Mus musculus

0 known processes

Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

(Aliases: 4432415E19Rik,KHS,GCKR,MAPKKKK5)

Map4k5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 133 0.243
modification dependent protein catabolic process GO:0019941 133 0.187
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.156
proteasomal protein catabolic process GO:0010498 98 0.148
cellular macromolecule catabolic process GO:0044265 206 0.145
regulation of cellular ketone metabolic process GO:0010565 66 0.119
actin cytoskeleton organization GO:0030036 220 0.117
protein modification by small protein conjugation or removal GO:0070647 207 0.115
cellular protein catabolic process GO:0044257 155 0.113
ubiquitin dependent protein catabolic process GO:0006511 129 0.096
establishment of organelle localization GO:0051656 122 0.096
Mouse
cellular ketone metabolic process GO:0042180 84 0.090
transmembrane transport GO:0055085 412 0.087
response to light stimulus GO:0009416 135 0.087
muscle cell differentiation GO:0042692 261 0.086
mitotic cell cycle GO:0000278 195 0.081
negative regulation of immune system process GO:0002683 209 0.078
protein catabolic process GO:0030163 221 0.076
compound eye development GO:0048749 1 0.072
regulation of cellular response to stress GO:0080135 159 0.071
Fly
regulation of cell cycle GO:0051726 281 0.070
cell adhesion GO:0007155 329 0.070
regulation of cell activation GO:0050865 289 0.068
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.067
microtubule based process GO:0007017 236 0.066
actin filament organization GO:0007015 113 0.066
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.065
regulation of engulfment of apoptotic cell GO:1901074 2 0.065
positive regulation of protein phosphorylation GO:0001934 242 0.062
rhythmic process GO:0048511 174 0.059
ras protein signal transduction GO:0007265 77 0.059
camera type eye development GO:0043010 266 0.059
organelle assembly GO:0070925 177 0.056
protein ubiquitination GO:0016567 171 0.056
cation transport GO:0006812 399 0.055
microtubule cytoskeleton organization GO:0000226 157 0.055
peptidyl amino acid modification GO:0018193 336 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
protein autophosphorylation GO:0046777 61 0.053
mitotic cell cycle process GO:1903047 159 0.052
organelle fission GO:0048285 170 0.052
axonogenesis GO:0007409 274 0.051
apoptotic signaling pathway GO:0097190 306 0.051
negative regulation of molecular function GO:0044092 258 0.051
dephosphorylation GO:0016311 129 0.050
macromolecule catabolic process GO:0009057 281 0.050
cellular amine metabolic process GO:0044106 44 0.049
myotube differentiation GO:0014902 105 0.048
forebrain development GO:0030900 302 0.048
protein modification by small protein removal GO:0070646 21 0.048
cellular amino acid metabolic process GO:0006520 103 0.048
chromatin modification GO:0016568 187 0.047
body morphogenesis GO:0010171 45 0.046
regulation of cell motility GO:2000145 236 0.045
cell division GO:0051301 120 0.045
mapk cascade GO:0000165 281 0.043
Fly
maintenance of location GO:0051235 89 0.042
organophosphate catabolic process GO:0046434 232 0.041
membrane organization GO:0061024 245 0.041
single organism cell adhesion GO:0098602 156 0.041
positive regulation of protein modification process GO:0031401 299 0.040
amine metabolic process GO:0009308 45 0.039
regulation of cell adhesion GO:0030155 154 0.039
organelle localization GO:0051640 179 0.039
Mouse
monosaccharide metabolic process GO:0005996 106 0.039
ion transmembrane transport GO:0034220 361 0.039
retina development in camera type eye GO:0060041 119 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.038
regulation of lymphocyte activation GO:0051249 240 0.038
establishment or maintenance of cell polarity GO:0007163 86 0.037
positive regulation of cell death GO:0010942 224 0.037
Fly
protein localization to organelle GO:0033365 185 0.037
leukocyte differentiation GO:0002521 342 0.037
sensory organ morphogenesis GO:0090596 242 0.037
covalent chromatin modification GO:0016569 163 0.037
cell cell junction organization GO:0045216 72 0.037
regulation of cell projection organization GO:0031344 206 0.037
leukocyte migration GO:0050900 124 0.036
regulation of cellular component biogenesis GO:0044087 181 0.036
muscle tissue development GO:0060537 308 0.036
immune effector process GO:0002252 321 0.036
positive regulation of programmed cell death GO:0043068 218 0.036
Fly
nucleoside triphosphate metabolic process GO:0009141 230 0.036
negative regulation of cell proliferation GO:0008285 296 0.036
peptidyl threonine phosphorylation GO:0018107 31 0.036
lymphocyte differentiation GO:0030098 242 0.035
negative regulation of defense response GO:0031348 77 0.035
regulation of cellular component size GO:0032535 121 0.035
Fly
regulation of mitotic sister chromatid segregation GO:0033047 12 0.035
transmission of nerve impulse GO:0019226 76 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
positive regulation of cellular catabolic process GO:0031331 148 0.035
neural tube development GO:0021915 160 0.034
hexose metabolic process GO:0019318 98 0.034
circadian rhythm GO:0007623 114 0.034
negative regulation of cellular amine metabolic process GO:0033239 1 0.034
positive regulation of gtpase activity GO:0043547 85 0.034
striated muscle tissue development GO:0014706 293 0.034
regulation of intracellular protein transport GO:0033157 82 0.033
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.033
regulation of defense response GO:0031347 233 0.033
adaptive immune response GO:0002250 155 0.033
regulation of protein kinase activity GO:0045859 232 0.033
regulation of organelle organization GO:0033043 289 0.033
calcium ion transport GO:0006816 159 0.032
purine containing compound metabolic process GO:0072521 311 0.032
regulation of isoprenoid metabolic process GO:0019747 1 0.032
negative regulation of protein phosphorylation GO:0001933 126 0.032
positive regulation of apoptotic signaling pathway GO:2001235 95 0.032
chromatin organization GO:0006325 206 0.031
response to organonitrogen compound GO:0010243 246 0.031
Fly
phagocytosis GO:0006909 66 0.031
regulation of actin cytoskeleton organization GO:0032956 84 0.031
cardiac muscle tissue development GO:0048738 130 0.031
cellular lipid metabolic process GO:0044255 323 0.031
intracellular protein transport GO:0006886 204 0.031
regulation of gtp catabolic process GO:0033124 113 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
neural precursor cell proliferation GO:0061351 121 0.030
wnt signaling pathway GO:0016055 188 0.030
regulation of neuron differentiation GO:0045664 281 0.030
peptidyl tyrosine phosphorylation GO:0018108 143 0.030
peptidyl threonine modification GO:0018210 31 0.030
action potential GO:0001508 78 0.030
protein modification by small protein conjugation GO:0032446 187 0.030
defense response to other organism GO:0098542 197 0.029
negative regulation of intracellular signal transduction GO:1902532 167 0.029
embryonic epithelial tube formation GO:0001838 130 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
t cell activation GO:0042110 289 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
protein polymerization GO:0051258 57 0.029
cellular protein complex assembly GO:0043623 116 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
response to radiation GO:0009314 165 0.028
response to uv GO:0009411 44 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
Fly
regulation of cell cycle process GO:0010564 160 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
cellular response to peptide hormone stimulus GO:0071375 92 0.028
Fly
purine containing compound catabolic process GO:0072523 213 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
cellular response to insulin stimulus GO:0032869 78 0.028
Fly
chromosome segregation GO:0007059 48 0.027
regulation of interleukin 10 secretion GO:2001179 4 0.027
stem cell differentiation GO:0048863 268 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
nucleotide metabolic process GO:0009117 332 0.027
regulation of neuron projection development GO:0010975 169 0.027
nucleoside catabolic process GO:0009164 206 0.027
developmental growth involved in morphogenesis GO:0060560 138 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
cellular response to cytokine stimulus GO:0071345 189 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
lateral inhibition GO:0046331 1 0.026
regulation of ion transmembrane transport GO:0034765 119 0.026
chemotaxis GO:0006935 247 0.026
oocyte construction GO:0007308 2 0.026
microtubule organizing center organization GO:0031023 28 0.025
neuron projection guidance GO:0097485 141 0.025
protein depolymerization GO:0051261 34 0.025
response to growth factor GO:0070848 198 0.025
cation transmembrane transport GO:0098655 266 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
neuronal action potential GO:0019228 54 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
peptidyl serine modification GO:0018209 83 0.025
morphogenesis of embryonic epithelium GO:0016331 159 0.024
multicellular organismal signaling GO:0035637 91 0.024
jnk cascade GO:0007254 72 0.024
Fly
mesodermal cell migration GO:0008078 4 0.024
nitrogen compound transport GO:0071705 271 0.024
myelination in peripheral nervous system GO:0022011 19 0.024
memory GO:0007613 58 0.024
regulation of membrane potential GO:0042391 192 0.024
histone modification GO:0016570 159 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
regulation of cytoskeleton organization GO:0051493 122 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
actin polymerization or depolymerization GO:0008154 54 0.024
endocytosis GO:0006897 168 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.023
muscle fiber development GO:0048747 76 0.023
regulation of cytoplasmic transport GO:1903649 112 0.023
regulation of t cell activation GO:0050863 170 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
carbohydrate metabolic process GO:0005975 230 0.023
purine nucleotide catabolic process GO:0006195 211 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
negative regulation of protein modification process GO:0031400 163 0.023
cytokinesis GO:0000910 17 0.023
positive regulation of intracellular transport GO:0032388 70 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
cellular response to biotic stimulus GO:0071216 92 0.022
centrosome organization GO:0051297 26 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
regulation of protein transport GO:0051223 163 0.022
nuclear division GO:0000280 158 0.022
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
cytoplasmic transport GO:0016482 234 0.022
regulation of transferase activity GO:0051338 263 0.022
tube formation GO:0035148 140 0.022
neural tube formation GO:0001841 108 0.021
regulation of actin polymerization or depolymerization GO:0008064 45 0.021
positive regulation of organelle organization GO:0010638 128 0.021
placenta development GO:0001890 140 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
regulation of mitotic cell cycle GO:0007346 126 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
regulation of system process GO:0044057 200 0.021
stress activated mapk cascade GO:0051403 80 0.021
Fly
spindle assembly involved in mitosis GO:0090307 4 0.021
cellular response to organonitrogen compound GO:0071417 145 0.020
Fly
cellular response to dna damage stimulus GO:0006974 207 0.020
regulation of actin filament length GO:0030832 45 0.020
gene silencing GO:0016458 38 0.020
wound healing GO:0042060 157 0.020
lipid localization GO:0010876 126 0.020
positive regulation of transferase activity GO:0051347 167 0.020
alpha beta t cell activation GO:0046631 91 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
cytokine production GO:0001816 319 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
signal transduction by p53 class mediator GO:0072331 51 0.020
single organismal cell cell adhesion GO:0016337 131 0.019
regulation of leukocyte proliferation GO:0070663 121 0.019
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.019
spindle assembly involved in female meiosis i GO:0007057 2 0.019
regulation of mapk cascade GO:0043408 248 0.019
Fly
cellular response to hormone stimulus GO:0032870 150 0.019
Fly
regulation of glucose metabolic process GO:0010906 60 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
peptidyl serine phosphorylation GO:0018105 74 0.019
divalent inorganic cation transport GO:0072511 178 0.019
regulation of cell migration GO:0030334 219 0.019
cellularization GO:0007349 1 0.018
adult behavior GO:0030534 135 0.018
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.018
heart morphogenesis GO:0003007 178 0.018
regulation of ion transport GO:0043269 215 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
regulation of hormone levels GO:0010817 211 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
nucleotide catabolic process GO:0009166 217 0.018
protein import GO:0017038 101 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
protein localization to membrane GO:0072657 108 0.018
regulation of cell shape GO:0008360 39 0.018
actomyosin structure organization GO:0031032 56 0.018
hindbrain development GO:0030902 128 0.018
positive regulation of cell activation GO:0050867 158 0.018
cellular alcohol metabolic process GO:0044107 3 0.018
leukocyte proliferation GO:0070661 172 0.018
carbohydrate homeostasis GO:0033500 128 0.018
regulation of hydrolase activity GO:0051336 246 0.018
actin filament polymerization GO:0030041 44 0.018
inflammatory response GO:0006954 244 0.018
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.017
glucose homeostasis GO:0042593 128 0.017
protein deubiquitination GO:0016579 19 0.017
glucose metabolic process GO:0006006 92 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
positive regulation of ras gtpase activity GO:0032320 65 0.017
regulation of response to wounding GO:1903034 189 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
insulin metabolic process GO:1901142 3 0.017
oocyte axis specification GO:0007309 2 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
cell growth GO:0016049 130 0.017
cell type specific apoptotic process GO:0097285 268 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
regulation of alpha beta t cell activation GO:0046634 53 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
glycosyl compound catabolic process GO:1901658 206 0.016
circulatory system process GO:0003013 197 0.016
medulla oblongata development GO:0021550 3 0.016
myeloid cell differentiation GO:0030099 233 0.016
organ growth GO:0035265 117 0.016
positive regulation of nervous system development GO:0051962 221 0.016
negative regulation of cell cycle GO:0045786 123 0.016
lipid biosynthetic process GO:0008610 179 0.016
regulation of nucleocytoplasmic transport GO:0046822 73 0.016
neuron death GO:0070997 154 0.016
ameboidal type cell migration GO:0001667 128 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
regulation of protein localization GO:0032880 231 0.016
fat cell differentiation GO:0045444 160 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
regulation of proteolysis GO:0030162 164 0.016
response to inorganic substance GO:0010035 96 0.016
axon target recognition GO:0007412 4 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
myeloid cell homeostasis GO:0002262 114 0.016
homeostasis of number of cells GO:0048872 210 0.016
b cell activation GO:0042113 161 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.016
response to muscle inactivity GO:0014870 4 0.016
regulation of actin filament based process GO:0032970 99 0.015
mitochondrion distribution GO:0048311 4 0.015
regulation of secretion GO:0051046 274 0.015
regulation of protein targeting GO:1903533 61 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
dendrite development GO:0016358 115 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
regulation of anatomical structure size GO:0090066 178 0.015
Fly
guanosine containing compound catabolic process GO:1901069 144 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
response to peptide hormone GO:0043434 127 0.015
Fly
axon ensheathment GO:0008366 76 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
regulation of protein catabolic process GO:0042176 108 0.015
positive regulation of protein catabolic process GO:0045732 60 0.015
erythrocyte differentiation GO:0030218 88 0.015
protein processing GO:0016485 163 0.015
aromatic compound catabolic process GO:0019439 286 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
stem cell proliferation GO:0072089 117 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
monosaccharide biosynthetic process GO:0046364 44 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
Fly
purine nucleoside catabolic process GO:0006152 205 0.015
regulation of b cell activation GO:0050864 81 0.015
cellular response to lipid GO:0071396 145 0.014
epithelial cell development GO:0002064 159 0.014
male gamete generation GO:0048232 285 0.014
cell junction organization GO:0034330 77 0.014
positive regulation of protein localization to nucleus GO:1900182 30 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
maintenance of protein location in nucleus GO:0051457 2 0.014
metaphase plate congression GO:0051310 2 0.014
regulation of protein complex assembly GO:0043254 83 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
skeletal muscle organ development GO:0060538 163 0.014
response to organic cyclic compound GO:0014070 198 0.014
gtp metabolic process GO:0046039 144 0.014
gastrulation GO:0007369 116 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902237 3 0.014
t cell differentiation GO:0030217 174 0.014
regulation of cytokine production GO:0001817 266 0.014
positive regulation of cell cycle process GO:0090068 61 0.014
regulation of striated muscle cell differentiation GO:0051153 81 0.014
positive regulation of response to wounding GO:1903036 66 0.014
regulation of ral gtpase activity GO:0032315 4 0.014
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.014
negative regulation of cell activation GO:0050866 111 0.014
regulation of smad protein import into nucleus GO:0060390 3 0.014
heterocycle catabolic process GO:0046700 280 0.014
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.014
multicellular organism growth GO:0035264 161 0.014
connective tissue development GO:0061448 179 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
spindle assembly involved in meiosis GO:0090306 4 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
nuclear import GO:0051170 95 0.013
microtubule nucleation GO:0007020 2 0.013
innate immune response GO:0045087 157 0.013
epithelial tube formation GO:0072175 130 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
actin filament based movement GO:0030048 23 0.013
response to transforming growth factor beta GO:0071559 88 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
regulation of kinase activity GO:0043549 249 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
embryonic placenta development GO:0001892 98 0.013
intracellular receptor signaling pathway GO:0030522 74 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
positive regulation of protein import into nucleus GO:0042307 26 0.013
regulation of intracellular transport GO:0032386 159 0.013
response to oxidative stress GO:0006979 123 0.013
regulation of cell substrate adhesion GO:0010810 73 0.013
bmp signaling pathway GO:0030509 93 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.013
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.013
mitotic cytokinesis GO:0000281 4 0.013
rho protein signal transduction GO:0007266 32 0.013
mitotic nuclear division GO:0007067 48 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
response to oxygen levels GO:0070482 62 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
myelination GO:0042552 74 0.013
developmental cell growth GO:0048588 84 0.012
mrna metabolic process GO:0016071 84 0.012
neuron projection extension GO:1990138 64 0.012
midgut development GO:0007494 4 0.012
positive regulation of cell motility GO:2000147 116 0.012
nucleoside metabolic process GO:0009116 246 0.012
regulation of circadian rhythm GO:0042752 58 0.012
response to amino acid GO:0043200 37 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.012
response to acid chemical GO:0001101 111 0.012
myosin filament assembly GO:0031034 2 0.012
cardiac muscle tissue morphogenesis GO:0055008 44 0.012
cell junction assembly GO:0034329 52 0.012
microtubule polymerization or depolymerization GO:0031109 26 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
regulation of endocytosis GO:0030100 69 0.012
developmental maturation GO:0021700 193 0.012
regulation of hippo signaling GO:0035330 1 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
glial cell differentiation GO:0010001 131 0.012
regionalization GO:0003002 337 0.012
divalent metal ion transport GO:0070838 172 0.012
regulation of binding GO:0051098 111 0.012
nuclear transport GO:0051169 139 0.012
regulation of metal ion transport GO:0010959 106 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
apical constriction GO:0003383 4 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
oxidation reduction process GO:0055114 342 0.012
renal system development GO:0072001 225 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
ovulation cycle GO:0042698 59 0.011
actin mediated cell contraction GO:0070252 15 0.011
learning or memory GO:0007611 148 0.011
negative regulation of nervous system development GO:0051961 156 0.011
positive regulation of cell development GO:0010720 237 0.011
mitotic sister chromatid segregation GO:0000070 14 0.011
positive regulation of nfat protein import into nucleus GO:0051533 1 0.011
mesoderm development GO:0007498 100 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
cellular response to oxidative stress GO:0034599 76 0.011
regulation of transmembrane transport GO:0034762 128 0.011
cell matrix adhesion GO:0007160 68 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
calcium ion homeostasis GO:0055074 127 0.011
regulation of neuron death GO:1901214 134 0.011
ensheathment of neurons GO:0007272 76 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
regulation of inflammatory response GO:0050727 147 0.011
rna processing GO:0006396 105 0.011
protein localization to nucleus GO:0034504 121 0.011
meiotic cell cycle GO:0051321 122 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
positive regulation of t cell differentiation GO:0045582 52 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
response to lipopolysaccharide GO:0032496 128 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
protein targeting GO:0006605 143 0.011
vesicle organization GO:0016050 60 0.011
defense response to bacterium GO:0042742 119 0.011
regulation of ossification GO:0030278 112 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
Fly
mesoderm morphogenesis GO:0048332 64 0.011
regulation of coenzyme metabolic process GO:0051196 4 0.011
interleukin 5 secretion GO:0072603 2 0.011
axon guidance GO:0007411 141 0.011
lipid storage GO:0019915 36 0.011
regulation of muscle tissue development GO:1901861 97 0.011
maintenance of apical basal cell polarity GO:0035090 3 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
actin filament bundle assembly GO:0051017 40 0.011
positive regulation of t cell activation GO:0050870 101 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.011
tube closure GO:0060606 91 0.011
golgi localization GO:0051645 4 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 14 0.011
negative regulation of protein transport GO:0051224 46 0.011
peptide transport GO:0015833 133 0.010
fertilization GO:0009566 127 0.010
myeloid leukocyte activation GO:0002274 83 0.010
striated muscle cell development GO:0055002 125 0.010
neuroblast proliferation GO:0007405 49 0.010
cellular protein complex disassembly GO:0043624 36 0.010
schwann cell development GO:0014044 22 0.010
skin development GO:0043588 220 0.010
muscle cell development GO:0055001 133 0.010
positive regulation of intracellular protein transport GO:0090316 42 0.010

Map4k5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
organ system cancer DOID:0050686 0 0.019
sensory system disease DOID:0050155 0 0.013
musculoskeletal system disease DOID:17 0 0.013
retinal disease DOID:5679 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011