|
|
natural killer cell inhibitory signaling pathway
|
GO:0002769 |
2 |
1.000
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.999
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.998
|
Mouse |
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.997
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.993
|
Mouse |
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.985
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.982
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.978
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.974
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.973
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.972
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.971
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.971
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.967
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.967
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.960
|
|
|
|
negative regulation of natural killer cell mediated immunity
|
GO:0002716 |
5 |
0.952
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.951
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.948
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.947
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.943
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.941
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.940
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.936
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.933
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.916
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.910
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.907
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.906
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.901
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.900
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.896
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.894
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.872
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.867
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.866
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.863
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.858
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.854
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.844
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.824
|
Mouse |
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.815
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.812
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.807
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.770
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.769
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.765
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.757
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.738
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.731
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.725
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.721
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.717
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.711
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.708
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.705
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.697
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.695
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.678
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.669
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.658
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.651
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.634
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.616
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.604
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.577
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.575
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.571
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.550
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.545
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.511
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.470
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.460
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.398
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.394
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.392
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.343
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.341
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.334
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.325
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.320
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.313
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.254
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.251
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.248
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.246
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.240
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.233
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.224
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.223
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.216
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.206
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.204
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.198
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.190
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.179
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.168
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.168
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.156
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.154
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.153
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.149
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.148
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.140
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.138
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.136
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.136
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.134
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.133
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.129
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.127
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.124
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.123
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.123
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.123
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.123
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.122
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.115
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.115
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.114
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.112
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.110
|
|
|
|
transepithelial chloride transport
|
GO:0030321 |
4 |
0.110
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.110
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.110
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.108
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.107
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.107
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.105
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.104
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.104
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.102
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.099
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.096
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.096
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.093
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.093
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.092
|
Mouse |
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.091
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.090
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.090
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.089
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.088
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.088
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.087
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.087
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.086
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.086
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.086
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.086
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.085
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.084
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.084
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.082
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
6 |
0.081
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.081
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.081
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.081
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.080
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.079
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.079
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.078
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.078
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.076
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.075
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.073
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.073
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.071
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.071
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.070
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.070
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.070
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.069
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.068
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.068
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.067
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.067
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.067
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.067
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.067
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.067
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.066
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.065
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.065
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.064
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.064
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.064
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.063
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.063
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.062
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.062
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.061
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.058
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.058
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.058
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.058
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.057
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.057
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.056
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.056
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.056
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.055
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.055
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.055
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.054
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.054
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.054
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.053
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.053
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.052
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.052
|
|
|
|
negative regulation of osteoclast differentiation
|
GO:0045671 |
12 |
0.052
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.051
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.050
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.050
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.050
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.050
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.049
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.049
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.048
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.048
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.048
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.047
|
|
|
|
interleukin 18 production
|
GO:0032621 |
4 |
0.046
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.046
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.046
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.046
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.046
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.046
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.045
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.045
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.045
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.045
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.045
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.045
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.045
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.044
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.044
|
|
|
|
positive regulation of oligodendrocyte differentiation
|
GO:0048714 |
9 |
0.044
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.044
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.043
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.043
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.043
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
4 |
0.043
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.042
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
7 |
0.042
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.042
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.041
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.041
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.041
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.041
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.040
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.040
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.040
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.040
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.038
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.038
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.038
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.038
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.038
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.037
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.037
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.036
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.036
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.035
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.035
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.034
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.034
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.034
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.034
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.033
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.033
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.033
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.033
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.033
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.032
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.032
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.032
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.032
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.032
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.032
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.032
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.031
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.031
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.031
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.031
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.030
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.030
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.030
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.030
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.030
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.030
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.029
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.029
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.029
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.029
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.029
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.029
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.029
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.029
|
|
|
|
smooth muscle cell chemotaxis
|
GO:0071670 |
2 |
0.029
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.029
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.028
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.028
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.028
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.028
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.028
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.028
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.028
|
|
|
|
positive regulation of glycoprotein metabolic process
|
GO:1903020 |
6 |
0.028
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.028
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.027
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.027
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.027
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.027
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.027
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.027
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.026
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.026
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.026
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.026
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.026
|
|
|
|
innate immune response in mucosa
|
GO:0002227 |
3 |
0.025
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.025
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.025
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.025
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.025
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.024
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.024
|
|
|
|
regulation of histone h3 k27 methylation
|
GO:0061085 |
6 |
0.024
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.024
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.024
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.024
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.024
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.024
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.024
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.024
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.024
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.024
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.023
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.023
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.023
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.023
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.023
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.023
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.023
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.023
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.023
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.023
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.022
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.022
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.022
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.022
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.022
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.022
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.022
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.022
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.022
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.022
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.022
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.022
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.022
|
|
|
|
regulation of bone remodeling
|
GO:0046850 |
28 |
0.022
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.022
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.022
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.022
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.021
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.021
|
|
|
|
cellular defense response
|
GO:0006968 |
6 |
0.021
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.021
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.021
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.021
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.021
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
20 |
0.021
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.021
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.021
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.021
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.021
|
|
|
|
positive regulation of interferon gamma biosynthetic process
|
GO:0045078 |
4 |
0.021
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.021
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.021
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.021
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.021
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.020
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.020
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.020
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.020
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.020
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.020
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.020
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.020
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.020
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.020
|
|
|
|
positive regulation of interferon alpha biosynthetic process
|
GO:0045356 |
1 |
0.020
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.020
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.020
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.020
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.020
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.020
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.020
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.020
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.020
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.020
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.019
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.019
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.019
|
|
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.019
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.019
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.019
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.019
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.019
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.019
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.019
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.019
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.019
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.019
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.019
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.019
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.019
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.018
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.018
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.018
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.018
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.018
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.018
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.018
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.018
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.018
|
|
|
|
positive regulation of acute inflammatory response to antigenic stimulus
|
GO:0002866 |
7 |
0.018
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.018
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
16 |
0.018
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.018
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.018
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.018
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.018
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.018
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.018
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.018
|
|
|
|
positive regulation of tissue remodeling
|
GO:0034105 |
19 |
0.018
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.017
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.017
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.017
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.017
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.017
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.017
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.017
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.017
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.017
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.017
|
|
|
|
negative regulation of interferon gamma biosynthetic process
|
GO:0045077 |
2 |
0.017
|
|
|
|
positive regulation of glycoprotein biosynthetic process
|
GO:0010560 |
6 |
0.017
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.017
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.017
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.017
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.017
|
|
|
|
negative regulation of antigen receptor mediated signaling pathway
|
GO:0050858 |
16 |
0.017
|
|
|
|
ruffle organization
|
GO:0031529 |
16 |
0.017
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.016
|
|
|
|
regulation of acute inflammatory response to non antigenic stimulus
|
GO:0002877 |
2 |
0.016
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.016
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.016
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.016
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.016
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.016
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.016
|
|
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
17 |
0.016
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.016
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.016
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.016
|
|
|
|
positive regulation of keratinocyte proliferation
|
GO:0010838 |
4 |
0.016
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.016
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.016
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.016
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.016
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.016
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.016
|
|
|
|
negative regulation of cell killing
|
GO:0031342 |
8 |
0.016
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.016
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.016
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.016
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.016
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.016
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.016
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.016
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.016
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.016
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.015
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.015
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.015
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.015
|
|
