Mus musculus

15 known processes

Map4k2

mitogen-activated protein kinase kinase kinase kinase 2

(Aliases: MGC143893,MGC143894,GCK,BL44,AI385662,Rab8ip)

Map4k2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.502
purine ribonucleotide metabolic process GO:0009150 290 0.407
divalent inorganic cation transport GO:0072511 178 0.405
regulation of cellular catabolic process GO:0031329 242 0.390
small gtpase mediated signal transduction GO:0007264 97 0.374
ribonucleoside metabolic process GO:0009119 245 0.352
nucleoside phosphate catabolic process GO:1901292 222 0.349
ribonucleoside catabolic process GO:0042454 206 0.319
nucleoside metabolic process GO:0009116 246 0.302
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.302
regulation of nucleoside metabolic process GO:0009118 130 0.285
nucleoside phosphate metabolic process GO:0006753 338 0.281
glycosyl compound catabolic process GO:1901658 206 0.281
guanosine containing compound metabolic process GO:1901068 144 0.275
cellular nitrogen compound catabolic process GO:0044270 280 0.272
nucleoside catabolic process GO:0009164 206 0.265
purine nucleotide metabolic process GO:0006163 302 0.249
organophosphate catabolic process GO:0046434 232 0.245
carbohydrate derivative catabolic process GO:1901136 231 0.243
nucleotide catabolic process GO:0009166 217 0.239
positive regulation of protein phosphorylation GO:0001934 242 0.233
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.231
actin cytoskeleton organization GO:0030036 220 0.230
axonogenesis GO:0007409 274 0.215
ras protein signal transduction GO:0007265 77 0.214
nucleotide metabolic process GO:0009117 332 0.211
organonitrogen compound catabolic process GO:1901565 264 0.206
response to peptide GO:1901652 136 0.206
Fly
muscle system process GO:0003012 141 0.202
positive regulation of hydrolase activity GO:0051345 148 0.198
nucleoside triphosphate metabolic process GO:0009141 230 0.191
positive regulation of cellular catabolic process GO:0031331 148 0.190
response to organonitrogen compound GO:0010243 246 0.189
Fly
aromatic compound catabolic process GO:0019439 286 0.185
organic cyclic compound catabolic process GO:1901361 295 0.182
purine containing compound catabolic process GO:0072523 213 0.181
purine containing compound metabolic process GO:0072521 311 0.175
ribonucleotide metabolic process GO:0009259 291 0.170
glycosyl compound metabolic process GO:1901657 246 0.168
gtp metabolic process GO:0046039 144 0.161
g protein coupled receptor signaling pathway GO:0007186 243 0.160
calcium ion homeostasis GO:0055074 127 0.159
purine nucleoside triphosphate catabolic process GO:0009146 203 0.158
peptidyl amino acid modification GO:0018193 336 0.155
muscle cell differentiation GO:0042692 261 0.154
positive regulation of protein modification process GO:0031401 299 0.153
Human
ribonucleotide catabolic process GO:0009261 208 0.152
mapk cascade GO:0000165 281 0.148
Human Fly
cell adhesion GO:0007155 329 0.148
cation homeostasis GO:0055080 212 0.147
regulation of purine nucleotide metabolic process GO:1900542 169 0.145
regulation of ion homeostasis GO:2000021 64 0.145
cation transport GO:0006812 399 0.142
histone modification GO:0016570 159 0.142
chromatin modification GO:0016568 187 0.141
purine nucleoside triphosphate metabolic process GO:0009144 226 0.141
positive regulation of nucleoside metabolic process GO:0045979 91 0.140
ribonucleoside triphosphate metabolic process GO:0009199 220 0.139
purine nucleotide catabolic process GO:0006195 211 0.138
regulation of neuron projection development GO:0010975 169 0.136
regulation of gtp catabolic process GO:0033124 113 0.133
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.133
ion transmembrane transport GO:0034220 361 0.130
purine ribonucleoside catabolic process GO:0046130 205 0.129
positive regulation of nucleotide catabolic process GO:0030813 88 0.128
rho protein signal transduction GO:0007266 32 0.128
regulation of metal ion transport GO:0010959 106 0.127
gtp catabolic process GO:0006184 143 0.123
guanosine containing compound catabolic process GO:1901069 144 0.122
inorganic cation transmembrane transport GO:0098662 207 0.121
chemotaxis GO:0006935 247 0.121
angiogenesis GO:0001525 201 0.120
regulation of hydrolase activity GO:0051336 246 0.117
regulation of mapk cascade GO:0043408 248 0.116
Human Fly
purine nucleoside metabolic process GO:0042278 241 0.115
purine nucleoside catabolic process GO:0006152 205 0.114
ribose phosphate metabolic process GO:0019693 291 0.113
regulation of purine nucleotide catabolic process GO:0033121 122 0.112
leukocyte differentiation GO:0002521 342 0.112
regulation of protein kinase activity GO:0045859 232 0.111
Human
divalent metal ion transport GO:0070838 172 0.108
muscle tissue development GO:0060537 308 0.108
sequestering of calcium ion GO:0051208 18 0.105
regulation of nucleotide metabolic process GO:0006140 169 0.104
purine ribonucleoside metabolic process GO:0046128 241 0.102
purine ribonucleotide catabolic process GO:0009154 208 0.102
cell type specific apoptotic process GO:0097285 268 0.101
synaptic transmission GO:0007268 329 0.097
calcium ion transport GO:0006816 159 0.097
positive regulation of gtpase activity GO:0043547 85 0.097
cytokine mediated signaling pathway GO:0019221 115 0.096
cellular ion homeostasis GO:0006873 165 0.095
regulation of vesicle mediated transport GO:0060627 139 0.093
negative regulation of protein metabolic process GO:0051248 282 0.089
cellular chemical homeostasis GO:0055082 215 0.089
regulation of cell cycle GO:0051726 281 0.089
striated muscle tissue development GO:0014706 293 0.088
regulation of cellular amine metabolic process GO:0033238 20 0.087
sensory organ morphogenesis GO:0090596 242 0.086
leukocyte mediated immunity GO:0002443 174 0.086
muscle cell development GO:0055001 133 0.086
regulation of cellular ketone metabolic process GO:0010565 66 0.085
lymphocyte differentiation GO:0030098 242 0.085
regulation of myeloid cell differentiation GO:0045637 96 0.084
cellular ketone metabolic process GO:0042180 84 0.082
divalent inorganic cation homeostasis GO:0072507 138 0.082
negative regulation of protein phosphorylation GO:0001933 126 0.080
peptidyl serine modification GO:0018209 83 0.079
inorganic ion transmembrane transport GO:0098660 234 0.079
regulation of transferase activity GO:0051338 263 0.079
Human
regulation of system process GO:0044057 200 0.079
nucleoside triphosphate catabolic process GO:0009143 205 0.078
blood vessel morphogenesis GO:0048514 285 0.077
regulation of ion transport GO:0043269 215 0.077
sequestering of metal ion GO:0051238 19 0.077
ribonucleoside triphosphate catabolic process GO:0009203 199 0.076
positive regulation of nucleotide metabolic process GO:0045981 114 0.076
protein localization to organelle GO:0033365 185 0.074
regulation of neuron differentiation GO:0045664 281 0.073
germ cell development GO:0007281 185 0.073
negative regulation of cellular protein metabolic process GO:0032269 247 0.072
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.072
cation transmembrane transport GO:0098655 266 0.070
regulation of kinase activity GO:0043549 249 0.070
Human
multicellular organismal homeostasis GO:0048871 164 0.069
amine metabolic process GO:0009308 45 0.069
myeloid cell differentiation GO:0030099 233 0.068
cellular metal ion homeostasis GO:0006875 151 0.068
positive regulation of gtp catabolic process GO:0033126 85 0.068
limb morphogenesis GO:0035108 149 0.068
peptidyl serine phosphorylation GO:0018105 74 0.068
blood circulation GO:0008015 195 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.067
protein maturation GO:0051604 176 0.066
cardiac muscle contraction GO:0060048 32 0.066
microtubule based process GO:0007017 236 0.066
single organismal cell cell adhesion GO:0016337 131 0.065
cytokine production GO:0001816 319 0.065
negative regulation of cellular component organization GO:0051129 194 0.065
single organism cell adhesion GO:0098602 156 0.064
cellular homeostasis GO:0019725 240 0.064
cellular amino acid metabolic process GO:0006520 103 0.064
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.063
cellular lipid metabolic process GO:0044255 323 0.063
myotube differentiation GO:0014902 105 0.062
neuron projection guidance GO:0097485 141 0.061
monocarboxylic acid metabolic process GO:0032787 191 0.060
cellular component assembly involved in morphogenesis GO:0010927 139 0.060
chromatin organization GO:0006325 206 0.060
positive regulation of ras gtpase activity GO:0032320 65 0.060
cell fate commitment GO:0045165 210 0.059
establishment of organelle localization GO:0051656 122 0.057
positive regulation of programmed cell death GO:0043068 218 0.057
Fly
establishment of vesicle localization GO:0051650 81 0.057
cellular divalent inorganic cation homeostasis GO:0072503 127 0.056
regulation of binding GO:0051098 111 0.056
myosin filament organization GO:0031033 3 0.055
t cell differentiation GO:0030217 174 0.055
circulatory system process GO:0003013 197 0.055
lipid modification GO:0030258 65 0.054
rhythmic process GO:0048511 174 0.054
muscle contraction GO:0006936 101 0.053
multi organism behavior GO:0051705 62 0.053
male gamete generation GO:0048232 285 0.053
negative regulation of nervous system development GO:0051961 156 0.053
forebrain development GO:0030900 302 0.052
regulation of protein localization GO:0032880 231 0.052
cellular amine metabolic process GO:0044106 44 0.052
stem cell maintenance GO:0019827 130 0.052
positive regulation of mapk cascade GO:0043410 170 0.051
Human Fly
endocytosis GO:0006897 168 0.051
positive regulation of cell death GO:0010942 224 0.051
Fly
regulation of ras gtpase activity GO:0032318 88 0.051
negative regulation of cell development GO:0010721 169 0.051
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
protein localization to membrane GO:0072657 108 0.051
regulation of locomotion involved in locomotory behavior GO:0090325 1 0.050
skeletal system development GO:0001501 356 0.050
myosin filament assembly GO:0031034 2 0.049
regulation of cellular component biogenesis GO:0044087 181 0.049
organelle localization GO:0051640 179 0.049
macromolecule catabolic process GO:0009057 281 0.049
negative regulation of molecular function GO:0044092 258 0.049
heart process GO:0003015 94 0.049
regulation of heart contraction GO:0008016 77 0.049
camera type eye development GO:0043010 266 0.048
cellular response to cytokine stimulus GO:0071345 189 0.048
regulation of cell projection organization GO:0031344 206 0.048
calcium ion transmembrane transport GO:0070588 85 0.048
defense response to bacterium GO:0042742 119 0.048
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.048
regulation of transmembrane transport GO:0034762 128 0.047
t cell differentiation in thymus GO:0033077 77 0.047
maintenance of location GO:0051235 89 0.047
axon guidance GO:0007411 141 0.047
response to radiation GO:0009314 165 0.046
placenta development GO:0001890 140 0.046
regulation of cellular component size GO:0032535 121 0.046
Fly
positive regulation of rho gtpase activity GO:0032321 41 0.046
wnt signaling pathway GO:0016055 188 0.046
regulation of cell migration GO:0030334 219 0.045
regulation of homeostatic process GO:0032844 182 0.044
cytoplasmic transport GO:0016482 234 0.044
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.044
heterocycle catabolic process GO:0046700 280 0.044
regulation of nucleotide catabolic process GO:0030811 122 0.044
mitotic cell cycle GO:0000278 195 0.044
regulation of response to wounding GO:1903034 189 0.044
negative regulation of neuron differentiation GO:0045665 101 0.043
gland development GO:0048732 330 0.043
regulation of ion transmembrane transporter activity GO:0032412 54 0.043
very long chain fatty acid catabolic process GO:0042760 2 0.043
phospholipid metabolic process GO:0006644 87 0.043
response to insulin GO:0032868 100 0.042
Fly
regulation of defense response GO:0031347 233 0.042
cellular calcium ion homeostasis GO:0006874 119 0.042
skeletal muscle organ development GO:0060538 163 0.042
negative regulation of glycolytic process GO:0045820 4 0.041
regulation of muscle system process GO:0090257 80 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.041
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.041
Human
leukocyte activation involved in immune response GO:0002366 126 0.040
ossification GO:0001503 216 0.040
compound eye development GO:0048749 1 0.040
regulation of protein binding GO:0043393 60 0.039
nuclear division GO:0000280 158 0.039
female mating behavior GO:0060180 8 0.039
response to inactivity GO:0014854 4 0.039
defecation GO:0030421 1 0.038
cellular response to growth factor stimulus GO:0071363 197 0.038
response to molecule of bacterial origin GO:0002237 143 0.038
neural precursor cell proliferation GO:0061351 121 0.038
cellular response to peptide GO:1901653 92 0.038
Fly
organelle fission GO:0048285 170 0.038
mating GO:0007618 27 0.038
dna metabolic process GO:0006259 303 0.037
heart morphogenesis GO:0003007 178 0.037
regulation of muscle contraction GO:0006937 49 0.037
positive regulation of ion transport GO:0043270 65 0.037
sensory perception of touch GO:0050975 2 0.036
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.036
Human
regulation of voltage gated calcium channel activity GO:1901385 4 0.036
regulation of muscle tissue development GO:1901861 97 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
engulfment of apoptotic cell GO:0043652 3 0.036
multi organism reproductive behavior GO:0044705 29 0.035
somitogenesis GO:0001756 69 0.035
rap protein signal transduction GO:0032486 3 0.035
regulation of blood circulation GO:1903522 93 0.035
regulation of engulfment of apoptotic cell GO:1901074 2 0.035
mast cell activation involved in immune response GO:0002279 20 0.035
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.035
stem cell development GO:0048864 219 0.035
actin filament based movement GO:0030048 23 0.034
positive regulation of nervous system development GO:0051962 221 0.034
negative regulation of cell proliferation GO:0008285 296 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.034
leukocyte migration GO:0050900 124 0.034
positive regulation of growth GO:0045927 104 0.034
his purkinje system cell differentiation GO:0060932 2 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
cellular response to dna damage stimulus GO:0006974 207 0.033
regulation of intracellular protein transport GO:0033157 82 0.033
secretory granule localization GO:0032252 3 0.033
regulation of peptidyl serine phosphorylation GO:0033135 39 0.033
regulation of cell cycle process GO:0010564 160 0.032
adult locomotory behavior GO:0008344 91 0.032
regulation of cell motility GO:2000145 236 0.032
regulation of cytoskeleton organization GO:0051493 122 0.032
lateral inhibition GO:0046331 1 0.032
positive regulation of apoptotic cell clearance GO:2000427 3 0.032
regulation of calcium ion transmembrane transport GO:1903169 20 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
regulation of striated muscle cell differentiation GO:0051153 81 0.032
phosphatidylinositol metabolic process GO:0046488 45 0.032
regulation of exocytosis GO:0017157 61 0.032
myeloid leukocyte differentiation GO:0002573 119 0.032
striated muscle cell development GO:0055002 125 0.032
purine nucleoside monophosphate metabolic process GO:0009126 81 0.031
negative regulation of neuron death GO:1901215 98 0.031
cellular protein complex assembly GO:0043623 116 0.031
carbohydrate metabolic process GO:0005975 230 0.031
lipid homeostasis GO:0055088 63 0.031
Fly
nucleoside monophosphate catabolic process GO:0009125 59 0.031
segmentation GO:0035282 93 0.031
regulation of transporter activity GO:0032409 57 0.031
regulation of membrane potential GO:0042391 192 0.031
myeloid leukocyte mediated immunity GO:0002444 42 0.030
regulation of neuron death GO:1901214 134 0.030
ectodermal digestive tract development GO:0007439 1 0.030
protein catabolic process GO:0030163 221 0.030
release of sequestered calcium ion into cytosol GO:0051209 42 0.030
vagus nerve development GO:0021564 3 0.030
cellular carbohydrate metabolic process GO:0044262 119 0.030
protein processing GO:0016485 163 0.030
developmental growth involved in morphogenesis GO:0060560 138 0.030
appendage development GO:0048736 166 0.029
stem cell differentiation GO:0048863 268 0.029
t cell activation GO:0042110 289 0.029
regulation of neurotransmitter transport GO:0051588 35 0.029
renal system development GO:0072001 225 0.029
multi multicellular organism process GO:0044706 109 0.029
negative regulation of homeostatic process GO:0032845 71 0.029
cardiac muscle tissue development GO:0048738 130 0.029
mesodermal cell migration GO:0008078 4 0.029
regulation of anatomical structure size GO:0090066 178 0.029
Fly
intracellular protein transport GO:0006886 204 0.029
exocytosis GO:0006887 121 0.029
cytosolic calcium ion transport GO:0060401 48 0.029
microtubule cytoskeleton organization GO:0000226 157 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
germinal center formation GO:0002467 16 0.028
myeloid leukocyte activation GO:0002274 83 0.028
regulation of cell adhesion GO:0030155 154 0.028
protein polymerization GO:0051258 57 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
immune effector process GO:0002252 321 0.028
morphogenesis of a branching structure GO:0001763 203 0.028
cell activation involved in immune response GO:0002263 126 0.028
cell growth GO:0016049 130 0.028
neuron apoptotic process GO:0051402 142 0.028
positive regulation of cell migration GO:0030335 109 0.028
atp metabolic process GO:0046034 75 0.028
regulation of intracellular transport GO:0032386 159 0.028
regulation of cell division GO:0051302 76 0.028
t cell selection GO:0045058 34 0.028
regulation of stem cell proliferation GO:0072091 78 0.027
neurotransmitter secretion GO:0007269 62 0.027
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.027
homeostasis of number of cells GO:0048872 210 0.027
positive regulation of apoptotic process GO:0043065 217 0.027
Fly
defense response to other organism GO:0098542 197 0.027
ameboidal type cell migration GO:0001667 128 0.027
dendrite development GO:0016358 115 0.027
asymmetric stem cell division GO:0098722 3 0.027
fatty acid transmembrane transport GO:1902001 1 0.027
asymmetric neuroblast division GO:0055059 1 0.027
metal ion homeostasis GO:0055065 189 0.027
response to organic cyclic compound GO:0014070 198 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
neural tube development GO:0021915 160 0.026
leukocyte degranulation GO:0043299 27 0.026
regulation of cell growth GO:0001558 91 0.026
epithelial cell proliferation GO:0050673 174 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
regulation of actin cytoskeleton organization GO:0032956 84 0.026
negative regulation of protein modification process GO:0031400 163 0.026
response to peptide hormone GO:0043434 127 0.026
Fly
cellular protein catabolic process GO:0044257 155 0.026
intrinsic apoptotic signaling pathway GO:0097193 132 0.026
leukocyte homeostasis GO:0001776 79 0.026
response to growth factor GO:0070848 198 0.026
skin development GO:0043588 220 0.026
developmental cell growth GO:0048588 84 0.025
neuron migration GO:0001764 122 0.025
regulation of map kinase activity GO:0043405 120 0.025
Human
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.025
cell division GO:0051301 120 0.025
positive regulation of atpase activity GO:0032781 3 0.025
positive regulation of inflammatory response GO:0050729 47 0.025
oxidation reduction process GO:0055114 342 0.025
glycerolipid metabolic process GO:0046486 122 0.025
neural tube formation GO:0001841 108 0.025
cellular response to biotic stimulus GO:0071216 92 0.025
telencephalon development GO:0021537 186 0.025
cellularization GO:0007349 1 0.025
somite development GO:0061053 81 0.025
myeloid cell activation involved in immune response GO:0002275 34 0.025
vesicle transport along microtubule GO:0047496 9 0.025
neurotransmitter transport GO:0006836 76 0.024
retina morphogenesis in camera type eye GO:0060042 45 0.024
respiratory system development GO:0060541 190 0.024
myotube cell development GO:0014904 60 0.024
regulation of protein transport GO:0051223 163 0.024
transmembrane transport GO:0055085 412 0.024
positive regulation of transferase activity GO:0051347 167 0.024
Human
regulation of endocytosis GO:0030100 69 0.024
actin filament organization GO:0007015 113 0.024
cognition GO:0050890 149 0.024
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.024
sensory perception GO:0007600 245 0.024
oogenesis GO:0048477 56 0.024
stem cell proliferation GO:0072089 117 0.024
cardiac muscle tissue morphogenesis GO:0055008 44 0.024
epithelial tube morphogenesis GO:0060562 303 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
regulation of organelle organization GO:0033043 289 0.023
microtubule based movement GO:0007018 84 0.023
appendage morphogenesis GO:0035107 149 0.023
striated muscle myosin thick filament assembly GO:0071688 1 0.023
lymphocyte mediated immunity GO:0002449 139 0.023
urogenital system development GO:0001655 261 0.023
nucleoside monophosphate metabolic process GO:0009123 85 0.023
regulation of cytoplasmic transport GO:1903649 112 0.023
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.023
response to inorganic substance GO:0010035 96 0.023
regulation of calcium ion transport GO:0051924 69 0.023
calcium ion transport into cytosol GO:0060402 48 0.023
mitotic nuclear division GO:0007067 48 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
cellular response to insulin stimulus GO:0032869 78 0.022
Fly
negative regulation of cyclase activity GO:0031280 1 0.022
regulation of striated muscle contraction GO:0006942 25 0.022
locomotory behavior GO:0007626 195 0.022
primary neural tube formation GO:0014020 95 0.022
cytosolic calcium ion homeostasis GO:0051480 70 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
response to light stimulus GO:0009416 135 0.022
ribonucleoside monophosphate catabolic process GO:0009158 57 0.022
response to drug GO:0042493 75 0.022
ribonucleoside monophosphate metabolic process GO:0009161 80 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
Human
pharynx development GO:0060465 1 0.022
membrane organization GO:0061024 245 0.022
glial cell differentiation GO:0010001 131 0.022
regulation of rho gtpase activity GO:0032319 58 0.022
muscle fiber development GO:0048747 76 0.022
regulation of secretion by cell GO:1903530 249 0.021
apoptotic signaling pathway GO:0097190 306 0.021
branching morphogenesis of an epithelial tube GO:0048754 159 0.021
cellular response to drug GO:0035690 15 0.021
anatomical structure homeostasis GO:0060249 145 0.021
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade GO:0038168 1 0.021
nuclear transport GO:0051169 139 0.021
skeletal muscle fiber development GO:0048741 58 0.021
endodermal cell fate specification GO:0001714 4 0.021
protein targeting GO:0006605 143 0.021
fatty acid metabolic process GO:0006631 121 0.021
inflammatory response GO:0006954 244 0.021
male courtship behavior GO:0008049 2 0.021
regulation of neurotransmitter levels GO:0001505 87 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
synaptic vesicle transport GO:0048489 57 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
mating behavior GO:0007617 20 0.021
purine nucleoside monophosphate catabolic process GO:0009128 58 0.021
protein localization to nucleus GO:0034504 121 0.021
peptidyl threonine phosphorylation GO:0018107 31 0.020
lens development in camera type eye GO:0002088 62 0.020
regulation of ion transmembrane transport GO:0034765 119 0.020
female gamete generation GO:0007292 74 0.020
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.020
limb development GO:0060173 166 0.020
actomyosin structure organization GO:0031032 56 0.020
response to lipopolysaccharide GO:0032496 128 0.020
mesenchymal cell development GO:0014031 93 0.020
vagus nerve morphogenesis GO:0021644 2 0.020
sensory perception of mechanical stimulus GO:0050954 107 0.019
tissue remodeling GO:0048771 102 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
Fly
protein localization to plasma membrane GO:0072659 57 0.019
olfactory bulb development GO:0021772 30 0.019
positive regulation of intracellular transport GO:0032388 70 0.019
organic anion transport GO:0015711 137 0.019
camp metabolic process GO:0046058 40 0.019
mitotic cell cycle process GO:1903047 159 0.019
lung development GO:0030324 164 0.019
lipid biosynthetic process GO:0008610 179 0.019
neuromuscular process GO:0050905 99 0.019
regulation of neural precursor cell proliferation GO:2000177 70 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
response to acid chemical GO:0001101 111 0.019
positive regulation of engulfment of apoptotic cell GO:1901076 1 0.019
negative regulation of cell adhesion GO:0007162 45 0.018
retina development in camera type eye GO:0060041 119 0.018
regulation of cellular response to stress GO:0080135 159 0.018
Human Fly
blastocyst development GO:0001824 80 0.018
monosaccharide metabolic process GO:0005996 106 0.018
macromolecule methylation GO:0043414 120 0.018
spinal cord development GO:0021510 81 0.018
regulation of myeloid leukocyte differentiation GO:0002761 58 0.018
gene silencing GO:0016458 38 0.018
developmental maturation GO:0021700 193 0.018
cellular response to lipopolysaccharide GO:0071222 77 0.018
carbohydrate catabolic process GO:0016052 32 0.018
spermatogenesis GO:0007283 284 0.018
neuron projection extension GO:1990138 64 0.018
establishment of protein localization to membrane GO:0090150 54 0.018
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.018
establishment or maintenance of cell polarity GO:0007163 86 0.018
multicellular organismal aging GO:0010259 24 0.018
carbohydrate homeostasis GO:0033500 128 0.018
cellular response to acid chemical GO:0071229 68 0.018
glucose homeostasis GO:0042593 128 0.018
mesenchyme development GO:0060485 152 0.018
central nervous system neuron differentiation GO:0021953 162 0.018
adult behavior GO:0030534 135 0.018
Fly
amide transport GO:0042886 138 0.018
phosphorylated carbohydrate dephosphorylation GO:0046838 4 0.018
protein import into nucleus GO:0006606 95 0.018

Map4k2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
disease of metabolism DOID:0014667 0 0.020