Mus musculus

18 known processes

Fbl

fibrillarin

(Aliases: FIB,AL022665,RNU3IP1,FLRN)

Fbl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 105 0.525
cellular nitrogen compound catabolic process GO:0044270 280 0.501
maturation of ssu rrna GO:0030490 1 0.398
nucleoside metabolic process GO:0009116 246 0.396
rna splicing via transesterification reactions GO:0000375 43 0.380
aromatic compound catabolic process GO:0019439 286 0.363
organic cyclic compound catabolic process GO:1901361 295 0.333
negative regulation of dna templated transcription termination GO:0060567 1 0.310
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.297
regulation of nucleotide metabolic process GO:0006140 169 0.254
mrna metabolic process GO:0016071 84 0.250
intracellular mrna localization GO:0008298 4 0.230
microtubule based process GO:0007017 236 0.228
epithelial tube morphogenesis GO:0060562 303 0.217
ribonucleoside metabolic process GO:0009119 245 0.210
oocyte anterior posterior axis specification GO:0007314 2 0.199
regulation of nucleoside metabolic process GO:0009118 130 0.192
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.189
ribose phosphate metabolic process GO:0019693 291 0.185
nucleoside triphosphate metabolic process GO:0009141 230 0.179
purine containing compound metabolic process GO:0072521 311 0.156
ion transmembrane transport GO:0034220 361 0.144
microtubule cytoskeleton organization GO:0000226 157 0.143
regulation of purine nucleotide catabolic process GO:0033121 122 0.140
negative regulation of atpase activity GO:0032780 2 0.136
oocyte construction GO:0007308 2 0.129
cellular homeostasis GO:0019725 240 0.126
rrna processing GO:0006364 10 0.125
ribonucleotide metabolic process GO:0009259 291 0.123
glycosyl compound catabolic process GO:1901658 206 0.122
purine nucleotide catabolic process GO:0006195 211 0.118
nucleoside triphosphate catabolic process GO:0009143 205 0.116
nucleobase containing small molecule metabolic process GO:0055086 352 0.110
ribonucleoside catabolic process GO:0042454 206 0.106
purine ribonucleoside catabolic process GO:0046130 205 0.106
nucleotide catabolic process GO:0009166 217 0.102
nucleotide metabolic process GO:0009117 332 0.098
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.094
purine nucleoside catabolic process GO:0006152 205 0.092
organonitrogen compound catabolic process GO:1901565 264 0.091
transcription coupled nucleotide excision repair GO:0006283 2 0.089
organophosphate catabolic process GO:0046434 232 0.086
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.085
rna splicing GO:0008380 54 0.083
regionalization GO:0003002 337 0.082
transcription from rna polymerase i promoter GO:0006360 13 0.082
heterocycle catabolic process GO:0046700 280 0.080
mitotic cell cycle process GO:1903047 159 0.079
negative regulation of nucleotide catabolic process GO:0030812 9 0.079
rna catabolic process GO:0006401 29 0.077
carbohydrate derivative catabolic process GO:1901136 231 0.074
purine nucleotide metabolic process GO:0006163 302 0.069
purine ribonucleotide catabolic process GO:0009154 208 0.066
ribonucleoside triphosphate catabolic process GO:0009203 199 0.066
glycosyl compound metabolic process GO:1901657 246 0.065
purine containing compound catabolic process GO:0072523 213 0.063
dna dealkylation GO:0035510 11 0.061
purine nucleotide biosynthetic process GO:0006164 65 0.060
purine nucleoside triphosphate catabolic process GO:0009146 203 0.058
poly a mrna export from nucleus GO:0016973 4 0.055
mrna splicing via spliceosome GO:0000398 43 0.054
regulation of mrna splicing via spliceosome GO:0048024 32 0.054
ribosome biogenesis GO:0042254 20 0.052
rrna metabolic process GO:0016072 10 0.052
purine nucleoside triphosphate metabolic process GO:0009144 226 0.052
myeloid cell differentiation GO:0030099 233 0.052
macromolecule methylation GO:0043414 120 0.051
Human
purine nucleoside metabolic process GO:0042278 241 0.051
nucleoside phosphate catabolic process GO:1901292 222 0.050
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.049
nucleoside phosphate metabolic process GO:0006753 338 0.049
negative regulation of nucleotide metabolic process GO:0045980 16 0.049
ribonucleotide catabolic process GO:0009261 208 0.049
posttranscriptional regulation of gene expression GO:0010608 155 0.048
Worm
ribose phosphate biosynthetic process GO:0046390 59 0.048
endocytosis GO:0006897 168 0.047
cellular response to dna damage stimulus GO:0006974 207 0.047
regulation of nucleotide catabolic process GO:0030811 122 0.047
leukocyte proliferation GO:0070661 172 0.044
regulation of atp metabolic process GO:1903578 17 0.044
ossification GO:0001503 216 0.043
Human
negative regulation of cellular component organization GO:0051129 194 0.043
atp metabolic process GO:0046034 75 0.042
negative regulation of molecular function GO:0044092 258 0.042
oxidation reduction process GO:0055114 342 0.041
mrna processing GO:0006397 63 0.041
regulation of rna splicing GO:0043484 37 0.041
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.040
regulation of mrna processing GO:0050684 41 0.040
ribosomal small subunit biogenesis GO:0042274 4 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
positive regulation of mrna metabolic process GO:1903313 17 0.040
organelle assembly GO:0070925 177 0.039
purine ribonucleoside metabolic process GO:0046128 241 0.038
pole plasm assembly GO:0007315 2 0.038
purine ribonucleotide metabolic process GO:0009150 290 0.038
cell cell recognition GO:0009988 44 0.037
development of primary sexual characteristics GO:0045137 143 0.037
Worm
embryonic organ morphogenesis GO:0048562 276 0.037
hematopoietic progenitor cell differentiation GO:0002244 143 0.036
ncrna processing GO:0034470 26 0.036
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.036
respiratory system development GO:0060541 190 0.036
dna repair GO:0006281 107 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.033
cellular response to cytokine stimulus GO:0071345 189 0.033
regulation of purine nucleotide metabolic process GO:1900542 169 0.033
peptidyl arginine omega n methylation GO:0035247 2 0.033
nucleoside catabolic process GO:0009164 206 0.033
cell adhesion GO:0007155 329 0.032
regulation of cell adhesion GO:0030155 154 0.031
ribonucleoside monophosphate catabolic process GO:0009158 57 0.030
purine containing compound biosynthetic process GO:0072522 70 0.030
leukocyte differentiation GO:0002521 342 0.030
genitalia development GO:0048806 37 0.030
cleavage involved in rrna processing GO:0000469 1 0.029
regulation of cell motility GO:2000145 236 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.029
positive regulation of dna templated transcription elongation GO:0032786 2 0.029
atp catabolic process GO:0006200 55 0.029
amine metabolic process GO:0009308 45 0.028
regulation of mrna metabolic process GO:1903311 43 0.028
transmembrane transport GO:0055085 412 0.027
axon guidance GO:0007411 141 0.027
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
negative regulation of protein binding GO:0032091 17 0.026
maturation of lsu rrna GO:0000470 1 0.026
purine nucleoside monophosphate metabolic process GO:0009126 81 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
regulation of organelle organization GO:0033043 289 0.025
regulation of mitotic cell cycle GO:0007346 126 0.025
organelle fission GO:0048285 170 0.025
nucleic acid transport GO:0050657 18 0.024
regulation of hydrolase activity GO:0051336 246 0.024
alternative mrna splicing via spliceosome GO:0000380 12 0.023
anion transport GO:0006820 177 0.023
maternal determination of anterior posterior axis embryo GO:0008358 2 0.023
sensory organ morphogenesis GO:0090596 242 0.023
positive regulation of cell cycle phase transition GO:1901989 17 0.023
cation homeostasis GO:0055080 212 0.022
stem cell differentiation GO:0048863 268 0.022
regulation of dna templated transcription termination GO:0031554 1 0.022
regulation of double strand break repair via homologous recombination GO:0010569 2 0.022
cell division GO:0051301 120 0.022
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.022
fertilization GO:0009566 127 0.022
embryonic heart tube morphogenesis GO:0003143 51 0.022
molting cycle GO:0042303 90 0.021
mitotic cell cycle GO:0000278 195 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
cytoplasmic transport GO:0016482 234 0.021
regulation of gtp catabolic process GO:0033124 113 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
regulation of cell cycle GO:0051726 281 0.020
gtp catabolic process GO:0006184 143 0.020
negative regulation of nucleoside metabolic process GO:0045978 11 0.020
retina development in camera type eye GO:0060041 119 0.020
purine nucleoside monophosphate catabolic process GO:0009128 58 0.020
regulation of translation GO:0006417 71 0.019
Worm
segmentation GO:0035282 93 0.019
lymphocyte proliferation GO:0046651 164 0.019
chemotaxis GO:0006935 247 0.019
mitochondrial fusion GO:0008053 9 0.019
pharynx development GO:0060465 1 0.019
guanosine containing compound metabolic process GO:1901068 144 0.018
demethylation GO:0070988 23 0.018
striated muscle myosin thick filament assembly GO:0071688 1 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
regulation of cell migration GO:0030334 219 0.018
regulation of protein binding GO:0043393 60 0.018
embryonic heart tube development GO:0035050 65 0.018
gonad development GO:0008406 141 0.017
Worm
transcription from rna polymerase iii promoter GO:0006383 3 0.017
rna localization GO:0006403 23 0.017
epithelial cell proliferation GO:0050673 174 0.017
dephosphorylation GO:0016311 129 0.017
cation transport GO:0006812 399 0.017
single fertilization GO:0007338 82 0.017
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.017
establishment of rna localization GO:0051236 18 0.016
receptor mediated endocytosis GO:0006898 51 0.016
cell maturation GO:0048469 127 0.016
regulation of protein localization GO:0032880 231 0.016
determination of heart left right asymmetry GO:0061371 48 0.016
regulation of organ morphogenesis GO:2000027 144 0.016
nitrogen compound transport GO:0071705 271 0.016
methylation GO:0032259 134 0.015
Human
multicellular organism growth GO:0035264 161 0.015
camera type eye development GO:0043010 266 0.015
response to acid chemical GO:0001101 111 0.015
pore complex assembly GO:0046931 3 0.015
negative regulation of cell development GO:0010721 169 0.015
glycoprotein metabolic process GO:0009100 116 0.015
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.015
sodium ion transport GO:0006814 73 0.015
nuclear transcribed mrna catabolic process GO:0000956 16 0.015
nuclear division GO:0000280 158 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
cellular chemical homeostasis GO:0055082 215 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.014
regulation of mitotic cell cycle phase transition GO:1901990 73 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
positive regulation of cell cycle process GO:0090068 61 0.014
sensory perception GO:0007600 245 0.014
negative regulation of immune system process GO:0002683 209 0.014
oocyte axis specification GO:0007309 2 0.014
translation GO:0006412 93 0.014
Worm
cytoplasmic translational initiation GO:0002183 3 0.014
positive regulation of dna repair GO:0045739 3 0.014
spindle organization GO:0007051 28 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
viral process GO:0016032 41 0.013
germ cell development GO:0007281 185 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
digestive tract development GO:0048565 190 0.013
determination of left right symmetry GO:0007368 80 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
monosaccharide metabolic process GO:0005996 106 0.013
angiogenesis GO:0001525 201 0.013
macromolecule catabolic process GO:0009057 281 0.013
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.012
gtp metabolic process GO:0046039 144 0.012
nuclear export GO:0051168 34 0.012
cellular amino acid metabolic process GO:0006520 103 0.012
intracellular protein transport GO:0006886 204 0.012
single organism cell adhesion GO:0098602 156 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
ribonucleoprotein complex subunit organization GO:0071826 28 0.012
maturation of 5 8s rrna GO:0000460 1 0.012
toxin transport GO:1901998 38 0.012
regulation of cell substrate adhesion GO:0010810 73 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
glucose homeostasis GO:0042593 128 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
mesenchymal cell differentiation GO:0048762 107 0.012
cell chemotaxis GO:0060326 81 0.012
blood vessel morphogenesis GO:0048514 285 0.012
regulation of cell division GO:0051302 76 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
gland development GO:0048732 330 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
dna demethylation GO:0080111 10 0.011
regulation of cell maturation GO:1903429 13 0.011
skeletal system morphogenesis GO:0048705 203 0.011
cell substrate adhesion GO:0031589 130 0.011
regulation of cellular response to stress GO:0080135 159 0.011
oocyte development GO:0048599 33 0.011
mitotic g1 dna damage checkpoint GO:0031571 4 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
cellular amine metabolic process GO:0044106 44 0.011
metal ion homeostasis GO:0055065 189 0.011
interspecies interaction between organisms GO:0044419 83 0.011
nucleobase containing compound transport GO:0015931 27 0.011
developmental maturation GO:0021700 193 0.010
regulation of homeostatic process GO:0032844 182 0.010
cellular protein complex assembly GO:0043623 116 0.010
cellular response to lipid GO:0071396 145 0.010
morphogenesis of a branching structure GO:0001763 203 0.010

Fbl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
large intestine cancer DOID:5672 0 0.026
colon cancer DOID:219 0 0.026
gastrointestinal system cancer DOID:3119 0 0.026
intestinal cancer DOID:10155 0 0.026
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
colorectal cancer DOID:9256 0 0.026
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.021
central nervous system disease DOID:331 0 0.020
immune system cancer DOID:0060083 0 0.019
retinal disease DOID:5679 0 0.012
retinal degeneration DOID:8466 0 0.011