Mus musculus

91 known processes

Fbxo5

F-box protein 5

(Aliases: Emi1,C85305,2510044I10Rik,Fbxo31)

Fbxo5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.498
dna metabolic process GO:0006259 303 0.195
dna repair GO:0006281 107 0.179
regulation of cell cycle GO:0051726 281 0.175
organelle fission GO:0048285 170 0.174
protein maturation GO:0051604 176 0.166
Human Fly
nuclear division GO:0000280 158 0.118
negative regulation of cellular protein metabolic process GO:0032269 247 0.116
Human Fly
negative regulation of cellular catabolic process GO:0031330 47 0.112
Human Fly
protein ubiquitination GO:0016567 171 0.102
Human Fly
male gamete generation GO:0048232 285 0.100
cellular macromolecule catabolic process GO:0044265 206 0.099
Human Fly
chromatin modification GO:0016568 187 0.089
meiotic nuclear division GO:0007126 115 0.084
regulation of chromosome organization GO:0033044 83 0.083
Human Fly
macromolecule catabolic process GO:0009057 281 0.081
Human Fly
germ cell development GO:0007281 185 0.075
regulation of mitotic cell cycle phase transition GO:1901990 73 0.071
Human Fly
negative regulation of protein metabolic process GO:0051248 282 0.071
Human Fly
regulation of cell cycle process GO:0010564 160 0.071
negative regulation of cell cycle GO:0045786 123 0.068
regulation of cell cycle phase transition GO:1901987 77 0.066
Human Fly
regulation of protein maturation GO:1903317 96 0.066
Human Fly
regulation of cellular amine metabolic process GO:0033238 20 0.063
negative regulation of cell division GO:0051782 24 0.063
cell division GO:0051301 120 0.062
dna recombination GO:0006310 92 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
negative regulation of organelle organization GO:0010639 90 0.059
meiotic cell cycle GO:0051321 122 0.058
protein modification by small protein conjugation GO:0032446 187 0.056
Human Fly
regulation of mitotic cell cycle GO:0007346 126 0.055
regulation of proteolysis GO:0030162 164 0.055
Human Fly
double strand break repair GO:0006302 48 0.054
amine metabolic process GO:0009308 45 0.053
negative regulation of protein processing GO:0010955 79 0.052
Human Fly
negative regulation of mitotic cell cycle GO:0045930 58 0.051
Human Zebrafish Fly
mitotic cell cycle GO:0000278 195 0.049
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.049
Human Fly
protein processing GO:0016485 163 0.049
Human Fly
peptidyl amino acid modification GO:0018193 336 0.048
negative regulation of nuclear division GO:0051784 19 0.048
cellular amine metabolic process GO:0044106 44 0.046
microtubule cytoskeleton organization GO:0000226 157 0.045
cell type specific apoptotic process GO:0097285 268 0.045
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.045
Human Fly
cellular ketone metabolic process GO:0042180 84 0.044
translesion synthesis GO:0019985 1 0.044
spermatogenesis GO:0007283 284 0.043
microtubule based process GO:0007017 236 0.043
negative regulation of cell cycle phase transition GO:1901988 48 0.043
Human Fly
positive regulation of protein modification process GO:0031401 299 0.043
protein catabolic process GO:0030163 221 0.042
Human Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.042
b cell activation GO:0042113 161 0.042
blastocyst growth GO:0001832 23 0.041
positive regulation of mitotic cell cycle GO:0045931 41 0.041
stem cell maintenance GO:0019827 130 0.040
negative regulation of cellular component organization GO:0051129 194 0.040
negative regulation of proteolysis GO:0045861 74 0.040
Human Fly
chromatin organization GO:0006325 206 0.040
negative regulation of protein maturation GO:1903318 79 0.039
Human Fly
mitotic sister chromatid cohesion GO:0007064 1 0.039
cellular protein catabolic process GO:0044257 155 0.039
Human Fly
intrinsic apoptotic signaling pathway GO:0097193 132 0.039
negative regulation of chromosome organization GO:2001251 30 0.038
Human Fly
ubiquitin dependent protein catabolic process GO:0006511 129 0.038
Human Fly
asymmetric stem cell division GO:0098722 3 0.036
histone modification GO:0016570 159 0.036
mitotic nuclear division GO:0007067 48 0.035
Human Zebrafish Fly
regulation of cell division GO:0051302 76 0.034
regulation of cell activation GO:0050865 289 0.034
regulation of nuclear division GO:0051783 56 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
regulation of lymphocyte activation GO:0051249 240 0.033
apoptotic signaling pathway GO:0097190 306 0.033
cellular amino acid metabolic process GO:0006520 103 0.033
gene silencing GO:0016458 38 0.033
lateral inhibition GO:0046331 1 0.032
Fly
stem cell development GO:0048864 219 0.032
regulation of transferase activity GO:0051338 263 0.032
Human Fly
protein modification by small protein conjugation or removal GO:0070647 207 0.030
Human Fly
meiotic cell cycle process GO:1903046 77 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
g1 s transition of mitotic cell cycle GO:0000082 57 0.030
Fly
positive regulation of nuclear division GO:0051785 27 0.029
stem cell differentiation GO:0048863 268 0.029
protein localization to organelle GO:0033365 185 0.029
covalent chromatin modification GO:0016569 163 0.029
response to light stimulus GO:0009416 135 0.029
heterocycle catabolic process GO:0046700 280 0.028
regulation of cellular response to stress GO:0080135 159 0.028
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.028
Human Fly
leukocyte mediated immunity GO:0002443 174 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
regulation of exit from mitosis GO:0007096 1 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
negative regulation of gene expression epigenetic GO:0045814 15 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.026
Human Fly
modification dependent protein catabolic process GO:0019941 133 0.026
Human Fly
regulation of organelle organization GO:0033043 289 0.025
regulation of neuron differentiation GO:0045664 281 0.025
cell cycle checkpoint GO:0000075 47 0.024
negative regulation of cell cycle process GO:0010948 69 0.023
cellular response to gamma radiation GO:0071480 4 0.023
regulation of protein processing GO:0070613 96 0.022
Human Fly
nucleoside phosphate metabolic process GO:0006753 338 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
Human Fly
nucleotide metabolic process GO:0009117 332 0.022
regulation of cellular protein catabolic process GO:1903362 61 0.022
Human Fly
regulation of protein catabolic process GO:0042176 108 0.021
Human Fly
protein import GO:0017038 101 0.021
development of primary sexual characteristics GO:0045137 143 0.021
gonad development GO:0008406 141 0.021
mitotic cell cycle process GO:1903047 159 0.021
Human Zebrafish Fly
regulation of chromatin modification GO:1903308 57 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
positive regulation of organelle organization GO:0010638 128 0.020
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.020
developmental maturation GO:0021700 193 0.020
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.020
Human Fly
regulation of cell projection organization GO:0031344 206 0.019
cell activation involved in immune response GO:0002263 126 0.019
organophosphate catabolic process GO:0046434 232 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
positive regulation of chromosome organization GO:2001252 33 0.019
regulation of microtubule cytoskeleton organization GO:0070507 37 0.019
blastocyst development GO:0001824 80 0.019
positive regulation of nervous system development GO:0051962 221 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
dendrite development GO:0016358 115 0.019
aromatic compound catabolic process GO:0019439 286 0.019
production of molecular mediator of immune response GO:0002440 103 0.019
cell fate commitment GO:0045165 210 0.019
Fly
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
synapse organization GO:0050808 125 0.018
positive regulation of cell cycle GO:0045787 92 0.018
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.018
Human Fly
positive regulation of cell death GO:0010942 224 0.018
regulation of meiotic cell cycle GO:0051445 34 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.018
Human Fly
protein polyubiquitination GO:0000209 33 0.017
positive regulation of chromosome segregation GO:0051984 4 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.017
Human Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
response to organic cyclic compound GO:0014070 198 0.017
negative regulation of mitotic sister chromatid separation GO:2000816 7 0.017
Human Fly
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.017
nucleoside catabolic process GO:0009164 206 0.017
purine containing compound metabolic process GO:0072521 311 0.017
regulation of microtubule based process GO:0032886 52 0.016
carbohydrate homeostasis GO:0033500 128 0.016
regulation of homeostatic process GO:0032844 182 0.016
response to oxidative stress GO:0006979 123 0.016
nitrogen compound transport GO:0071705 271 0.016
response to radiation GO:0009314 165 0.016
negative regulation of protein catabolic process GO:0042177 36 0.016
Human Fly
regulation of secretion GO:0051046 274 0.016
blood vessel morphogenesis GO:0048514 285 0.016
positive regulation of cell cycle process GO:0090068 61 0.016
regulation of secretion by cell GO:1903530 249 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
endocytosis GO:0006897 168 0.016
cellular response to lipid GO:0071396 145 0.016
circulatory system process GO:0003013 197 0.016
protein methylation GO:0006479 81 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
heterochromatin organization GO:0070828 4 0.015
methylation GO:0032259 134 0.015
mitotic spindle checkpoint GO:0071174 9 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.015
angiogenesis GO:0001525 201 0.015
glucose homeostasis GO:0042593 128 0.015
negative regulation of cell development GO:0010721 169 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
positive regulation of mitosis GO:0045840 14 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
lymphocyte differentiation GO:0030098 242 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
cell cycle g2 m phase transition GO:0044839 20 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
spermatid differentiation GO:0048515 115 0.014
macromolecule methylation GO:0043414 120 0.014
positive regulation of proteolysis GO:0045862 85 0.014
inner cell mass cell proliferation GO:0001833 15 0.014
mitotic spindle assembly checkpoint GO:0007094 7 0.014
negative regulation of molecular function GO:0044092 258 0.014
Human Fly
mitotic cell cycle checkpoint GO:0007093 31 0.014
somatic diversification of immune receptors GO:0002200 53 0.014
regulation of neuron projection development GO:0010975 169 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
regulation of response to dna damage stimulus GO:2001020 34 0.014
response to acid chemical GO:0001101 111 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 9 0.013
Human Fly
chromosome separation GO:0051304 14 0.013
Human Fly
protein localization to nucleus GO:0034504 121 0.013
attachment of spindle microtubules to kinetochore GO:0008608 4 0.013
positive regulation of protein ubiquitination GO:0031398 27 0.013
nucleotide catabolic process GO:0009166 217 0.013
nucleoside metabolic process GO:0009116 246 0.013
response to extracellular stimulus GO:0009991 127 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.013
spermatid development GO:0007286 108 0.013
regulation of protein ubiquitination GO:0031396 52 0.013
Human Fly
connective tissue development GO:0061448 179 0.013
synaptic transmission GO:0007268 329 0.013
regulation of cell motility GO:2000145 236 0.013
regulation of protein kinase activity GO:0045859 232 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
oxidation reduction process GO:0055114 342 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
regulation of defense response GO:0031347 233 0.013
regulation of chromatin silencing GO:0031935 2 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
cartilage development GO:0051216 140 0.013
innate immune response GO:0045087 157 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
asymmetric neuroblast division GO:0055059 1 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.012
Human Fly
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
cation transport GO:0006812 399 0.012
protein targeting GO:0006605 143 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
Human Fly
respiratory system development GO:0060541 190 0.012
cell maturation GO:0048469 127 0.012
protein alkylation GO:0008213 81 0.012
regulation of b cell activation GO:0050864 81 0.012
purine containing compound catabolic process GO:0072523 213 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
Human Fly
organonitrogen compound catabolic process GO:1901565 264 0.011
regulation of hormone levels GO:0010817 211 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
stem cell proliferation GO:0072089 117 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
cellular homeostasis GO:0019725 240 0.011
microtubule organizing center organization GO:0031023 28 0.011
carbohydrate metabolic process GO:0005975 230 0.011
immunoglobulin production GO:0002377 73 0.011
muscle tissue development GO:0060537 308 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
Human Fly
lipid biosynthetic process GO:0008610 179 0.011
rhythmic process GO:0048511 174 0.011
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 2 0.011
response to organonitrogen compound GO:0010243 246 0.011
telencephalon development GO:0021537 186 0.011
meiosis ii GO:0007135 7 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
neuron death GO:0070997 154 0.011
respiratory tube development GO:0030323 167 0.011
intracellular protein transport GO:0006886 204 0.011
oogenesis GO:0048477 56 0.011
neural tube development GO:0021915 160 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
dna endoreduplication GO:0042023 4 0.011
cell adhesion GO:0007155 329 0.010
response to uv GO:0009411 44 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
negative regulation of chromosome segregation GO:0051985 9 0.010
Human Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
hormone secretion GO:0046879 128 0.010
negative regulation of gene silencing GO:0060969 2 0.010
immune effector process GO:0002252 321 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
male gonad development GO:0008584 88 0.010
response to nutrient levels GO:0031667 109 0.010
muscle system process GO:0003012 141 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
histone methylation GO:0016571 71 0.010
regulation of embryonic development GO:0045995 71 0.010
regulation of membrane potential GO:0042391 192 0.010
compound eye development GO:0048749 1 0.010
myeloid cell differentiation GO:0030099 233 0.010

Fbxo5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.044
disease of cellular proliferation DOID:14566 0 0.044
organ system cancer DOID:0050686 0 0.042
breast cancer DOID:1612 0 0.020
thoracic cancer DOID:5093 0 0.020
large intestine cancer DOID:5672 0 0.018
gastrointestinal system cancer DOID:3119 0 0.018
intestinal cancer DOID:10155 0 0.018
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.014