Mus musculus

33 known processes

Hps6

Hermansky-Pudlak syndrome 6

(Aliases: 5330434M19Rik,ru,MGC31055,BLOC2)

Hps6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigment accumulation GO:0043476 1 0.989
pigmentation GO:0043473 71 0.942
establishment of melanosome localization GO:0032401 11 0.926
melanosome organization GO:0032438 8 0.845
coagulation GO:0050817 78 0.833
pigment granule localization GO:0051875 13 0.832
melanocyte differentiation GO:0030318 25 0.807
hemostasis GO:0007599 78 0.783
anterograde axon cargo transport GO:0008089 20 0.782
microtubule based transport GO:0010970 50 0.774
microtubule based movement GO:0007018 84 0.749
pigment cell differentiation GO:0050931 27 0.721
regulation of natural killer cell activation GO:0032814 22 0.699
melanosome transport GO:0032402 11 0.628
regulation of body fluid levels GO:0050878 162 0.538
melanosome localization GO:0032400 12 0.534
secretion of lysosomal enzymes GO:0033299 6 0.503
wound healing GO:0042060 157 0.455
secretory granule organization GO:0033363 20 0.403
anterograde synaptic vesicle transport GO:0048490 15 0.383
vesicle organization GO:0016050 60 0.355
vesicle localization GO:0051648 86 0.355
cellular pigmentation GO:0033059 20 0.335
pigment granule transport GO:0051904 12 0.319
blood coagulation GO:0007596 76 0.301
neuroepithelial cell differentiation GO:0060563 37 0.300
pigment granule organization GO:0048753 9 0.296
synaptic vesicle transport GO:0048489 57 0.240
cytoskeleton dependent intracellular transport GO:0030705 50 0.228
developmental pigmentation GO:0048066 40 0.224
establishment of organelle localization GO:0051656 122 0.218
natural killer cell activation GO:0030101 44 0.201
pigment biosynthetic process GO:0046148 26 0.153
axon cargo transport GO:0008088 33 0.142
positive regulation of natural killer cell activation GO:0032816 15 0.123
regulation of lymphocyte activation GO:0051249 240 0.121
regulation of pigment cell differentiation GO:0050932 7 0.113
regulation of cell activation GO:0050865 289 0.108
establishment of vesicle localization GO:0051650 81 0.103
lytic vacuole organization GO:0080171 21 0.102
positive regulation of cell activation GO:0050867 158 0.094
establishment of synaptic vesicle localization GO:0097480 57 0.091
organelle localization GO:0051640 179 0.088
lysosome organization GO:0007040 21 0.084
eye pigmentation GO:0048069 3 0.078
synaptic vesicle localization GO:0097479 59 0.078
microtubule based process GO:0007017 236 0.072
natural killer cell degranulation GO:0043320 3 0.069
positive regulation of lymphocyte activation GO:0051251 140 0.066
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.054
synaptic transmission GO:0007268 329 0.051
nucleoside metabolic process GO:0009116 246 0.050
cellular amino acid metabolic process GO:0006520 103 0.048
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.048
protein targeting GO:0006605 143 0.047
establishment of pigment granule localization GO:0051905 12 0.047
natural killer cell activation involved in immune response GO:0002323 10 0.046
camera type eye development GO:0043010 266 0.044
aromatic compound catabolic process GO:0019439 286 0.042
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.042
protein targeting to vacuole GO:0006623 3 0.041
retina development in camera type eye GO:0060041 119 0.040
vacuole organization GO:0007033 38 0.039
nucleotide metabolic process GO:0009117 332 0.038
protein secretion GO:0009306 111 0.036
pigment metabolic process GO:0042440 32 0.035
ketone body metabolic process GO:1902224 3 0.035
leukocyte differentiation GO:0002521 342 0.035
cytoplasmic transport GO:0016482 234 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.034
alpha amino acid metabolic process GO:1901605 59 0.034
heterocycle catabolic process GO:0046700 280 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
nucleotide catabolic process GO:0009166 217 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
reactive oxygen species biosynthetic process GO:1903409 8 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
regulation of leukocyte differentiation GO:1902105 159 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
adaptive immune response GO:0002250 155 0.029
neuromuscular process controlling balance GO:0050885 59 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
cell adhesion GO:0007155 329 0.029
organic cyclic compound catabolic process GO:1901361 295 0.027
regulation of organelle organization GO:0033043 289 0.027
t cell activation GO:0042110 289 0.027
purine containing compound metabolic process GO:0072521 311 0.027
glycosyl compound metabolic process GO:1901657 246 0.026
nucleoside catabolic process GO:0009164 206 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
organic hydroxy compound transport GO:0015850 93 0.025
amine metabolic process GO:0009308 45 0.025
immune effector process GO:0002252 321 0.025
cation transport GO:0006812 399 0.025
cellular amine metabolic process GO:0044106 44 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
lymphocyte mediated immunity GO:0002449 139 0.024
purine nucleotide catabolic process GO:0006195 211 0.023
lipid localization GO:0010876 126 0.023
purine containing compound catabolic process GO:0072523 213 0.023
protein localization to vacuole GO:0072665 4 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
purine nucleoside catabolic process GO:0006152 205 0.022
t cell differentiation GO:0030217 174 0.022
antigen processing and presentation exogenous lipid antigen via mhc class ib GO:0048007 3 0.022
response to lipopolysaccharide GO:0032496 128 0.022
regulation of secretion by cell GO:1903530 249 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
stem cell proliferation GO:0072089 117 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
lymphocyte differentiation GO:0030098 242 0.021
apoptotic signaling pathway GO:0097190 306 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
transmembrane transport GO:0055085 412 0.021
antigen processing and presentation of lipid antigen via mhc class ib GO:0048003 3 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
positive regulation of cell development GO:0010720 237 0.021
cation transmembrane transport GO:0098655 266 0.021
placenta development GO:0001890 140 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
cell killing GO:0001906 67 0.020
glycoprotein metabolic process GO:0009100 116 0.020
cell activation involved in immune response GO:0002263 126 0.020
intracellular protein transport GO:0006886 204 0.020
cellular lipid metabolic process GO:0044255 323 0.019
compound eye development GO:0048749 1 0.019
fatty acid metabolic process GO:0006631 121 0.019
positive regulation of pigment cell differentiation GO:0050942 5 0.019
regulation of hydrolase activity GO:0051336 246 0.019
cellular ketone metabolic process GO:0042180 84 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
establishment of protein localization to vacuole GO:0072666 4 0.018
endomembrane system organization GO:0010256 147 0.018
regulation of lymphocyte differentiation GO:0045619 107 0.018
regulation of protein transport GO:0051223 163 0.018
dna metabolic process GO:0006259 303 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.018
defense response to bacterium GO:0042742 119 0.018
guanosine containing compound metabolic process GO:1901068 144 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
purine nucleoside metabolic process GO:0042278 241 0.017
regulation of ion transport GO:0043269 215 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
regulation of cellular amine metabolic process GO:0033238 20 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
actin cytoskeleton organization GO:0030036 220 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
cellular homeostasis GO:0019725 240 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
regulation of endocytosis GO:0030100 69 0.017
nitrogen compound transport GO:0071705 271 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
cytokine production GO:0001816 319 0.016
regulation of secretion GO:0051046 274 0.016
neuromuscular process GO:0050905 99 0.016
lipid homeostasis GO:0055088 63 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
positive regulation of nervous system development GO:0051962 221 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
sensory organ morphogenesis GO:0090596 242 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
gtp catabolic process GO:0006184 143 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
cell type specific apoptotic process GO:0097285 268 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
antigen processing and presentation GO:0019882 47 0.015
myeloid cell differentiation GO:0030099 233 0.015
oxidation reduction process GO:0055114 342 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
cation homeostasis GO:0055080 212 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
alpha beta t cell differentiation GO:0046632 69 0.015
regulation of defense response GO:0031347 233 0.014
protein maturation GO:0051604 176 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
positive regulation of protein modification process GO:0031401 299 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
protein processing GO:0016485 163 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
membrane organization GO:0061024 245 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
cellular ion homeostasis GO:0006873 165 0.013
defense response to other organism GO:0098542 197 0.013
regulation of inflammatory response GO:0050727 147 0.013
neuronal action potential GO:0019228 54 0.013
regulation of t cell activation GO:0050863 170 0.013
organophosphate catabolic process GO:0046434 232 0.013
ossification GO:0001503 216 0.013
regulation of t cell differentiation GO:0045580 83 0.013
protein catabolic process GO:0030163 221 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
cell division GO:0051301 120 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
chromatin modification GO:0016568 187 0.013
ras protein signal transduction GO:0007265 77 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
maintenance of location GO:0051235 89 0.013
regulation of protein localization GO:0032880 231 0.013
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 4 0.013
spermatogenesis GO:0007283 284 0.013
positive regulation of lymphocyte differentiation GO:0045621 61 0.013
regulation of neurotransmitter transport GO:0051588 35 0.012
thymus development GO:0048538 41 0.012
cellular protein catabolic process GO:0044257 155 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
alpha beta t cell activation GO:0046631 91 0.012
response to inorganic substance GO:0010035 96 0.012
ear development GO:0043583 200 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
regulation of transferase activity GO:0051338 263 0.012
positive regulation of secretion GO:0051047 130 0.012
regulation of anatomical structure size GO:0090066 178 0.012
negative regulation of molecular function GO:0044092 258 0.012
carbohydrate metabolic process GO:0005975 230 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
gtp metabolic process GO:0046039 144 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
small molecule biosynthetic process GO:0044283 132 0.012
interleukin 8 production GO:0032637 4 0.012
adult behavior GO:0030534 135 0.012
tyrosine metabolic process GO:0006570 4 0.012
innate immune response GO:0045087 157 0.012
mapk cascade GO:0000165 281 0.012
regulation of response to wounding GO:1903034 189 0.012
glycoprotein biosynthetic process GO:0009101 89 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
forebrain development GO:0030900 302 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
early endosome to late endosome transport GO:0045022 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
male gamete generation GO:0048232 285 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
tissue remodeling GO:0048771 102 0.011
negative regulation of cell activation GO:0050866 111 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
muscle system process GO:0003012 141 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of kinase activity GO:0043549 249 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
natural killer cell mediated cytotoxicity GO:0042267 29 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
negative regulation of cell cycle GO:0045786 123 0.011
cytotoxic t cell degranulation GO:0043316 2 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
multicellular organismal signaling GO:0035637 91 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
negative regulation of cell development GO:0010721 169 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
rna interference GO:0016246 2 0.010
response to organonitrogen compound GO:0010243 246 0.010
germ cell development GO:0007281 185 0.010
cellular response to lipid GO:0071396 145 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
heart morphogenesis GO:0003007 178 0.010
organic hydroxy compound biosynthetic process GO:1901617 77 0.010
lateral inhibition GO:0046331 1 0.010
positive regulation of gtpase activity GO:0043547 85 0.010
anion transport GO:0006820 177 0.010
protein targeting to lysosome GO:0006622 2 0.010

Hps6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.033
disease of anatomical entity DOID:7 0 0.033
immune system disease DOID:2914 0 0.021
sensory system disease DOID:0050155 0 0.016
eye disease DOID:5614 0 0.014
eye and adnexa disease DOID:1492 0 0.014
disease of metabolism DOID:0014667 0 0.013
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.010
bone disease DOID:0080001 0 0.010
neuromuscular disease DOID:440 0 0.010
neuropathy DOID:870 0 0.010