Mus musculus

0 known processes

Hapln4

hyaluronan and proteoglycan link protein 4

(Aliases: Lpr4,Bral2,9330174O11)

Hapln4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amine metabolic process GO:0033238 20 0.101
synaptic transmission GO:0007268 329 0.093
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.076
regulation of membrane potential GO:0042391 192 0.075
cation transmembrane transport GO:0098655 266 0.069
inorganic cation transmembrane transport GO:0098662 207 0.059
regulation of cellular ketone metabolic process GO:0010565 66 0.058
transmembrane transport GO:0055085 412 0.055
cation transport GO:0006812 399 0.054
cellular amino acid metabolic process GO:0006520 103 0.054
cellular amine metabolic process GO:0044106 44 0.052
oxidation reduction process GO:0055114 342 0.048
organic anion transport GO:0015711 137 0.047
transmission of nerve impulse GO:0019226 76 0.046
blood circulation GO:0008015 195 0.045
cellular ketone metabolic process GO:0042180 84 0.045
striated muscle tissue development GO:0014706 293 0.045
amine metabolic process GO:0009308 45 0.044
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
mapk cascade GO:0000165 281 0.041
ion transmembrane transport GO:0034220 361 0.040
immune effector process GO:0002252 321 0.039
cellular lipid metabolic process GO:0044255 323 0.038
inorganic ion transmembrane transport GO:0098660 234 0.037
cardiac muscle tissue development GO:0048738 130 0.037
regulation of neurotransmitter levels GO:0001505 87 0.037
regulation of system process GO:0044057 200 0.037
action potential GO:0001508 78 0.037
muscle tissue development GO:0060537 308 0.037
metal ion homeostasis GO:0055065 189 0.036
membrane organization GO:0061024 245 0.035
regulation of cell motility GO:2000145 236 0.035
cognition GO:0050890 149 0.035
multicellular organismal signaling GO:0035637 91 0.034
neuronal action potential GO:0019228 54 0.034
urogenital system development GO:0001655 261 0.034
regulation of kinase activity GO:0043549 249 0.033
regulation of cell projection organization GO:0031344 206 0.032
positive regulation of nervous system development GO:0051962 221 0.032
nucleotide metabolic process GO:0009117 332 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.032
anion transport GO:0006820 177 0.031
regulation of cell activation GO:0050865 289 0.031
regulation of cytokine production GO:0001817 266 0.031
lipid biosynthetic process GO:0008610 179 0.031
small molecule biosynthetic process GO:0044283 132 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
Mouse
carbohydrate metabolic process GO:0005975 230 0.030
peptidyl amino acid modification GO:0018193 336 0.030
heart contraction GO:0060047 93 0.030
response to organonitrogen compound GO:0010243 246 0.029
cellular chemical homeostasis GO:0055082 215 0.029
circulatory system process GO:0003013 197 0.028
purine containing compound metabolic process GO:0072521 311 0.028
cellular carbohydrate metabolic process GO:0044262 119 0.028
forebrain development GO:0030900 302 0.028
Mouse
amino acid transport GO:0006865 61 0.028
cation homeostasis GO:0055080 212 0.027
anatomical structure homeostasis GO:0060249 145 0.027
regulation of transferase activity GO:0051338 263 0.027
divalent metal ion transport GO:0070838 172 0.027
regulation of ion transport GO:0043269 215 0.026
nitrogen compound transport GO:0071705 271 0.026
neuron neuron synaptic transmission GO:0007270 69 0.026
memory GO:0007613 58 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of transmembrane transport GO:0034762 128 0.025
ras protein signal transduction GO:0007265 77 0.025
synapse organization GO:0050808 125 0.025
Mouse
positive regulation of kinase activity GO:0033674 155 0.025
organic acid transport GO:0015849 101 0.024
chemotaxis GO:0006935 247 0.024
cellular calcium ion homeostasis GO:0006874 119 0.024
neurotransmitter transport GO:0006836 76 0.023
embryonic organ morphogenesis GO:0048562 276 0.023
learning or memory GO:0007611 148 0.023
ensheathment of neurons GO:0007272 76 0.023
heart process GO:0003015 94 0.023
ribose phosphate metabolic process GO:0019693 291 0.022
regulation of protein kinase activity GO:0045859 232 0.022
fertilization GO:0009566 127 0.022
organelle localization GO:0051640 179 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
myotube cell development GO:0014904 60 0.022
hexose metabolic process GO:0019318 98 0.022
regulation of muscle tissue development GO:1901861 97 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
sensory perception GO:0007600 245 0.022
regulation of neuron differentiation GO:0045664 281 0.022
tissue remodeling GO:0048771 102 0.022
regulation of body fluid levels GO:0050878 162 0.022
cellular metal ion homeostasis GO:0006875 151 0.021
calcium ion homeostasis GO:0055074 127 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
striated muscle cell development GO:0055002 125 0.021
muscle cell development GO:0055001 133 0.021
exocytosis GO:0006887 121 0.021
ossification GO:0001503 216 0.021
regulation of secretion by cell GO:1903530 249 0.021
regulation of blood pressure GO:0008217 93 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
regulation of resting membrane potential GO:0060075 3 0.020
connective tissue development GO:0061448 179 0.020
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.020
positive regulation of protein modification process GO:0031401 299 0.020
cytokine production GO:0001816 319 0.020
single fertilization GO:0007338 82 0.020
negative regulation of molecular function GO:0044092 258 0.020
divalent inorganic cation transport GO:0072511 178 0.020
maintenance of location GO:0051235 89 0.020
cytoplasmic transport GO:0016482 234 0.020
response to organic cyclic compound GO:0014070 198 0.020
regulation of mapk cascade GO:0043408 248 0.019
axonogenesis GO:0007409 274 0.019
macromolecule catabolic process GO:0009057 281 0.019
positive regulation of cell death GO:0010942 224 0.019
tissue homeostasis GO:0001894 115 0.019
regulation of voltage gated calcium channel activity GO:1901385 4 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
cardiac muscle contraction GO:0060048 32 0.019
skeletal muscle organ development GO:0060538 163 0.019
carboxylic acid transport GO:0046942 100 0.019
wound healing GO:0042060 157 0.019
regulation of cell migration GO:0030334 219 0.019
lipid localization GO:0010876 126 0.019
positive regulation of transferase activity GO:0051347 167 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.018
camera type eye development GO:0043010 266 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
rap protein signal transduction GO:0032486 3 0.018
regulation of response to wounding GO:1903034 189 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
phospholipid metabolic process GO:0006644 87 0.018
skeletal muscle fiber development GO:0048741 58 0.018
respiratory system development GO:0060541 190 0.018
regulation of lipid metabolic process GO:0019216 118 0.018
extracellular matrix organization GO:0030198 147 0.018
Mouse
regulation of synaptic plasticity GO:0048167 87 0.018
regulation of feeding behavior GO:0060259 3 0.018
skeletal system morphogenesis GO:0048705 203 0.018
Mouse
learning GO:0007612 98 0.018
regulation of anatomical structure size GO:0090066 178 0.018
regulation of cell cycle GO:0051726 281 0.018
fatty acid metabolic process GO:0006631 121 0.018
regulation of secretion GO:0051046 274 0.018
l amino acid transport GO:0015807 32 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
cellular ion homeostasis GO:0006873 165 0.017
aromatic compound catabolic process GO:0019439 286 0.017
regulation of muscle system process GO:0090257 80 0.017
leukocyte differentiation GO:0002521 342 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
protein catabolic process GO:0030163 221 0.017
regulation of heart contraction GO:0008016 77 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
blood vessel morphogenesis GO:0048514 285 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
dna metabolic process GO:0006259 303 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
regulation of metal ion transport GO:0010959 106 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
locomotory behavior GO:0007626 195 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
cell adhesion GO:0007155 329 0.017
myotube differentiation GO:0014902 105 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
Mouse
fat cell differentiation GO:0045444 160 0.017
positive regulation of protein kinase activity GO:0045860 144 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
gland development GO:0048732 330 0.016
regulation of homeostatic process GO:0032844 182 0.016
apoptotic signaling pathway GO:0097190 306 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
rhythmic process GO:0048511 174 0.016
renal system development GO:0072001 225 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
stem cell differentiation GO:0048863 268 0.016
neurotransmitter secretion GO:0007269 62 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
cellular homeostasis GO:0019725 240 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
establishment of organelle localization GO:0051656 122 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
alpha amino acid metabolic process GO:1901605 59 0.015
protein localization to membrane GO:0072657 108 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
muscle cell differentiation GO:0042692 261 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
skeletal system development GO:0001501 356 0.015
Mouse
mitotic cell cycle GO:0000278 195 0.015
ribose phosphate biosynthetic process GO:0046390 59 0.015
heart morphogenesis GO:0003007 178 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.015
regulation of organelle organization GO:0033043 289 0.015
regulation of neuron projection development GO:0010975 169 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
sequestering of calcium ion GO:0051208 18 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
kidney development GO:0001822 213 0.015
muscle fiber development GO:0048747 76 0.015
positive regulation of leukocyte differentiation GO:1902107 86 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
regulation of engulfment of apoptotic cell GO:1901074 2 0.015
organic acid biosynthetic process GO:0016053 86 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
cell fate commitment GO:0045165 210 0.015
defense response to other organism GO:0098542 197 0.015
purine nucleotide biosynthetic process GO:0006164 65 0.015
axon ensheathment GO:0008366 76 0.014
glycoprotein metabolic process GO:0009100 116 0.014
Mouse
cellular protein catabolic process GO:0044257 155 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
regulation of protein localization GO:0032880 231 0.014
mesoderm development GO:0007498 100 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
neuron death GO:0070997 154 0.014
conditioned taste aversion GO:0001661 4 0.014
regulation of glucose metabolic process GO:0010906 60 0.014
regulation of ion homeostasis GO:2000021 64 0.014
compound eye development GO:0048749 1 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
cell growth GO:0016049 130 0.014
monosaccharide metabolic process GO:0005996 106 0.014
gonad development GO:0008406 141 0.014
cell maturation GO:0048469 127 0.014
nucleoside catabolic process GO:0009164 206 0.014
adult behavior GO:0030534 135 0.014
microtubule based process GO:0007017 236 0.014
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.014
meiotic cell cycle GO:0051321 122 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
vascular process in circulatory system GO:0003018 62 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
response to radiation GO:0009314 165 0.014
response to growth factor GO:0070848 198 0.014
developmental maturation GO:0021700 193 0.014
regulation of cellular response to stress GO:0080135 159 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
protein ubiquitination GO:0016567 171 0.013
glycerolipid metabolic process GO:0046486 122 0.013
regulation of multi organism process GO:0043900 111 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
positive regulation of vasoconstriction GO:0045907 4 0.013
angiogenesis GO:0001525 201 0.013
regulation of tube size GO:0035150 57 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
positive regulation of cellular ph reduction GO:0032849 2 0.013
male gamete generation GO:0048232 285 0.013
protein maturation GO:0051604 176 0.013
calcium ion transport GO:0006816 159 0.013
membrane lipid metabolic process GO:0006643 53 0.013
regulation of proteolysis GO:0030162 164 0.013
positive regulation of cell activation GO:0050867 158 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
dephosphorylation GO:0016311 129 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
negative regulation of neuron differentiation GO:0045665 101 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
plasma membrane organization GO:0007009 90 0.013
chondrocyte differentiation GO:0002062 72 0.013
Mouse
glucose homeostasis GO:0042593 128 0.013
leukocyte mediated immunity GO:0002443 174 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
establishment of vesicle localization GO:0051650 81 0.013
response to peptide GO:1901652 136 0.013
intracellular mrna localization GO:0008298 4 0.013
digestive system development GO:0055123 200 0.013
chromatin organization GO:0006325 206 0.013
endomembrane system organization GO:0010256 147 0.013
single organism cell adhesion GO:0098602 156 0.013
innate immune response GO:0045087 157 0.013
regulation of ion transmembrane transport GO:0034765 119 0.012
substantia nigra development GO:0021762 2 0.012
sensory perception of light stimulus GO:0050953 54 0.012
regulation of action potential GO:0098900 4 0.012
membrane lipid biosynthetic process GO:0046467 32 0.012
extracellular structure organization GO:0043062 148 0.012
Mouse
amino acid transmembrane transport GO:0003333 37 0.012
regulation of vasculature development GO:1901342 88 0.012
covalent chromatin modification GO:0016569 163 0.012
chromatin modification GO:0016568 187 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
regulation of cell cycle process GO:0010564 160 0.012
negative regulation of cell development GO:0010721 169 0.012
regulation of blood vessel size GO:0050880 56 0.012
positive regulation of cell development GO:0010720 237 0.012
regionalization GO:0003002 337 0.012
t cell activation GO:0042110 289 0.012
sensory organ morphogenesis GO:0090596 242 0.012
protein processing GO:0016485 163 0.012
response to insulin GO:0032868 100 0.012
cell type specific apoptotic process GO:0097285 268 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
muscle system process GO:0003012 141 0.012
multi multicellular organism process GO:0044706 109 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
response to extracellular stimulus GO:0009991 127 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
myelination GO:0042552 74 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
sphingolipid metabolic process GO:0006665 45 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
regulation of blood circulation GO:1903522 93 0.012
renal sodium ion transport GO:0003096 2 0.012
central nervous system neuron differentiation GO:0021953 162 0.011
vesicle localization GO:0051648 86 0.011
sensory system development GO:0048880 3 0.011
potassium ion transport GO:0006813 52 0.011
nuclear division GO:0000280 158 0.011
response to nutrient levels GO:0031667 109 0.011
cell division GO:0051301 120 0.011
spermatogenesis GO:0007283 284 0.011
b cell activation GO:0042113 161 0.011
dicarboxylic acid transport GO:0006835 29 0.011
phosphatidylinositol metabolic process GO:0046488 45 0.011
regulation of hormone levels GO:0010817 211 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
intracellular protein transport GO:0006886 204 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
nucleotide catabolic process GO:0009166 217 0.011
potassium ion homeostasis GO:0055075 4 0.011
response to acid chemical GO:0001101 111 0.011
regulation of map kinase activity GO:0043405 120 0.011
organophosphate catabolic process GO:0046434 232 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
organelle fission GO:0048285 170 0.011
cyclic nucleotide metabolic process GO:0009187 59 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
retina development in camera type eye GO:0060041 119 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
tube formation GO:0035148 140 0.011
nuclear transport GO:0051169 139 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
negative regulation of protein modification process GO:0031400 163 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
sulfur compound metabolic process GO:0006790 100 0.011
regulation of cellular component size GO:0032535 121 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
respiratory tube development GO:0030323 167 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
neural tube development GO:0021915 160 0.011
cartilage development GO:0051216 140 0.011
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.011
regulation of systemic arterial blood pressure GO:0003073 61 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
nucleoside metabolic process GO:0009116 246 0.011
gastrulation GO:0007369 116 0.011
synaptic vesicle transport GO:0048489 57 0.011
sodium ion transmembrane transport GO:0035725 49 0.011
oocyte construction GO:0007308 2 0.010
appendage development GO:0048736 166 0.010
pallium development GO:0021543 120 0.010
Mouse
regulation of cell growth GO:0001558 91 0.010
sequestering of metal ion GO:0051238 19 0.010
regulation of transporter activity GO:0032409 57 0.010
meiotic nuclear division GO:0007126 115 0.010
telencephalon development GO:0021537 186 0.010
Mouse
bone development GO:0060348 120 0.010
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.010
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.010
organic hydroxy compound transport GO:0015850 93 0.010
regulation of hydrolase activity GO:0051336 246 0.010
germ cell development GO:0007281 185 0.010
interleukin 8 production GO:0032637 4 0.010
axon guidance GO:0007411 141 0.010
sulfur compound biosynthetic process GO:0044272 37 0.010
lipid transport GO:0006869 98 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
purine containing compound catabolic process GO:0072523 213 0.010
feeding behavior GO:0007631 62 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010
gliogenesis GO:0042063 141 0.010
blastocyst development GO:0001824 80 0.010
protein localization to organelle GO:0033365 185 0.010
negative regulation of organelle organization GO:0010639 90 0.010
ceramide metabolic process GO:0006672 31 0.010
glial cell differentiation GO:0010001 131 0.010

Hapln4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
nervous system disease DOID:863 0 0.013
disease of anatomical entity DOID:7 0 0.013