Mus musculus

70 known processes

Ptges2

prostaglandin E synthase 2

(Aliases: C79137,MGC6845,0610038H10Rik,Pges2,Mpges2,Gbf1)

Ptges2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 134 0.136
epithelial tube morphogenesis GO:0060562 303 0.085
morphogenesis of a branching epithelium GO:0061138 193 0.070
oxidation reduction process GO:0055114 342 0.063
ribose phosphate metabolic process GO:0019693 291 0.052
compound eye development GO:0048749 1 0.050
regulation of feeding behavior GO:0060259 3 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.049
gonad development GO:0008406 141 0.046
positive regulation of hydrolase activity GO:0051345 148 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
nitrogen compound transport GO:0071705 271 0.039
nucleotide metabolic process GO:0009117 332 0.038
purine nucleotide metabolic process GO:0006163 302 0.038
morphogenesis of a branching structure GO:0001763 203 0.035
regulation of secretion by cell GO:1903530 249 0.035
regulation of hormone levels GO:0010817 211 0.035
epithelial cell proliferation GO:0050673 174 0.034
response to oxygen levels GO:0070482 62 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
branching morphogenesis of an epithelial tube GO:0048754 159 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.032
generation of precursor metabolites and energy GO:0006091 103 0.032
rho protein signal transduction GO:0007266 32 0.032
energy derivation by oxidation of organic compounds GO:0015980 77 0.032
negative regulation of cell proliferation GO:0008285 296 0.031
regulation of secretion GO:0051046 274 0.031
lipid biosynthetic process GO:0008610 179 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
sensory perception GO:0007600 245 0.029
transmembrane transport GO:0055085 412 0.029
organophosphate catabolic process GO:0046434 232 0.028
small gtpase mediated signal transduction GO:0007264 97 0.027
response to oxidative stress GO:0006979 123 0.027
regulation of membrane potential GO:0042391 192 0.027
cellular lipid metabolic process GO:0044255 323 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
apoptotic signaling pathway GO:0097190 306 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
gland development GO:0048732 330 0.025
negative regulation of molecular function GO:0044092 258 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
gastrulation GO:0007369 116 0.025
response to organonitrogen compound GO:0010243 246 0.025
heterocycle catabolic process GO:0046700 280 0.024
regulation of hydrolase activity GO:0051336 246 0.024
homeostasis of number of cells GO:0048872 210 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.023
leukocyte differentiation GO:0002521 342 0.023
striated muscle tissue development GO:0014706 293 0.023
male gamete generation GO:0048232 285 0.023
regulation of epithelial cell proliferation GO:0050678 141 0.023
glucose homeostasis GO:0042593 128 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
muscle cell differentiation GO:0042692 261 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
rhythmic process GO:0048511 174 0.022
photoreceptor cell morphogenesis GO:0008594 3 0.022
digestive tract morphogenesis GO:0048546 147 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
multi multicellular organism process GO:0044706 109 0.021
cell maturation GO:0048469 127 0.021
mammary gland epithelium development GO:0061180 65 0.021
digestive tract development GO:0048565 190 0.021
spermatogenesis GO:0007283 284 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
digestive system development GO:0055123 200 0.021
positive regulation of cell development GO:0010720 237 0.021
steroid metabolic process GO:0008202 119 0.020
development of primary sexual characteristics GO:0045137 143 0.020
cellular response to inorganic substance GO:0071241 37 0.020
organonitrogen compound catabolic process GO:1901565 264 0.019
regulation of cellular response to stress GO:0080135 159 0.019
intracellular protein transport GO:0006886 204 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
ovulation cycle GO:0042698 59 0.019
amine metabolic process GO:0009308 45 0.019
skeletal muscle organ development GO:0060538 163 0.019
protein targeting GO:0006605 143 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
female gonad development GO:0008585 71 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
purine containing compound metabolic process GO:0072521 311 0.019
cellular amino acid metabolic process GO:0006520 103 0.019
intracellular receptor signaling pathway GO:0030522 74 0.018
protein localization to organelle GO:0033365 185 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
female sex differentiation GO:0046660 84 0.018
amide transport GO:0042886 138 0.018
developmental maturation GO:0021700 193 0.018
translation GO:0006412 93 0.018
cellular amine metabolic process GO:0044106 44 0.018
activation of adenylate cyclase activity GO:0007190 4 0.017
regulation of reproductive process GO:2000241 66 0.017
cell growth GO:0016049 130 0.017
regulation of organelle organization GO:0033043 289 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
myeloid cell differentiation GO:0030099 233 0.017
response to monosaccharide GO:0034284 67 0.017
positive regulation of proteolysis GO:0045862 85 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
nucleotide catabolic process GO:0009166 217 0.016
cardiac chamber morphogenesis GO:0003206 93 0.016
regulation of mapk cascade GO:0043408 248 0.016
cellular ketone metabolic process GO:0042180 84 0.016
positive regulation of cholesterol homeostasis GO:2000189 2 0.016
development of primary female sexual characteristics GO:0046545 73 0.016
germ cell development GO:0007281 185 0.016
positive regulation of protein modification process GO:0031401 299 0.016
citrate metabolic process GO:0006101 3 0.016
ras protein signal transduction GO:0007265 77 0.016
regulation of morphogenesis of a branching structure GO:0060688 53 0.016
response to organic cyclic compound GO:0014070 198 0.016
muscle tissue development GO:0060537 308 0.016
purine nucleotide catabolic process GO:0006195 211 0.015
mesoderm development GO:0007498 100 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
nucleoside catabolic process GO:0009164 206 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
action potential GO:0001508 78 0.015
inflammatory response GO:0006954 244 0.015
nucleoside metabolic process GO:0009116 246 0.015
response to inorganic substance GO:0010035 96 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
multicellular organism growth GO:0035264 161 0.014
cellular protein complex assembly GO:0043623 116 0.014
skin development GO:0043588 220 0.014
purine containing compound catabolic process GO:0072523 213 0.014
cellular response to lipid GO:0071396 145 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of response to wounding GO:1903034 189 0.014
membrane organization GO:0061024 245 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
aromatic compound catabolic process GO:0019439 286 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
cellular ion homeostasis GO:0006873 165 0.014
cation transport GO:0006812 399 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
carboxylic acid transport GO:0046942 100 0.013
cytokine production GO:0001816 319 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
central nervous system segmentation GO:0035283 3 0.013
regulation of cell projection organization GO:0031344 206 0.013
glycerolipid metabolic process GO:0046486 122 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
lung development GO:0030324 164 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
negative regulation of epithelial cell proliferation GO:0050680 64 0.013
feeding behavior GO:0007631 62 0.013
regulation of cytokine production GO:0001817 266 0.013
protein localization to membrane GO:0072657 108 0.013
response to metal ion GO:0010038 47 0.012
mammary gland lobule development GO:0061377 22 0.012
regulation of peptide transport GO:0090087 91 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
wound healing GO:0042060 157 0.012
regulation of neuron death GO:1901214 134 0.012
mapk cascade GO:0000165 281 0.012
regulation of protein localization GO:0032880 231 0.012
peptide hormone secretion GO:0030072 109 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
response to hypoxia GO:0001666 58 0.012
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.012
regulation of cell motility GO:2000145 236 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
striated muscle cell development GO:0055002 125 0.012
cell type specific apoptotic process GO:0097285 268 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
macromolecule catabolic process GO:0009057 281 0.012
regulation of camp metabolic process GO:0030814 30 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
photoreceptor cell development GO:0042461 40 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
defecation GO:0030421 1 0.011
regulation of anatomical structure size GO:0090066 178 0.011
regulation of neuron differentiation GO:0045664 281 0.011
cellular homeostasis GO:0019725 240 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
cellular respiration GO:0045333 38 0.011
cardiac chamber development GO:0003205 108 0.011
peptidyl amino acid modification GO:0018193 336 0.011
cardiac ventricle development GO:0003231 83 0.011
hormone secretion GO:0046879 128 0.011
bmp signaling pathway GO:0030509 93 0.011
regulation of defense response GO:0031347 233 0.011
regulation of phospholipase c activity GO:1900274 3 0.011
ovarian follicle development GO:0001541 40 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
response to radiation GO:0009314 165 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
multicellular organismal signaling GO:0035637 91 0.011
lymphocyte differentiation GO:0030098 242 0.011
neuron neuron synaptic transmission GO:0007270 69 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
circulatory system process GO:0003013 197 0.011
cytoplasmic transport GO:0016482 234 0.011
epithelial cell development GO:0002064 159 0.010
gliogenesis GO:0042063 141 0.010
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
peptide transport GO:0015833 133 0.010
positive regulation of antimicrobial peptide production GO:0002225 1 0.010
t cell activation GO:0042110 289 0.010
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
muscle cell development GO:0055001 133 0.010
acetylcholine transport GO:0015870 2 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
cation transmembrane transport GO:0098655 266 0.010
regulation of cell activation GO:0050865 289 0.010
cyclic purine nucleotide metabolic process GO:0052652 43 0.010

Ptges2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.046
cancer DOID:162 0 0.024
organ system cancer DOID:0050686 0 0.020
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012