Mus musculus

48 known processes

P2rx4

purinergic receptor P2X, ligand-gated ion channel 4

(Aliases: P2X4,D5Ertd444e,AW555605,AI504491)

P2rx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.182
lymphocyte mediated immunity GO:0002449 139 0.181
Mouse
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.126
Mouse
lytic vacuole organization GO:0080171 21 0.120
Mouse
positive regulation of cytokine production GO:0001819 174 0.104
Mouse
adaptive immune response GO:0002250 155 0.104
Mouse
leukocyte mediated immunity GO:0002443 174 0.100
Mouse
transmembrane transport GO:0055085 412 0.099
cytokine production GO:0001816 319 0.097
Mouse
immune effector process GO:0002252 321 0.090
Mouse
regulation of adaptive immune response GO:0002819 90 0.089
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.078
reactive nitrogen species metabolic process GO:2001057 0 0.077
cation transport GO:0006812 399 0.073
regulation of leukocyte mediated immunity GO:0002703 104 0.069
Mouse
vacuole organization GO:0007033 38 0.067
Mouse
cellular ketone metabolic process GO:0042180 84 0.065
cellular amine metabolic process GO:0044106 44 0.064
t cell mediated immunity GO:0002456 50 0.062
Mouse
sphingolipid metabolic process GO:0006665 45 0.062
Mouse
positive regulation of apoptotic process GO:0043065 217 0.062
Mouse
regulation of peptidase activity GO:0052547 96 0.059
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.059
Mouse
divalent metal ion transport GO:0070838 172 0.057
cation transmembrane transport GO:0098655 266 0.054
regulation of lymphocyte mediated immunity GO:0002706 84 0.053
Mouse
apoptotic signaling pathway GO:0097190 306 0.051
Human Mouse
organonitrogen compound catabolic process GO:1901565 264 0.050
cellular amino acid metabolic process GO:0006520 103 0.049
response to molecule of bacterial origin GO:0002237 143 0.049
Mouse
ceramide biosynthetic process GO:0046513 20 0.048
Mouse
lysosome organization GO:0007040 21 0.048
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.045
positive regulation of apoptotic signaling pathway GO:2001235 95 0.044
metal ion homeostasis GO:0055065 189 0.044
Human Mouse
cation homeostasis GO:0055080 212 0.044
Human Mouse
positive regulation of proteolysis GO:0045862 85 0.044
Mouse
interleukin 1 beta production GO:0032611 30 0.043
Mouse
positive regulation of cell death GO:0010942 224 0.042
Mouse
regulation of membrane potential GO:0042391 192 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.042
protein maturation GO:0051604 176 0.042
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.041
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.040
Mouse
regulation of establishment of protein localization GO:0070201 181 0.039
Mouse
regulation of cellular catabolic process GO:0031329 242 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
cellular lipid metabolic process GO:0044255 323 0.039
Mouse
phospholipid transfer to membrane GO:0006649 2 0.039
Mouse
nitrogen compound transport GO:0071705 271 0.039
Mouse
multicellular organismal homeostasis GO:0048871 164 0.039
Mouse
organophosphate catabolic process GO:0046434 232 0.038
anion transport GO:0006820 177 0.038
Mouse
regulation of t cell mediated immunity GO:0002709 34 0.038
Mouse
amino acid transport GO:0006865 61 0.038
Mouse
t cell activation GO:0042110 289 0.038
Mouse
response to lipopolysaccharide GO:0032496 128 0.037
Mouse
divalent inorganic cation transport GO:0072511 178 0.037
protein processing GO:0016485 163 0.036
Mouse
amine metabolic process GO:0009308 45 0.036
homeostasis of number of cells GO:0048872 210 0.036
Mouse
glycosyl compound catabolic process GO:1901658 206 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
ossification GO:0001503 216 0.034
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.034
calcium ion transport GO:0006816 159 0.033
alpha beta t cell activation GO:0046631 91 0.032
sequestering of metal ion GO:0051238 19 0.031
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.031
inorganic cation transmembrane transport GO:0098662 207 0.031
endocytosis GO:0006897 168 0.031
Mouse
ribonucleoside catabolic process GO:0042454 206 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.030
male gamete generation GO:0048232 285 0.030
oxidation reduction process GO:0055114 342 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
carboxylic acid transport GO:0046942 100 0.029
Mouse
regulation of secretion GO:0051046 274 0.028
Mouse
negative regulation of cell activation GO:0050866 111 0.028
carbohydrate metabolic process GO:0005975 230 0.028
cell killing GO:0001906 67 0.028
Mouse
skeletal system development GO:0001501 356 0.027
Mouse
heterocycle catabolic process GO:0046700 280 0.027
organic cyclic compound catabolic process GO:1901361 295 0.027
interleukin 1 production GO:0032612 31 0.027
Mouse
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.027
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.027
sphingolipid catabolic process GO:0030149 7 0.027
nucleoside catabolic process GO:0009164 206 0.027
macromolecule catabolic process GO:0009057 281 0.027
Mouse
cell activation involved in immune response GO:0002263 126 0.026
positive regulation of peptidase activity GO:0010952 49 0.026
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
leukocyte apoptotic process GO:0071887 71 0.026
Mouse
cellular chemical homeostasis GO:0055082 215 0.026
Human Mouse
regulation of interferon gamma production GO:0032649 57 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
regulation of protein localization GO:0032880 231 0.025
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.025
regulation of cytokine production GO:0001817 266 0.025
Mouse
maintenance of location GO:0051235 89 0.025
Mouse
leukocyte differentiation GO:0002521 342 0.025
defense response to bacterium GO:0042742 119 0.025
Mouse
regulation of defense response GO:0031347 233 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
ceramide metabolic process GO:0006672 31 0.024
Mouse
organic anion transport GO:0015711 137 0.024
Mouse
aromatic compound catabolic process GO:0019439 286 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
Human Mouse
response to extracellular stimulus GO:0009991 127 0.024
Mouse
organic acid transport GO:0015849 101 0.024
Mouse
regulation of secretion by cell GO:1903530 249 0.024
Mouse
nucleotide metabolic process GO:0009117 332 0.024
antigen processing and presentation of exogenous antigen GO:0019884 26 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
interleukin 1 secretion GO:0050701 16 0.023
Mouse
transition metal ion transport GO:0000041 38 0.023
response to endoplasmic reticulum stress GO:0034976 53 0.023
glycoprotein metabolic process GO:0009100 116 0.023
negative regulation of lymphocyte proliferation GO:0050672 45 0.023
cellular homeostasis GO:0019725 240 0.023
Human Mouse
regulation of body fluid levels GO:0050878 162 0.022
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.022
multicellular organismal signaling GO:0035637 91 0.022
neuronal action potential GO:0019228 54 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
Human Mouse
negative regulation of cytokine production GO:0001818 84 0.022
leukocyte activation involved in immune response GO:0002366 126 0.022
regulation of cell activation GO:0050865 289 0.022
cellular response to lipid GO:0071396 145 0.022
nucleoside metabolic process GO:0009116 246 0.022
positive regulation of defense response GO:0031349 124 0.022
positive regulation of immune effector process GO:0002699 107 0.021
Mouse
regulation of protein secretion GO:0050708 82 0.021
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
Mouse
regulation of binding GO:0051098 111 0.021
regulation of t cell activation GO:0050863 170 0.021
anatomical structure homeostasis GO:0060249 145 0.021
Mouse
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.021
Mouse
interleukin 8 production GO:0032637 4 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
Human Mouse
antigen processing and presentation GO:0019882 47 0.021
production of molecular mediator of immune response GO:0002440 103 0.021
regulation of hydrolase activity GO:0051336 246 0.021
Mouse
cellular ion homeostasis GO:0006873 165 0.021
Human Mouse
cellular protein catabolic process GO:0044257 155 0.020
peptidyl amino acid modification GO:0018193 336 0.020
calcium ion transmembrane transport GO:0070588 85 0.020
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.020
vesicle organization GO:0016050 60 0.020
Mouse
cytoplasmic transport GO:0016482 234 0.020
Human Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.019
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.019
negative regulation of t cell activation GO:0050868 65 0.019
neurotransmitter transport GO:0006836 76 0.019
Mouse
interferon gamma production GO:0032609 67 0.019
peptidyl tyrosine modification GO:0018212 145 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
Mouse
muscle system process GO:0003012 141 0.019
Human Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.019
tissue homeostasis GO:0001894 115 0.019
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.018
Mouse
membrane lipid metabolic process GO:0006643 53 0.018
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.018
lipid transport GO:0006869 98 0.018
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
t cell mediated cytotoxicity GO:0001913 26 0.018
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.018
Mouse
negative regulation of cellular component organization GO:0051129 194 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
positive regulation of interleukin 1 beta production GO:0032731 16 0.018
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.018
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
response to organic cyclic compound GO:0014070 198 0.018
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
cytokine secretion GO:0050663 72 0.018
Mouse
cell recognition GO:0008037 83 0.017
glucose homeostasis GO:0042593 128 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
regulation of homeostatic process GO:0032844 182 0.017
Human Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
Mouse
purine nucleotide catabolic process GO:0006195 211 0.017
multi multicellular organism process GO:0044706 109 0.017
Mouse
epithelial cell proliferation GO:0050673 174 0.017
angiogenesis GO:0001525 201 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
regulation of cellular response to stress GO:0080135 159 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
positive regulation of interferon gamma production GO:0032729 39 0.017
regulation of inflammatory response GO:0050727 147 0.017
glial cell apoptotic process GO:0034349 3 0.016
locomotory behavior GO:0007626 195 0.016
regulation of system process GO:0044057 200 0.016
Human Mouse
positive regulation of macroautophagy GO:0016239 3 0.016
t cell differentiation GO:0030217 174 0.016
macromolecule glycosylation GO:0043413 55 0.016
neuron death GO:0070997 154 0.016
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.016
Mouse
cytokine biosynthetic process GO:0042089 68 0.016
purine containing compound catabolic process GO:0072523 213 0.016
nucleotide catabolic process GO:0009166 217 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
wound healing GO:0042060 157 0.015
Mouse
regulation of lymphocyte activation GO:0051249 240 0.015
positive regulation of secretion GO:0051047 130 0.015
Mouse
endomembrane system organization GO:0010256 147 0.015
Mouse
synaptic transmission GO:0007268 329 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
extracellular structure organization GO:0043062 148 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
atp metabolic process GO:0046034 75 0.015
action potential GO:0001508 78 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
regulation of postsynaptic membrane potential GO:0060078 48 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
spermatogenesis GO:0007283 284 0.015
transition metal ion homeostasis GO:0055076 54 0.015
positive regulation of protein modification process GO:0031401 299 0.015
Mouse
negative regulation of response to wounding GO:1903035 77 0.015
response to inorganic substance GO:0010035 96 0.015
Mouse
biomineral tissue development GO:0031214 64 0.015
Mouse
regulation of neuron death GO:1901214 134 0.015
positive regulation of interleukin 1 alpha production GO:0032730 4 0.015
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.015
antigen processing and presentation of peptide antigen GO:0048002 29 0.015
regulation of response to wounding GO:1903034 189 0.014
negative regulation of t cell proliferation GO:0042130 38 0.014
positive regulation of transferase activity GO:0051347 167 0.014
Mouse
extracellular matrix organization GO:0030198 147 0.014
calcium ion homeostasis GO:0055074 127 0.014
Human Mouse
iron ion import into cell GO:0097459 4 0.014
lipid localization GO:0010876 126 0.014
Mouse
membrane lipid biosynthetic process GO:0046467 32 0.014
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.014
lung development GO:0030324 164 0.014
fertilization GO:0009566 127 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
cell adhesion GO:0007155 329 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
cellular response to extracellular stimulus GO:0031668 81 0.014
Mouse
inflammatory response GO:0006954 244 0.014
Mouse
negative regulation of nervous system development GO:0051961 156 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
interleukin 6 production GO:0032635 58 0.014
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.014
regulation of cell cycle GO:0051726 281 0.014
positive regulation of cell activation GO:0050867 158 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
Human Mouse
immune response regulating signaling pathway GO:0002764 125 0.013
regulation of kinase activity GO:0043549 249 0.013
Mouse
purine nucleoside metabolic process GO:0042278 241 0.013
membrane organization GO:0061024 245 0.013
Mouse
nitric oxide metabolic process GO:0046209 25 0.013
anion transmembrane transport GO:0098656 71 0.013
interleukin 1 beta secretion GO:0050702 16 0.013
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.013
positive regulation of innate immune response GO:0045089 80 0.013
myelination GO:0042552 74 0.013
neurotransmitter secretion GO:0007269 62 0.013
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.013
negative regulation of defense response GO:0031348 77 0.013
regulation of ossification GO:0030278 112 0.013
Mouse
regulation of cytokine secretion GO:0050707 61 0.013
Mouse
negative regulation of immune effector process GO:0002698 55 0.013
positive regulation of protein secretion GO:0050714 52 0.013
Mouse
glycosphingolipid catabolic process GO:0046479 5 0.013
protein oligomerization GO:0051259 67 0.013
Mouse
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.013
regulation of proteolysis GO:0030162 164 0.013
Mouse
negative regulation of hypersensitivity GO:0002884 3 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
organelle assembly GO:0070925 177 0.013
Mouse
innate immune response GO:0045087 157 0.013
macroautophagy GO:0016236 21 0.013
learning or memory GO:0007611 148 0.013
lateral inhibition GO:0046331 1 0.013
lymphocyte proliferation GO:0046651 164 0.012
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.012
blood vessel morphogenesis GO:0048514 285 0.012
sequestering of calcium ion GO:0051208 18 0.012
Mouse
dicarboxylic acid transport GO:0006835 29 0.012
Mouse
response to acid chemical GO:0001101 111 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
Mouse
nitric oxide biosynthetic process GO:0006809 25 0.012
small molecule catabolic process GO:0044282 71 0.012
muscle contraction GO:0006936 101 0.012
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
establishment of vesicle localization GO:0051650 81 0.012
Mouse
exocytosis GO:0006887 121 0.012
Mouse
negative regulation of molecular function GO:0044092 258 0.012
regulation of neuron differentiation GO:0045664 281 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
phospholipid transport GO:0015914 21 0.012
Mouse
neuron apoptotic process GO:0051402 142 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
cytokine production involved in immune response GO:0002367 34 0.012
detection of stimulus GO:0051606 84 0.012
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
Mouse
gtp metabolic process GO:0046039 144 0.012
lipid catabolic process GO:0016042 69 0.012
regulation of protein transport GO:0051223 163 0.012
Mouse
protein secretion GO:0009306 111 0.012
Mouse
leukocyte proliferation GO:0070661 172 0.012
Mouse
negative regulation of leukocyte proliferation GO:0070664 46 0.012
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
establishment of synaptic vesicle localization GO:0097480 57 0.012
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.012
Human Mouse
neuromuscular process GO:0050905 99 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
Mouse
sterol transport GO:0015918 38 0.012
coagulation GO:0050817 78 0.012
Mouse
regulation of protein maturation GO:1903317 96 0.012
regulation of interleukin 1 beta production GO:0032651 25 0.012
Mouse
defense response to other organism GO:0098542 197 0.012
Mouse
viral process GO:0016032 41 0.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.012
Mouse
nucleoside monophosphate metabolic process GO:0009123 85 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.011
developmental maturation GO:0021700 193 0.011
organelle membrane fusion GO:0090174 1 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
lymphocyte apoptotic process GO:0070227 54 0.011
Mouse
epidermis development GO:0008544 187 0.011
regulation of t cell mediated cytotoxicity GO:0001914 18 0.011
Mouse
skin development GO:0043588 220 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
response to starvation GO:0042594 65 0.011
interleukin 2 production GO:0032623 33 0.011
respiratory system development GO:0060541 190 0.011
adult behavior GO:0030534 135 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
Mouse
negative regulation of proteolysis GO:0045861 74 0.011
regulation of mapk cascade GO:0043408 248 0.011
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
negative regulation of immune system process GO:0002683 209 0.011
positive regulation of protein transport GO:0051222 93 0.011
Mouse
ear development GO:0043583 200 0.011
cytokine metabolic process GO:0042107 71 0.011
acute inflammatory response GO:0002526 41 0.011
regulation of interleukin 1 production GO:0032652 26 0.011
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.011
Mouse
immune response inhibiting signal transduction GO:0002765 4 0.011
phagolysosome assembly GO:0001845 3 0.011
Mouse
adult locomotory behavior GO:0008344 91 0.011
negative regulation of interleukin 8 production GO:0032717 1 0.010
multicellular organismal metabolic process GO:0044236 28 0.010
Mouse
cognition GO:0050890 149 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
dephosphorylation GO:0016311 129 0.010
synaptic vesicle localization GO:0097479 59 0.010
Mouse
positive regulation of t cell mediated immunity GO:0002711 24 0.010
Mouse
response to topologically incorrect protein GO:0035966 25 0.010
oligosaccharide catabolic process GO:0009313 2 0.010
glucosamine containing compound metabolic process GO:1901071 3 0.010
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.010
atp catabolic process GO:0006200 55 0.010
regulation of t cell proliferation GO:0042129 92 0.010
regulation of acute inflammatory response GO:0002673 27 0.010
cellular amide metabolic process GO:0043603 58 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
monosaccharide metabolic process GO:0005996 106 0.010
icosanoid secretion GO:0032309 12 0.010
Mouse

P2rx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.596
inherited metabolic disorder DOID:655 0 0.596
disease of anatomical entity DOID:7 0 0.160
nervous system disease DOID:863 0 0.160
central nervous system disease DOID:331 0 0.096
sensory system disease DOID:0050155 0 0.031
eye and adnexa disease DOID:1492 0 0.022
retinal disease DOID:5679 0 0.021
eye disease DOID:5614 0 0.021
lysosomal storage disease DOID:3211 0 0.019
lipid storage disease DOID:9455 0 0.018
immune system disease DOID:2914 0 0.018
cerebral degeneration DOID:1443 0 0.015
brain disease DOID:936 0 0.015
retinal degeneration DOID:8466 0 0.014
neuropathy DOID:870 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
disease of mental health DOID:150 0 0.013
sphingolipidosis DOID:1927 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
vascular disease DOID:178 0 0.010
cardiovascular system disease DOID:1287 0 0.010
bone disease DOID:0080001 0 0.010