|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.384
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.312
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.305
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.298
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.269
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.269
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.208
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.206
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.199
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.179
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.175
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.173
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.172
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.172
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.163
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.163
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.161
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.157
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.154
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.151
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.144
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.144
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.142
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.139
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.139
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.129
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.124
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.123
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.116
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
15 |
0.115
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.115
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.115
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.114
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.112
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.109
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.109
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.109
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.106
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.105
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.105
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.101
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.100
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.099
|
|
|
|
cytoplasmic microtubule organization
|
GO:0031122 |
14 |
0.097
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.095
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.094
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.090
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.089
|
|
|
|
negative regulation of microtubule polymerization
|
GO:0031115 |
2 |
0.088
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.087
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.086
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.085
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.084
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.083
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.080
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.079
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.078
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.077
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.076
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.076
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.073
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.072
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.071
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.071
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.071
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.070
|
|
|
|
negative regulation of rac protein signal transduction
|
GO:0035021 |
4 |
0.067
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.065
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.063
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.063
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.061
|
|
|
|
regulation of rac protein signal transduction
|
GO:0035020 |
19 |
0.059
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.056
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
13 |
0.055
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.055
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.055
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.050
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.050
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.049
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.049
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.048
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.048
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.045
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.044
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.042
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.037
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.037
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
25 |
0.035
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.034
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.033
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.033
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.031
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.031
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.031
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.030
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.030
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.028
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
7 |
0.027
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.024
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.024
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.023
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.023
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.022
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.021
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.021
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.021
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.020
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.020
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.020
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.020
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.020
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.020
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.020
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.020
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.019
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.019
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.019
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.019
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.019
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.019
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.018
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.018
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.018
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.018
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.018
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.018
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.017
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.017
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.017
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.017
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.017
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.017
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.017
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.017
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.016
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.016
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.016
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.016
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.016
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.016
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.015
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.015
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.015
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.015
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.015
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.015
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.015
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.015
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.015
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.015
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.015
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.015
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.014
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.014
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.014
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.014
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.014
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.014
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.014
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.014
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.013
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.013
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.013
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.013
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.013
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.013
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.013
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.013
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.013
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.013
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.013
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.013
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.013
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.013
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.012
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.012
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.012
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.012
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.012
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.012
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.012
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.012
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.012
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.012
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.012
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.012
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.012
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.012
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.012
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.012
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.012
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.012
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.012
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.012
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.012
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.012
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.012
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.012
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.012
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.012
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.012
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.012
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.011
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.011
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.011
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.011
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.011
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.011
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.011
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.011
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.011
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.011
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.011
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.011
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.011
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.011
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.011
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.011
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.011
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.011
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.011
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.011
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.011
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.011
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.011
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.011
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.011
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.011
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.011
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.011
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.011
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.011
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.011
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.011
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.011
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.010
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.010
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.010
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.010
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.010
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.010
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.010
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.010
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.010
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.010
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.010
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.010
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.010
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.010
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.010
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.010
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.010
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.010
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.010
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.010
|
|