Mus musculus

210 known processes

Fadd

Fas (TNFRSF6)-associated via death domain

(Aliases: Mort1/FADD)

Fadd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
necroptotic process GO:0070266 21 0.765
necrotic cell death GO:0070265 30 0.550
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.485
regulation of cysteine type endopeptidase activity GO:2000116 65 0.485
Human
regulation of necroptotic process GO:0060544 10 0.483
cellular response to dna damage stimulus GO:0006974 207 0.475
negative regulation of necrotic cell death GO:0060547 11 0.386
necroptotic signaling pathway GO:0097527 3 0.380
Human
lymphocyte homeostasis GO:0002260 64 0.378
t cell extravasation GO:0072683 4 0.374
positive regulation of apoptotic process GO:0043065 217 0.371
positive regulation of apoptotic signaling pathway GO:2001235 95 0.359
programmed necrotic cell death GO:0097300 28 0.357
regulation of apoptotic signaling pathway GO:2001233 197 0.355
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.320
apoptotic signaling pathway GO:0097190 306 0.316
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.299
signal transduction in absence of ligand GO:0038034 55 0.286
t cell proliferation GO:0042098 120 0.279
positive regulation of programmed cell death GO:0043068 218 0.262
extrinsic apoptotic signaling pathway GO:0097191 126 0.258
activation of cysteine type endopeptidase activity GO:0097202 27 0.256
Human
homeostasis of number of cells GO:0048872 210 0.246
cellular macromolecule catabolic process GO:0044265 206 0.244
positive regulation of cell death GO:0010942 224 0.238
positive regulation of macrophage differentiation GO:0045651 5 0.236
Human
myeloid cell differentiation GO:0030099 233 0.236
Human
intrinsic apoptotic signaling pathway GO:0097193 132 0.228
regulation of cytokine production GO:0001817 266 0.228
negative regulation of cell cycle GO:0045786 123 0.221
regulation of endopeptidase activity GO:0052548 89 0.221
Human
leukocyte proliferation GO:0070661 172 0.217
regulation of secretion GO:0051046 274 0.209
glial cell apoptotic process GO:0034349 3 0.208
leukocyte homeostasis GO:0001776 79 0.206
lymphocyte differentiation GO:0030098 242 0.185
protein processing GO:0016485 163 0.184
Human
positive regulation of cytokine production GO:0001819 174 0.181
aromatic compound catabolic process GO:0019439 286 0.174
regulation of lymphocyte proliferation GO:0050670 117 0.169
dna catabolic process endonucleolytic GO:0000737 15 0.168
mitochondrion organization GO:0007005 134 0.165
activation induced cell death of t cells GO:0006924 10 0.162
t cell homeostasis GO:0043029 35 0.161
regulation of b cell proliferation GO:0030888 39 0.156
leukocyte apoptotic process GO:0071887 71 0.155
defense response to bacterium GO:0042742 119 0.155
regulation of t cell proliferation GO:0042129 92 0.154
regulation of leukocyte proliferation GO:0070663 121 0.153
zymogen activation GO:0031638 41 0.153
Human
positive regulation of peptidase activity GO:0010952 49 0.152
Human
regulation of interleukin 1 alpha production GO:0032650 4 0.150
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.146
positive regulation of proteolysis GO:0045862 85 0.144
Human
t cell apoptotic process GO:0070231 39 0.143
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.141
positive regulation of protein modification process GO:0031401 299 0.139
lymphocyte proliferation GO:0046651 164 0.133
regulation of interleukin 6 production GO:0032675 55 0.129
regulation of cell cycle GO:0051726 281 0.129
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.127
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.127
regulation of defense response GO:0031347 233 0.125
Human
regulation of hydrolase activity GO:0051336 246 0.125
Human
i kappab kinase nf kappab signaling GO:0007249 85 0.124
Human
dna metabolic process GO:0006259 303 0.123
immune effector process GO:0002252 321 0.121
regulation of myeloid cell differentiation GO:0045637 96 0.120
Human
cellular ketone metabolic process GO:0042180 84 0.119
regulation of cell activation GO:0050865 289 0.118
negative regulation of t cell activation GO:0050868 65 0.117
cellular response to peptidoglycan GO:0071224 4 0.112
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.112
Human
cytokine production GO:0001816 319 0.109
negative regulation of immune system process GO:0002683 209 0.109
positive regulation of interleukin 1 alpha production GO:0032730 4 0.105
defense response to other organism GO:0098542 197 0.104
Human
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.104
Human
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.104
regulation of lymphocyte activation GO:0051249 240 0.103
regulation of necrotic cell death GO:0010939 13 0.103
cellular protein catabolic process GO:0044257 155 0.100
cellular response to lipid GO:0071396 145 0.100
positive regulation of hydrolase activity GO:0051345 148 0.099
Human
negative regulation of lymphocyte activation GO:0051250 91 0.098
regulation of protein transport GO:0051223 163 0.095
interleukin 1 alpha secretion GO:0050703 3 0.093
t cell receptor signaling pathway GO:0050852 46 0.092
negative regulation of protein metabolic process GO:0051248 282 0.092
jnk cascade GO:0007254 72 0.091
regulation of mitotic cell cycle phase transition GO:1901990 73 0.090
macromolecule catabolic process GO:0009057 281 0.089
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.088
negative regulation of lymphocyte proliferation GO:0050672 45 0.088
regulation of macrophage differentiation GO:0045649 9 0.086
Human
negative regulation of b cell activation GO:0050869 27 0.084
cellular amino acid metabolic process GO:0006520 103 0.083
organic cyclic compound catabolic process GO:1901361 295 0.082
toll like receptor signaling pathway GO:0002224 38 0.082
response to organonitrogen compound GO:0010243 246 0.081
leukocyte differentiation GO:0002521 342 0.081
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.081
protein secretion GO:0009306 111 0.080
regulation of peptidase activity GO:0052547 96 0.079
Human
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.078
regulation of secretion by cell GO:1903530 249 0.078
negative regulation of apoptotic signaling pathway GO:2001234 104 0.078
regulation of leukocyte differentiation GO:1902105 159 0.078
Human
cytokine secretion GO:0050663 72 0.076
positive regulation of immature t cell proliferation GO:0033091 4 0.076
organelle assembly GO:0070925 177 0.076
heterocycle catabolic process GO:0046700 280 0.075
protein catabolic process GO:0030163 221 0.074
response to endoplasmic reticulum stress GO:0034976 53 0.074
regulation of interleukin 1 alpha secretion GO:0050705 3 0.074
immune response activating signal transduction GO:0002757 116 0.073
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.073
positive regulation of lymphocyte proliferation GO:0050671 70 0.073
skin development GO:0043588 220 0.073
response to molecule of bacterial origin GO:0002237 143 0.070
positive regulation of interleukin 6 production GO:0032755 37 0.069
regulation of interleukin 8 production GO:0032677 3 0.069
Human
release of cytochrome c from mitochondria GO:0001836 23 0.068
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.068
cellular nitrogen compound catabolic process GO:0044270 280 0.067
positive regulation of defense response GO:0031349 124 0.067
Human
positive regulation of protein phosphorylation GO:0001934 242 0.067
regulation of protein secretion GO:0050708 82 0.066
protein maturation GO:0051604 176 0.066
Human
positive regulation of interleukin 1 secretion GO:0050716 14 0.065
negative regulation of phosphate metabolic process GO:0045936 184 0.065
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.064
regulation of cell cycle phase transition GO:1901987 77 0.064
lymphocyte activation involved in immune response GO:0002285 93 0.063
positive regulation of cytokine secretion GO:0050715 41 0.063
positive regulation of protein secretion GO:0050714 52 0.063
purine nucleoside catabolic process GO:0006152 205 0.062
lymph node development GO:0048535 18 0.061
signal transduction involved in dna damage checkpoint GO:0072422 3 0.061
cell activation involved in immune response GO:0002263 126 0.061
regulation of lymphocyte apoptotic process GO:0070228 41 0.061
t cell activation GO:0042110 289 0.061
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.061
epidermis development GO:0008544 187 0.060
negative regulation of intracellular signal transduction GO:1902532 167 0.059
negative regulation of b cell proliferation GO:0030889 13 0.059
regulation of proteolysis GO:0030162 164 0.058
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
negative regulation of kinase activity GO:0033673 81 0.058
positive regulation of cell activation GO:0050867 158 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.058
positive regulation of interleukin 8 production GO:0032757 2 0.058
Human
regulation of t cell mediated cytotoxicity GO:0001914 18 0.057
regulation of leukocyte apoptotic process GO:2000106 56 0.057
positive regulation of leukocyte proliferation GO:0070665 73 0.057
stress activated mapk cascade GO:0051403 80 0.057
regulation of establishment of protein localization GO:0070201 181 0.057
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.057
negative regulation of protein modification process GO:0031400 163 0.056
regulation of protein localization GO:0032880 231 0.056
positive regulation of endopeptidase activity GO:0010950 43 0.055
Human
positive regulation of secretion by cell GO:1903532 114 0.055
interleukin 6 production GO:0032635 58 0.055
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.054
regulation of kinase activity GO:0043549 249 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
regulation of cell motility GO:2000145 236 0.054
lymphocyte apoptotic process GO:0070227 54 0.054
positive regulation of interferon gamma production GO:0032729 39 0.053
cellular response to lipopolysaccharide GO:0071222 77 0.053
lymphocyte mediated immunity GO:0002449 139 0.053
leukocyte mediated immunity GO:0002443 174 0.053
ripoptosome assembly involved in necroptotic process GO:1901026 6 0.053
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.052
positive regulation of secretion GO:0051047 130 0.052
regulation of b cell activation GO:0050864 81 0.052
negative regulation of leukocyte proliferation GO:0070664 46 0.051
positive regulation of protein transport GO:0051222 93 0.051
mitotic cell cycle process GO:1903047 159 0.050
blood vessel morphogenesis GO:0048514 285 0.050
regulation of t cell extravasation GO:2000407 3 0.050
cellular response to external stimulus GO:0071496 88 0.050
Human
interferon gamma production GO:0032609 67 0.049
epithelial tube morphogenesis GO:0060562 303 0.049
membrane hyperpolarization GO:0060081 21 0.048
interleukin 8 production GO:0032637 4 0.048
Human
negative regulation of phosphorus metabolic process GO:0010563 184 0.048
regulation of protein serine threonine kinase activity GO:0071900 157 0.047
pattern recognition receptor signaling pathway GO:0002221 47 0.047
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.046
b cell activation GO:0042113 161 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
cellular amine metabolic process GO:0044106 44 0.045
response to lipopolysaccharide GO:0032496 128 0.045
regulation of protein deacetylation GO:0090311 17 0.045
regulation of mitochondrial membrane potential GO:0051881 17 0.045
regulation of leukocyte mediated immunity GO:0002703 104 0.044
positive regulation of mapk cascade GO:0043410 170 0.044
response to hypoxia GO:0001666 58 0.044
intracellular receptor signaling pathway GO:0030522 74 0.044
t cell differentiation in thymus GO:0033077 77 0.044
thymus development GO:0048538 41 0.043
cell type specific apoptotic process GO:0097285 268 0.043
spleen development GO:0048536 39 0.043
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.043
cellular response to topologically incorrect protein GO:0035967 25 0.043
b cell proliferation GO:0042100 53 0.042
dna repair GO:0006281 107 0.042
regulation of myeloid leukocyte differentiation GO:0002761 58 0.042
Human
tube formation GO:0035148 140 0.041
nitrogen compound transport GO:0071705 271 0.041
nucleotide metabolic process GO:0009117 332 0.041
compound eye development GO:0048749 1 0.041
negative regulation of transferase activity GO:0051348 85 0.041
regulation of mapk cascade GO:0043408 248 0.040
regulation of t cell differentiation GO:0045580 83 0.040
regulation of membrane potential GO:0042391 192 0.040
response to organophosphorus GO:0046683 22 0.040
regulation of response to wounding GO:1903034 189 0.040
negative regulation of phosphorylation GO:0042326 166 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.039
stress activated protein kinase signaling cascade GO:0031098 81 0.039
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.039
positive regulation of leukocyte differentiation GO:1902107 86 0.039
Human
response to oxidative stress GO:0006979 123 0.039
regulation of cell cycle process GO:0010564 160 0.039
sensory perception of sound GO:0007605 97 0.038
regulation of innate immune response GO:0045088 91 0.038
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.038
toll like receptor 4 signaling pathway GO:0034142 9 0.038
regulation of transferase activity GO:0051338 263 0.038
negative regulation of necroptotic process GO:0060546 9 0.037
macrophage differentiation GO:0030225 20 0.037
Human
membrane depolarization GO:0051899 64 0.037
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.037
neuron apoptotic process GO:0051402 142 0.037
myeloid leukocyte differentiation GO:0002573 119 0.037
Human
myeloid cell homeostasis GO:0002262 114 0.037
regulation of cytokine secretion GO:0050707 61 0.036
positive regulation of immune effector process GO:0002699 107 0.036
protein deacetylation GO:0006476 32 0.036
erk1 and erk2 cascade GO:0070371 77 0.036
mitotic cell cycle GO:0000278 195 0.036
cellular response to hormone stimulus GO:0032870 150 0.036
nucleoside phosphate catabolic process GO:1901292 222 0.036
positive regulation of t cell differentiation GO:0045582 52 0.035
regulation of cellular response to stress GO:0080135 159 0.035
regulation of neuron apoptotic process GO:0043523 122 0.035
regulation of mitotic cell cycle GO:0007346 126 0.035
regulation of cell killing GO:0031341 40 0.035
cytoplasmic transport GO:0016482 234 0.034
alpha beta t cell proliferation GO:0046633 21 0.034
negative regulation of cell activation GO:0050866 111 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
activation of immune response GO:0002253 138 0.034
cellular response to molecule of bacterial origin GO:0071219 83 0.034
interleukin 1 beta secretion GO:0050702 16 0.034
negative regulation of cell cycle phase transition GO:1901988 48 0.034
innate immune response GO:0045087 157 0.033
Human
g1 s transition of mitotic cell cycle GO:0000082 57 0.033
cd8 positive alpha beta cytotoxic t cell extravasation GO:0035698 2 0.033
response to dsrna GO:0043331 30 0.033
antigen receptor mediated signaling pathway GO:0050851 64 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
purine nucleotide catabolic process GO:0006195 211 0.033
regulation of inflammatory response GO:0050727 147 0.033
microtubule based process GO:0007017 236 0.033
inflammatory response GO:0006954 244 0.033
response to atp GO:0033198 8 0.033
positive regulation of interferon alpha production GO:0032727 4 0.033
regulation of erk1 and erk2 cascade GO:0070372 71 0.033
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.032
regulation of alpha beta t cell differentiation GO:0046637 35 0.032
developmental programmed cell death GO:0010623 41 0.032
glycosyl compound metabolic process GO:1901657 246 0.031
amine metabolic process GO:0009308 45 0.031
dna endoreduplication GO:0042023 4 0.031
ion transmembrane transport GO:0034220 361 0.031
protein oligomerization GO:0051259 67 0.031
angiogenesis GO:0001525 201 0.031
response to uv GO:0009411 44 0.031
apoptotic mitochondrial changes GO:0008637 48 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
cellular metal ion homeostasis GO:0006875 151 0.031
epithelial tube formation GO:0072175 130 0.030
interleukin 1 production GO:0032612 31 0.030
cellular homeostasis GO:0019725 240 0.030
protein autophosphorylation GO:0046777 61 0.030
t cell mediated cytotoxicity GO:0001913 26 0.029
gland development GO:0048732 330 0.029
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.029
Human
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.029
interferon beta biosynthetic process GO:0045350 4 0.029
response to radiation GO:0009314 165 0.029
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.029
myotube differentiation GO:0014902 105 0.029
sensory perception GO:0007600 245 0.029
regulation of activated t cell proliferation GO:0046006 16 0.028
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.028
negative regulation of cell cycle process GO:0010948 69 0.028
immune response regulating signaling pathway GO:0002764 125 0.028
protein homooligomerization GO:0051260 43 0.028
cell killing GO:0001906 67 0.028
mapk cascade GO:0000165 281 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
regulation of ion transport GO:0043269 215 0.028
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.028
positive regulation of t cell proliferation GO:0042102 52 0.028
nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070427 5 0.028
regulation of cellular catabolic process GO:0031329 242 0.027
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
dna catabolic process GO:0006308 19 0.027
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.027
cytokine mediated signaling pathway GO:0019221 115 0.027
Human
positive regulation of transferase activity GO:0051347 167 0.027
regulation of organelle organization GO:0033043 289 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
response to organic cyclic compound GO:0014070 198 0.027
er nucleus signaling pathway GO:0006984 27 0.027
immunoglobulin production GO:0002377 73 0.026
cellular ion homeostasis GO:0006873 165 0.026
autophagy GO:0006914 45 0.026
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.026
hepatocyte apoptotic process GO:0097284 11 0.026
regulation of apoptotic dna fragmentation GO:1902510 5 0.026
regulation of interferon beta biosynthetic process GO:0045357 4 0.026
regulation of homeostatic process GO:0032844 182 0.026
negative regulation of mitotic cell cycle GO:0045930 58 0.026
negative regulation of molecular function GO:0044092 258 0.026
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
cellular response to growth factor stimulus GO:0071363 197 0.025
cellular component assembly involved in morphogenesis GO:0010927 139 0.025
embryonic epithelial tube formation GO:0001838 130 0.025
transmembrane transport GO:0055085 412 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
nucleoside catabolic process GO:0009164 206 0.024
anatomical structure homeostasis GO:0060249 145 0.024
regulation of binding GO:0051098 111 0.024
cellular chemical homeostasis GO:0055082 215 0.024
neuron death GO:0070997 154 0.024
interleukin 1 beta production GO:0032611 30 0.024
regulation of reactive oxygen species metabolic process GO:2000377 40 0.024
sensory perception of mechanical stimulus GO:0050954 107 0.024
response to steroid hormone GO:0048545 56 0.023
regulation of intracellular transport GO:0032386 159 0.023
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 22 0.023
cellular response to steroid hormone stimulus GO:0071383 33 0.023
sequestering of calcium ion GO:0051208 18 0.023
cellular response to organic cyclic compound GO:0071407 87 0.023
regulation of t cell apoptotic process GO:0070232 28 0.023
toxin transport GO:1901998 38 0.023
positive regulation of lymphocyte differentiation GO:0045621 61 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
antimicrobial peptide biosynthetic process GO:0002777 2 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
myeloid leukocyte activation GO:0002274 83 0.022
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
positive regulation of neuron death GO:1901216 28 0.022
cellular response to biotic stimulus GO:0071216 92 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
mitochondrial depolarization GO:0051882 6 0.022
response to tumor necrosis factor GO:0034612 26 0.022
cation homeostasis GO:0055080 212 0.022
protein deacylation GO:0035601 36 0.022
interleukin 1 secretion GO:0050701 16 0.022
regulation of jnk cascade GO:0046328 62 0.022
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 6 0.022
interleukin 12 production GO:0032615 32 0.022
response to growth factor GO:0070848 198 0.021
protein localization to organelle GO:0033365 185 0.021
regulation of neuron death GO:1901214 134 0.021
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
positive regulation of necrotic cell death GO:0010940 1 0.020
peptidyl amino acid modification GO:0018193 336 0.020
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.020
negative regulation of dna replication GO:0008156 4 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
regulation of transmembrane transport GO:0034762 128 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.020
response to lipoteichoic acid GO:0070391 6 0.020
regulation of alpha beta t cell proliferation GO:0046640 18 0.020
response to decreased oxygen levels GO:0036293 59 0.020
positive regulation of neuron apoptotic process GO:0043525 25 0.020
response to oxygen levels GO:0070482 62 0.020
positive regulation of response to cytokine stimulus GO:0060760 11 0.020
Human
protein acylation GO:0043543 64 0.020
thymocyte apoptotic process GO:0070242 19 0.020
b cell homeostasis GO:0001782 34 0.020
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.020
ossification GO:0001503 216 0.020
regulation of protein complex assembly GO:0043254 83 0.019
macromolecule deacylation GO:0098732 37 0.019
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
cell cycle g1 s phase transition GO:0044843 57 0.019
regulation of cell migration GO:0030334 219 0.019
response to acid chemical GO:0001101 111 0.019
positive regulation of cell cycle GO:0045787 92 0.019
cd4 positive alpha beta t cell activation GO:0035710 45 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
protein glycosylation GO:0006486 55 0.019
positive regulation of cell motility GO:2000147 116 0.019
exocytosis GO:0006887 121 0.019
neural tube development GO:0021915 160 0.019
organophosphate catabolic process GO:0046434 232 0.019
endoplasmic reticulum unfolded protein response GO:0030968 19 0.019
amide transport GO:0042886 138 0.019
peptidyl serine modification GO:0018209 83 0.018
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.018
regulation of autophagy GO:0010506 30 0.018
regulation of interleukin 1 secretion GO:0050704 15 0.018
muscle tissue development GO:0060537 308 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
Human
cell cycle checkpoint GO:0000075 47 0.018
glycoprotein metabolic process GO:0009100 116 0.018
regulation of interleukin 1 production GO:0032652 26 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
type i interferon production GO:0032606 29 0.018
protein localization to nucleus GO:0034504 121 0.018
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 3 0.018
adaptive immune response GO:0002250 155 0.018
locomotory behavior GO:0007626 195 0.018
regulation of thymocyte apoptotic process GO:0070243 14 0.017
methylation GO:0032259 134 0.017
muscle cell differentiation GO:0042692 261 0.017
regulation of lymphocyte differentiation GO:0045619 107 0.017
dendrite development GO:0016358 115 0.017
glycosylation GO:0070085 62 0.017
regulation of cytokine production involved in immune response GO:0002718 26 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
regulation of interferon gamma production GO:0032649 57 0.017
response to topologically incorrect protein GO:0035966 25 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
nucleotide catabolic process GO:0009166 217 0.017
macromolecule glycosylation GO:0043413 55 0.017
male gamete generation GO:0048232 285 0.017
regulation of t helper 1 cell differentiation GO:0045625 7 0.017
defense response to gram positive bacterium GO:0050830 50 0.017
response to unfolded protein GO:0006986 21 0.017
positive regulation of interleukin 1 beta secretion GO:0050718 14 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
cofactor transport GO:0051181 4 0.017
regulation of striated muscle cell differentiation GO:0051153 81 0.017
leukocyte migration GO:0050900 124 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
guanosine containing compound catabolic process GO:1901069 144 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.016
cell fate commitment GO:0045165 210 0.016
establishment of organelle localization GO:0051656 122 0.016
ectopic germ cell programmed cell death GO:0035234 9 0.016
regulation of alpha beta t cell activation GO:0046634 53 0.016
regulation of protein kinase activity GO:0045859 232 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
epithelial cell proliferation GO:0050673 174 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
response to interleukin 18 GO:0070673 4 0.016
positive regulation of interleukin 12 production GO:0032735 21 0.016
intestinal epithelial structure maintenance GO:0060729 4 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
positive regulation of innate immune response GO:0045089 80 0.016
Human
protein modification by small protein conjugation or removal GO:0070647 207 0.016

Fadd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.266
disease of cellular proliferation DOID:14566 0 0.266
organ system cancer DOID:0050686 0 0.266
thoracic cancer DOID:5093 0 0.214
kidney cancer DOID:263 0 0.082
urinary system cancer DOID:3996 0 0.082
renal cell carcinoma DOID:4450 0 0.082
renal carcinoma DOID:4451 0 0.082
central nervous system disease DOID:331 0 0.036
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
gastrointestinal system cancer DOID:3119 0 0.032
immune system disease DOID:2914 0 0.026
breast cancer DOID:1612 0 0.024