
Human Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.503
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.500
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.492
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.492
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.490
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.486
|
Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.480
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.477
|
Fly |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.475
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.474
|
Yeast |
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.472
|
|
|
|
radial glia guided migration of purkinje cell
|
GO:0021942 |
6 |
0.464
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.464
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.454
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.452
|
Mouse |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.446
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.443
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.439
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.425
|
Fly |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.425
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.420
|
Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.414
|
Mouse |
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.414
|
Yeast Rat |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.414
|
Mouse |
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.409
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.408
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.405
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.405
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.404
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.404
|
Fly |
|
|
positive regulation of transforming growth factor beta2 production
|
GO:0032915 |
2 |
0.401
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.400
|
Worm |
|
|
forebrain development
|
GO:0030900 |
302 |
0.400
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.399
|
|
|
|
monocyte differentiation
|
GO:0030224 |
9 |
0.398
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.396
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.395
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.392
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.389
|
Fly |
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.379
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.378
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.369
|
Worm |
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.364
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.364
|
Mouse |
|
|
response to metal ion
|
GO:0010038 |
47 |
0.362
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.360
|
Human |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.359
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.354
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.353
|
Fly |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.353
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.352
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.349
|
Rat |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.339
|
Human Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.339
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.339
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.336
|
Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.331
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.331
|
Mouse |
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.330
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.329
|
Mouse |
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.325
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.321
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.321
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
57 |
0.318
|
Fly |
|
|
maternal process involved in female pregnancy
|
GO:0060135 |
32 |
0.316
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.316
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.311
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.307
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.303
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.303
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.300
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.298
|
Mouse |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.297
|
Fly |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.292
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.289
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.288
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.287
|
|
|
|
cartilage condensation
|
GO:0001502 |
18 |
0.286
|
Mouse |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.282
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.279
|
Mouse Fly |
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.275
|
Fly |
|
|
osmosensory signaling pathway
|
GO:0007231 |
1 |
0.273
|
Yeast |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.272
|
Fly |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.265
|
Human Mouse |
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.265
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.263
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.262
|
Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.261
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.260
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.260
|
Fly |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.260
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.260
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.260
|
Yeast |
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.256
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.252
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.251
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.250
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.248
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.246
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.245
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.245
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.245
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.244
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.243
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.243
|
Fly |
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.241
|
Yeast Rat Worm |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.238
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.237
|
Human Rat |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.237
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.235
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.233
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.232
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.231
|
Mouse |
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.230
|
Mouse |
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.230
|
Human |
|
|
positive regulation of autophagy
|
GO:0010508 |
9 |
0.228
|
Fly |
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.225
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.224
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.222
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.219
|
Fly |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.218
|
Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.218
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.216
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.216
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.216
|
Mouse |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.216
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.214
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.212
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.211
|
Human Fly |
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.208
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.207
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.207
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.206
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.206
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.205
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.204
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.204
|
Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.202
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.202
|
Fly |
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.202
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.201
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.200
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.199
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.195
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.194
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.192
|
Mouse |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.192
|
Human Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.191
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.190
|
|
|
|
embryonic process involved in female pregnancy
|
GO:0060136 |
7 |
0.190
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.189
|
Mouse |
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.189
|
Human |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.189
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.183
|
|
|
|
osteoblast development
|
GO:0002076 |
17 |
0.181
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.180
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.180
|
Mouse |
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.178
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.176
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.176
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.174
|
|
|
|
protein homooligomerization
|
GO:0051260 |
43 |
0.173
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.173
|
Fly |
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.173
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.172
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.171
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.170
|
Human Yeast |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.169
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.168
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.166
|
Mouse Fly |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.166
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.164
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.163
|
Human Mouse |
|
|
protein processing
|
GO:0016485 |
163 |
0.163
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.163
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.163
|
Human |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.162
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.161
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.161
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.161
|
Mouse |
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.160
|
Yeast Worm |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.160
|
Rat |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.159
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.159
|
|
|
|
cellular response to calcium ion
|
GO:0071277 |
14 |
0.158
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.158
|
Mouse |
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.157
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
43 |
0.156
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.156
|
|
|
|
cellular response to cadmium ion
|
GO:0071276 |
3 |
0.155
|
Fly |
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.155
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.154
|
|
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.152
|
Mouse |
|
|
response to arsenic containing substance
|
GO:0046685 |
5 |
0.149
|
Yeast Fly |
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.149
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.148
|
|
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.148
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.146
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.143
|
Mouse |
|
|
regulation of protein homodimerization activity
|
GO:0043496 |
4 |
0.142
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.141
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.141
|
Rat |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.140
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.140
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.139
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.138
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.136
|
|
|
|
regulation of brown fat cell differentiation
|
GO:0090335 |
5 |
0.135
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.134
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.134
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.134
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.133
|
|
|
|
transforming growth factor beta2 production
|
GO:0032906 |
2 |
0.133
|
|
|
|
mating
|
GO:0007618 |
27 |
0.133
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.132
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.131
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.131
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.130
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.129
|
Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.128
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.127
|
Fly |
|
|
autophagy
|
GO:0006914 |
45 |
0.125
|
Fly |
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.124
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.123
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.122
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.121
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.121
|
|
|
|
translation
|
GO:0006412 |
93 |
0.121
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.120
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.120
|
Rat |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.120
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.119
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.118
|
Mouse |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.118
|
Mouse |
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.116
|
|
|
|
cellular response to osmotic stress
|
GO:0071470 |
7 |
0.115
|
Yeast |
|
|
digestive system development
|
GO:0055123 |
200 |
0.115
|
Fly |
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.114
|
Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.114
|
Rat |
|
|
meiosis i
|
GO:0007127 |
60 |
0.113
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.113
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.113
|
Mouse |
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.112
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.112
|
|
|
|
learning
|
GO:0007612 |
98 |
0.111
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.109
|
Mouse |
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.108
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.108
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.107
|
|
|
|
nuclear dna replication
|
GO:0033260 |
3 |
0.107
|
Yeast |
|
|
lipid modification
|
GO:0030258 |
65 |
0.106
|
Mouse |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.105
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.105
|
Human |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.104
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.104
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.103
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.103
|
Mouse |
|
|
regulation of synapse structural plasticity
|
GO:0051823 |
4 |
0.102
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.102
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.101
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.101
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.100
|
Rat |
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.100
|
Mouse |
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.099
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.099
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.099
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.099
|
Fly |
|
|
appendage development
|
GO:0048736 |
166 |
0.098
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.098
|
|
|
|
cellular response to drug
|
GO:0035690 |
15 |
0.098
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.098
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.097
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.097
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.097
|
Human |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.096
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.095
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.095
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.094
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.093
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.092
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.092
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.091
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.091
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.091
|
Worm |
|
|
neuron death
|
GO:0070997 |
154 |
0.090
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.090
|
|
|
|
cellular response to reactive nitrogen species
|
GO:1902170 |
5 |
0.090
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.090
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.089
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.089
|
|
|
|
organelle disassembly
|
GO:1903008 |
2 |
0.089
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.089
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.088
|
Fly |
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.088
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.088
|
Rat |
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.087
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.087
|
Mouse |
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.087
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.086
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.086
|
Mouse |
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
23 |
0.086
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.085
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.083
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.083
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.083
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.082
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.082
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.082
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.081
|
Mouse |
|
|
response to cadmium ion
|
GO:0046686 |
8 |
0.081
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.080
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.079
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.079
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.078
|
Rat |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.078
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.078
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.077
|
Mouse |
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.077
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.077
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.077
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.076
|
Human Mouse |
|
|
response to starvation
|
GO:0042594 |
65 |
0.076
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.076
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.076
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.075
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.075
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.075
|
Human |
|
|
mitochondrial membrane organization
|
GO:0007006 |
26 |
0.075
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.074
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.074
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.074
|
Mouse |
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.073
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.073
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
14 |
0.072
|
|
|
|
excretion
|
GO:0007588 |
22 |
0.072
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
19 |
0.072
|
|
|
|
hindbrain radial glia guided cell migration
|
GO:0021932 |
12 |
0.072
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.072
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.071
|
Rat |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.071
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.071
|
|
|
|
decidualization
|
GO:0046697 |
10 |
0.070
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.069
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.069
|
Fly |
|
|
cation transport
|
GO:0006812 |
399 |
0.069
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.069
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.069
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.069
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.069
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.069
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.068
|
Mouse |
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.067
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.067
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.067
|
|
|
|
adipose tissue development
|
GO:0060612 |
25 |
0.067
|
|
|
|
determination of digestive tract left right asymmetry
|
GO:0071907 |
1 |
0.067
|
Fly |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.067
|
Mouse |
|
|
urogenital system development
|
GO:0001655 |
261 |
0.066
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0097201 |
1 |
0.066
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.065
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.065
|
Human |
|
|
t cell activation
|
GO:0042110 |
289 |
0.065
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.065
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.064
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.064
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.064
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.064
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.063
|
Fly |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.063
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.063
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.063
|
|
|
|
stress granule disassembly
|
GO:0035617 |
2 |
0.062
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.062
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.061
|
Mouse |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.061
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.061
|
Human |
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
17 |
0.060
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.060
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.059
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.059
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.059
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.059
|
Fly |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.059
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.059
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.059
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.059
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.059
|
Mouse |
|
|
cellular response to metal ion
|
GO:0071248 |
31 |
0.058
|
Fly |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.058
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.058
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.058
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.058
|
Worm |
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.057
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.057
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.057
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.057
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.057
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.057
|
Human Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.057
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.056
|
Human |
