Mus musculus

0 known processes

Hcrtr1

hypocretin (orexin) receptor 1

(Aliases: Ox1r,MGC141357)

Hcrtr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.267
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.138
cellular amine metabolic process GO:0044106 44 0.137
transmembrane transport GO:0055085 412 0.129
amine metabolic process GO:0009308 45 0.124
blood circulation GO:0008015 195 0.106
Mouse
cation transport GO:0006812 399 0.094
ion transmembrane transport GO:0034220 361 0.087
cation transmembrane transport GO:0098655 266 0.086
sensory perception GO:0007600 245 0.076
Mouse
regulation of secretion GO:0051046 274 0.075
circulatory system process GO:0003013 197 0.073
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.073
cellular chemical homeostasis GO:0055082 215 0.068
cation homeostasis GO:0055080 212 0.060
cellular divalent inorganic cation homeostasis GO:0072503 127 0.051
sensory organ morphogenesis GO:0090596 242 0.050
inflammatory response GO:0006954 244 0.048
peptidyl amino acid modification GO:0018193 336 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.048
cellular ketone metabolic process GO:0042180 84 0.048
regulation of secretion by cell GO:1903530 249 0.047
cellular amino acid metabolic process GO:0006520 103 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.045
regulation of system process GO:0044057 200 0.045
regulation of transferase activity GO:0051338 263 0.044
calcium ion transport GO:0006816 159 0.044
urogenital system development GO:0001655 261 0.044
response to organonitrogen compound GO:0010243 246 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
muscle tissue development GO:0060537 308 0.043
positive regulation of cell development GO:0010720 237 0.042
positive regulation of secretion by cell GO:1903532 114 0.042
heart contraction GO:0060047 93 0.042
positive regulation of secretion GO:0051047 130 0.041
muscle contraction GO:0006936 101 0.041
negative regulation of protein metabolic process GO:0051248 282 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
striated muscle tissue development GO:0014706 293 0.040
epithelial cell development GO:0002064 159 0.038
purine containing compound metabolic process GO:0072521 311 0.038
positive regulation of protein modification process GO:0031401 299 0.038
respiratory system development GO:0060541 190 0.037
regulation of blood pressure GO:0008217 93 0.036
Mouse
nucleotide metabolic process GO:0009117 332 0.036
organic anion transport GO:0015711 137 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
cytokine production GO:0001816 319 0.035
metal ion homeostasis GO:0055065 189 0.035
cellular metal ion homeostasis GO:0006875 151 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
cellular ion homeostasis GO:0006873 165 0.033
inorganic ion transmembrane transport GO:0098660 234 0.032
cell type specific apoptotic process GO:0097285 268 0.031
locomotory behavior GO:0007626 195 0.031
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.031
negative regulation of phosphorylation GO:0042326 166 0.031
ear development GO:0043583 200 0.031
regulation of protein localization GO:0032880 231 0.031
norepinephrine transport GO:0015874 2 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.030
cellular homeostasis GO:0019725 240 0.030
negative regulation of molecular function GO:0044092 258 0.030
oxidation reduction process GO:0055114 342 0.030
organelle localization GO:0051640 179 0.030
nitrogen compound transport GO:0071705 271 0.030
blood vessel morphogenesis GO:0048514 285 0.029
regulation of cellular component biogenesis GO:0044087 181 0.028
glycoprotein metabolic process GO:0009100 116 0.028
negative regulation of cell development GO:0010721 169 0.027
sensory perception of mechanical stimulus GO:0050954 107 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
divalent inorganic cation transport GO:0072511 178 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
leukocyte differentiation GO:0002521 342 0.027
forebrain development GO:0030900 302 0.027
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
cytoplasmic transport GO:0016482 234 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
anion transmembrane transport GO:0098656 71 0.026
epithelial tube morphogenesis GO:0060562 303 0.026
regulation of action potential GO:0098900 4 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
regulation of cell activation GO:0050865 289 0.025
membrane organization GO:0061024 245 0.025
regulation of membrane potential GO:0042391 192 0.025
regulation of neuron differentiation GO:0045664 281 0.025
protein catabolic process GO:0030163 221 0.025
regulation of ion transport GO:0043269 215 0.025
axonogenesis GO:0007409 274 0.024
Mouse
microtubule based process GO:0007017 236 0.024
kidney development GO:0001822 213 0.024
response to radiation GO:0009314 165 0.024
apoptotic signaling pathway GO:0097190 306 0.023
regulation of blood circulation GO:1903522 93 0.023
cellular calcium ion homeostasis GO:0006874 119 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
protein ubiquitination GO:0016567 171 0.023
regulation of hormone levels GO:0010817 211 0.023
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.023
macromolecule catabolic process GO:0009057 281 0.023
regulation of muscle contraction GO:0006937 49 0.022
cell adhesion GO:0007155 329 0.022
norepinephrine secretion GO:0048243 2 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
regulation of cytokine production GO:0001817 266 0.022
spermatogenesis GO:0007283 284 0.022
skeletal muscle organ development GO:0060538 163 0.022
negative regulation of protein modification process GO:0031400 163 0.022
regulation of blood vessel size GO:0050880 56 0.022
renal system development GO:0072001 225 0.021
calcium ion homeostasis GO:0055074 127 0.021
muscle cell differentiation GO:0042692 261 0.021
regulation of heart contraction GO:0008016 77 0.021
regulation of muscle tissue development GO:1901861 97 0.021
carboxylic acid transport GO:0046942 100 0.021
vascular process in circulatory system GO:0003018 62 0.021
regulation of postsynaptic membrane potential GO:0060078 48 0.021
nucleoside metabolic process GO:0009116 246 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
regulation of cell motility GO:2000145 236 0.020
maintenance of location GO:0051235 89 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
skeletal system development GO:0001501 356 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
detection of abiotic stimulus GO:0009582 60 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
regulation of kinase activity GO:0043549 249 0.020
detection of stimulus GO:0051606 84 0.020
intracellular protein transport GO:0006886 204 0.020
regulation of cell projection organization GO:0031344 206 0.020
regulation of cell migration GO:0030334 219 0.020
regulation of carbohydrate metabolic process GO:0006109 75 0.020
peptidyl serine modification GO:0018209 83 0.019
angiogenesis GO:0001525 201 0.019
muscle system process GO:0003012 141 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
regulation of organelle organization GO:0033043 289 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
Mouse Rat
heart process GO:0003015 94 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.018
anion transport GO:0006820 177 0.018
l alpha amino acid transmembrane transport GO:1902475 23 0.018
cellular response to lipid GO:0071396 145 0.018
response to insulin GO:0032868 100 0.018
regulation of anatomical structure size GO:0090066 178 0.018
placenta development GO:0001890 140 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
regulation of tube size GO:0035150 57 0.018
appendage development GO:0048736 166 0.018
aromatic compound catabolic process GO:0019439 286 0.018
endocrine process GO:0050886 39 0.018
branching morphogenesis of an epithelial tube GO:0048754 159 0.018
organic hydroxy compound transport GO:0015850 93 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
response to light stimulus GO:0009416 135 0.018
myotube differentiation GO:0014902 105 0.017
peptidyl serine phosphorylation GO:0018105 74 0.017
regulation of proteolysis GO:0030162 164 0.017
protein maturation GO:0051604 176 0.017
striated muscle cell development GO:0055002 125 0.017
sequestering of calcium ion GO:0051208 18 0.017
action potential GO:0001508 78 0.017
sodium ion transmembrane transport GO:0035725 49 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of norepinephrine secretion GO:0014061 2 0.016
heterocycle catabolic process GO:0046700 280 0.016
extracellular matrix organization GO:0030198 147 0.016
immune effector process GO:0002252 321 0.016
cytosolic calcium ion homeostasis GO:0051480 70 0.016
sensory perception of sound GO:0007605 97 0.016
ear morphogenesis GO:0042471 118 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
anatomical structure homeostasis GO:0060249 145 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
neuromuscular process GO:0050905 99 0.016
negative regulation of immune system process GO:0002683 209 0.016
positive regulation of nervous system development GO:0051962 221 0.015
response to lipopolysaccharide GO:0032496 128 0.015
response to decreased oxygen levels GO:0036293 59 0.015
multicellular organism growth GO:0035264 161 0.015
Mouse
divalent metal ion transport GO:0070838 172 0.015
neurotransmitter transport GO:0006836 76 0.015
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.015
calcium ion transmembrane transport GO:0070588 85 0.015
sequestering of metal ion GO:0051238 19 0.015
membrane depolarization GO:0051899 64 0.015
dna metabolic process GO:0006259 303 0.015
cellular lipid metabolic process GO:0044255 323 0.015
cardiac muscle contraction GO:0060048 32 0.015
regulation of peptidase activity GO:0052547 96 0.015
chloride transmembrane transport GO:1902476 24 0.015
nucleotide catabolic process GO:0009166 217 0.015
protein secretion GO:0009306 111 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
negative regulation of nervous system development GO:0051961 156 0.015
regulation of protein transport GO:0051223 163 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
organic cyclic compound catabolic process GO:1901361 295 0.014
fatty acid metabolic process GO:0006631 121 0.014
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.014
feeding behavior GO:0007631 62 0.014
Mouse
leukocyte proliferation GO:0070661 172 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
regulation of neural retina development GO:0061074 3 0.014
negative regulation of inflammatory response GO:0050728 61 0.014
regulation of cellular response to stress GO:0080135 159 0.014
regulation of feeding behavior GO:0060259 3 0.014
sulfur compound metabolic process GO:0006790 100 0.014
cardiac chamber development GO:0003205 108 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
leukocyte migration GO:0050900 124 0.014
circadian rhythm GO:0007623 114 0.014
Mouse
cell activation involved in immune response GO:0002263 126 0.014
dephosphorylation GO:0016311 129 0.014
camera type eye development GO:0043010 266 0.014
response to peptide hormone GO:0043434 127 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
cell substrate adhesion GO:0031589 130 0.013
interleukin 10 secretion GO:0072608 4 0.013
detection of external stimulus GO:0009581 61 0.013
positive regulation of peptide hormone secretion GO:0090277 31 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
striated muscle contraction GO:0006941 45 0.013
sodium ion transport GO:0006814 73 0.013
rhodopsin mediated signaling pathway GO:0016056 4 0.013
regulation of muscle system process GO:0090257 80 0.013
regulation of response to wounding GO:1903034 189 0.013
protein localization to organelle GO:0033365 185 0.013
myeloid cell differentiation GO:0030099 233 0.013
lymphocyte differentiation GO:0030098 242 0.013
inorganic anion transport GO:0015698 43 0.013
ras protein signal transduction GO:0007265 77 0.013
positive regulation of ion transport GO:0043270 65 0.013
digestive system development GO:0055123 200 0.013
Mouse
regulation of myotube differentiation GO:0010830 62 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
response to oxygen levels GO:0070482 62 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
respiratory tube development GO:0030323 167 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.013
epithelial cell proliferation GO:0050673 174 0.013
endocytosis GO:0006897 168 0.013
regulation of transmembrane transport GO:0034762 128 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
nephron development GO:0072006 109 0.012
hormone secretion GO:0046879 128 0.012
positive regulation of dopamine secretion GO:0033603 2 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
digestive tract development GO:0048565 190 0.012
Mouse
regulation of neuron death GO:1901214 134 0.012
carbohydrate metabolic process GO:0005975 230 0.012
Mouse
purine nucleoside metabolic process GO:0042278 241 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
skin development GO:0043588 220 0.012
nephron epithelium development GO:0072009 92 0.012
wnt signaling pathway GO:0016055 188 0.012
mitochondrion organization GO:0007005 134 0.012
regulation of cell cycle GO:0051726 281 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
response to hypoxia GO:0001666 58 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
protein processing GO:0016485 163 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.012
carbohydrate homeostasis GO:0033500 128 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.012
negative regulation of protein maturation GO:1903318 79 0.012
leukocyte mediated immunity GO:0002443 174 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of protein maturation GO:1903317 96 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
response to ischemia GO:0002931 14 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
positive regulation of transferase activity GO:0051347 167 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
rhythmic process GO:0048511 174 0.012
Mouse
engulfment of apoptotic cell GO:0043652 3 0.012
sperm motility GO:0030317 47 0.011
regulation of inflammatory response GO:0050727 147 0.011
proteoglycan metabolic process GO:0006029 38 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
regulation of renin secretion into blood stream GO:1900133 4 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
endocardium formation GO:0060214 4 0.011
nephron tubule development GO:0072080 84 0.011
regulation of neurotransmitter transport GO:0051588 35 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
regulation of hydrolase activity GO:0051336 246 0.011
positive regulation of cell motility GO:2000147 116 0.011
regulation of protein kinase activity GO:0045859 232 0.011
t cell activation GO:0042110 289 0.011
regulation of ion homeostasis GO:2000021 64 0.011
mucopolysaccharide metabolic process GO:1903510 25 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
mapk cascade GO:0000165 281 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
cyclic nucleotide metabolic process GO:0009187 59 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.011
compound eye development GO:0048749 1 0.011
cardiac muscle tissue development GO:0048738 130 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
cardiocyte differentiation GO:0035051 87 0.011
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of homeostatic process GO:0032844 182 0.011
fat cell differentiation GO:0045444 160 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
amide transport GO:0042886 138 0.011
telencephalon development GO:0021537 186 0.011
vasodilation GO:0042311 28 0.011
organophosphate catabolic process GO:0046434 232 0.011
purine nucleotide biosynthetic process GO:0006164 65 0.011
respiratory gaseous exchange GO:0007585 43 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
cellular response to hormone stimulus GO:0032870 150 0.010
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.010
proton transport GO:0015992 35 0.010
endomembrane system organization GO:0010256 147 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
positive regulation of cytokine production GO:0001819 174 0.010
appendage morphogenesis GO:0035107 149 0.010
regulation of calcium ion transport GO:0051924 69 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
negative regulation of protein processing GO:0010955 79 0.010
myotube cell development GO:0014904 60 0.010
extracellular structure organization GO:0043062 148 0.010
renal system process GO:0003014 48 0.010
regulation of body fluid levels GO:0050878 162 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
retina development in camera type eye GO:0060041 119 0.010
inner ear morphogenesis GO:0042472 101 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010

Hcrtr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.026
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019