Mus musculus

5 known processes

Ppp2ca

protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform

(Aliases: PP2A,R75353)

Ppp2ca biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dephosphorylation GO:0016311 129 0.927
Rat Fly
regulation of apoptotic signaling pathway GO:2001233 197 0.926
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.923
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.900
gonad development GO:0008406 141 0.864
negative regulation of cellular protein metabolic process GO:0032269 247 0.853
Rat
negative regulation of phosphorus metabolic process GO:0010563 184 0.842
Rat
chromosome segregation GO:0007059 48 0.729
Fly
oogenesis GO:0048477 56 0.710
Fly
pole plasm assembly GO:0007315 2 0.668
negative regulation of protein metabolic process GO:0051248 282 0.644
Rat
regulation of protein dephosphorylation GO:0035304 4 0.632
Rat
regionalization GO:0003002 337 0.621
negative regulation of apoptotic signaling pathway GO:2001234 104 0.601
genitalia development GO:0048806 37 0.565
development of primary sexual characteristics GO:0045137 143 0.561
regulation of dephosphorylation GO:0035303 18 0.543
Rat
hatching GO:0035188 4 0.530
nuclear division GO:0000280 158 0.526
Fly
apoptotic signaling pathway GO:0097190 306 0.493
organism emergence from protective structure GO:0071684 4 0.479
mesenchyme development GO:0060485 152 0.473
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.464
microtubule cytoskeleton organization GO:0000226 157 0.448
Worm Fly
purine nucleoside catabolic process GO:0006152 205 0.443
spermatid differentiation GO:0048515 115 0.432
cellular macromolecule catabolic process GO:0044265 206 0.424
proteasomal protein catabolic process GO:0010498 98 0.403
endomembrane system organization GO:0010256 147 0.399
Worm
positive regulation of apoptotic process GO:0043065 217 0.382
Rat
thermosensory behavior GO:0040040 1 0.353
negative regulation of protein dephosphorylation GO:0035308 2 0.329
cellular response to dna damage stimulus GO:0006974 207 0.320
regulation of intracellular transport GO:0032386 159 0.311
Rat
chromatin organization GO:0006325 206 0.301
positive regulation of mapk cascade GO:0043410 170 0.300
regulation of cellular catabolic process GO:0031329 242 0.287
endocytosis GO:0006897 168 0.286
Fly
olfactory learning GO:0008355 2 0.270
oocyte development GO:0048599 33 0.266
negative regulation of cellular component organization GO:0051129 194 0.260
Human
mapk cascade GO:0000165 281 0.260
negative regulation of phosphate metabolic process GO:0045936 184 0.259
Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.254
macromolecule catabolic process GO:0009057 281 0.254
Rat
spermatogenesis GO:0007283 284 0.251
regulation of protein stability GO:0031647 52 0.250
meiotic cell cycle GO:0051321 122 0.244
Worm
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.241
dna metabolic process GO:0006259 303 0.240
response to temperature stimulus GO:0009266 55 0.239
translation GO:0006412 93 0.237
spermatid development GO:0007286 108 0.236
negative regulation of dephosphorylation GO:0035305 9 0.236
oocyte axis specification GO:0007309 2 0.233
establishment or maintenance of cell polarity GO:0007163 86 0.229
Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.228
purine containing compound catabolic process GO:0072523 213 0.221
inclusion body assembly GO:0070841 3 0.219
oocyte construction GO:0007308 2 0.218
regulation of epidermal cell division GO:0010482 3 0.214
heterocycle catabolic process GO:0046700 280 0.213
protein ubiquitination GO:0016567 171 0.211
positive regulation of cell death GO:0010942 224 0.203
Rat
negative regulation of cell proliferation GO:0008285 296 0.198
Fly
nucleoside catabolic process GO:0009164 206 0.196
protein dna complex subunit organization GO:0071824 28 0.192
cellular protein catabolic process GO:0044257 155 0.175
ribonucleotide metabolic process GO:0009259 291 0.174
regulation of protein kinase activity GO:0045859 232 0.173
Human
nucleotide metabolic process GO:0009117 332 0.172
protein modification by small protein conjugation GO:0032446 187 0.172
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.171
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.170
male gamete generation GO:0048232 285 0.169
modification dependent macromolecule catabolic process GO:0043632 133 0.167
negative regulation of molecular function GO:0044092 258 0.166
Rat
regulation of organelle organization GO:0033043 289 0.162
axonogenesis GO:0007409 274 0.161
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.159
actin filament organization GO:0007015 113 0.158
Fly
organelle fission GO:0048285 170 0.157
Fly
regulation of protein complex assembly GO:0043254 83 0.153
chromatin modification GO:0016568 187 0.152
aggresome assembly GO:0070842 2 0.150
ribonucleoside metabolic process GO:0009119 245 0.149
response to organic cyclic compound GO:0014070 198 0.147
Rat
ribonucleoside catabolic process GO:0042454 206 0.144
small gtpase mediated signal transduction GO:0007264 97 0.144
purine ribonucleotide metabolic process GO:0009150 290 0.143
multi organism behavior GO:0051705 62 0.141
mitotic nuclear division GO:0007067 48 0.141
Fly
regulation of neuron projection development GO:0010975 169 0.137
cytoplasmic transport GO:0016482 234 0.132
Rat
glycogen metabolic process GO:0005977 32 0.128
positive regulation of apoptotic signaling pathway GO:2001235 95 0.127
germ cell development GO:0007281 185 0.127
Fly
single fertilization GO:0007338 82 0.126
Worm
purine nucleoside metabolic process GO:0042278 241 0.126
nucleotide catabolic process GO:0009166 217 0.126
fertilization GO:0009566 127 0.124
Worm
negative regulation of organelle organization GO:0010639 90 0.122
mitotic cell cycle GO:0000278 195 0.119
Worm Fly
purine ribonucleoside catabolic process GO:0046130 205 0.118
regulation of secretion by cell GO:1903530 249 0.118
cell maturation GO:0048469 127 0.118
cell division GO:0051301 120 0.118
Worm Fly
ribose phosphate metabolic process GO:0019693 291 0.116
stem cell development GO:0048864 219 0.115
Human
regulation of cellular response to stress GO:0080135 159 0.115
regulation of body fluid levels GO:0050878 162 0.114
positive regulation of programmed cell death GO:0043068 218 0.113
Rat
stem cell differentiation GO:0048863 268 0.113
Human
multi organism reproductive behavior GO:0044705 29 0.112
regulation of cell growth GO:0001558 91 0.111
organic cyclic compound catabolic process GO:1901361 295 0.111
rhythmic process GO:0048511 174 0.111
nucleoside monophosphate catabolic process GO:0009125 59 0.110
regulation of mapk cascade GO:0043408 248 0.110
multi multicellular organism process GO:0044706 109 0.107
erk1 and erk2 cascade GO:0070371 77 0.106
nucleobase containing small molecule metabolic process GO:0055086 352 0.104
mitotic cell cycle process GO:1903047 159 0.103
Worm Fly
protein catabolic process GO:0030163 221 0.103
Rat
maternal determination of anterior posterior axis embryo GO:0008358 2 0.102
rna processing GO:0006396 105 0.101
cognition GO:0050890 149 0.099
intracellular protein transport GO:0006886 204 0.098
Rat
positive regulation of dna templated transcription elongation GO:0032786 2 0.096
synaptic transmission GO:0007268 329 0.094
multicellular organismal reproductive behavior GO:0033057 23 0.091
ras protein signal transduction GO:0007265 77 0.089
nucleoside triphosphate catabolic process GO:0009143 205 0.088
gene silencing GO:0016458 38 0.087
regulation of cellular protein catabolic process GO:1903362 61 0.086
regulation of transferase activity GO:0051338 263 0.085
Human
cell growth GO:0016049 130 0.085
dna repair GO:0006281 107 0.085
protein localization to membrane GO:0072657 108 0.085
nucleoside phosphate catabolic process GO:1901292 222 0.083
intrinsic apoptotic signaling pathway GO:0097193 132 0.082
negative regulation of epithelial cell proliferation GO:0050680 64 0.082
keratinocyte development GO:0003334 10 0.081
cellular response to organonitrogen compound GO:0071417 145 0.081
Rat
epithelial to mesenchymal transition GO:0001837 47 0.080
Human
nucleoside triphosphate metabolic process GO:0009141 230 0.079
spindle localization GO:0051653 22 0.078
neuron migration GO:0001764 122 0.078
regulation of cell cycle GO:0051726 281 0.077
ribonucleoside triphosphate catabolic process GO:0009203 199 0.076
organelle localization GO:0051640 179 0.076
meiotic nuclear division GO:0007126 115 0.075
oxidation reduction process GO:0055114 342 0.074
oocyte differentiation GO:0009994 35 0.074
regulation of kinase activity GO:0043549 249 0.073
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.073
signal transduction by p53 class mediator GO:0072331 51 0.072
multicellular organismal aging GO:0010259 24 0.072
protein polyubiquitination GO:0000209 33 0.071
ribonucleoside triphosphate metabolic process GO:0009199 220 0.071
muscle cell differentiation GO:0042692 261 0.069
oocyte anterior posterior axis specification GO:0007314 2 0.069
microtubule based process GO:0007017 236 0.068
Worm Fly
atp catabolic process GO:0006200 55 0.068
regulation of vesicle mediated transport GO:0060627 139 0.068
receptor mediated endocytosis GO:0006898 51 0.068
protein modification by small protein conjugation or removal GO:0070647 207 0.068
purine nucleoside triphosphate metabolic process GO:0009144 226 0.067
regulation of epithelial cell proliferation GO:0050678 141 0.067
positive regulation of intracellular transport GO:0032388 70 0.067
inter male aggressive behavior GO:0002121 3 0.067
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.067
purine ribonucleotide catabolic process GO:0009154 208 0.066
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.066
cerebral cortex development GO:0021987 86 0.066
purine nucleoside triphosphate catabolic process GO:0009146 203 0.065
regulation of secretion GO:0051046 274 0.064
circadian rhythm GO:0007623 114 0.064
epidermal cell division GO:0010481 3 0.064
regulation of exit from mitosis GO:0007096 1 0.064
amine metabolic process GO:0009308 45 0.062
transmembrane transport GO:0055085 412 0.062
Rat
locomotory behavior GO:0007626 195 0.062
epithelial cell proliferation GO:0050673 174 0.062
purine containing compound metabolic process GO:0072521 311 0.062
trna wobble base modification GO:0002097 2 0.061
establishment of spindle localization GO:0051293 19 0.061
ribonucleotide catabolic process GO:0009261 208 0.060
canonical wnt signaling pathway GO:0060070 130 0.060
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.060
negative regulation of phosphorylation GO:0042326 166 0.059
Rat
modification dependent protein catabolic process GO:0019941 133 0.059
negative regulation of synaptic vesicle transport GO:1902804 3 0.058
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.058
regulation of proteolysis GO:0030162 164 0.058
Rat
nucleoside monophosphate metabolic process GO:0009123 85 0.058
regulation of ion transport GO:0043269 215 0.058
Rat
regulation of neuron differentiation GO:0045664 281 0.057
signal transduction in absence of ligand GO:0038034 55 0.056
mrna splicing via spliceosome GO:0000398 43 0.056
regulation of circadian rhythm GO:0042752 58 0.055
melanosome localization GO:0032400 12 0.054
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.054
regulation of cell cycle process GO:0010564 160 0.054
positive regulation of hormone secretion GO:0046887 38 0.053
membrane organization GO:0061024 245 0.052
Worm
rna interference GO:0016246 2 0.052
carbohydrate metabolic process GO:0005975 230 0.052
female gamete generation GO:0007292 74 0.051
Fly
response to peptide GO:1901652 136 0.051
Rat
body morphogenesis GO:0010171 45 0.050
purine nucleotide metabolic process GO:0006163 302 0.050
meiotic cell cycle process GO:1903046 77 0.050
Worm
organophosphate catabolic process GO:0046434 232 0.049
negative regulation of growth GO:0045926 99 0.049
purine nucleoside monophosphate metabolic process GO:0009126 81 0.049
regulation of neurotransmitter levels GO:0001505 87 0.049
developmental maturation GO:0021700 193 0.049
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 13 0.049
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.048
ribonucleoside monophosphate catabolic process GO:0009158 57 0.048
covalent chromatin modification GO:0016569 163 0.048
pallium development GO:0021543 120 0.048
mrna processing GO:0006397 63 0.047
histone modification GO:0016570 159 0.047
energy derivation by oxidation of organic compounds GO:0015980 77 0.047
learning or memory GO:0007611 148 0.047
neurotransmitter transport GO:0006836 76 0.047
establishment of organelle localization GO:0051656 122 0.046
protein localization to organelle GO:0033365 185 0.046
Rat
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 10 0.046
regulation of erk1 and erk2 cascade GO:0070372 71 0.045
negative regulation of cell development GO:0010721 169 0.045
Human Fly
mesenchymal cell differentiation GO:0048762 107 0.045
Human
energy reserve metabolic process GO:0006112 39 0.045
ribosomal small subunit biogenesis GO:0042274 4 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.044
vesicle organization GO:0016050 60 0.044
response to starvation GO:0042594 65 0.044
protein localization to plasma membrane GO:0072659 57 0.044
mesenchymal cell development GO:0014031 93 0.044
Human
negative regulation of intracellular signal transduction GO:1902532 167 0.043
nucleoside phosphate metabolic process GO:0006753 338 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.043
ion transmembrane transport GO:0034220 361 0.043
Rat
establishment of melanosome localization GO:0032401 11 0.043
regulation of cell motility GO:2000145 236 0.043
ribosome biogenesis GO:0042254 20 0.043
mitochondrion organization GO:0007005 134 0.042
glycosyl compound metabolic process GO:1901657 246 0.042
regulation of cellular component biogenesis GO:0044087 181 0.042
cellular amine metabolic process GO:0044106 44 0.042
trna wobble uridine modification GO:0002098 2 0.042
3 utr mediated mrna stabilization GO:0070935 2 0.041
intracellular mrna localization GO:0008298 4 0.041
regulation of cell division GO:0051302 76 0.041
positive regulation of dephosphorylation GO:0035306 6 0.041
Rat
vesicle localization GO:0051648 86 0.040
lipid transport GO:0006869 98 0.040
response to nutrient levels GO:0031667 109 0.040
cellular polysaccharide metabolic process GO:0044264 38 0.039
positive regulation of secretion by cell GO:1903532 114 0.039
regulation of cell migration GO:0030334 219 0.039
regulation of translation GO:0006417 71 0.039
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.039
phagocytosis GO:0006909 66 0.039
Fly
rna localization GO:0006403 23 0.039
muscle tissue development GO:0060537 308 0.039
negative regulation of protein modification process GO:0031400 163 0.039
Rat
glycosyl compound catabolic process GO:1901658 206 0.038
telencephalon development GO:0021537 186 0.038
regulation of protein catabolic process GO:0042176 108 0.038
Rat
nucleoside metabolic process GO:0009116 246 0.037
regulation of lipid transport GO:0032368 36 0.037
regulation of protein serine threonine kinase activity GO:0071900 157 0.037
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.036
positive regulation of growth GO:0045927 104 0.036
cellularization GO:0007349 1 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
regulation of hormone levels GO:0010817 211 0.036
protein targeting GO:0006605 143 0.036
Rat
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.035
regulation of protein localization GO:0032880 231 0.035
Rat
early endosome to late endosome transport GO:0045022 2 0.035
forebrain development GO:0030900 302 0.034
regulation of ras protein signal transduction GO:0046578 114 0.034
lipid biosynthetic process GO:0008610 179 0.034
cellular response to hormone stimulus GO:0032870 150 0.034
Rat
adult behavior GO:0030534 135 0.034
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.034
cell adhesion GO:0007155 329 0.033
Fly
regulation of protein transport GO:0051223 163 0.033
Rat
hormone secretion GO:0046879 128 0.033
regulation of mrna processing GO:0050684 41 0.033
nitrogen compound transport GO:0071705 271 0.033
positive regulation of ion transport GO:0043270 65 0.033
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.033
wnt signaling pathway GO:0016055 188 0.033
Fly
protein polymerization GO:0051258 57 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.032
Human
segmentation GO:0035282 93 0.032
response to extracellular stimulus GO:0009991 127 0.032
cell fate commitment GO:0045165 210 0.032
Fly
positive regulation of insulin secretion GO:0032024 26 0.032
organonitrogen compound catabolic process GO:1901565 264 0.031
aromatic compound catabolic process GO:0019439 286 0.031
regulation of mitosis GO:0007088 29 0.031
atp metabolic process GO:0046034 75 0.031
carbohydrate homeostasis GO:0033500 128 0.031
Rat
negative regulation of ligase activity GO:0051352 3 0.031
positive regulation of secretion GO:0051047 130 0.031
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.031
Human
response to peptide hormone GO:0043434 127 0.031
Rat
cellular protein complex assembly GO:0043623 116 0.031
positive regulation of cellular protein catabolic process GO:1903364 34 0.031
purine nucleotide catabolic process GO:0006195 211 0.030
tissue migration GO:0090130 68 0.030
regulation of ubiquitin protein transferase activity GO:0051438 7 0.030
response to lipopolysaccharide GO:0032496 128 0.030
glucose import GO:0046323 32 0.030
ribonucleoside monophosphate metabolic process GO:0009161 80 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
regulation of establishment of protein localization GO:0070201 181 0.029
Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.028
polysaccharide metabolic process GO:0005976 39 0.028
cation transport GO:0006812 399 0.028
Rat
response to organonitrogen compound GO:0010243 246 0.028
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
positive regulation of cellular component biogenesis GO:0044089 94 0.028
determination of adult lifespan GO:0008340 11 0.028
regulation of nuclear division GO:0051783 56 0.028
regulation of keratinocyte proliferation GO:0010837 15 0.027
regulation of lipid metabolic process GO:0019216 118 0.027
protein localization to nucleus GO:0034504 121 0.027
Rat
cellular glucan metabolic process GO:0006073 32 0.027
positive regulation of protein export from nucleus GO:0046827 4 0.027
neural precursor cell proliferation GO:0061351 121 0.026
Fly
positive regulation of proteolysis GO:0045862 85 0.026
Rat
regulation of cytoplasmic transport GO:1903649 112 0.026
Rat
cellular ketone metabolic process GO:0042180 84 0.026
camera type eye development GO:0043010 266 0.025
i kappab kinase nf kappab signaling GO:0007249 85 0.025
regulation of exocytosis GO:0017157 61 0.025
negative regulation of cell cycle GO:0045786 123 0.025
meiotic chromosome segregation GO:0045132 19 0.025
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.025
peptidyl amino acid modification GO:0018193 336 0.025
neuron projection guidance GO:0097485 141 0.025
protein autophosphorylation GO:0046777 61 0.025
Rat
inflammatory response GO:0006954 244 0.025
mrna metabolic process GO:0016071 84 0.025
peptidyl serine phosphorylation GO:0018105 74 0.024
sensory perception GO:0007600 245 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.024
negative regulation of keratinocyte proliferation GO:0010839 7 0.024
regulation of mitotic cell cycle GO:0007346 126 0.024
fatty acid metabolic process GO:0006631 121 0.024
learning GO:0007612 98 0.024
regulation of stem cell differentiation GO:2000736 50 0.024
Human
actin polymerization or depolymerization GO:0008154 54 0.024
molting cycle GO:0042303 90 0.023
Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
generation of precursor metabolites and energy GO:0006091 103 0.023
zygote asymmetric cell division GO:0010070 2 0.023
muscle adaptation GO:0043500 39 0.023
rap protein signal transduction GO:0032486 3 0.023
regulation of peptide transport GO:0090087 91 0.023
synapse assembly GO:0007416 56 0.023
dna recombination GO:0006310 92 0.023
lymphocyte proliferation GO:0046651 164 0.023
negative regulation of mitotic cell cycle GO:0045930 58 0.023
establishment of protein localization to organelle GO:0072594 118 0.023
Rat
organelle assembly GO:0070925 177 0.023
Fly
regulation of wnt signaling pathway GO:0030111 123 0.023
cellular carbohydrate metabolic process GO:0044262 119 0.023
negative regulation of transferase activity GO:0051348 85 0.023
response to growth factor GO:0070848 198 0.022
positive regulation of nervous system development GO:0051962 221 0.022
nucleotide biosynthetic process GO:0009165 78 0.022
mitotic cell cycle embryonic GO:0045448 5 0.022
microtubule organizing center organization GO:0031023 28 0.022
Worm Fly
ribonucleoprotein complex subunit organization GO:0071826 28 0.022
nucleobase containing compound transport GO:0015931 27 0.022
anatomical structure homeostasis GO:0060249 145 0.022
negative regulation of nervous system development GO:0051961 156 0.021
Fly
regulation of cell projection organization GO:0031344 206 0.021
negative regulation of cell motility GO:2000146 61 0.021
tripartite regional subdivision GO:0007351 9 0.021
water homeostasis GO:0030104 27 0.021
stress activated mapk cascade GO:0051403 80 0.021
cell fate specification GO:0001708 72 0.021
positive regulation of protein complex assembly GO:0031334 45 0.021
double strand break repair GO:0006302 48 0.021
regulation of proteasomal protein catabolic process GO:0061136 46 0.021
negative regulation of intracellular transport GO:0032387 38 0.021
Rat
ribonucleoprotein complex disassembly GO:0032988 3 0.021
regulation of mrna metabolic process GO:1903311 43 0.020
copii coated vesicle budding GO:0090114 2 0.020
positive regulation of epidermis development GO:0045684 13 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.020
cellular response to monosaccharide stimulus GO:0071326 47 0.020
Rat
lipid localization GO:0010876 126 0.020
positive regulation of cell migration GO:0030335 109 0.020
tissue homeostasis GO:0001894 115 0.020
intracellular receptor signaling pathway GO:0030522 74 0.020
regulation of cellular component size GO:0032535 121 0.020
skeletal muscle organ development GO:0060538 163 0.020
organophosphate biosynthetic process GO:0090407 122 0.019
cellular lipid metabolic process GO:0044255 323 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
establishment of rna localization GO:0051236 18 0.019
circadian regulation of gene expression GO:0032922 48 0.019
positive regulation of protein catabolic process GO:0045732 60 0.019
establishment of mitotic spindle localization GO:0040001 12 0.019
endoplasmic reticulum organization GO:0007029 10 0.019
regulation of intracellular protein transport GO:0033157 82 0.019
Rat
regulation of endocytosis GO:0030100 69 0.019
negative regulation of rna splicing GO:0033119 12 0.019
regulation of embryonic development GO:0045995 71 0.019
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.019
positive regulation of cell growth GO:0030307 33 0.019
positive regulation of smooth muscle cell migration GO:0014911 4 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
protein processing GO:0016485 163 0.019
smoothened signaling pathway GO:0007224 105 0.018
Fly
immune response in mucosal associated lymphoid tissue GO:0002386 2 0.018
negative regulation of response to wounding GO:1903035 77 0.018
keratinocyte differentiation GO:0030216 48 0.018
dna packaging GO:0006323 30 0.018
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.018
purine nucleoside monophosphate catabolic process GO:0009128 58 0.018
establishment of pigment granule localization GO:0051905 12 0.018
negative regulation of wnt signaling pathway GO:0030178 73 0.018
regulation of nucleocytoplasmic transport GO:0046822 73 0.018
Rat
nuclear import GO:0051170 95 0.018
Rat
positive regulation of defense response GO:0031349 124 0.018
regulation of microtubule based process GO:0032886 52 0.018
striated muscle tissue development GO:0014706 293 0.018
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.017
rna splicing via transesterification reactions GO:0000375 43 0.017
positive regulation of cytoplasmic transport GO:1903651 40 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
reproductive behavior GO:0019098 32 0.017
digestive system development GO:0055123 200 0.017
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.017
cell cycle g1 s phase transition GO:0044843 57 0.017
nuclear dna replication GO:0033260 3 0.017
cation transmembrane transport GO:0098655 266 0.017
Rat
regulation of hormone secretion GO:0046883 88 0.017
cellular response to hexose stimulus GO:0071331 47 0.017
Rat
positive regulation of epidermal cell differentiation GO:0045606 6 0.017
positive regulation of cell development GO:0010720 237 0.017
posttranscriptional gene silencing GO:0016441 10 0.017
protein stabilization GO:0050821 25 0.016
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.016
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.016
nucleus localization GO:0051647 20 0.016
negative regulation of gene expression epigenetic GO:0045814 15 0.016
positive regulation of cell cycle GO:0045787 92 0.016
leukocyte proliferation GO:0070661 172 0.016
establishment of vesicle localization GO:0051650 81 0.016
divalent inorganic cation transport GO:0072511 178 0.016
Rat
single organism cell adhesion GO:0098602 156 0.016
negative regulation of protein ubiquitination GO:0031397 19 0.016
glucan metabolic process GO:0044042 32 0.016
negative regulation of cell growth GO:0030308 44 0.016
mitochondrion distribution GO:0048311 4 0.016
regulation of stress activated mapk cascade GO:0032872 69 0.016
mitotic cytokinesis GO:0000281 4 0.016
axon guidance GO:0007411 141 0.016
positive regulation of protein modification process GO:0031401 299 0.015
Human Rat
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.015
compound eye development GO:0048749 1 0.015
Fly
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
protein targeting to vacuole GO:0006623 3 0.015
immune effector process GO:0002252 321 0.015
regulation of epidermis development GO:0045682 33 0.015
positive regulation of translation GO:0045727 19 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
Human
multicellular organism growth GO:0035264 161 0.015
regulation of protein binding GO:0043393 60 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.015
negative regulation of protein processing GO:0010955 79 0.015
negative regulation of pathway restricted smad protein phosphorylation GO:0060394 1 0.015
regulation of transmembrane transport GO:0034762 128 0.015
Rat
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.015
trna processing GO:0008033 11 0.015
transcription from rna polymerase i promoter GO:0006360 13 0.015

Ppp2ca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
musculoskeletal system disease DOID:17 0 0.034
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
muscular dystrophy DOID:9884 0 0.024
muscle tissue disease DOID:66 0 0.024