Mus musculus

61 known processes

Klf16

Kruppel-like factor 16

(Aliases: BTEB4,AI843742,DRRF)

Klf16 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.091
regulation of cellular amine metabolic process GO:0033238 20 0.079
dna metabolic process GO:0006259 303 0.067
cellular ketone metabolic process GO:0042180 84 0.060
spermatogenesis GO:0007283 284 0.058
cellular amino acid metabolic process GO:0006520 103 0.052
camera type eye development GO:0043010 266 0.052
amine metabolic process GO:0009308 45 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.051
cellular macromolecule catabolic process GO:0044265 206 0.051
myeloid cell differentiation GO:0030099 233 0.050
Mouse
cellular amine metabolic process GO:0044106 44 0.050
fat cell differentiation GO:0045444 160 0.048
male gamete generation GO:0048232 285 0.045
purine containing compound metabolic process GO:0072521 311 0.045
striated muscle tissue development GO:0014706 293 0.044
regulation of cellular catabolic process GO:0031329 242 0.044
cation transport GO:0006812 399 0.043
ras protein signal transduction GO:0007265 77 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
hematopoietic progenitor cell differentiation GO:0002244 143 0.042
skeletal system development GO:0001501 356 0.041
regulation of hydrolase activity GO:0051336 246 0.041
cell adhesion GO:0007155 329 0.041
cell division GO:0051301 120 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
cellular protein catabolic process GO:0044257 155 0.040
purine ribonucleoside metabolic process GO:0046128 241 0.039
nucleotide metabolic process GO:0009117 332 0.038
ion transmembrane transport GO:0034220 361 0.038
regulation of organelle organization GO:0033043 289 0.037
anatomical structure homeostasis GO:0060249 145 0.036
macromolecule catabolic process GO:0009057 281 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.035
rho protein signal transduction GO:0007266 32 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
negative regulation of molecular function GO:0044092 258 0.035
chromatin modification GO:0016568 187 0.035
muscle tissue development GO:0060537 308 0.034
connective tissue development GO:0061448 179 0.034
cytoplasmic transport GO:0016482 234 0.034
wnt signaling pathway GO:0016055 188 0.033
multicellular organismal homeostasis GO:0048871 164 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
gonad development GO:0008406 141 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
apoptotic signaling pathway GO:0097190 306 0.032
energy homeostasis GO:0097009 15 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
ubiquitin dependent protein catabolic process GO:0006511 129 0.031
organelle fission GO:0048285 170 0.031
protein localization to nucleus GO:0034504 121 0.030
cellular homeostasis GO:0019725 240 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
Mouse
glycosyl compound metabolic process GO:1901657 246 0.030
mitotic cell cycle process GO:1903047 159 0.030
transmembrane transport GO:0055085 412 0.030
regulation of cell cycle GO:0051726 281 0.029
cell growth GO:0016049 130 0.029
regulation of wnt signaling pathway GO:0030111 123 0.029
modification dependent protein catabolic process GO:0019941 133 0.028
myeloid cell homeostasis GO:0002262 114 0.028
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.028
gland development GO:0048732 330 0.028
homeostasis of number of cells GO:0048872 210 0.028
Mouse
lymphocyte differentiation GO:0030098 242 0.028
protein catabolic process GO:0030163 221 0.027
mapk cascade GO:0000165 281 0.027
respiratory system development GO:0060541 190 0.027
regulation of system process GO:0044057 200 0.027
ribonucleoside metabolic process GO:0009119 245 0.026
carbohydrate metabolic process GO:0005975 230 0.026
nitrogen compound transport GO:0071705 271 0.026
heterochromatin organization GO:0070828 4 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
proteasomal protein catabolic process GO:0010498 98 0.026
heterocycle catabolic process GO:0046700 280 0.026
immune effector process GO:0002252 321 0.026
microtubule based process GO:0007017 236 0.025
chromatin organization GO:0006325 206 0.025
positive regulation of cellular catabolic process GO:0031331 148 0.025
b cell activation GO:0042113 161 0.025
compound eye development GO:0048749 1 0.024
protein localization to organelle GO:0033365 185 0.024
maintenance of location GO:0051235 89 0.024
canonical wnt signaling pathway GO:0060070 130 0.024
sensory perception GO:0007600 245 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
peptidyl amino acid modification GO:0018193 336 0.023
regulation of ion transport GO:0043269 215 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
cellular lipid metabolic process GO:0044255 323 0.023
regulation of asymmetric cell division GO:0009786 4 0.022
positive regulation of protein modification process GO:0031401 299 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
axonogenesis GO:0007409 274 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
single organism cell adhesion GO:0098602 156 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
meiotic nuclear division GO:0007126 115 0.021
leukocyte differentiation GO:0002521 342 0.021
lung development GO:0030324 164 0.021
regulation of transferase activity GO:0051338 263 0.021
digestive system development GO:0055123 200 0.021
regulation of mapk cascade GO:0043408 248 0.021
cellular chemical homeostasis GO:0055082 215 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
aromatic compound catabolic process GO:0019439 286 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
cation transmembrane transport GO:0098655 266 0.020
regulation of transmembrane transport GO:0034762 128 0.020
lateral inhibition GO:0046331 1 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
t cell differentiation GO:0030217 174 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
regulation of intracellular transport GO:0032386 159 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.020
anion transport GO:0006820 177 0.020
epithelial tube morphogenesis GO:0060562 303 0.019
regulation of secretion GO:0051046 274 0.019
cell activation involved in immune response GO:0002263 126 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
meiotic cell cycle GO:0051321 122 0.019
regulation of protein localization GO:0032880 231 0.019
endocytosis GO:0006897 168 0.019
inflammatory response GO:0006954 244 0.019
multicellular organismal signaling GO:0035637 91 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
germ cell development GO:0007281 185 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
habituation GO:0046959 3 0.019
blood vessel morphogenesis GO:0048514 285 0.019
regulation of fat cell differentiation GO:0045598 81 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
protein ubiquitination GO:0016567 171 0.019
skeletal system morphogenesis GO:0048705 203 0.019
mitotic cell cycle GO:0000278 195 0.018
respiratory tube development GO:0030323 167 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
circulatory system process GO:0003013 197 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
regulation of epithelial cell proliferation GO:0050678 141 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
organophosphate catabolic process GO:0046434 232 0.018
nucleotide catabolic process GO:0009166 217 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
intracellular protein transport GO:0006886 204 0.018
regulation of defense response GO:0031347 233 0.018
b cell differentiation GO:0030183 78 0.018
cell type specific apoptotic process GO:0097285 268 0.018
retrograde transport endosome to golgi GO:0042147 2 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
nuclear division GO:0000280 158 0.018
positive regulation of cell cycle GO:0045787 92 0.018
regulation of cell activation GO:0050865 289 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
mitotic chromosome condensation GO:0007076 1 0.018
kidney development GO:0001822 213 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
t cell activation GO:0042110 289 0.017
nucleoside metabolic process GO:0009116 246 0.017
protein acylation GO:0043543 64 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
regulation of response to wounding GO:1903034 189 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
sensory organ morphogenesis GO:0090596 242 0.017
sequestering of calcium ion GO:0051208 18 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
peptide secretion GO:0002790 114 0.017
peptide transport GO:0015833 133 0.017
wound healing GO:0042060 157 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
rhythmic process GO:0048511 174 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
response to monosaccharide GO:0034284 67 0.016
protein import GO:0017038 101 0.016
sequestering of metal ion GO:0051238 19 0.016
blood circulation GO:0008015 195 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
nucleoside catabolic process GO:0009164 206 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
regulation of anatomical structure size GO:0090066 178 0.016
regulation of clathrin mediated endocytosis GO:2000369 4 0.016
amide transport GO:0042886 138 0.016
rac protein signal transduction GO:0016601 13 0.016
exocytosis GO:0006887 121 0.016
regionalization GO:0003002 337 0.016
negative regulation of synapse assembly GO:0051964 3 0.016
regulation of cell cycle process GO:0010564 160 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
protein alkylation GO:0008213 81 0.016
nuclear import GO:0051170 95 0.016
actin cytoskeleton organization GO:0030036 220 0.016
ossification GO:0001503 216 0.016
regulation of protein kinase activity GO:0045859 232 0.016
oocyte construction GO:0007308 2 0.015
transmission of nerve impulse GO:0019226 76 0.015
organ growth GO:0035265 117 0.015
regulation of homeostatic process GO:0032844 182 0.015
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
heart contraction GO:0060047 93 0.015
regulation of canonical wnt signaling pathway GO:0060828 82 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
development of primary sexual characteristics GO:0045137 143 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
organelle localization GO:0051640 179 0.015
response to radiation GO:0009314 165 0.015
cytokine production GO:0001816 319 0.015
digestive tract development GO:0048565 190 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
oxidation reduction process GO:0055114 342 0.015
muscle system process GO:0003012 141 0.015
angiogenesis GO:0001525 201 0.015
rap protein signal transduction GO:0032486 3 0.015
epithelial cell proliferation GO:0050673 174 0.015
histone modification GO:0016570 159 0.015
methylation GO:0032259 134 0.014
hexose metabolic process GO:0019318 98 0.014
regulation of cell migration GO:0030334 219 0.014
cartilage development GO:0051216 140 0.014
response to growth factor GO:0070848 198 0.014
urogenital system development GO:0001655 261 0.014
regulation of membrane potential GO:0042391 192 0.014
protein methylation GO:0006479 81 0.014
peptide hormone secretion GO:0030072 109 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
response to lipopolysaccharide GO:0032496 128 0.014
single organism nuclear import GO:1902593 95 0.014
spermatid development GO:0007286 108 0.014
hormone secretion GO:0046879 128 0.014
erythrocyte differentiation GO:0030218 88 0.014
Mouse
placenta development GO:0001890 140 0.014
phospholipid metabolic process GO:0006644 87 0.014
covalent chromatin modification GO:0016569 163 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
regulation of secretion by cell GO:1903530 249 0.014
negative regulation of immune system process GO:0002683 209 0.014
Mouse
blastocyst development GO:0001824 80 0.014
muscle cell differentiation GO:0042692 261 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
cell fate commitment GO:0045165 210 0.014
histone methylation GO:0016571 71 0.014
chromosome segregation GO:0007059 48 0.014
regulation of hormone levels GO:0010817 211 0.014
dna packaging GO:0006323 30 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
synaptic transmission GO:0007268 329 0.014
regulation of cellular protein catabolic process GO:1903362 61 0.013
dna endoreduplication GO:0042023 4 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
adult behavior GO:0030534 135 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
dna repair GO:0006281 107 0.013
lens development in camera type eye GO:0002088 62 0.013
regulation of cell motility GO:2000145 236 0.013
pharynx development GO:0060465 1 0.013
skeletal muscle organ development GO:0060538 163 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
carbohydrate homeostasis GO:0033500 128 0.013
nuclear transport GO:0051169 139 0.013
neuron death GO:0070997 154 0.013
negative regulation of cell size GO:0045792 3 0.013
cell cell junction organization GO:0045216 72 0.013
leukocyte mediated immunity GO:0002443 174 0.013
gastrulation GO:0007369 116 0.013
tube formation GO:0035148 140 0.013
regulation of protein transport GO:0051223 163 0.013
bone morphogenesis GO:0060349 78 0.013
cation homeostasis GO:0055080 212 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
liver development GO:0001889 66 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
neural tube development GO:0021915 160 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of binding GO:0051098 111 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
protein import into nucleus GO:0006606 95 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
glucose metabolic process GO:0006006 92 0.013
response to organonitrogen compound GO:0010243 246 0.013
dna conformation change GO:0071103 37 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
myosin filament assembly GO:0031034 2 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
positive regulation of transferase activity GO:0051347 167 0.012
regulation of inflammatory response GO:0050727 147 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
chondrocyte differentiation GO:0002062 72 0.012
action potential GO:0001508 78 0.012
calcium ion transport GO:0006816 159 0.012
spermatid differentiation GO:0048515 115 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
protein targeting GO:0006605 143 0.012
epithelial tube formation GO:0072175 130 0.012
muscle cell development GO:0055001 133 0.012
limb morphogenesis GO:0035108 149 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
digestive tract morphogenesis GO:0048546 147 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
tissue remodeling GO:0048771 102 0.012
chondrocyte development GO:0002063 24 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
endomembrane system organization GO:0010256 147 0.012
insulin secretion GO:0030073 89 0.012
small molecule biosynthetic process GO:0044283 132 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
divalent inorganic cation transport GO:0072511 178 0.012
positive regulation of organelle organization GO:0010638 128 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
developmental maturation GO:0021700 193 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
meiotic cell cycle process GO:1903046 77 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
muscle contraction GO:0006936 101 0.012
oocyte axis specification GO:0007309 2 0.012
adaptive immune response GO:0002250 155 0.011
regulation of ossification GO:0030278 112 0.011
bone remodeling GO:0046849 53 0.011
regulation of embryonic development GO:0045995 71 0.011
chondrocyte hypertrophy GO:0003415 4 0.011
membrane organization GO:0061024 245 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular response to carbohydrate stimulus GO:0071322 50 0.011
palate development GO:0060021 76 0.011
rna processing GO:0006396 105 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
regulation of muscle tissue development GO:1901861 97 0.011
positive regulation of cell development GO:0010720 237 0.011
cardiocyte differentiation GO:0035051 87 0.011
glucose homeostasis GO:0042593 128 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
hepaticobiliary system development GO:0061008 67 0.011
rna interference GO:0016246 2 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
glycerolipid metabolic process GO:0046486 122 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of cell cycle g2 m phase transition GO:1902749 10 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
regulation of metal ion transport GO:0010959 106 0.011
actin filament organization GO:0007015 113 0.011
tube closure GO:0060606 91 0.011
regulation of blood pressure GO:0008217 93 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
response to extracellular stimulus GO:0009991 127 0.011
embryonic placenta development GO:0001892 98 0.011
cellular calcium ion homeostasis GO:0006874 119 0.010
cardiac muscle tissue development GO:0048738 130 0.010
cellular protein complex assembly GO:0043623 116 0.010
neuronal action potential GO:0019228 54 0.010
mitotic nuclear division GO:0007067 48 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
purine containing compound catabolic process GO:0072523 213 0.010
negative regulation of cell activation GO:0050866 111 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
branching morphogenesis of an epithelial tube GO:0048754 159 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
positive regulation of cell death GO:0010942 224 0.010
embryonic appendage morphogenesis GO:0035113 126 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
regulation of cytokine production GO:0001817 266 0.010
dephosphorylation GO:0016311 129 0.010
gliogenesis GO:0042063 141 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
ribonucleotide biosynthetic process GO:0009260 59 0.010
regulation of cell division GO:0051302 76 0.010
calcium ion homeostasis GO:0055074 127 0.010
heart morphogenesis GO:0003007 178 0.010
phagocytosis GO:0006909 66 0.010
cognition GO:0050890 149 0.010
tissue homeostasis GO:0001894 115 0.010
negative regulation of transferase activity GO:0051348 85 0.010
myosin filament organization GO:0031033 3 0.010

Klf16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.018
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
musculoskeletal system disease DOID:17 0 0.013