Mus musculus

54 known processes

Ppp2cb

protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform

(Aliases: D8Ertd766e,PP2Ac,AI115466)

Ppp2cb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein ubiquitination GO:0016567 171 0.070
nucleoside phosphate metabolic process GO:0006753 338 0.069
amine metabolic process GO:0009308 45 0.061
mapk cascade GO:0000165 281 0.061
purine containing compound metabolic process GO:0072521 311 0.060
intracellular protein transport GO:0006886 204 0.059
nucleotide metabolic process GO:0009117 332 0.059
purine nucleotide metabolic process GO:0006163 302 0.057
protein modification by small protein conjugation GO:0032446 187 0.055
protein modification by small protein conjugation or removal GO:0070647 207 0.055
aromatic compound catabolic process GO:0019439 286 0.051
heterocycle catabolic process GO:0046700 280 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
ribonucleoside triphosphate catabolic process GO:0009203 199 0.045
membrane organization GO:0061024 245 0.044
ribonucleoside metabolic process GO:0009119 245 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.041
cytoplasmic transport GO:0016482 234 0.041
endomembrane system organization GO:0010256 147 0.041
protein catabolic process GO:0030163 221 0.039
nucleoside phosphate catabolic process GO:1901292 222 0.039
organic cyclic compound catabolic process GO:1901361 295 0.038
organophosphate catabolic process GO:0046434 232 0.037
purine nucleoside catabolic process GO:0006152 205 0.036
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.035
regulation of mapk cascade GO:0043408 248 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
purine ribonucleoside catabolic process GO:0046130 205 0.034
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
cation transmembrane transport GO:0098655 266 0.034
cell adhesion GO:0007155 329 0.033
Fly
negative regulation of protein metabolic process GO:0051248 282 0.033
cellular ketone metabolic process GO:0042180 84 0.033
macromolecule methylation GO:0043414 120 0.032
regulation of apoptotic signaling pathway GO:2001233 197 0.032
apoptotic signaling pathway GO:0097190 306 0.032
ras protein signal transduction GO:0007265 77 0.032
Rat
regulation of cellular amine metabolic process GO:0033238 20 0.031
ion transmembrane transport GO:0034220 361 0.031
purine nucleoside triphosphate catabolic process GO:0009146 203 0.031
regulation of organelle organization GO:0033043 289 0.031
purine nucleotide catabolic process GO:0006195 211 0.030
cellular response to dna damage stimulus GO:0006974 207 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
dephosphorylation GO:0016311 129 0.029
Rat Fly
positive regulation of protein modification process GO:0031401 299 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
regulation of cell activation GO:0050865 289 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.028
covalent chromatin modification GO:0016569 163 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
negative regulation of protein modification process GO:0031400 163 0.026
nucleoside metabolic process GO:0009116 246 0.026
modification dependent macromolecule catabolic process GO:0043632 133 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.026
cellular amino acid metabolic process GO:0006520 103 0.026
response to organonitrogen compound GO:0010243 246 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
Rat
transmembrane transport GO:0055085 412 0.025
regulation of purine nucleotide catabolic process GO:0033121 122 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
nucleotide catabolic process GO:0009166 217 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
regulation of ras protein signal transduction GO:0046578 114 0.024
Rat
macromolecule catabolic process GO:0009057 281 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
negative regulation of cell cycle GO:0045786 123 0.024
muscle system process GO:0003012 141 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
cellular protein catabolic process GO:0044257 155 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
guanosine containing compound catabolic process GO:1901069 144 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
cellular amine metabolic process GO:0044106 44 0.023
regulation of cell cycle GO:0051726 281 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
cation transport GO:0006812 399 0.022
purine containing compound catabolic process GO:0072523 213 0.022
negative regulation of phosphorylation GO:0042326 166 0.022
nuclear division GO:0000280 158 0.022
Fly
nucleoside catabolic process GO:0009164 206 0.022
oocyte construction GO:0007308 2 0.022
sensory perception GO:0007600 245 0.022
pole plasm assembly GO:0007315 2 0.021
cell division GO:0051301 120 0.021
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
regulation of protein localization GO:0032880 231 0.021
oocyte axis specification GO:0007309 2 0.021
regulation of cytokine production GO:0001817 266 0.021
heart morphogenesis GO:0003007 178 0.021
positive regulation of cell death GO:0010942 224 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
Fly
regulation of homeostatic process GO:0032844 182 0.020
nitrogen compound transport GO:0071705 271 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
mitotic cell cycle process GO:1903047 159 0.020
Fly
positive regulation of cell activation GO:0050867 158 0.019
regulation of intracellular transport GO:0032386 159 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
organelle assembly GO:0070925 177 0.019
Fly
organelle localization GO:0051640 179 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
glycoprotein biosynthetic process GO:0009101 89 0.018
t cell activation GO:0042110 289 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
regulation of cell cycle process GO:0010564 160 0.018
lateral inhibition GO:0046331 1 0.018
regulation of hydrolase activity GO:0051336 246 0.018
regulation of transferase activity GO:0051338 263 0.018
regulation of secretion GO:0051046 274 0.018
organelle fission GO:0048285 170 0.018
Fly
guanosine containing compound metabolic process GO:1901068 144 0.018
asymmetric neuroblast division GO:0055059 1 0.018
Fly
positive regulation of organelle organization GO:0010638 128 0.018
cell fate commitment GO:0045165 210 0.018
Fly
stress activated mapk cascade GO:0051403 80 0.018
homeostasis of number of cells GO:0048872 210 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.017
single organism cell adhesion GO:0098602 156 0.017
glycoprotein metabolic process GO:0009100 116 0.017
circulatory system process GO:0003013 197 0.017
response to radiation GO:0009314 165 0.017
Fly
positive regulation of lymphocyte activation GO:0051251 140 0.017
divalent metal ion transport GO:0070838 172 0.017
rho protein signal transduction GO:0007266 32 0.017
peptidyl amino acid modification GO:0018193 336 0.017
regulation of kinase activity GO:0043549 249 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
retrograde transport endosome to golgi GO:0042147 2 0.017
regulation of cellular response to stress GO:0080135 159 0.017
neuron death GO:0070997 154 0.017
protein localization to organelle GO:0033365 185 0.017
negative regulation of molecular function GO:0044092 258 0.017
regulation of t cell activation GO:0050863 170 0.017
regulation of cellular component size GO:0032535 121 0.017
jnk cascade GO:0007254 72 0.017
gtp metabolic process GO:0046039 144 0.017
myeloid cell differentiation GO:0030099 233 0.017
fat cell differentiation GO:0045444 160 0.017
response to lipopolysaccharide GO:0032496 128 0.016
response to growth factor GO:0070848 198 0.016
meiotic cell cycle process GO:1903046 77 0.016
cellular chemical homeostasis GO:0055082 215 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
regulation of map kinase activity GO:0043405 120 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
regulation of cell motility GO:2000145 236 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
actin filament organization GO:0007015 113 0.016
Fly
neural tube development GO:0021915 160 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
regionalization GO:0003002 337 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
localization within membrane GO:0051668 4 0.016
microtubule based process GO:0007017 236 0.016
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
stem cell development GO:0048864 219 0.016
digestive tract morphogenesis GO:0048546 147 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
negative regulation of nervous system development GO:0051961 156 0.015
Fly
vesicle organization GO:0016050 60 0.015
regulation of ion transport GO:0043269 215 0.015
gtp catabolic process GO:0006184 143 0.015
learning or memory GO:0007611 148 0.015
synaptic transmission GO:0007268 329 0.015
muscle cell differentiation GO:0042692 261 0.015
response to acid chemical GO:0001101 111 0.015
positive regulation of transferase activity GO:0051347 167 0.015
mitotic cell cycle GO:0000278 195 0.015
Fly
cellular macromolecule catabolic process GO:0044265 206 0.015
cellular lipid metabolic process GO:0044255 323 0.015
cognition GO:0050890 149 0.015
telencephalon development GO:0021537 186 0.015
immune effector process GO:0002252 321 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
regulation of gtp catabolic process GO:0033124 113 0.014
regulation of secretion by cell GO:1903530 249 0.014
regulation of proteolysis GO:0030162 164 0.014
neural precursor cell proliferation GO:0061351 121 0.014
Fly
positive regulation of programmed cell death GO:0043068 218 0.014
regulation of clathrin mediated endocytosis GO:2000369 4 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
multicellular organism growth GO:0035264 161 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
negative regulation of cell development GO:0010721 169 0.014
Fly
methylation GO:0032259 134 0.014
fertilization GO:0009566 127 0.014
regulation of protein catabolic process GO:0042176 108 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
regulation of protein kinase activity GO:0045859 232 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
compound eye development GO:0048749 1 0.014
Fly
positive regulation of secretion by cell GO:1903532 114 0.014
leukocyte proliferation GO:0070661 172 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
protein complex disassembly GO:0043241 40 0.014
synapse organization GO:0050808 125 0.014
anion transport GO:0006820 177 0.014
dna metabolic process GO:0006259 303 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
regulation of cell projection organization GO:0031344 206 0.014
autophagy GO:0006914 45 0.014
Fly
reactive oxygen species metabolic process GO:0072593 84 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
asymmetric stem cell division GO:0098722 3 0.014
Fly
digestive system development GO:0055123 200 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
Rat
spermatogenesis GO:0007283 284 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
skeletal system development GO:0001501 356 0.013
regulation of response to wounding GO:1903034 189 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
maintenance of location GO:0051235 89 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
axonogenesis GO:0007409 274 0.013
learning GO:0007612 98 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
multicellular organismal signaling GO:0035637 91 0.013
lamellipodium organization GO:0097581 29 0.013
camera type eye development GO:0043010 266 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of neuron differentiation GO:0045664 281 0.013
positive regulation of cell development GO:0010720 237 0.013
chromatin organization GO:0006325 206 0.013
striated muscle cell development GO:0055002 125 0.013
regulation of inflammatory response GO:0050727 147 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
centrosome separation GO:0051299 4 0.013
forebrain development GO:0030900 302 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
cytokine production GO:0001816 319 0.013
transmission of nerve impulse GO:0019226 76 0.013
multi organism behavior GO:0051705 62 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
regulation of anatomical structure size GO:0090066 178 0.013
leukocyte mediated immunity GO:0002443 174 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
divalent inorganic cation transport GO:0072511 178 0.013
endocytosis GO:0006897 168 0.012
Fly
negative regulation of cell proliferation GO:0008285 296 0.012
Fly
inflammatory response GO:0006954 244 0.012
mrna splicing via spliceosome GO:0000398 43 0.012
male gamete generation GO:0048232 285 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
regulation of membrane potential GO:0042391 192 0.012
protein processing GO:0016485 163 0.012
calcium ion transport GO:0006816 159 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
lymphocyte proliferation GO:0046651 164 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
anatomical structure homeostasis GO:0060249 145 0.012
leukocyte differentiation GO:0002521 342 0.012
locomotory behavior GO:0007626 195 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
muscle tissue development GO:0060537 308 0.012
synaptic vesicle localization GO:0097479 59 0.012
chemotaxis GO:0006935 247 0.012
ameboidal type cell migration GO:0001667 128 0.012
stem cell differentiation GO:0048863 268 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
meiotic cell cycle GO:0051321 122 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
positive regulation of nervous system development GO:0051962 221 0.012
action potential GO:0001508 78 0.012
protein secretion GO:0009306 111 0.012
cellular protein complex assembly GO:0043623 116 0.012
cyclic nucleotide metabolic process GO:0009187 59 0.012
visual perception GO:0007601 52 0.012
response to light stimulus GO:0009416 135 0.012
Fly
epithelial tube morphogenesis GO:0060562 303 0.012
sequestering of metal ion GO:0051238 19 0.012
dna recombination GO:0006310 92 0.012
digestive tract development GO:0048565 190 0.012
protein targeting GO:0006605 143 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
leukocyte migration GO:0050900 124 0.011
negative regulation of immune system process GO:0002683 209 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
regulation of protein transport GO:0051223 163 0.011
muscle contraction GO:0006936 101 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
regulation of cell migration GO:0030334 219 0.011
regulation of adaptive immune response GO:0002819 90 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
protein alkylation GO:0008213 81 0.011
developmental maturation GO:0021700 193 0.011
respiratory system development GO:0060541 190 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
response to nutrient levels GO:0031667 109 0.011
neural tube formation GO:0001841 108 0.011
primary neural tube formation GO:0014020 95 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
positive regulation of kinase activity GO:0033674 155 0.011
positive regulation of cell motility GO:2000147 116 0.011
positive regulation of secretion GO:0051047 130 0.011
negative regulation of organelle organization GO:0010639 90 0.011
regulation of protein complex assembly GO:0043254 83 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
positive regulation of t cell activation GO:0050870 101 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
positive regulation of immune effector process GO:0002699 107 0.010
skeletal muscle organ development GO:0060538 163 0.010
rna splicing GO:0008380 54 0.010
mrna metabolic process GO:0016071 84 0.010
actin filament polymerization GO:0030041 44 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
negative regulation of synapse assembly GO:0051964 3 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
regulation of system process GO:0044057 200 0.010
striated muscle tissue development GO:0014706 293 0.010
regulation of mrna processing GO:0050684 41 0.010
regulation of cell adhesion GO:0030155 154 0.010
heart process GO:0003015 94 0.010
germ cell development GO:0007281 185 0.010
Fly
cellular response to lipid GO:0071396 145 0.010
protein localization to nucleus GO:0034504 121 0.010
cellular homeostasis GO:0019725 240 0.010
calcium ion transmembrane transport GO:0070588 85 0.010
regulation of neuron projection development GO:0010975 169 0.010
cation homeostasis GO:0055080 212 0.010

Ppp2cb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.021
organ system cancer DOID:0050686 0 0.021
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.014