Mus musculus

0 known processes

Ubr4

ubiquitin protein ligase E3 component n-recognin 4

(Aliases: 1810009A16Rik,A930005E13Rik,RBAF600,p600,D930005K06Rik,N28143,Gm1032,Gm1666,Zubr1,mKIAA0462)

Ubr4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.273
protein modification by small protein conjugation GO:0032446 187 0.163
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.147
protein ubiquitination GO:0016567 171 0.147
Human
negative regulation of cell proliferation GO:0008285 296 0.139
modification dependent macromolecule catabolic process GO:0043632 133 0.124
Human
chromatin modification GO:0016568 187 0.113
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.111
microtubule cytoskeleton organization GO:0000226 157 0.096
protein modification by small protein conjugation or removal GO:0070647 207 0.095
Human
regionalization GO:0003002 337 0.095
microtubule based process GO:0007017 236 0.094
protein localization to organelle GO:0033365 185 0.085
oocyte construction GO:0007308 2 0.075
axon cargo transport GO:0008088 33 0.074
cytoplasmic transport GO:0016482 234 0.067
oocyte axis specification GO:0007309 2 0.066
negative regulation of protein metabolic process GO:0051248 282 0.064
covalent chromatin modification GO:0016569 163 0.062
negative regulation of cellular protein metabolic process GO:0032269 247 0.060
small gtpase mediated signal transduction GO:0007264 97 0.059
dna metabolic process GO:0006259 303 0.058
cellular protein catabolic process GO:0044257 155 0.057
Human
germ cell development GO:0007281 185 0.057
intracellular mrna localization GO:0008298 4 0.056
regulation of organelle organization GO:0033043 289 0.055
axonogenesis GO:0007409 274 0.054
positive regulation of dna templated transcription elongation GO:0032786 2 0.054
regulation of neuron projection development GO:0010975 169 0.054
locomotory behavior GO:0007626 195 0.053
positive regulation of cell development GO:0010720 237 0.052
negative regulation of cellular component organization GO:0051129 194 0.052
protein localization to membrane GO:0072657 108 0.052
nucleotide metabolic process GO:0009117 332 0.050
regulation of neuron differentiation GO:0045664 281 0.048
cellular homeostasis GO:0019725 240 0.048
protein catabolic process GO:0030163 221 0.047
Human
ribonucleotide metabolic process GO:0009259 291 0.047
intracellular protein transport GO:0006886 204 0.046
chromatin organization GO:0006325 206 0.046
multicellular organism growth GO:0035264 161 0.045
protein processing GO:0016485 163 0.045
cell growth GO:0016049 130 0.045
regulation of ras protein signal transduction GO:0046578 114 0.044
organelle localization GO:0051640 179 0.044
primary neural tube formation GO:0014020 95 0.044
cellular macromolecule catabolic process GO:0044265 206 0.044
Human
neuron projection guidance GO:0097485 141 0.043
pole plasm assembly GO:0007315 2 0.043
cell fate commitment GO:0045165 210 0.043
nucleoside catabolic process GO:0009164 206 0.042
ribonucleotide catabolic process GO:0009261 208 0.042
cilium morphogenesis GO:0060271 102 0.042
regulation of hydrolase activity GO:0051336 246 0.040
rab protein signal transduction GO:0032482 1 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.038
synaptic transmission GO:0007268 329 0.037
chemotaxis GO:0006935 247 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
regulation of reactive oxygen species metabolic process GO:2000377 40 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
ear development GO:0043583 200 0.036
maintenance of location GO:0051235 89 0.036
neural tube development GO:0021915 160 0.034
microtubule based movement GO:0007018 84 0.034
endocytosis GO:0006897 168 0.033
positive regulation of protein modification process GO:0031401 299 0.033
inclusion body assembly GO:0070841 3 0.033
macromolecule catabolic process GO:0009057 281 0.033
Human
cellular response to dna damage stimulus GO:0006974 207 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.032
positive regulation of nervous system development GO:0051962 221 0.032
mitotic cytokinesis GO:0000281 4 0.032
aromatic compound catabolic process GO:0019439 286 0.032
adult behavior GO:0030534 135 0.032
segmentation GO:0035282 93 0.032
protein maturation GO:0051604 176 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
mitotic cell cycle process GO:1903047 159 0.031
dna repair GO:0006281 107 0.031
regulation of proteolysis GO:0030162 164 0.031
purine nucleoside catabolic process GO:0006152 205 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
neural tube closure GO:0001843 90 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.029
Human
negative regulation of intracellular signal transduction GO:1902532 167 0.029
establishment or maintenance of cell polarity GO:0007163 86 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.029
cytoskeleton dependent intracellular transport GO:0030705 50 0.029
histone deubiquitination GO:0016578 2 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
cellular chemical homeostasis GO:0055082 215 0.028
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.028
microtubule based transport GO:0010970 50 0.028
positive regulation of hydrolase activity GO:0051345 148 0.027
regulation of removal of superoxide radicals GO:2000121 4 0.027
membrane organization GO:0061024 245 0.027
positive regulation of neuron projection development GO:0010976 79 0.027
negative regulation of protein maturation GO:1903318 79 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
placenta development GO:0001890 140 0.026
cellular ketone metabolic process GO:0042180 84 0.026
kidney development GO:0001822 213 0.026
meiotic cell cycle process GO:1903046 77 0.026
sensory organ morphogenesis GO:0090596 242 0.026
cellular carbohydrate metabolic process GO:0044262 119 0.026
neuron migration GO:0001764 122 0.025
rhythmic process GO:0048511 174 0.025
cellular amine metabolic process GO:0044106 44 0.025
regulation of cell projection organization GO:0031344 206 0.025
meiosis i GO:0007127 60 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
response to extracellular stimulus GO:0009991 127 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.024
gene silencing by mirna GO:0035195 10 0.024
organelle fission GO:0048285 170 0.024
establishment of protein localization to organelle GO:0072594 118 0.024
plasma membrane organization GO:0007009 90 0.024
cell recognition GO:0008037 83 0.024
neural tube formation GO:0001841 108 0.023
tube formation GO:0035148 140 0.023
negative regulation of molecular function GO:0044092 258 0.023
skin development GO:0043588 220 0.023
female gamete generation GO:0007292 74 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
negative regulation of microtubule depolymerization GO:0007026 13 0.023
nucleus localization GO:0051647 20 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
Human
epithelial cell development GO:0002064 159 0.023
fertilization GO:0009566 127 0.023
epidermis development GO:0008544 187 0.023
reactive oxygen species metabolic process GO:0072593 84 0.022
epithelial tube formation GO:0072175 130 0.022
response to endoplasmic reticulum stress GO:0034976 53 0.022
oocyte differentiation GO:0009994 35 0.022
regulation of histone methylation GO:0031060 30 0.022
positive regulation of cell projection organization GO:0031346 95 0.022
chromatin assembly GO:0031497 13 0.022
single fertilization GO:0007338 82 0.021
regulation of cellular response to stress GO:0080135 159 0.021
anion transport GO:0006820 177 0.021
gonad development GO:0008406 141 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
regulation of secretion GO:0051046 274 0.021
organelle assembly GO:0070925 177 0.021
nuclear division GO:0000280 158 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
Human
macromolecule methylation GO:0043414 120 0.021
meiotic cell cycle GO:0051321 122 0.020
tube closure GO:0060606 91 0.020
regulation of cell growth GO:0001558 91 0.020
peptidyl lysine modification GO:0018205 77 0.020
inner cell mass cell proliferation GO:0001833 15 0.020
negative regulation of growth GO:0045926 99 0.020
negative regulation of synapse assembly GO:0051964 3 0.020
cell division GO:0051301 120 0.019
protein depolymerization GO:0051261 34 0.019
renal system development GO:0072001 225 0.019
histone modification GO:0016570 159 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
leukocyte differentiation GO:0002521 342 0.019
negative regulation of protein processing GO:0010955 79 0.019
regulation of protein processing GO:0070613 96 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
protein acylation GO:0043543 64 0.019
regulation of anatomical structure size GO:0090066 178 0.018
eye photoreceptor cell differentiation GO:0001754 41 0.018
response to oxidative stress GO:0006979 123 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
cytoplasmic microtubule organization GO:0031122 14 0.018
notch signaling pathway GO:0007219 71 0.018
pharynx development GO:0060465 1 0.018
cilium assembly GO:0042384 81 0.018
methylation GO:0032259 134 0.018
spermatogenesis GO:0007283 284 0.018
protein methylation GO:0006479 81 0.018
wnt signaling pathway GO:0016055 188 0.018
cell junction organization GO:0034330 77 0.017
dephosphorylation GO:0016311 129 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of histone modification GO:0031056 56 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
positive regulation of wnt signaling pathway GO:0030177 45 0.017
oocyte anterior posterior axis specification GO:0007314 2 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
regulation of cell motility GO:2000145 236 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
regulation of chromosome organization GO:0033044 83 0.017
histone lysine methylation GO:0034968 50 0.016
forebrain development GO:0030900 302 0.016
synaptonemal complex assembly GO:0007130 13 0.016
regulation of extent of cell growth GO:0061387 52 0.016
establishment of organelle localization GO:0051656 122 0.016
neural precursor cell proliferation GO:0061351 121 0.016
respiratory system development GO:0060541 190 0.016
rna localization GO:0006403 23 0.016
purine containing compound metabolic process GO:0072521 311 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
bone development GO:0060348 120 0.016
telencephalon development GO:0021537 186 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
nitrogen compound transport GO:0071705 271 0.016
stem cell differentiation GO:0048863 268 0.016
cation transport GO:0006812 399 0.016
establishment of planar polarity GO:0001736 28 0.016
negative regulation of protein modification process GO:0031400 163 0.016
glucose homeostasis GO:0042593 128 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
protein targeting GO:0006605 143 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
digestive system development GO:0055123 200 0.016
circadian rhythm GO:0007623 114 0.016
heterocycle catabolic process GO:0046700 280 0.016
fat cell differentiation GO:0045444 160 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
heart morphogenesis GO:0003007 178 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
regulation of toll signaling pathway GO:0008592 1 0.015
response to topologically incorrect protein GO:0035966 25 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
histone h4 k16 acetylation GO:0043984 3 0.015
embryonic placenta development GO:0001892 98 0.015
skeletal system morphogenesis GO:0048705 203 0.015
amine metabolic process GO:0009308 45 0.015
regulation of protein maturation GO:1903317 96 0.015
mitotic cell cycle GO:0000278 195 0.015
negative regulation of nervous system development GO:0051961 156 0.015
carbohydrate metabolic process GO:0005975 230 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
developmental maturation GO:0021700 193 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
respiratory tube development GO:0030323 167 0.014
male gamete generation GO:0048232 285 0.014
response to reactive oxygen species GO:0000302 56 0.014
transmission of nerve impulse GO:0019226 76 0.014
learning or memory GO:0007611 148 0.014
neuronal action potential GO:0019228 54 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
rna processing GO:0006396 105 0.014
olfactory learning GO:0008355 2 0.014
defecation GO:0030421 1 0.014
cognition GO:0050890 149 0.014
protein localization to plasma membrane GO:0072659 57 0.014
establishment of spindle orientation GO:0051294 15 0.014
negative regulation of proteolysis GO:0045861 74 0.014
neuron projection extension GO:1990138 64 0.014
transmembrane transport GO:0055085 412 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
cell maturation GO:0048469 127 0.013
placenta blood vessel development GO:0060674 31 0.013
regulation of cell cycle GO:0051726 281 0.013
ossification GO:0001503 216 0.013
positive regulation of binding GO:0051099 49 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
b cell activation GO:0042113 161 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
retina development in camera type eye GO:0060041 119 0.013
nucleotide catabolic process GO:0009166 217 0.013
cellular response to topologically incorrect protein GO:0035967 25 0.013
response to unfolded protein GO:0006986 21 0.013
establishment of meiotic spindle orientation GO:0051296 1 0.013
regulation of chromatin organization GO:1902275 57 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
purine containing compound catabolic process GO:0072523 213 0.013
protein localization to nucleus GO:0034504 121 0.013
regulation of protein catabolic process GO:0042176 108 0.013
lipid localization GO:0010876 126 0.013
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.013
exocytosis GO:0006887 121 0.012
response to organonitrogen compound GO:0010243 246 0.012
histone methylation GO:0016571 71 0.012
hindbrain development GO:0030902 128 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
establishment of synaptic vesicle localization GO:0097480 57 0.012
lymphocyte differentiation GO:0030098 242 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
regulation of protein ubiquitination GO:0031396 52 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
molting cycle GO:0042303 90 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
lateral inhibition GO:0046331 1 0.012
axon guidance GO:0007411 141 0.012
negative regulation of organelle organization GO:0010639 90 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
spindle organization GO:0007051 28 0.012
meiotic nuclear division GO:0007126 115 0.012
male meiosis GO:0007140 37 0.012
myeloid cell differentiation GO:0030099 233 0.012
cellular response to oxidative stress GO:0034599 76 0.012
male courtship behavior GO:0008049 2 0.012
regulation of microtubule cytoskeleton organization GO:0070507 37 0.012
action potential GO:0001508 78 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
regulation of microtubule based process GO:0032886 52 0.012
cell adhesion GO:0007155 329 0.012
biomineral tissue development GO:0031214 64 0.011
regulation of transferase activity GO:0051338 263 0.011
striated muscle tissue development GO:0014706 293 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
spermatid development GO:0007286 108 0.011
regulation of response to wounding GO:1903034 189 0.011
oocyte development GO:0048599 33 0.011
regulation of hormone secretion GO:0046883 88 0.011
protein dna complex subunit organization GO:0071824 28 0.011
cellular ion homeostasis GO:0006873 165 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
myeloid cell homeostasis GO:0002262 114 0.011
response to oxygen levels GO:0070482 62 0.011
skeletal system development GO:0001501 356 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
posttranslational protein targeting to membrane GO:0006620 2 0.011
myotube differentiation GO:0014902 105 0.011
stem cell fate specification GO:0048866 3 0.011
regulation of hormone levels GO:0010817 211 0.011
phagocytosis GO:0006909 66 0.011
dendrite development GO:0016358 115 0.011
extracellular matrix organization GO:0030198 147 0.011
vacuole organization GO:0007033 38 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
positive regulation of cell growth GO:0030307 33 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
metencephalon development GO:0022037 89 0.011
peptidyl lysine acetylation GO:0018394 45 0.011
regulation of membrane potential GO:0042391 192 0.011
mesodermal cell migration GO:0008078 4 0.011
regulation of cell adhesion GO:0030155 154 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
negative regulation of protein complex disassembly GO:0043242 22 0.011
apoptotic signaling pathway GO:0097190 306 0.010
cellular protein complex assembly GO:0043623 116 0.010
camera type eye development GO:0043010 266 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.010
cell type specific apoptotic process GO:0097285 268 0.010
muscle tissue development GO:0060537 308 0.010
regulation of homeostatic process GO:0032844 182 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
internal peptidyl lysine acetylation GO:0018393 42 0.010
cellularization GO:0007349 1 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
mesoderm development GO:0007498 100 0.010
actin cytoskeleton organization GO:0030036 220 0.010
spermatid differentiation GO:0048515 115 0.010
wound healing GO:0042060 157 0.010
sequestering of calcium ion GO:0051208 18 0.010
regulation of transcription during meiosis GO:0051037 1 0.010

Ubr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.130
nervous system disease DOID:863 0 0.130
neuromuscular disease DOID:440 0 0.062
neuropathy DOID:870 0 0.062
central nervous system disease DOID:331 0 0.034
charcot marie tooth disease DOID:10595 0 0.029
neurodegenerative disease DOID:1289 0 0.013