Mus musculus

8 known processes

Npc1l1

NPC1-like 1

(Aliases: Gm243,9130221N23Rik)

Npc1l1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 266 0.125
ion transmembrane transport GO:0034220 361 0.122
transmembrane transport GO:0055085 412 0.102
inorganic cation transmembrane transport GO:0098662 207 0.075
cellular amino acid metabolic process GO:0006520 103 0.073
anion transport GO:0006820 177 0.064
cation transport GO:0006812 399 0.054
cellular amine metabolic process GO:0044106 44 0.054
peptidyl amino acid modification GO:0018193 336 0.052
aromatic compound catabolic process GO:0019439 286 0.049
cellular lipid metabolic process GO:0044255 323 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
inorganic ion transmembrane transport GO:0098660 234 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.045
male gamete generation GO:0048232 285 0.043
ribose phosphate metabolic process GO:0019693 291 0.040
organic cyclic compound catabolic process GO:1901361 295 0.039
muscle cell differentiation GO:0042692 261 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
organic anion transport GO:0015711 137 0.037
muscle tissue development GO:0060537 308 0.037
amine metabolic process GO:0009308 45 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
sodium ion transmembrane transport GO:0035725 49 0.034
purine containing compound metabolic process GO:0072521 311 0.034
heterocycle catabolic process GO:0046700 280 0.034
sodium ion transport GO:0006814 73 0.033
germ cell development GO:0007281 185 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
leukocyte differentiation GO:0002521 342 0.032
striated muscle tissue development GO:0014706 293 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
cellular ketone metabolic process GO:0042180 84 0.031
synaptic transmission GO:0007268 329 0.031
nucleotide metabolic process GO:0009117 332 0.031
immune effector process GO:0002252 321 0.031
nitrogen compound transport GO:0071705 271 0.030
anion transmembrane transport GO:0098656 71 0.029
spermatogenesis GO:0007283 284 0.029
regulation of leukocyte differentiation GO:1902105 159 0.029
ribonucleotide metabolic process GO:0009259 291 0.028
purine nucleotide metabolic process GO:0006163 302 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
lipid localization GO:0010876 126 0.026
Human Mouse Worm
nucleoside catabolic process GO:0009164 206 0.025
striated muscle cell development GO:0055002 125 0.025
lipid homeostasis GO:0055088 63 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
negative regulation of molecular function GO:0044092 258 0.024
small molecule biosynthetic process GO:0044283 132 0.024
Human
organic acid transport GO:0015849 101 0.024
regulation of cellular ketone metabolic process GO:0010565 66 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
regulation of ion transport GO:0043269 215 0.024
organophosphate catabolic process GO:0046434 232 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
blood circulation GO:0008015 195 0.023
regulation of secretion GO:0051046 274 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
macromolecule catabolic process GO:0009057 281 0.023
nucleotide catabolic process GO:0009166 217 0.023
camera type eye development GO:0043010 266 0.023
regulation of cell projection organization GO:0031344 206 0.023
myeloid cell differentiation GO:0030099 233 0.023
lipid transport GO:0006869 98 0.022
Human Mouse Worm
carbohydrate derivative catabolic process GO:1901136 231 0.022
ras protein signal transduction GO:0007265 77 0.022
carboxylic acid transport GO:0046942 100 0.022
cytoplasmic transport GO:0016482 234 0.022
sterol homeostasis GO:0055092 45 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
epithelial cell development GO:0002064 159 0.021
circulatory system process GO:0003013 197 0.021
homeostasis of number of cells GO:0048872 210 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
mitotic cell cycle GO:0000278 195 0.020
regulation of protein localization GO:0032880 231 0.020
regulation of protein kinase activity GO:0045859 232 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
lipid biosynthetic process GO:0008610 179 0.020
Human
t cell activation GO:0042110 289 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
maintenance of location GO:0051235 89 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
cholesterol homeostasis GO:0042632 44 0.019
dna metabolic process GO:0006259 303 0.019
phospholipid metabolic process GO:0006644 87 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
regulation of muscle tissue development GO:1901861 97 0.019
nucleoside metabolic process GO:0009116 246 0.019
regulation of cell cycle GO:0051726 281 0.019
skeletal system development GO:0001501 356 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
regulation of transmembrane transport GO:0034762 128 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
divalent inorganic cation transport GO:0072511 178 0.018
cell adhesion GO:0007155 329 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
defense response to other organism GO:0098542 197 0.018
cardiac muscle tissue development GO:0048738 130 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
regionalization GO:0003002 337 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
innate immune response GO:0045087 157 0.018
myotube differentiation GO:0014902 105 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
Mouse
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
nucleoside monophosphate metabolic process GO:0009123 85 0.017
fertilization GO:0009566 127 0.017
lymphocyte differentiation GO:0030098 242 0.017
regulation of organelle organization GO:0033043 289 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
positive regulation of protein modification process GO:0031401 299 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
positive regulation of ion transport GO:0043270 65 0.017
purine containing compound catabolic process GO:0072523 213 0.016
ossification GO:0001503 216 0.016
regulation of cytokine production GO:0001817 266 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
glycoprotein metabolic process GO:0009100 116 0.016
Mouse
membrane organization GO:0061024 245 0.016
sulfur compound metabolic process GO:0006790 100 0.016
organelle fission GO:0048285 170 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
cellular homeostasis GO:0019725 240 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
apoptotic signaling pathway GO:0097190 306 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
multicellular organism growth GO:0035264 161 0.016
sensory perception GO:0007600 245 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
Human Mouse
calcium ion transport GO:0006816 159 0.016
organic hydroxy compound transport GO:0015850 93 0.016
Human Mouse Worm
response to nutrient levels GO:0031667 109 0.015
Mouse
microtubule based process GO:0007017 236 0.015
response to organonitrogen compound GO:0010243 246 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
muscle cell development GO:0055001 133 0.015
alcohol metabolic process GO:0006066 116 0.015
Human
regulation of cellular component biogenesis GO:0044087 181 0.015
amino acid transport GO:0006865 61 0.015
mucopolysaccharide metabolic process GO:1903510 25 0.015
regulation of neuron differentiation GO:0045664 281 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
sterol transport GO:0015918 38 0.015
Human Mouse Worm
positive regulation of cell development GO:0010720 237 0.015
response to organic cyclic compound GO:0014070 198 0.015
Mouse
inorganic anion transport GO:0015698 43 0.015
dephosphorylation GO:0016311 129 0.015
protein catabolic process GO:0030163 221 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
protein ubiquitination GO:0016567 171 0.014
regulation of transferase activity GO:0051338 263 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
regulation of t cell activation GO:0050863 170 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
glycerolipid metabolic process GO:0046486 122 0.014
peptidyl serine modification GO:0018209 83 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
meiotic cell cycle GO:0051321 122 0.014
cytokine production GO:0001816 319 0.014
skeletal muscle organ development GO:0060538 163 0.014
renal system development GO:0072001 225 0.014
development of primary sexual characteristics GO:0045137 143 0.014
skin development GO:0043588 220 0.014
cellular chemical homeostasis GO:0055082 215 0.014
mitotic cell cycle process GO:1903047 159 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
intracellular protein transport GO:0006886 204 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
urogenital system development GO:0001655 261 0.014
appendage morphogenesis GO:0035107 149 0.013
epidermis development GO:0008544 187 0.013
organelle assembly GO:0070925 177 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of neuron projection development GO:0010975 169 0.013
cellular protein complex assembly GO:0043623 116 0.013
single organism cell adhesion GO:0098602 156 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
response to lipopolysaccharide GO:0032496 128 0.013
nuclear division GO:0000280 158 0.013
rhythmic process GO:0048511 174 0.013
endocytosis GO:0006897 168 0.013
Mouse
negative regulation of protein modification process GO:0031400 163 0.013
blood vessel morphogenesis GO:0048514 285 0.013
cell activation involved in immune response GO:0002263 126 0.013
regulation of cell activation GO:0050865 289 0.013
immune response activating signal transduction GO:0002757 116 0.013
cellular ion homeostasis GO:0006873 165 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
regulation of cell cycle process GO:0010564 160 0.013
response to extracellular stimulus GO:0009991 127 0.013
Mouse
response to oxygen levels GO:0070482 62 0.013
placenta development GO:0001890 140 0.013
regulation of feeding behavior GO:0060259 3 0.013
cardiocyte differentiation GO:0035051 87 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
oocyte construction GO:0007308 2 0.013
respiratory system development GO:0060541 190 0.013
skeletal muscle fiber development GO:0048741 58 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
atp catabolic process GO:0006200 55 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of t cell differentiation GO:0045580 83 0.012
amino acid transmembrane transport GO:0003333 37 0.012
lateral inhibition GO:0046331 1 0.012
regulation of blood pressure GO:0008217 93 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
Mouse
adult behavior GO:0030534 135 0.012
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
myosin filament assembly GO:0031034 2 0.012
response to acid chemical GO:0001101 111 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
sensory organ morphogenesis GO:0090596 242 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
Mouse
positive regulation of programmed cell death GO:0043068 218 0.012
single fertilization GO:0007338 82 0.012
tissue homeostasis GO:0001894 115 0.012
response to inorganic substance GO:0010035 96 0.012
regulation of sterol transport GO:0032371 17 0.012
monosaccharide transport GO:0015749 58 0.012
regulation of secretion by cell GO:1903530 249 0.012
rho protein signal transduction GO:0007266 32 0.012
muscle system process GO:0003012 141 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
positive regulation of cell death GO:0010942 224 0.012
regulation of transporter activity GO:0032409 57 0.012
regulation of mapk cascade GO:0043408 248 0.012
oxidation reduction process GO:0055114 342 0.012
atp metabolic process GO:0046034 75 0.012
digestive system development GO:0055123 200 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
tissue remodeling GO:0048771 102 0.011
membrane lipid metabolic process GO:0006643 53 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
gonad development GO:0008406 141 0.011
negative regulation of myeloid cell differentiation GO:0045638 38 0.011
response to oxidative stress GO:0006979 123 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
cholesterol transport GO:0030301 38 0.011
Human Mouse Worm
cellular protein catabolic process GO:0044257 155 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of system process GO:0044057 200 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
negative regulation of cell development GO:0010721 169 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
negative regulation of neuron death GO:1901215 98 0.011
endomembrane system organization GO:0010256 147 0.011
chemotaxis GO:0006935 247 0.011
learning or memory GO:0007611 148 0.011
regulation of hormone levels GO:0010817 211 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
alpha beta t cell differentiation GO:0046632 69 0.011
cognition GO:0050890 149 0.011
cell fate commitment GO:0045165 210 0.011
sequestering of calcium ion GO:0051208 18 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
protein maturation GO:0051604 176 0.011
gland development GO:0048732 330 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
response to peptide GO:1901652 136 0.011
cell type specific apoptotic process GO:0097285 268 0.011
regulation of cell adhesion GO:0030155 154 0.011
sphingolipid metabolic process GO:0006665 45 0.011
protein processing GO:0016485 163 0.011
cellular response to lipid GO:0071396 145 0.011
Mouse
positive regulation of cell activation GO:0050867 158 0.011
carbohydrate metabolic process GO:0005975 230 0.011
Mouse
connective tissue development GO:0061448 179 0.011
extracellular matrix organization GO:0030198 147 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
organelle localization GO:0051640 179 0.010
cellular potassium ion transport GO:0071804 43 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010
regulation of voltage gated calcium channel activity GO:1901385 4 0.010
regulation of protein complex assembly GO:0043254 83 0.010
mapk cascade GO:0000165 281 0.010
regulation of membrane potential GO:0042391 192 0.010
chromatin organization GO:0006325 206 0.010
cation homeostasis GO:0055080 212 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
negative regulation of immune system process GO:0002683 209 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010

Npc1l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.012
cardiovascular system disease DOID:1287 0 0.011