Mus musculus

0 known processes

Igl

immunoglobulin lambda chain complex

(Aliases: Igl-x,MGC6743)

Igl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein methylation GO:0006479 81 0.330
vestibular receptor cell development GO:0060118 2 0.295
methylation GO:0032259 134 0.209
regulation of b cell mediated immunity GO:0002712 37 0.169
leukocyte differentiation GO:0002521 342 0.164
negative regulation of stem cell maintenance GO:1902455 4 0.160
histone lysine methylation GO:0034968 50 0.151
cellular response to monosaccharide stimulus GO:0071326 47 0.140
macromolecule methylation GO:0043414 120 0.137
adaptive immune response GO:0002250 155 0.127
vestibular reflex GO:0060005 4 0.124
cellular response to acid chemical GO:0071229 68 0.115
response to acid chemical GO:0001101 111 0.111
regulation of cellular ketone metabolic process GO:0010565 66 0.107
lymphocyte mediated immunity GO:0002449 139 0.107
retinal cone cell differentiation GO:0042670 8 0.106
protein alkylation GO:0008213 81 0.105
inner ear receptor cell development GO:0060119 39 0.103
regulation of chromatin modification GO:1903308 57 0.100
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.096
cellular response to hexose stimulus GO:0071331 47 0.090
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.090
covalent chromatin modification GO:0016569 163 0.090
negative regulation of protein modification process GO:0031400 163 0.088
eye photoreceptor cell differentiation GO:0001754 41 0.087
positive regulation of metanephric glomerulus development GO:0072300 4 0.085
retina development in camera type eye GO:0060041 119 0.085
positive regulation of adaptive immune response GO:0002821 61 0.085
lymphocyte differentiation GO:0030098 242 0.082
negative regulation of protein metabolic process GO:0051248 282 0.082
response to monosaccharide GO:0034284 67 0.080
neural tube closure GO:0001843 90 0.078
regulation of leukocyte mediated immunity GO:0002703 104 0.078
stem cell maintenance GO:0019827 130 0.076
chromatin organization GO:0006325 206 0.074
cellular response to lipid GO:0071396 145 0.071
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.071
regulation of hormone levels GO:0010817 211 0.071
anatomical structure maturation GO:0071695 49 0.070
regulation of cellular amino acid metabolic process GO:0006521 5 0.070
histone methylation GO:0016571 71 0.070
camera type eye development GO:0043010 266 0.068
primary neural tube formation GO:0014020 95 0.066
cellular modified amino acid metabolic process GO:0006575 63 0.066
histone modification GO:0016570 159 0.065
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.063
b cell mediated immunity GO:0019724 71 0.063
regulation of neuron differentiation GO:0045664 281 0.063
immune effector process GO:0002252 321 0.061
negative regulation of histone methylation GO:0031061 10 0.061
cellular ketone metabolic process GO:0042180 84 0.060
cellular amine metabolic process GO:0044106 44 0.058
regulation of histone modification GO:0031056 56 0.058
chromatin modification GO:0016568 187 0.058
oxidation reduction process GO:0055114 342 0.057
positive regulation of leukocyte mediated immunity GO:0002705 70 0.057
regulation of lymphocyte mediated immunity GO:0002706 84 0.057
nephron tubule development GO:0072080 84 0.054
cellular amino acid metabolic process GO:0006520 103 0.053
positive regulation of type ii hypersensitivity GO:0002894 4 0.053
photoreceptor cell differentiation GO:0046530 52 0.053
positive regulation of b cell mediated immunity GO:0002714 26 0.052
regulation of lymphocyte activation GO:0051249 240 0.052
reactive oxygen species metabolic process GO:0072593 84 0.052
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.049
skin development GO:0043588 220 0.049
regulation of organelle organization GO:0033043 289 0.049
thyroid hormone generation GO:0006590 7 0.048
negative regulation of organelle organization GO:0010639 90 0.047
regulation of histone methylation GO:0031060 30 0.047
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.045
response to inorganic substance GO:0010035 96 0.045
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.045
cellular chemical homeostasis GO:0055082 215 0.045
carbohydrate homeostasis GO:0033500 128 0.045
regulation of chromatin organization GO:1902275 57 0.045
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
regulation of defense response GO:0031347 233 0.044
developmental maturation GO:0021700 193 0.044
anatomical structure arrangement GO:0048532 20 0.043
defense response to other organism GO:0098542 197 0.043
regulation of morphogenesis of a branching structure GO:0060688 53 0.043
hormone metabolic process GO:0042445 86 0.043
sensory organ morphogenesis GO:0090596 242 0.043
regulation of thyroid hormone generation GO:2000609 4 0.043
tube closure GO:0060606 91 0.043
negative regulation of kidney development GO:0090185 15 0.042
kidney epithelium development GO:0072073 121 0.041
phenol containing compound metabolic process GO:0018958 60 0.040
tube formation GO:0035148 140 0.040
complement activation GO:0006956 16 0.040
glucose homeostasis GO:0042593 128 0.039
regulation of inflammatory response GO:0050727 147 0.039
protein kinase b signaling GO:0043491 74 0.038
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.038
regulation of anatomical structure size GO:0090066 178 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
ear development GO:0043583 200 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.036
positive regulation of cell development GO:0010720 237 0.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.035
immunoglobulin mediated immune response GO:0016064 69 0.035
negative regulation of cell development GO:0010721 169 0.034
response to oxidative stress GO:0006979 123 0.034
macromolecule catabolic process GO:0009057 281 0.034
positive regulation of nervous system development GO:0051962 221 0.034
cellular response to external stimulus GO:0071496 88 0.033
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.033
nephron epithelium morphogenesis GO:0072088 68 0.033
humoral immune response GO:0006959 57 0.033
regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900211 4 0.032
negative regulation of molecular function GO:0044092 258 0.032
cell type specific apoptotic process GO:0097285 268 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
neural tube development GO:0021915 160 0.031
positive regulation of inflammatory response GO:0050729 47 0.030
dna metabolic process GO:0006259 303 0.030
cellular response to oxidative stress GO:0034599 76 0.030
cellular glucose homeostasis GO:0001678 52 0.029
morphogenesis of embryonic epithelium GO:0016331 159 0.029
hypersensitivity GO:0002524 10 0.029
cranial nerve formation GO:0021603 4 0.029
response to retinoic acid GO:0032526 56 0.029
regulation of chromosome organization GO:0033044 83 0.029
glomerulus development GO:0032835 40 0.028
retina morphogenesis in camera type eye GO:0060042 45 0.028
neural retina development GO:0003407 41 0.028
cd4 positive alpha beta t cell activation GO:0035710 45 0.028
striated muscle tissue development GO:0014706 293 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.027
protein catabolic process GO:0030163 221 0.027
leukocyte proliferation GO:0070661 172 0.027
negative regulation of chromosome organization GO:2001251 30 0.027
renal tubule development GO:0061326 87 0.027
positive regulation of immune effector process GO:0002699 107 0.026
cellular homeostasis GO:0019725 240 0.026
cellular response to biotic stimulus GO:0071216 92 0.026
b cell differentiation GO:0030183 78 0.026
skeletal system development GO:0001501 356 0.026
nerve development GO:0021675 67 0.026
nephron tubule morphogenesis GO:0072078 68 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
positive regulation of hormone metabolic process GO:0032352 3 0.026
stem cell differentiation GO:0048863 268 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.025
epithelial tube formation GO:0072175 130 0.025
positive regulation of phagocytosis GO:0050766 26 0.025
t cell activation GO:0042110 289 0.024
hair cell differentiation GO:0035315 40 0.024
response to hydrogen peroxide GO:0042542 32 0.024
endoderm development GO:0007492 45 0.024
urogenital system development GO:0001655 261 0.023
regulation of t cell activation GO:0050863 170 0.023
nephron development GO:0072006 109 0.023
regulation of metanephros development GO:0072215 15 0.023
ureter morphogenesis GO:0072197 4 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
epithelial cell development GO:0002064 159 0.022
vestibulocochlear nerve morphogenesis GO:0021648 4 0.022
optic nerve structural organization GO:0021633 2 0.022
developmental programmed cell death GO:0010623 41 0.022
mesonephric tubule development GO:0072164 94 0.022
protein activation cascade GO:0072376 19 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
skeletal muscle organ development GO:0060538 163 0.021
dendrite development GO:0016358 115 0.021
lymphocyte apoptotic process GO:0070227 54 0.020
muscle tissue development GO:0060537 308 0.020
thymus development GO:0048538 41 0.020
nephron epithelium development GO:0072009 92 0.020
regulation of protein maturation GO:1903317 96 0.020
regulation of stem cell maintenance GO:2000036 17 0.020
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.020
kidney morphogenesis GO:0060993 83 0.020
regulation of kidney size GO:0035564 3 0.020
mesenchymal cell apoptotic process involved in metanephros development GO:1900200 4 0.020
skeletal system morphogenesis GO:0048705 203 0.020
inner ear morphogenesis GO:0042472 101 0.020
response to reactive oxygen species GO:0000302 56 0.019
positive regulation of thyroid hormone generation GO:2000611 2 0.019
negative regulation of hydrolase activity GO:0051346 71 0.019
lipid transport GO:0006869 98 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
response to amino acid GO:0043200 37 0.019
organ maturation GO:0048799 17 0.019
stem cell development GO:0048864 219 0.019
regulation of phagocytosis GO:0050764 33 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
brain morphogenesis GO:0048854 32 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
camera type eye photoreceptor cell differentiation GO:0060219 15 0.018
homeostasis of number of cells GO:0048872 210 0.018
negative regulation of chromatin modification GO:1903309 19 0.018
regulation of response to wounding GO:1903034 189 0.018
lymphocyte homeostasis GO:0002260 64 0.018
thyroid hormone metabolic process GO:0042403 16 0.018
regionalization GO:0003002 337 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
cell adhesion GO:0007155 329 0.018
dephosphorylation GO:0016311 129 0.018
alpha beta t cell differentiation GO:0046632 69 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
ear morphogenesis GO:0042471 118 0.017
gland development GO:0048732 330 0.017
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.017
leukocyte homeostasis GO:0001776 79 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
regulation of histone h3 k9 methylation GO:0051570 8 0.017
photoreceptor cell fate commitment GO:0046552 2 0.017
regulation of protein processing GO:0070613 96 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
mesonephric epithelium development GO:0072163 94 0.017
regulation of metanephric glomerulus development GO:0072298 5 0.017
renal system pattern specification GO:0072048 9 0.017
regulation of secretion GO:0051046 274 0.016
protein maturation GO:0051604 176 0.016
regulation of leukocyte apoptotic process GO:2000106 56 0.016
regulation of hydrolase activity GO:0051336 246 0.016
mesonephric tubule morphogenesis GO:0072171 63 0.016
positive regulation of kinase activity GO:0033674 155 0.016
epithelial cell differentiation involved in kidney development GO:0035850 23 0.016
cellular response to amino acid stimulus GO:0071230 29 0.016
bone morphogenesis GO:0060349 78 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
immature b cell differentiation GO:0002327 10 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
mesenchyme development GO:0060485 152 0.015
peptide hormone secretion GO:0030072 109 0.015
cell recognition GO:0008037 83 0.015
digestive tract development GO:0048565 190 0.015
b cell activation GO:0042113 161 0.015
alpha beta t cell activation GO:0046631 91 0.015
negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 4 0.015
cellular response to abiotic stimulus GO:0071214 56 0.015
negative regulation of protein processing GO:0010955 79 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
reflex GO:0060004 22 0.015
leukocyte mediated cytotoxicity GO:0001909 62 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
regulation of type iia hypersensitivity GO:0001796 4 0.014
skeletal muscle cell differentiation GO:0035914 66 0.014
nephric duct formation GO:0072179 4 0.014
regulation of glomerulus development GO:0090192 6 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
negative regulation of lymphocyte activation GO:0051250 91 0.014
vestibulocochlear nerve formation GO:0021650 2 0.014
mesoderm development GO:0007498 100 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
intracellular protein transport GO:0006886 204 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
renal system development GO:0072001 225 0.014
somitogenesis GO:0001756 69 0.014
multicellular organism growth GO:0035264 161 0.014
organ growth GO:0035265 117 0.014
mesonephros development GO:0001823 97 0.013
paramesonephric duct development GO:0061205 3 0.013
mechanoreceptor differentiation GO:0042490 67 0.013
kidney development GO:0001822 213 0.013
regulation of neural retina development GO:0061074 3 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
ureteric bud morphogenesis GO:0060675 62 0.013
histone h3 k9 methylation GO:0051567 17 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
pancreas development GO:0031016 57 0.013
sclerotome development GO:0061056 4 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
immunoglobulin production GO:0002377 73 0.013
regulation of photoreceptor cell differentiation GO:0046532 4 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
ras protein signal transduction GO:0007265 77 0.013
leukocyte activation involved in immune response GO:0002366 126 0.012
gastrulation GO:0007369 116 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
positive regulation of glomerulus development GO:0090193 5 0.012
regulation of secretion by cell GO:1903530 249 0.012
regulation of type i hypersensitivity GO:0001810 4 0.012
positive regulation of metanephros development GO:0072216 9 0.012
regulation of metal ion transport GO:0010959 106 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
mapk cascade GO:0000165 281 0.012
regulation of multi organism process GO:0043900 111 0.012
face morphogenesis GO:0060325 29 0.012
regulation of peptidase activity GO:0052547 96 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
membrane organization GO:0061024 245 0.012
bone development GO:0060348 120 0.012
aromatic compound catabolic process GO:0019439 286 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
regulation of stem cell differentiation GO:2000736 50 0.012
glial cell differentiation GO:0010001 131 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
segmentation GO:0035282 93 0.012
negative regulation of cell activation GO:0050866 111 0.012
negative regulation of protein maturation GO:1903318 79 0.012
regulation of t cell proliferation GO:0042129 92 0.012
hair cycle GO:0042633 90 0.012
inner ear receptor cell differentiation GO:0060113 61 0.012
regulation of establishment of protein localization GO:0070201 181 0.011
t cell proliferation GO:0042098 120 0.011
amine metabolic process GO:0009308 45 0.011
carbohydrate metabolic process GO:0005975 230 0.011
response to organonitrogen compound GO:0010243 246 0.011
cranial nerve morphogenesis GO:0021602 26 0.011
digestive system development GO:0055123 200 0.011
cell fate commitment GO:0045165 210 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
ureteric bud development GO:0001657 94 0.011
cell killing GO:0001906 67 0.011
renal vesicle development GO:0072087 17 0.011
response to growth factor GO:0070848 198 0.011
nucleoside catabolic process GO:0009164 206 0.011
positive regulation of protein modification process GO:0031401 299 0.011
nucleotide metabolic process GO:0009117 332 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
mesoderm morphogenesis GO:0048332 64 0.011
negative regulation of metanephros development GO:0072217 6 0.011
monosaccharide metabolic process GO:0005996 106 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
regulation of membrane potential GO:0042391 192 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
mesenchymal cell differentiation GO:0048762 107 0.011
t cell differentiation GO:0030217 174 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
embryonic organ morphogenesis GO:0048562 276 0.010
regulation of metanephros size GO:0035566 2 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.010
interleukin 10 secretion GO:0072608 4 0.010
rho protein signal transduction GO:0007266 32 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
regulation of retina development in camera type eye GO:1902866 3 0.010
cell differentiation involved in metanephros development GO:0072202 12 0.010
optic nerve development GO:0021554 8 0.010
phagocytosis recognition GO:0006910 12 0.010
dna repair GO:0006281 107 0.010
regulation of endocytosis GO:0030100 69 0.010
leukocyte mediated immunity GO:0002443 174 0.010
dct cell differentiation GO:0072069 3 0.010

Igl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.193
disease of cellular proliferation DOID:14566 0 0.193
organ system cancer DOID:0050686 0 0.193
immune system cancer DOID:0060083 0 0.102
hematologic cancer DOID:2531 0 0.102
leukemia DOID:1240 0 0.102
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016