Mus musculus

19 known processes

Hps5

Hermansky-Pudlak syndrome 5 homolog (human)

(Aliases: hz,C85120,MGC99886,maroon,AI646796,haze,mr,ru2,AL022647,ru-2)

Hps5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigment accumulation GO:0043476 1 1.000
establishment of melanosome localization GO:0032401 11 0.993
pigment granule localization GO:0051875 13 0.967
melanosome transport GO:0032402 11 0.925
melanosome localization GO:0032400 12 0.922
coagulation GO:0050817 78 0.902
melanosome organization GO:0032438 8 0.853
anterograde synaptic vesicle transport GO:0048490 15 0.844
anterograde axon cargo transport GO:0008089 20 0.826
microtubule based transport GO:0010970 50 0.825
blood coagulation GO:0007596 76 0.790
microtubule based movement GO:0007018 84 0.773
hemostasis GO:0007599 78 0.766
pigment granule transport GO:0051904 12 0.731
regulation of natural killer cell activation GO:0032814 22 0.712
vesicle localization GO:0051648 86 0.687
cytoskeleton dependent intracellular transport GO:0030705 50 0.679
pigment cell differentiation GO:0050931 27 0.629
pigmentation GO:0043473 71 0.627
cellular pigmentation GO:0033059 20 0.583
secretion of lysosomal enzymes GO:0033299 6 0.555
melanocyte differentiation GO:0030318 25 0.550
regulation of body fluid levels GO:0050878 162 0.525
developmental pigmentation GO:0048066 40 0.492
Zebrafish
synaptic vesicle localization GO:0097479 59 0.436
secretory granule organization GO:0033363 20 0.400
establishment of vesicle localization GO:0051650 81 0.383
establishment of organelle localization GO:0051656 122 0.353
axon cargo transport GO:0008088 33 0.345
natural killer cell degranulation GO:0043320 3 0.329
pigment granule organization GO:0048753 9 0.316
natural killer cell activation GO:0030101 44 0.312
organelle localization GO:0051640 179 0.304
synaptic transmission GO:0007268 329 0.303
lytic vacuole organization GO:0080171 21 0.284
positive regulation of natural killer cell activation GO:0032816 15 0.283
vesicle organization GO:0016050 60 0.273
positive regulation of lymphocyte activation GO:0051251 140 0.272
wound healing GO:0042060 157 0.268
natural killer cell activation involved in immune response GO:0002323 10 0.245
establishment of synaptic vesicle localization GO:0097480 57 0.220
regulation of pigment cell differentiation GO:0050932 7 0.181
establishment of pigment granule localization GO:0051905 12 0.175
microtubule based process GO:0007017 236 0.174
regulation of lymphocyte activation GO:0051249 240 0.165
synaptic vesicle transport GO:0048489 57 0.153
endomembrane system organization GO:0010256 147 0.148
neuroepithelial cell differentiation GO:0060563 37 0.146
positive regulation of cell activation GO:0050867 158 0.144
organophosphate catabolic process GO:0046434 232 0.142
regulation of cell activation GO:0050865 289 0.121
cellular nitrogen compound catabolic process GO:0044270 280 0.120
nucleoside phosphate catabolic process GO:1901292 222 0.092
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.090
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.088
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.084
lysosome organization GO:0007040 21 0.083
nucleoside phosphate metabolic process GO:0006753 338 0.082
nucleotide metabolic process GO:0009117 332 0.081
purine nucleoside metabolic process GO:0042278 241 0.076
purine nucleotide metabolic process GO:0006163 302 0.073
antigen processing and presentation of lipid antigen via mhc class ib GO:0048003 3 0.072
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.071
nucleoside catabolic process GO:0009164 206 0.070
purine containing compound metabolic process GO:0072521 311 0.068
leukocyte differentiation GO:0002521 342 0.067
transmembrane transport GO:0055085 412 0.067
exosomal secretion GO:1990182 1 0.066
purine nucleoside triphosphate metabolic process GO:0009144 226 0.065
nucleoside triphosphate metabolic process GO:0009141 230 0.062
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
ribose phosphate metabolic process GO:0019693 291 0.061
purine nucleoside triphosphate catabolic process GO:0009146 203 0.059
ribonucleoside metabolic process GO:0009119 245 0.059
cytoplasmic transport GO:0016482 234 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.057
organonitrogen compound catabolic process GO:1901565 264 0.055
organic cyclic compound catabolic process GO:1901361 295 0.054
ribonucleoside catabolic process GO:0042454 206 0.054
nucleoside metabolic process GO:0009116 246 0.054
cellular lipid metabolic process GO:0044255 323 0.054
eye pigmentation GO:0048069 3 0.053
Zebrafish
ribonucleotide metabolic process GO:0009259 291 0.053
regulation of cellular catabolic process GO:0031329 242 0.052
purine ribonucleotide metabolic process GO:0009150 290 0.051
regulation of lymphocyte differentiation GO:0045619 107 0.051
purine nucleotide catabolic process GO:0006195 211 0.051
camera type eye development GO:0043010 266 0.049
glycosyl compound metabolic process GO:1901657 246 0.049
aromatic compound catabolic process GO:0019439 286 0.048
purine nucleoside catabolic process GO:0006152 205 0.045
cytotoxic t cell degranulation GO:0043316 2 0.044
heterocycle catabolic process GO:0046700 280 0.044
protein targeting GO:0006605 143 0.044
cellular protein catabolic process GO:0044257 155 0.043
purine ribonucleoside catabolic process GO:0046130 205 0.043
gtp metabolic process GO:0046039 144 0.043
neuromuscular process GO:0050905 99 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
glycosyl compound catabolic process GO:1901658 206 0.042
cation transmembrane transport GO:0098655 266 0.042
lymphocyte mediated immunity GO:0002449 139 0.041
protein targeting to vacuole GO:0006623 3 0.041
nitrogen compound transport GO:0071705 271 0.040
vacuole organization GO:0007033 38 0.039
nucleotide catabolic process GO:0009166 217 0.039
reactive oxygen species biosynthetic process GO:1903409 8 0.038
ribonucleotide catabolic process GO:0009261 208 0.038
immune effector process GO:0002252 321 0.038
purine ribonucleotide catabolic process GO:0009154 208 0.038
purine ribonucleoside metabolic process GO:0046128 241 0.038
t cell differentiation GO:0030217 174 0.038
regulation of reactive oxygen species metabolic process GO:2000377 40 0.038
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
carbohydrate derivative catabolic process GO:1901136 231 0.037
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
macromolecule catabolic process GO:0009057 281 0.035
inorganic ion transmembrane transport GO:0098660 234 0.035
membrane organization GO:0061024 245 0.035
reactive oxygen species metabolic process GO:0072593 84 0.034
lipid homeostasis GO:0055088 63 0.034
establishment of protein localization to vacuole GO:0072666 4 0.033
lipid localization GO:0010876 126 0.033
regulation of endocytosis GO:0030100 69 0.032
protein localization to vacuole GO:0072665 4 0.032
intracellular protein transport GO:0006886 204 0.031
defense response to bacterium GO:0042742 119 0.031
natural killer cell mediated cytotoxicity GO:0042267 29 0.030
protein secretion GO:0009306 111 0.030
t cell activation GO:0042110 289 0.029
positive regulation of cellular catabolic process GO:0031331 148 0.028
positive regulation of pigment cell differentiation GO:0050942 5 0.028
regulation of protein catabolic process GO:0042176 108 0.028
protein catabolic process GO:0030163 221 0.028
purine containing compound catabolic process GO:0072523 213 0.028
establishment of protein localization to organelle GO:0072594 118 0.028
positive regulation of phagocytosis GO:0050766 26 0.027
neuromuscular process controlling balance GO:0050885 59 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.026
cellular homeostasis GO:0019725 240 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
inorganic cation transmembrane transport GO:0098662 207 0.025
positive regulation of cellular protein catabolic process GO:1903364 34 0.025
regulation of purine nucleotide metabolic process GO:1900542 169 0.025
cell adhesion GO:0007155 329 0.025
adaptive immune response GO:0002250 155 0.025
cation transport GO:0006812 399 0.024
positive regulation of leukocyte differentiation GO:1902107 86 0.024
amine metabolic process GO:0009308 45 0.024
early endosome to late endosome transport GO:0045022 2 0.024
regulation of nucleotide metabolic process GO:0006140 169 0.024
cellular amine metabolic process GO:0044106 44 0.024
apoptotic signaling pathway GO:0097190 306 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
regulation of ion transport GO:0043269 215 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
phospholipid metabolic process GO:0006644 87 0.022
gtp catabolic process GO:0006184 143 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
protein targeting to lysosome GO:0006622 2 0.021
ear morphogenesis GO:0042471 118 0.021
carbohydrate metabolic process GO:0005975 230 0.021
endosome organization GO:0007032 9 0.021
ear development GO:0043583 200 0.021
regulation of cellular protein catabolic process GO:1903362 61 0.021
leukocyte mediated cytotoxicity GO:0001909 62 0.020
regulation of hydrolase activity GO:0051336 246 0.020
ion transmembrane transport GO:0034220 361 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
antigen processing and presentation GO:0019882 47 0.019
positive regulation of protein catabolic process GO:0045732 60 0.019
natural killer cell mediated immunity GO:0002228 29 0.019
sensory organ morphogenesis GO:0090596 242 0.019
guanosine containing compound catabolic process GO:1901069 144 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
lymphocyte differentiation GO:0030098 242 0.018
cation homeostasis GO:0055080 212 0.018
neurotransmitter transport GO:0006836 76 0.018
retina development in camera type eye GO:0060041 119 0.018
phagocytosis GO:0006909 66 0.018
cell activation involved in immune response GO:0002263 126 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
endocytosis GO:0006897 168 0.018
membrane fusion GO:0061025 38 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.017
protein maturation GO:0051604 176 0.017
cellular ketone metabolic process GO:0042180 84 0.017
regulation of alpha beta t cell activation GO:0046634 53 0.017
cellular ion homeostasis GO:0006873 165 0.017
platelet activation GO:0030168 40 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
maintenance of location GO:0051235 89 0.016
glucose homeostasis GO:0042593 128 0.016
interleukin 8 production GO:0032637 4 0.016
lipid biosynthetic process GO:0008610 179 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
innate immune response GO:0045087 157 0.016
regulation of t cell activation GO:0050863 170 0.016
protein localization to organelle GO:0033365 185 0.016
leukocyte mediated immunity GO:0002443 174 0.016
guanosine containing compound metabolic process GO:1901068 144 0.015
cell killing GO:0001906 67 0.015
chromatin modification GO:0016568 187 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
urogenital system development GO:0001655 261 0.015
myeloid cell differentiation GO:0030099 233 0.015
compound eye development GO:0048749 1 0.015
peptidyl amino acid modification GO:0018193 336 0.014
regulation of phagocytosis GO:0050764 33 0.014
alpha beta t cell differentiation GO:0046632 69 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
oxidation reduction process GO:0055114 342 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
platelet aggregation GO:0070527 20 0.014
divalent metal ion transport GO:0070838 172 0.014
protein processing GO:0016485 163 0.014
regulation of t cell differentiation GO:0045580 83 0.014
actin cytoskeleton organization GO:0030036 220 0.014
muscle tissue development GO:0060537 308 0.014
regulation of interleukin 8 production GO:0032677 3 0.013
cellular chemical homeostasis GO:0055082 215 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
pigment metabolic process GO:0042440 32 0.013
positive regulation of endocytosis GO:0045807 42 0.013
regulation of organelle organization GO:0033043 289 0.013
glycoprotein metabolic process GO:0009100 116 0.013
cytokine production GO:0001816 319 0.012
adult behavior GO:0030534 135 0.012
anion transport GO:0006820 177 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
organelle assembly GO:0070925 177 0.012
cell type specific apoptotic process GO:0097285 268 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
development of primary sexual characteristics GO:0045137 143 0.012
male gamete generation GO:0048232 285 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
neuronal action potential GO:0019228 54 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
neurotransmitter secretion GO:0007269 62 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
protein modification by small protein conjugation GO:0032446 187 0.011
regulation of proteolysis GO:0030162 164 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
positive regulation of lymphocyte differentiation GO:0045621 61 0.011
cellular protein complex assembly GO:0043623 116 0.011
protein ubiquitination GO:0016567 171 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
rna interference GO:0016246 2 0.011
t cell mediated immunity GO:0002456 50 0.011
response to extracellular stimulus GO:0009991 127 0.011
dephosphorylation GO:0016311 129 0.011
organic anion transport GO:0015711 137 0.011
renal system development GO:0072001 225 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
asymmetric stem cell division GO:0098722 3 0.011
positive regulation of t cell differentiation GO:0045582 52 0.011
wnt signaling pathway GO:0016055 188 0.011
regulation of secretion by cell GO:1903530 249 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
homotypic cell cell adhesion GO:0034109 28 0.011
positive regulation of secretion GO:0051047 130 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
tissue remodeling GO:0048771 102 0.011
calcium ion dependent exocytosis GO:0017156 35 0.011
hormone secretion GO:0046879 128 0.011
organic acid biosynthetic process GO:0016053 86 0.011
small molecule biosynthetic process GO:0044283 132 0.010
negative regulation of cell development GO:0010721 169 0.010
gonad development GO:0008406 141 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
sulfur compound biosynthetic process GO:0044272 37 0.010
positive regulation of interferon alpha production GO:0032727 4 0.010
positive regulation of protein modification process GO:0031401 299 0.010
ossification GO:0001503 216 0.010
myeloid leukocyte mediated immunity GO:0002444 42 0.010
glycerolipid metabolic process GO:0046486 122 0.010
regulation of exocytosis GO:0017157 61 0.010
positive regulation of developmental pigmentation GO:0048087 6 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
positive regulation of secretion by cell GO:1903532 114 0.010

Hps5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
immune system disease DOID:2914 0 0.025
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
connective tissue disease DOID:65 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
bone disease DOID:0080001 0 0.011