Mus musculus

0 known processes

Eif2d

eukaryotic translation initiation factor 2D

(Aliases: Lgtn,D1Ertd5e)

Eif2d biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound catabolic process GO:0044270 280 0.091
heterocycle catabolic process GO:0046700 280 0.088
apoptotic signaling pathway GO:0097190 306 0.077
organic cyclic compound catabolic process GO:1901361 295 0.075
cellular amino acid metabolic process GO:0006520 103 0.073
cellular response to dna damage stimulus GO:0006974 207 0.066
nucleobase containing small molecule metabolic process GO:0055086 352 0.062
purine containing compound metabolic process GO:0072521 311 0.060
nucleoside phosphate metabolic process GO:0006753 338 0.058
aromatic compound catabolic process GO:0019439 286 0.057
cellular ketone metabolic process GO:0042180 84 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.046
nucleotide catabolic process GO:0009166 217 0.046
glycosyl compound metabolic process GO:1901657 246 0.045
macromolecule catabolic process GO:0009057 281 0.045
nucleotide metabolic process GO:0009117 332 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
purine nucleotide metabolic process GO:0006163 302 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
amine metabolic process GO:0009308 45 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
ribonucleoside metabolic process GO:0009119 245 0.034
positive regulation of cell death GO:0010942 224 0.033
positive regulation of protein modification process GO:0031401 299 0.033
translation GO:0006412 93 0.033
organophosphate catabolic process GO:0046434 232 0.031
purine nucleotide catabolic process GO:0006195 211 0.031
nucleoside phosphate catabolic process GO:1901292 222 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
dna repair GO:0006281 107 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
regulation of cellular response to stress GO:0080135 159 0.028
dna metabolic process GO:0006259 303 0.028
glycosyl compound catabolic process GO:1901658 206 0.028
nucleoside metabolic process GO:0009116 246 0.028
cellular amine metabolic process GO:0044106 44 0.028
nucleoside monophosphate metabolic process GO:0009123 85 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
nucleoside catabolic process GO:0009164 206 0.027
response to oxidative stress GO:0006979 123 0.026
purine ribonucleotide catabolic process GO:0009154 208 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
cytokine production GO:0001816 319 0.025
ribonucleotide catabolic process GO:0009261 208 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
ribonucleoside catabolic process GO:0042454 206 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
positive regulation of interleukin 8 production GO:0032757 2 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
immune effector process GO:0002252 321 0.022
interleukin 8 production GO:0032637 4 0.022
mrna metabolic process GO:0016071 84 0.021
regulation of organelle organization GO:0033043 289 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
regulation of cytokine production GO:0001817 266 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
mapk cascade GO:0000165 281 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
regulation of interleukin 8 production GO:0032677 3 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
purine containing compound catabolic process GO:0072523 213 0.018
regulation of hydrolase activity GO:0051336 246 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
microtubule cytoskeleton organization GO:0000226 157 0.017
regulation of transferase activity GO:0051338 263 0.017
peptidyl amino acid modification GO:0018193 336 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
alpha amino acid metabolic process GO:1901605 59 0.016
microtubule based process GO:0007017 236 0.016
regulation of protein localization GO:0032880 231 0.016
ketone catabolic process GO:0042182 3 0.016
regulation of defense response GO:0031347 233 0.016
regulation of membrane potential GO:0042391 192 0.015
positive regulation of cytokine production GO:0001819 174 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
meiosis i GO:0007127 60 0.015
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
regulation of intracellular transport GO:0032386 159 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
regulation of mapk cascade GO:0043408 248 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
oxidation reduction process GO:0055114 342 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
protein maturation GO:0051604 176 0.015
chromatin organization GO:0006325 206 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
spermatogenesis GO:0007283 284 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
organelle assembly GO:0070925 177 0.014
mitochondrion organization GO:0007005 134 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
locomotory behavior GO:0007626 195 0.014
regulation of kinase activity GO:0043549 249 0.014
establishment of organelle localization GO:0051656 122 0.013
cell type specific apoptotic process GO:0097285 268 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
regulation of response to wounding GO:1903034 189 0.013
regulation of cell cycle GO:0051726 281 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
cytoplasmic transport GO:0016482 234 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
protein processing GO:0016485 163 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
carbohydrate metabolic process GO:0005975 230 0.013
germ cell development GO:0007281 185 0.013
lateral inhibition GO:0046331 1 0.013
atp catabolic process GO:0006200 55 0.013
inflammatory response GO:0006954 244 0.013
small molecule biosynthetic process GO:0044283 132 0.012
male gamete generation GO:0048232 285 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
hatching GO:0035188 4 0.012
maintenance of location GO:0051235 89 0.012
organic acid biosynthetic process GO:0016053 86 0.012
leukocyte mediated immunity GO:0002443 174 0.012
striated muscle tissue development GO:0014706 293 0.012
response to organonitrogen compound GO:0010243 246 0.012
ras protein signal transduction GO:0007265 77 0.012
positive regulation of transferase activity GO:0051347 167 0.012
t cell activation GO:0042110 289 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
regulation of protein transport GO:0051223 163 0.012
aldehyde catabolic process GO:0046185 4 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.012
wnt signaling pathway GO:0016055 188 0.012
organelle fission GO:0048285 170 0.012
regulation of protein catabolic process GO:0042176 108 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
cellular homeostasis GO:0019725 240 0.012
cellular lipid metabolic process GO:0044255 323 0.012
action potential GO:0001508 78 0.011
regulation of protein kinase activity GO:0045859 232 0.011
atp metabolic process GO:0046034 75 0.011
nitrogen compound transport GO:0071705 271 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
cellular response to lipid GO:0071396 145 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
response to lipopolysaccharide GO:0032496 128 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
skeletal muscle organ development GO:0060538 163 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
meiotic cell cycle process GO:1903046 77 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
response to inorganic substance GO:0010035 96 0.011
neuron death GO:0070997 154 0.011
transmembrane transport GO:0055085 412 0.011
protein ubiquitination GO:0016567 171 0.011
b cell activation GO:0042113 161 0.011
skin development GO:0043588 220 0.011
muscle tissue development GO:0060537 308 0.011
alpha amino acid biosynthetic process GO:1901607 15 0.011
anatomical structure homeostasis GO:0060249 145 0.011
protein catabolic process GO:0030163 221 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
blastocyst development GO:0001824 80 0.011
multicellular organismal signaling GO:0035637 91 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.010
cell activation involved in immune response GO:0002263 126 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
stem cell differentiation GO:0048863 268 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
cellular response to oxidative stress GO:0034599 76 0.010
leukocyte differentiation GO:0002521 342 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
leukocyte proliferation GO:0070661 172 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
peptidyl serine phosphorylation GO:0018105 74 0.010
negative regulation of protein modification process GO:0031400 163 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
regulation of feeding behavior GO:0060259 3 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
synaptic transmission GO:0007268 329 0.010
regulation of proteolysis GO:0030162 164 0.010
organism emergence from protective structure GO:0071684 4 0.010

Eif2d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
central nervous system disease DOID:331 0 0.020
neurodegenerative disease DOID:1289 0 0.012